STRINGSTRING
EFNA3 EFNA3 EFNA2 EFNA2 PLCG2 PLCG2 RND1 RND1 NFATC3 NFATC3 LOC110592869 LOC110592869 SEMA6B SEMA6B PAK1 PAK1 LOC110593176 LOC110593176 SEMA5A SEMA5A SEMA6A SEMA6A EPHA5 EPHA5 PARD6A PARD6A CAMK2B CAMK2B LIMK2 LIMK2 SSH1 SSH1 EPHA4 EPHA4 PAK4 PAK4 BMPR2 BMPR2 PDK1 PDK1 SEMA4C SEMA4C LIMK1 LIMK1 CXCL12 CXCL12 PIK3R1 PIK3R1 CCDC125 CCDC125 TRPC7 TRPC7 PPP3CB PPP3CB RASA1 RASA1 LRRC4 LRRC4 PPP3R1 PPP3R1 EFNA5 EFNA5 SMO SMO SEMA4F SEMA4F ABLIM3 ABLIM3 MAPK3 MAPK3 ABLIM1 ABLIM1 SEMA4G SEMA4G NTN3 NTN3 GDF7 GDF7 CAMK2G CAMK2G SLIT1 SLIT1 UNC5B UNC5B DPYSL5 DPYSL5 ARSI ARSI MET MET FZD3 FZD3 PPP3CC PPP3CC UNC5A UNC5A PTPN11 PTPN11 ARHGEF12 ARHGEF12 EFNB2 EFNB2 CXCR4 CXCR4 SLIT3 SLIT3 ROCK2 ROCK2 CFL2 CFL2 LDAH LDAH SEMA3G SEMA3G CAMK2A CAMK2A TRPC6 TRPC6 ROBO3 ROBO3 SEMA7A SEMA7A FYN FYN PAK6 PAK6 NFATC4 NFATC4 EPHA1 EPHA1 CDK5 CDK5 RAF1 RAF1 SRGAP3 SRGAP3 EPHB3 EPHB3 WNT5A WNT5A PLXNA1 PLXNA1 SEMA5B SEMA5B EFNB3 EFNB3 LOC110584664 LOC110584664 PAK2 PAK2 NTN1 NTN1 BOC BOC LOC110584364 LOC110584364 SEMA4D SEMA4D SEMA6D SEMA6D NEO1 NEO1 EPHA7 EPHA7 EPHB6 EPHB6 PLXNA4 PLXNA4 LOC110582753 LOC110582753 GSK3B GSK3B PIK3CA PIK3CA HRAS HRAS SEMA3A SEMA3A SEMA3D SEMA3D SEMA3C SEMA3C NRAS NRAS LOC110581842 LOC110581842 LOC110581841 LOC110581841 NTNG2 NTNG2 PPP3R2 PPP3R2 ABL1 ABL1 PAK5 PAK5 WNT5B WNT5B KRAS KRAS PTK2 PTK2 NGEF NGEF GNAI3 GNAI3 NTNG1 NTNG1 CSDE1 CSDE1 LOC110578784 LOC110578784 NTN4 NTN4 GNAI1 GNAI1 SEMA3E SEMA3E SEMA6C SEMA6C EPHA3 EPHA3 MAPK1 MAPK1 MYL9 MYL9 SRC SRC RAC2 RAC2 LOC110577639 LOC110577639 PLCG1 PLCG1 LOC110578994 LOC110578994 SEMA3B SEMA3B PLXNB1 PLXNB1 SEMA3F SEMA3F LOC110576827 LOC110576827 EPHA6 EPHA6 SRGAP2 SRGAP2 PLXNB2 PLXNB2 TRPC5 TRPC5 PLXNC1 PLXNC1 NRP1 NRP1 PARD3 PARD3 GNAI2 GNAI2 PAK3 PAK3 CAMK2D CAMK2D DCC DCC PARD6G PARD6G ROCK1 ROCK1 LOC110576828 LOC110576828 CDC42 CDC42 EPHA2 EPHA2 ITGB1 ITGB1 PIK3CD PIK3CD PARD6B PARD6B NFATC2 NFATC2 WNT4 WNT4 PIK3R3 PIK3R3 ILK ILK SSH3 SSH3 RHOD RHOD CFL1 CFL1 EPHB2 EPHB2 LRRC4C LRRC4C PRKCZ PRKCZ LOC110575329 LOC110575329 EPHA8 EPHA8 EFNA4 EFNA4 EPHA10 EPHA10 SEMA4A SEMA4A PIK3R2 PIK3R2 ADAM15 ADAM15 PLXNA2 PLXNA2 FES FES RGMA RGMA EFNA1 EFNA1 UNC5C UNC5C TRPC3 TRPC3 UNC5D UNC5D BMPR1B BMPR1B RRAS RRAS SEMA4B SEMA4B RAC3 RAC3 ROBO1 ROBO1 PPP3CA PPP3CA NCK2 NCK2 SLIT2 SLIT2 RAC1 RAC1 EPHB4 EPHB4 EFNB1 EFNB1 SRGAP1 SRGAP1 PIK3CB PIK3CB NCK1 NCK1 ENAH ENAH ROBO2 ROBO2 PRKCA PRKCA PTCH1 PTCH1 BMP7 BMP7 ERAS ERAS SRMS SRMS TRPC1 TRPC1 RYK RYK PTK6 PTK6 TRPC4 TRPC4 ABLIM2 ABLIM2 MYL5 MYL5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EFNA3ephrin-A3 isoform X1; Belongs to the ephrin family. (232 aa)
EFNA2ephrin-A2. (164 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1200 aa)
RND1Rho-related GTP-binding protein Rho6. (232 aa)
NFATC3Nuclear factor of activated T-cells, cytoplasmic 3 isoform X1. (1075 aa)
LOC110592869Protein phosphatase Slingshot homolog 2-like. (202 aa)
SEMA6Bsemaphorin-6B; Belongs to the semaphorin family. (636 aa)
PAK1Non-specific serine/threonine protein kinase. (544 aa)
LOC110593176Protein phosphatase Slingshot homolog 2-like. (1096 aa)
SEMA5Asemaphorin-5A. (1073 aa)
