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| | EXOG | Nuclease EXOG, mitochondrial isoform X1. (368 aa) |
| | CTSZ | Cathepsin Z; Belongs to the peptidase C1 family. (333 aa) |
| | LOC110569925 | Cathepsin L1; Belongs to the peptidase C1 family. (334 aa) |
| | LOC110569942 | Cathepsin L1-like isoform X1; Belongs to the peptidase C1 family. (335 aa) |
| | PARP4 | Poly [ADP-ribose] polymerase. (1747 aa) |
| | IL3RA | Interleukin-3 receptor subunit alpha. (376 aa) |
| | ERAS | GTPase ERas. (233 aa) |
| | LOC110569944 | Cathepsin L1-like; Belongs to the peptidase C1 family. (333 aa) |
| | CAPN8 | LOW QUALITY PROTEIN: calpain-8; Belongs to the peptidase C2 family. (704 aa) |
| | CAPN2 | Calpain-2 catalytic subunit; Belongs to the peptidase C2 family. (700 aa) |
| | ERN1 | Serine/threonine-protein kinase/endoribonuclease IRE1. (975 aa) |
| | FOS | Proto-oncogene c-Fos. (380 aa) |
| | PIK3CB | LOW QUALITY PROTEIN: phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform; Belongs to the PI3/PI4-kinase family. (1070 aa) |
| | GADD45A | Growth arrest and DNA damage-inducible protein GADD45 alpha. (165 aa) |
| | LOC110572248 | Perforin-1-like. (555 aa) |
| | EIF2S1 | Eukaryotic translation initiation factor 2 subunit 1. (315 aa) |
| | CTSH | Pro-cathepsin H; Belongs to the peptidase C1 family. (335 aa) |
| | PARP1 | Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1014 aa) |
| | BIRC5 | Baculoviral IAP repeat-containing protein 5. (142 aa) |
| | BBC3 | Bcl-2-binding component 3. (193 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) |
| | BAX | Apoptosis regulator BAX isoform X1. (192 aa) |
| | NFKB1 | Nuclear factor NF-kappa-B p105 subunit isoform X4. (987 aa) |
| | HTRA4 | LOW QUALITY PROTEIN: serine protease HTRA4. (490 aa) |
| | IKBKB | Inhibitor of nuclear factor kappa-B kinase subunit beta. (756 aa) |
| | BCL2A1 | Bcl-2-related protein A1. (210 aa) |
| | ACTB | Actin, cytoplasmic 1. (375 aa) |
| | SPTA1 | Spectrin alpha chain, erythrocytic 1. (2411 aa) |
| | LMNA | Lamin; Belongs to the intermediate filament family. (666 aa) |
| | ACTG1 | Actin, cytoplasmic 2. (375 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | IKBKG | NF-kappa-B essential modulator. (419 aa) |
| | MAP3K14 | Mitogen-activated protein kinase kinase kinase 14. (955 aa) |
| | PIK3R2 | Phosphatidylinositol 3-kinase regulatory subunit beta isoform X1. (726 aa) |
| | NTRK1 | Tyrosine-protein kinase receptor. (796 aa) |
| | LOC110574076 | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa) |
| | JUN | Transcription factor AP-1 isoform X1; Belongs to the bZIP family. (335 aa) |
| | DFFA | DNAation factor subunit alpha isoform X1. (346 aa) |
| | SUCO | SUN domain-containing ossification factor. (1442 aa) |
| | FASLG | Tumor necrosis factor ligand superfamily member 6 isoform X1; Belongs to the tumor necrosis factor family. (281 aa) |
| | BAK1 | Bcl-2 homologous antagonist/killer. (211 aa) |
| | DAXX | Death domain-associated protein 6. (750 aa) |
| | ITPR3 | Inositol 1,4,5-trisphosphate receptor type 3. (2584 aa) |
| | ACTL8 | Actin-like protein 8; Belongs to the actin family. (366 aa) |
| | RELA | Transcription factor p65. (531 aa) |
| | FADD | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (218 aa) |
| | CTSF | LOW QUALITY PROTEIN: cathepsin F; Belongs to the peptidase C1 family. (489 aa) |
| | DFFB | DNAation factor subunit beta. (393 aa) |
| | CTSW | Cathepsin W; Belongs to the peptidase C1 family. (385 aa) |
| | CASP9 | Caspase-9; Belongs to the peptidase C14A family. (447 aa) |
| | CAPN1 | Calpain-1 catalytic subunit; Belongs to the peptidase C2 family. (715 aa) |
| | AIFM1 | Apoptosis-inducing factor 1, mitochondrial. (613 aa) |
| | PIK3R3 | Phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1. (507 aa) |
| | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa) |
| | BCL2 | Apoptosis regulator Bcl-2 isoform X1. (234 aa) |
| | PPP1R14B | LOW QUALITY PROTEIN: protein phosphatase 1 regulatory subunit 14B-like. (203 aa) |
