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| | CFTR | Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1573 aa) |
| | INSR | Tyrosine-protein kinase receptor. (1368 aa) |
| | ACACA | LOW QUALITY PROTEIN: acetyl-CoA carboxylase 1. (2346 aa) |
| | PRKAG1 | 5'-AMP-activated protein kinase subunit gamma-1. (330 aa) |
| | PFKM | ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (853 aa) |
| | ACACB | acetyl-CoA carboxylase 2. (2456 aa) |
| | RPS6KB1 | Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa) |
| | PRKAG3 | 5'-AMP-activated protein kinase subunit gamma-3. (485 aa) |
| | STK11 | Serine/threonine-protein kinase STK11 isoform X1. (596 aa) |
| | EEF2 | Elongation factor 2. (858 aa) |
| | CREB3L3 | Cyclic AMP-responsive element-binding protein 3-like protein 3. (302 aa) |
| | ELAVL1 | ELAV-like protein; Belongs to the RRM elav family. (326 aa) |
| | PRKAB1 | 5'-AMP-activated protein kinase subunit beta-1. (270 aa) |
| | RHEBL1 | GTPase RhebL1. (183 aa) |
| | PPP2CA | Serine/threonine-protein phosphatase. (309 aa) |
| | SCD5 | stearoyl-CoA desaturase 5; Belongs to the fatty acid desaturase type 1 family. (330 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) |
| | CREB1 | Cyclic AMP-responsive element-binding protein 1. (327 aa) |
| | G6PC2 | Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (356 aa) |
| | STRADB | STE20-related kinase adapter protein beta. (415 aa) |
| | MLYCD | malonyl-CoA decarboxylase, mitochondrial. (499 aa) |
| | PPP2R2B | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (446 aa) |
| | PIK3R1 | Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (725 aa) |
| | HMGCR | 3-hydroxy-3-methylglutaryl coenzyme A reductase. (887 aa) |
| | SCD | acyl-CoA desaturase; Belongs to the fatty acid desaturase type 1 family. (359 aa) |
| | PFKFB1 | 6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase 1 isoform X1. (471 aa) |
| | SIRT1 | NAD-dependent protein deacetylase sirtuin-1. (746 aa) |
| | TBC1D1 | TBC1 domain family member 1 isoform X1. (1058 aa) |
| | PPP2R5E | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (467 aa) |
| | ADRA1A | LOW QUALITY PROTEIN: alpha-1A adrenergic receptor. (465 aa) |
| | RAB10 | Ras-related protein Rab-10. (200 aa) |
| | LEP | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa) |
| | LIPE | Hormone-sensitive lipase isoform X1. (806 aa) |
| | PPP2R2A | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (447 aa) |
| | CAMKK2 | Calcium/calmodulin-dependent protein kinase kinase 2. (578 aa) |
| | TSC2 | Tuberin isoform X1. (1789 aa) |
| | PDPK1 | 3-phosphoinositide-dependent protein kinase 1. (571 aa) |
| | GAREM2 | GRB2-associated and regulator of MAPK protein 2. (400 aa) |
| | RAB2B | Ras-related protein Rab-2B. (216 aa) |
| | ULK1 | Serine/threonine-protein kinase ULK1. (1054 aa) |
| | PFKFB3 | 6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase 3 isoform X1. (519 aa) |
| | SLC2A4 | Solute carrier family 2, facilitated glucose transporter member 4 isoform X1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (509 aa) |
| | PRKAA1 | Non-specific serine/threonine protein kinase. (574 aa) |
| | PPP2R1B | Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform isoform X2. (693 aa) |
| | IRS2 | Insulin receptor substrate 2. (1330 aa) |
| | LOC110583219 | Adiponectin receptor protein 1. (159 aa) |
| | PCK2 | Phosphoenolpyruvate carboxykinase [GTP], mitochondrial. (640 aa) |
| | PPP2R3C | Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma isoform X1. (450 aa) |
| | PPARG | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (542 aa) |
| | RHEB | GTP-binding protein Rheb. (184 aa) |
| | SREBF1 | Sterol regulatory element-binding protein 1 isoform X3. (1180 aa) |
| | ADIPOQ | Adiponectin. (244 aa) |
| | PPP2CB | Serine/threonine-protein phosphatase. (309 aa) |
| | FOXO3 | Forkhead box protein O3. (672 aa) |
| | MAP3K7 | Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa) |
| | RAB14 | Ras-related protein Rab-14. (215 aa) |
| | PRKAG2 | 5'-AMP-activated protein kinase subunit gamma-2. (568 aa) |
| | CREB3L2 | Cyclic AMP-responsive element-binding protein 3-like protein 2. (520 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
| | PPP2R5D | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (676 aa) |
| | TSC1 | Hamartin. (1168 aa) |
| | CREB3 | Cyclic AMP-responsive element-binding protein 3 isoform X2. (352 aa) |
| | PPP2R3B | Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta. (356 aa) |
| | PFKP | ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (790 aa) |