SEMA6Asemaphorin-6A; Belongs to the semaphorin family. (1030 aa)
EPHA5Ephrin type-A receptor 5 isoform X1. (1039 aa)
PARD6APartitioning defective 6 homolog alpha isoform X1. (346 aa)
CAMK2BCalcium/calmodulin-dependent protein kinase type II subunit beta. (651 aa)
LIMK2LIM domain kinase 2 isoform X1. (631 aa)
SSH1Protein phosphatase Slingshot homolog 1. (1013 aa)
EPHA4Ephrin type-A receptor 4 isoform X1. (986 aa)
PAK4Non-specific serine/threonine protein kinase. (594 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (944 aa)
PDK1Protein-serine/threonine kinase. (436 aa)
SEMA4Csemaphorin-4C; Belongs to the semaphorin family. (833 aa)
LIMK1LIM domain kinase 1. (644 aa)
CXCL12Stromal cell-derived factor 1 isoform X1; Belongs to the intercrine alpha (chemokine CxC) family. (119 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (725 aa)
CCDC125Coiled-coil domain-containing protein 125 isoform X1. (518 aa)
TRPC7Short transient receptor potential channel 7; Belongs to the transient receptor (TC 1.A.4) family. (932 aa)
PPP3CBSerine/threonine-protein phosphatase. (527 aa)
RASA1Ras GTPase-activating protein 1 isoform X1. (1039 aa)
LRRC4Leucine-rich repeat-containing protein 4. (650 aa)
PPP3R1Calcineurin subunit B type 1. (170 aa)
EFNA5ephrin-A5 isoform X1; Belongs to the ephrin family. (228 aa)
SMOSmoothened homolog isoform X1; Belongs to the G-protein coupled receptor Fz/Smo family. (788 aa)
SEMA4FLOW QUALITY PROTEIN: semaphorin-4F; Belongs to the semaphorin family. (668 aa)
ABLIM3Actin-binding LIM protein 3 isoform X3. (650 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
ABLIM1Actin-binding LIM protein 1 isoform X4. (778 aa)
SEMA4Gsemaphorin-4G; Belongs to the semaphorin family. (840 aa)
NTN3Netrin-3. (577 aa)
GDF7Growth/differentiation factor 7. (403 aa)
CAMK2GCalcium/calmodulin-dependent protein kinase type II subunit gamma isoform X1. (606 aa)
SLIT1Slit homolog 1 protein. (1531 aa)
UNC5BNetrin receptor UNC5B isoform X1. (945 aa)
DPYSL5Dihydropyrimidinase-related protein 5. (564 aa)
ARSIArylsulfatase I. (575 aa)
METHepatocyte growth factor receptor. (1382 aa)
FZD3Frizzled-3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
PPP3CCSerine/threonine-protein phosphatase. (525 aa)
UNC5ANetrin receptor UNC5A. (842 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (617 aa)
ARHGEF12Rho guanine nucleotide exchange factor 12 isoform X1. (1543 aa)
EFNB2ephrin-B2 isoform X2; Belongs to the ephrin family. (333 aa)
CXCR4C-X-C chemokine receptor type 4; Belongs to the G-protein coupled receptor 1 family. (353 aa)
SLIT3Slit homolog 3 protein. (1672 aa)
ROCK2Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1391 aa)
CFL2Cofilin-2; Belongs to the actin-binding proteins ADF family. (166 aa)
LDAHLipid droplet-associated hydrolase. (325 aa)
SEMA3Gsemaphorin-3G; Belongs to the semaphorin family. (770 aa)
CAMK2ACalcium/calmodulin-dependent protein kinase type II subunit alpha; Belongs to the protein kinase superfamily. (489 aa)
TRPC6Short transient receptor potential channel 6. (504 aa)
ROBO3Roundabout homolog 3. (1376 aa)
SEMA7Asemaphorin-7A; Belongs to the semaphorin family. (663 aa)
FYNTyrosine-protein kinase. (537 aa)