| | CASP6 | Caspase-6 isoform X1; Belongs to the peptidase C14A family. (293 aa) |
| | LOC110576070 | Tumor necrosis factor receptor superfamily member 1A-like isoform X1. (459 aa) |
| | ERN2 | Serine/threonine-protein kinase/endoribonuclease IRE2. (926 aa) |
| | BAD | Bcl2-associated agonist of cell death isoform X1. (205 aa) |
| | DDIT3 | DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (168 aa) |
| | GADD45B | Growth arrest and DNA damage-inducible protein GADD45 beta. (160 aa) |
| | APAF1 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1250 aa) |
| | CSF2RB | Cytokine receptor common subunit beta. (863 aa) |
| | HPS5 | Hermansky-Pudlak syndrome 5 protein. (784 aa) |
| | LOC110578349 | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (415 aa) |
| | CTSS | Cathepsin S; Belongs to the peptidase C1 family. (340 aa) |
| | CTSK | Cathepsin K isoform X2; Belongs to the peptidase C1 family. (330 aa) |
| | MCL1 | LOW QUALITY PROTEIN: induced myeloid leukemia cell differentiation protein Mcl-1. (347 aa) |
| | PMAIP1 | Phorbol-12-myristate-13-acetate-induced protein 1. (54 aa) |
| | XIAP | E3 ubiquitin-protein ligase XIAP. (497 aa) |
| | LOC110577330 | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa) |
| | ATF4 | Cyclic AMP-dependent transcription factor ATF-4. (351 aa) |
| | MAPK1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (361 aa) |
| | LOC110579927 | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa) |
| | CUNH7orf31 | Uncharacterized protein C7orf31 homolog. (590 aa) |
| | MAPK9 | Mitogen-activated protein kinase. (424 aa) |
| | CSDE1 | Cold shock domain-containing protein E1 isoform X1. (798 aa) |
| | NGF | Beta-nerve growth factor; Belongs to the NGF-beta family. (241 aa) |
| | PIDD1 | P53-induced death domain-containing protein 1. (915 aa) |
| | BID | BH3-interacting domain death agonist; Counters the protective effect of Bcl-2. (240 aa) |
| | TUBA8 | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa) |
| | KRAS | GTPase KRas. (188 aa) |
| | TNFRSF1A | Tumor necrosis factor receptor superfamily member 1A. (451 aa) |
| | GEM | GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (295 aa) |
| | ITPR2 | Inositol 1,4,5-trisphosphate receptor type 2. (2701 aa) |
| | TRAF2 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (523 aa) |
| | TRAF1 | TNF receptor-associated factor. (415 aa) |
| | LOC110579961 | Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | BCL2L1 | Bcl-2-like protein 1 isoform X1. (233 aa) |
| | REM1 | GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (298 aa) |
| | SPTAN1 | Spectrin alpha chain, non-erythrocytic 1 isoform X1. (2478 aa) |
| | NRAS | GTPase NRas. (189 aa) |
| | CTSC | Dipeptidyl peptidase 1 isoform X1; Belongs to the peptidase C1 family. (461 aa) |
| | LOC110582054 | Hermansky-Pudlak syndrome 5 protein-like. (313 aa) |
| | CAPN11 | Calpain-11; Belongs to the peptidase C2 family. (702 aa) |
| | HRAS | GTPase HRas isoform X1. (189 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
| | IFITM10 | Interferon-induced transmembrane protein 10. (176 aa) |
| | MAP3K5 | Mitogen-activated protein kinase kinase kinase 5. (1366 aa) |
| | ENDOG | Endonuclease. (300 aa) |
| | LOC110583436 | Cathepsin L1-like; Belongs to the peptidase C1 family. (218 aa) |
| | LOC110581877 | Disabled homolog 2-interacting protein isoform X1. (1065 aa) |
| | MAP2K1 | Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa) |
| | CASP3 | Caspase-3 isoform X1; Belongs to the peptidase C14A family. (302 aa) |
| | GADD45G | Growth arrest and DNA damage-inducible protein GADD45 gamma isoform X1. (175 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (381 aa) |
| | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1 isoform X1. (2709 aa) |
| | RAF1 | RAF proto-oncogene serine/threonine-protein kinase. (648 aa) |
| | CASP2 | Caspase-2; Belongs to the peptidase C14A family. (452 aa) |
| | LOC110582885 | Cathepsin E-like. (174 aa) |
| | PARP2 | Poly [ADP-ribose] polymerase. (566 aa) |
