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| | FBXW12 | F-box/WD repeat-containing protein 12. (465 aa) |
| | MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (438 aa) |
| | ZBTB10 | Zinc finger and BTB domain-containing protein 10 isoform X1. (872 aa) |
| | SMC1B | Structural maintenance of chromosomes protein. (1231 aa) |
| | ANAPC11 | Anaphase-promoting complex subunit 11. (84 aa) |
| | WEE1 | Wee1-like protein kinase. (646 aa) |
| | SMAD2 | Mothers against decapentaplegic homolog. (467 aa) |
| | CCND1 | G1/S-specific cyclin-D1; Belongs to the cyclin family. (295 aa) |
| | MCM5 | DNA helicase; Belongs to the MCM family. (734 aa) |
| | CDK4 | Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa) |
| | CDK2 | Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily. (298 aa) |
| | CDKN1C | Cyclin-dependent kinase inhibitor 1C. (263 aa) |
| | CDC25A | M-phase inducer phosphatase 1. (522 aa) |
| | PLK1 | Serine/threonine-protein kinase PLK. (604 aa) |
| | ESPL1 | Separin. (2103 aa) |
| | STAG2 | Cohesin subunit SA-2 isoform X2. (1268 aa) |
| | SMAD4 | Mothers against decapentaplegic homolog. (552 aa) |
| | HDAC1 | Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (482 aa) |
| | SFN | 14-3-3 protein sigma; Belongs to the 14-3-3 family. (248 aa) |
| | TMEM82 | Transmembrane protein 82. (344 aa) |
| | CDKN2C | Cyclin-dependent kinase 4 inhibitor C. (168 aa) |
| | ORC5 | Origin recognition complex subunit 5. (435 aa) |
| | CDKN1A | Cyclin-dependent kinase inhibitor 1. (161 aa) |
| | ZBTB17 | Zinc finger and BTB domain-containing protein 17. (775 aa) |
| | ZBTB46 | Zinc finger and BTB domain-containing protein 46. (589 aa) |
| | ORC1 | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (863 aa) |
| | CDC20 | Cell division cycle protein 20 homolog. (499 aa) |
| | E2F2 | Transcription factor E2F2. (449 aa) |
| | MAD2L2 | Mitotic spindle assembly checkpoint protein MAD2B. (211 aa) |
| | SNAPIN | SNARE-associated protein Snapin. (137 aa) |
| | LOC110572649 | Cyclin-dependent kinase inhibitor 2A-like. (152 aa) |
| | CCNA2 | cyclin-A2; Belongs to the cyclin family. (432 aa) |
| | MCM7 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (672 aa) |
| | CDK3 | Cyclin-dependent kinase 3 isoform X1; Belongs to the protein kinase superfamily. (452 aa) |
| | ANAPC4 | Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. (808 aa) |
| | MAD1L1 | Mitotic spindle assembly checkpoint protein MAD1 isoform X2. (717 aa) |
| | GADD45A | Growth arrest and DNA damage-inducible protein GADD45 alpha. (165 aa) |
| | CCNB3 | G2/mitotic-specific cyclin-B3; Belongs to the cyclin family. (1324 aa) |
| | TFDP2 | Transcription factor. (335 aa) |
| | TGFB3 | Transforming growth factor beta-3. (461 aa) |
| | ATR | Serine/threonine-protein kinase ATR; Belongs to the PI3/PI4-kinase family. (2643 aa) |
| | MDM2 | E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (487 aa) |
| | ANAPC10 | Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. (185 aa) |
| | CDC14B | Dual specificity protein phosphatase CDC14B. (508 aa) |
| | STAG1 | Cohesin subunit SA-1. (1258 aa) |
| | ZBTB47 | Zinc finger and BTB domain-containing protein 47. (774 aa) |
| | ANAPC13 | Anaphase-promoting complex subunit 13. (74 aa) |
| | CDC27 | Cell division cycle protein 27 homolog. (825 aa) |
| | CCNA1 | cyclin-A1; Belongs to the cyclin family. (421 aa) |