PAK6Non-specific serine/threonine protein kinase. (681 aa)
NFATC4Nuclear factor of activated T-cells, cytoplasmic 4. (902 aa)
EPHA1Ephrin type-A receptor 1 isoform X1. (976 aa)
CDK5Cyclin-dependent-like kinase 5; Belongs to the protein kinase superfamily. (292 aa)
RAF1RAF proto-oncogene serine/threonine-protein kinase. (648 aa)
SRGAP3SLIT-ROBO Rho GTPase-activating protein 3 isoform X1. (1099 aa)
EPHB3Ephrin type-B receptor 3. (959 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
PLXNA1plexin-A1. (1894 aa)
SEMA5Bsemaphorin-5B. (1089 aa)
EFNB3ephrin-B3; Belongs to the ephrin family. (340 aa)
LOC110584664plexin-B3-like. (88 aa)
PAK2Non-specific serine/threonine protein kinase. (524 aa)
NTN1Netrin-1. (351 aa)
BOCBrother of CDO. (1110 aa)
LOC110584364LOW QUALITY PROTEIN: neural cell adhesion molecule L1-like. (775 aa)
SEMA4Dsemaphorin-4D; Belongs to the semaphorin family. (1042 aa)
SEMA6Dsemaphorin-6D; Belongs to the semaphorin family. (1073 aa)
NEO1Neogenin. (1417 aa)
EPHA7Ephrin type-A receptor 7 isoform X1. (1005 aa)
EPHB6Ephrin type-B receptor 6. (1013 aa)
PLXNA4plexin-A4 isoform X1. (1901 aa)
LOC110582753plexin-A3-like. (224 aa)
GSK3BGlycogen synthase kinase-3 beta isoform X1; Belongs to the protein kinase superfamily. (433 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
HRASGTPase HRas isoform X1. (189 aa)
SEMA3Asemaphorin-3A; Belongs to the semaphorin family. (772 aa)
SEMA3Dsemaphorin-3D isoform X1; Belongs to the semaphorin family. (777 aa)
SEMA3Csemaphorin-3C; Belongs to the semaphorin family. (692 aa)
NRASGTPase NRas. (189 aa)
LOC110581842Regulator of G-protein signaling 3-like isoform X1. (602 aa)
LOC110581841Regulator of G-protein signaling 3-like isoform X1. (505 aa)
NTNG2netrin-G2 isoform X1. (565 aa)
PPP3R2Calcineurin subunit B type 2. (170 aa)
ABL1Tyrosine-protein kinase. (1137 aa)
PAK5Non-specific serine/threonine protein kinase. (719 aa)
WNT5BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (358 aa)
KRASGTPase KRas. (188 aa)
PTK2Focal adhesion kinase 1 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1055 aa)
NGEFEphexin-1. (592 aa)
GNAI3Guanine nucleotide-binding protein G(K) subunit alpha. (354 aa)
NTNG1netrin-G1. (539 aa)
CSDE1Cold shock domain-containing protein E1 isoform X1. (798 aa)
LOC110578784LOW QUALITY PROTEIN: plexin-A3-like. (969 aa)
NTN4Netrin-4 isoform X2. (628 aa)
GNAI1Guanine nucleotide-binding protein G(I) subunit alpha-1. (354 aa)
SEMA3Esemaphorin-3E; Belongs to the semaphorin family. (715 aa)
SEMA6Csemaphorin-6C isoform X1; Belongs to the semaphorin family. (963 aa)
EPHA3Ephrin type-A receptor 3 isoform X1. (984 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (361 aa)
MYL9Myosin regulatory light polypeptide 9. (172 aa)
SRCTyrosine-protein kinase. (536 aa)
RAC2Ras-related C3 botulinum toxin substrate 2 isoform X1. (192 aa)
LOC110577639plexin-B3-like. (606 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1289 aa)
LOC110578994Neural cell adhesion molecule L1-like. (133 aa)
SEMA3Bsemaphorin-3B; Belongs to the semaphorin family. (748 aa)
PLXNB1plexin-B1 isoform X1. (2137 aa)