| | ADIPOR2 | Adiponectin receptor protein 2. (386 aa) |
| | GYS2 | Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan. (703 aa) |
| | LOC110580711 | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (600 aa) |
| | CAB39 | Calcium-binding protein 39 isoform X1. (341 aa) |
| | CREB5 | Cyclic AMP-responsive element-binding protein 5. (501 aa) |
| | IGF1 | Insulin-like growth factor I isoform X1. (185 aa) |
| | CD36 | Platelet glycoprotein 4; Belongs to the CD36 family. (472 aa) |
| | CAB39L | Calcium-binding protein 39-like. (337 aa) |
| | LOC110579716 | GRB2-associated and regulator of MAPK protein 2. (367 aa) |
| | PFKFB4 | 6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase 4 isoform X1. (469 aa) |
| | HNF4A | Hepatocyte nuclear factor 4-alpha isoform X1. (474 aa) |
| | RAB2A | Ras-related protein Rab-2A. (212 aa) |
| | PRKAB2 | 5'-AMP-activated protein kinase subunit beta-2. (272 aa) |
| | CPT1B | Carnitine O-palmitoyltransferase 1, muscle isoform isoform X1; Belongs to the carnitine/choline acetyltransferase family. (772 aa) |
| | CCND1 | G1/S-specific cyclin-D1; Belongs to the cyclin family. (295 aa) |
| | CPT1A | Carnitine O-palmitoyltransferase 1, liver isoform isoform X1; Belongs to the carnitine/choline acetyltransferase family. (773 aa) |
| | INS | Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa) |
| | LOC110577702 | Proline-rich AKT1 substrate 1. (126 aa) |
| | PPP2R5B | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (497 aa) |
| | EEF2K | Eukaryotic elongation factor 2 kinase. (725 aa) |
| | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa) |
| | PIK3R3 | Phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1. (507 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR. (2557 aa) |
| | RPS6KB2 | Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (483 aa) |
| | CREB3L1 | Cyclic AMP-responsive element-binding protein 3-like protein 1. (520 aa) |
| | PRKAA2 | Non-specific serine/threonine protein kinase. (552 aa) |
| | PPP2R5A | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (486 aa) |
| | PIK3R2 | Phosphatidylinositol 3-kinase regulatory subunit beta isoform X1. (726 aa) |
| | EIF4EBP1 | Eukaryotic translation initiation factor 4E-binding protein 1. (118 aa) |
| | IRS1 | Insulin receptor substrate 1. (1236 aa) |
| | CPT1C | Carnitine O-palmitoyltransferase 1, brain isoform; Belongs to the carnitine/choline acetyltransferase family. (803 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | G6PC | Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (357 aa) |
| | PFKFB2 | 6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase 2. (517 aa) |
| | LOC110572711 | Proline-rich AKT1 substrate 1-like. (173 aa) |
| | CRTC2 | CREB-regulated transcription coactivator 2. (695 aa) |
| | CREB3L4 | Cyclic AMP-responsive element-binding protein 3-like protein 4 isoform X2. (394 aa) |
| | RPTOR | Regulatory-associated protein of mTOR. (1335 aa) |
| | G6PC3 | Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (346 aa) |
| | CCNA2 | cyclin-A2; Belongs to the cyclin family. (432 aa) |
| | PPP2R1A | Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform isoform X1. (589 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) |
| | GYS1 | Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan. (737 aa) |
| | PPP2R5C | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (524 aa) |
| | FASN | Fatty acid synthase. (2519 aa) |
| | IGF1R | Tyrosine-protein kinase receptor. (1367 aa) |
| | PPARGC1A | Peroxisome proliferator-activated receptor gamma coactivator 1-alpha isoform X1. (803 aa) |
| | PPP2R3A | Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha. (1153 aa) |
| | LOC110571849 | Insulin receptor substrate 1-like. (404 aa) |
| | LEPR | Leptin receptor. (1166 aa) |
| | PIK3CB | LOW QUALITY PROTEIN: phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform; Belongs to the PI3/PI4-kinase family. (1070 aa) |
| | PFKL | ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (780 aa) |
| | PPP2R2C | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (447 aa) |
| | FBP1 | Fructose-1,6-bisphosphatase 1; Belongs to the FBPase class 1 family. (338 aa) |
| | IRS4 | Insulin receptor substrate 4. (1244 aa) |
| | STRADA | STE20-related kinase adapter protein alpha isoform X2. (431 aa) |
| | FOXO1 | Forkhead box protein O1. (663 aa) |
| | CCNA1 | cyclin-A1; Belongs to the cyclin family. (421 aa) |
| | FBP2 | Fructose-1,6-bisphosphatase isozyme 2; Belongs to the FBPase class 1 family. (339 aa) |
| | PCK1 | Phosphoenolpyruvate carboxykinase, cytosolic [GTP] isoform X1. (622 aa) |