| | CDC16 | Cell division cycle protein 16 homolog isoform X1. (620 aa) |
| | ATM | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3054 aa) |
| | CREBBP | CREB-binding protein isoform X3. (2433 aa) |
| | CHEK1 | Serine/threonine-protein kinase Chk1 isoform X1; Belongs to the protein kinase superfamily. (476 aa) |
| | ANAPC7 | Anaphase-promoting complex subunit 7. (601 aa) |
| | E2F3 | Transcription factor E2F3 isoform X1. (466 aa) |
| | CCNH | cyclin-H isoform X1; Belongs to the cyclin family. (328 aa) |
| | ANAPC1 | Anaphase-promoting complex subunit 1. (1944 aa) |
| | PTTG1 | Securin isoform X1. (201 aa) |
| | PKMYT1 | Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase isoform X1; Belongs to the protein kinase superfamily. (494 aa) |
| | CDK1 | Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily. (297 aa) |
| | BUB1 | Mitotic checkpoint serine/threonine-protein kinase BUB1. (1084 aa) |
| | TGFB2 | Transforming growth factor beta; Belongs to the TGF-beta family. (414 aa) |
| | ANAPC5 | Anaphase-promoting complex subunit 5 isoform X1. (755 aa) |
| | TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa) |
| | CCNE1 | G1/S-specific cyclin-E1 isoform X1; Belongs to the cyclin family. (410 aa) |
| | CDC23 | Cell division cycle protein 23 homolog. (597 aa) |
| | SMC3 | Structural maintenance of chromosomes protein. (1217 aa) |
| | CDC25C | M-phase inducer phosphatase 3. (529 aa) |
| | CDK7 | Cyclin-dependent kinase 7 isoform X1; Belongs to the protein kinase superfamily. (356 aa) |
| | YWHAG | 14-3-3 protein gamma; Belongs to the 14-3-3 family. (247 aa) |
| | SKP1 | S-phase kinase-associated protein 1; Belongs to the SKP1 family. (163 aa) |
| | CNTD2 | Cyclin N-terminal domain-containing protein 2; Belongs to the cyclin family. (329 aa) |
| | MYNN | Myoneurin. (610 aa) |
| | CCNB1 | G2/mitotic-specific cyclin-B1; Belongs to the cyclin family. (427 aa) |
| | ORC4 | Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (436 aa) |
| | ORC2 | Origin recognition complex subunit 2. (578 aa) |
| | CHEK2 | Serine/threonine-protein kinase Chk2. (544 aa) |
| | YWHAH | 14-3-3 protein eta; Belongs to the 14-3-3 family. (246 aa) |
| | SMC1A | Structural maintenance of chromosomes protein. (1233 aa) |
| | BUB3 | Mitotic checkpoint protein BUB3 isoform X1. (328 aa) |
| | CDC20B | Cell division cycle protein 20 homolog B. (547 aa) |
| | ZNF652 | Zinc finger protein 652. (608 aa) |
| | FZR1 | Fizzy-related protein homolog isoform X1. (496 aa) |
| | CDKN2D | Cyclin-dependent kinase 4 inhibitor D. (166 aa) |
| | FAM126B | Protein FAM126B isoform X3. (585 aa) |
| | RBL2 | Retinoblastoma-like protein 2 isoform X1. (1139 aa) |
| | CDC6 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (559 aa) |
| | E2F4 | Transcription factor E2F4 isoform X1. (399 aa) |
| | YWHAE | 14-3-3 protein epsilon; Belongs to the 14-3-3 family. (255 aa) |
| | ORC6 | Origin recognition complex subunit 6. (252 aa) |
| | GADD45B | Growth arrest and DNA damage-inducible protein GADD45 beta. (160 aa) |
| | E2F1 | LOW QUALITY PROTEIN: transcription factor E2F1. (483 aa) |
| | SNPH | Syntaphilin. (538 aa) |
| | CDC14A | Dual specificity protein phosphatase CDC14A. (624 aa) |
| | CDC7 | Cell division cycle 7-related protein kinase. (575 aa) |
| | DBF4 | LOW QUALITY PROTEIN: protein DBF4 homolog A. (676 aa) |
| | MAD2L1 | LOW QUALITY PROTEIN: mitotic spindle assembly checkpoint protein MAD2A. (111 aa) |