| | CAPN3 | Calpain-3 isoform X2; Belongs to the peptidase C2 family. (821 aa) |
| | FAS | Tumor necrosis factor receptor superfamily member 6. (314 aa) |
| | CAPN9 | Calpain-9; Belongs to the peptidase C2 family. (674 aa) |
| | CENPU | Centromere protein U. (403 aa) |
| | LOC110586231 | Caspase-12-like; Belongs to the peptidase C14A family. (389 aa) |
| | BIRC3 | Baculoviral IAP repeat-containing protein 3 isoform X1. (604 aa) |
| | TUBAL3 | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (382 aa) |
| | RIPK1 | Receptor-interacting serine/threonine-protein kinase 1. (665 aa) |
| | TNF | Tumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa) |
| | EIF2AK3 | Eukaryotic translation initiation factor 2-alpha kinase 3. (1114 aa) |
| | PARP3 | Poly [ADP-ribose] polymerase. (536 aa) |
| | NFKBIA | NF-kappa-B inhibitor alpha. (314 aa) |
| | BCL2L11 | Bcl-2-like protein 11 isoform X1. (131 aa) |
| | CAPN14 | Calpain-14; Belongs to the peptidase C2 family. (685 aa) |
| | CAPN13 | LOW QUALITY PROTEIN: calpain-13; Belongs to the peptidase C2 family. (562 aa) |
| | PDPK1 | 3-phosphoinositide-dependent protein kinase 1. (571 aa) |
| | ATM | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3054 aa) |
| | BIRC2 | Baculoviral IAP repeat-containing protein 2. (619 aa) |
| | DIABLO | Diablo homolog, mitochondrial isoform X1. (237 aa) |
| | HRK | Activator of apoptosis harakiri; Promotes apoptosis. (91 aa) |
| | CTSB | Cathepsin B; Belongs to the peptidase C1 family. (339 aa) |
| | CTSO | Cathepsin O isoform X1; Belongs to the peptidase C1 family. (321 aa) |
| | CHUK | Inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1. (744 aa) |
| | MAPK8 | Mitogen-activated protein kinase. (427 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa) |
| | CAPN12 | Calpain-12; Belongs to the peptidase C2 family. (721 aa) |
| | HTRA2 | Serine protease HTRA2, mitochondrial. (458 aa) |
| | LMNB1 | lamin-B1; Belongs to the intermediate filament family. (586 aa) |
| | CASP7 | Caspase-7 isoform X1; Belongs to the peptidase C14A family. (301 aa) |
| | PIK3R1 | Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (725 aa) |
| | LOC110591391 | Mitogen-activated protein kinase 10-like. (176 aa) |
| | LOC110591392 | Mitogen-activated protein kinase. (300 aa) |
| | PTPN13 | Tyrosine-protein phosphatase non-receptor type 13 isoform X1. (2501 aa) |
| | LOC110592054 | Cytochrome c, testis-specific; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | CASP10 | Caspase-10; Belongs to the peptidase C14A family. (481 aa) |
| | CFLAR | CASP8 and FADD-like apoptosis regulator; Belongs to the peptidase C14A family. (482 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) |
| | TRADD | Tumor necrosis factor receptor type 1-associated DEATH domain protein isoform X1. (312 aa) |
| | RRAD | GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (308 aa) |
| | SEPT4 | Septin-4 isoform X2; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (457 aa) |
| | CUNH17orf47 | LOW QUALITY PROTEIN: uncharacterized protein C17orf47 homolog. (571 aa) |
| | LOC110591202 | Interleukin-3-like. (143 aa) |
| | ACTBL2 | Beta-actin-like protein 2 isoform X1. (376 aa) |
| | LOC110592113 | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (448 aa) |
| | CASP8 | LOW QUALITY PROTEIN: caspase-8; Belongs to the peptidase C14A family. (486 aa) |
| | LOC110593538 | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa) |
| | LOC110593609 | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa) |
| | TNFSF10 | Tumor necrosis factor ligand superfamily member. (286 aa) |
| | LMNB2 | lamin-B2; Belongs to the intermediate filament family. (569 aa) |
| | LOC110593537 | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa) |
| | MAP2K2 | Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa) |
| | HTRA1 | Serine protease HTRA1. (464 aa) |
| | TUBA1C | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa) |
| | LOC110594317 | Caspase-14-like; Belongs to the peptidase C14A family. (369 aa) |