| | MCM3 | DNA helicase; Belongs to the MCM family. (808 aa) |
| | GSK3B | Glycogen synthase kinase-3 beta isoform X1; Belongs to the protein kinase superfamily. (433 aa) |
| | CDKN1B | Cyclin-dependent kinase inhibitor 1B. (198 aa) |
| | CUL1 | Cullin-1 isoform X1; Belongs to the cullin family. (801 aa) |
| | TFDP1 | Transcription factor. (410 aa) |
| | YWHAQ | 14-3-3 protein theta; Belongs to the 14-3-3 family. (245 aa) |
| | MCM2 | DNA helicase; Belongs to the MCM family. (903 aa) |
| | SKP2 | S-phase kinase-associated protein 2 isoform X1. (436 aa) |
| | HDAC2 | Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (488 aa) |
| | SMAD3 | Mothers against decapentaplegic homolog. (425 aa) |
| | LOC110585554 | Mitotic checkpoint serine/threonine-protein kinase BUB1 beta-like. (190 aa) |
| | LOC110585553 | Mitotic checkpoint serine/threonine-protein kinase BUB1 beta-like. (147 aa) |
| | MCM6 | DNA helicase; Belongs to the MCM family. (821 aa) |
| | LOC110583310 | Mothers against decapentaplegic homolog. (451 aa) |
| | LOC110585284 | Mitotic checkpoint serine/threonine-protein kinase BUB1 beta-like. (203 aa) |
| | WEE2 | Wee1-like protein kinase. (566 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (381 aa) |
| | LOC110584379 | F-box/WD repeat-containing protein 12-like isoform X1. (215 aa) |
| | GADD45G | Growth arrest and DNA damage-inducible protein GADD45 gamma isoform X1. (175 aa) |
| | CDK20 | Cyclin-dependent kinase 20 isoform X1; Belongs to the protein kinase superfamily. (346 aa) |
| | CCNB2 | G2/mitotic-specific cyclin-B2; Belongs to the cyclin family. (397 aa) |
| | CCND3 | G1/S-specific cyclin-D3; Belongs to the cyclin family. (291 aa) |
| | TTK | Dual specificity protein kinase TTK. (851 aa) |
| | ORC3 | Origin recognition complex subunit 3. (756 aa) |
| | AP5S1 | AP-5 complex subunit sigma-1. (200 aa) |
| | CDC26 | Anaphase-promoting complex subunit CDC26. (85 aa) |
| | ABL1 | Tyrosine-protein kinase. (1137 aa) |
| | ANAPC2 | Anaphase-promoting complex subunit 2 isoform X1; Belongs to the cullin family. (818 aa) |
| | RAD21L1 | Double-strand-break repair protein rad21-like protein 1. (554 aa) |
| | CDC45 | Cell division control protein 45 homolog. (567 aa) |
| | MCM4 | DNA helicase; Belongs to the MCM family. (863 aa) |
| | E2F5 | Transcription factor E2F5 isoform X1. (346 aa) |
| | CCND2 | G1/S-specific cyclin-D2; Belongs to the cyclin family. (289 aa) |
| | LOC110580531 | Cohesin subunit SA-2-like. (178 aa) |
| | CDK6 | Cyclin-dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa) |
| | RBX1 | E3 ubiquitin-protein ligase RBX1. (108 aa) |
| | RB1 | Retinoblastoma-associated protein. (934 aa) |
| | PCNA | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa) |
| | RBL1 | Retinoblastoma-like protein 1. (1068 aa) |
| | CDC25B | LOW QUALITY PROTEIN: M-phase inducer phosphatase 2. (574 aa) |
| | YWHAB | 14-3-3 protein beta/alpha; Belongs to the 14-3-3 family. (244 aa) |
| | EP300 | Histone acetyltransferase p300. (2420 aa) |
| | RAD21 | Double-strand-break repair protein rad21 homolog. (631 aa) |
| | CCNE2 | G1/S-specific cyclin-E2; Belongs to the cyclin family. (404 aa) |
| | YWHAZ | 14-3-3 protein zeta/delta; Belongs to the 14-3-3 family. (245 aa) |
| | PRKDC | DNA-dependent protein kinase catalytic subunit; Belongs to the PI3/PI4-kinase family. (4135 aa) |
| | LOC110578916 | Cohesin subunit SA-2-like. (146 aa) |