SEMA3Fsemaphorin-3F isoform X1; Belongs to the semaphorin family. (790 aa)
LOC110576827Myosin regulatory light chain 12B. (172 aa)
EPHA6Ephrin type-A receptor 6. (1130 aa)
SRGAP2SLIT-ROBO Rho GTPase-activating protein 2 isoform X1. (1071 aa)
PLXNB2plexin-B2. (1585 aa)
TRPC5Short transient receptor potential channel 5; Belongs to the transient receptor (TC 1.A.4) family. (748 aa)
PLXNC1plexin-C1. (1576 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (923 aa)
PARD3Partitioning defective 3 homolog isoform X1. (1359 aa)
GNAI2Guanine nucleotide-binding protein G(I) subunit alpha-2. (355 aa)
PAK3Non-specific serine/threonine protein kinase. (544 aa)
CAMK2DCalcium/calmodulin-dependent protein kinase type II subunit delta isoform X4. (525 aa)
DCCNetrin receptor DCC. (1417 aa)
PARD6GPartitioning defective 6 homolog gamma. (363 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1354 aa)
LOC110576828Myosin regulatory light polypeptide 9. (172 aa)
CDC42Cell division control protein 42 homolog. (191 aa)
EPHA2Ephrin type-A receptor 2. (975 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (798 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa)
PARD6BPartitioning defective 6 homolog beta. (370 aa)
NFATC2Nuclear factor of activated T-cells, cytoplasmic 2. (920 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (424 aa)
PIK3R3Phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1. (507 aa)
ILKIntegrin-linked protein kinase isoform X1. (452 aa)
SSH3Protein phosphatase Slingshot homolog 3. (650 aa)
RHODRho-related GTP-binding protein RhoD isoform X1. (210 aa)
CFL1Cofilin-1; Belongs to the actin-binding proteins ADF family. (219 aa)
EPHB2Ephrin type-B receptor 2. (963 aa)
LRRC4CLeucine-rich repeat-containing protein 4C. (640 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (591 aa)
LOC110575329Tyrosine-protein phosphatase non-receptor type 11-like. (582 aa)
EPHA8Ephrin type-A receptor 8. (991 aa)
EFNA4ephrin-A4; Belongs to the ephrin family. (204 aa)
EPHA10Ephrin type-A receptor 10. (1008 aa)
SEMA4Asemaphorin-4A; Belongs to the semaphorin family. (708 aa)
PIK3R2Phosphatidylinositol 3-kinase regulatory subunit beta isoform X1. (726 aa)
ADAM15Disintegrin and metalloproteinase domain-containing protein 15 isoform X1. (893 aa)
PLXNA2plexin-A2. (1894 aa)
FESTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (820 aa)
RGMARepulsive guidance molecule A isoform X1. (459 aa)
EFNA1ephrin-A1; Belongs to the ephrin family. (205 aa)
UNC5CNetrin receptor UNC5C. (931 aa)
TRPC3Short transient receptor potential channel 3 isoform X1; Belongs to the transient receptor (TC 1.A.4) family. (921 aa)
UNC5DNetrin receptor UNC5D. (953 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
RRASRas-related protein R-Ras isoform X1. (218 aa)
SEMA4Bsemaphorin-4B isoform X1; Belongs to the semaphorin family. (858 aa)
RAC3Ras-related C3 botulinum toxin substrate 3. (195 aa)
ROBO1Roundabout homolog 1 isoform X1. (1615 aa)
PPP3CASerine/threonine-protein phosphatase. (526 aa)
NCK2Cytoplasmic protein. (380 aa)
SLIT2Slit homolog 2 protein isoform X3. (1534 aa)
RAC1Ras-related C3 botulinum toxin substrate 1 isoform X1. (211 aa)
EPHB4Ephrin type-B receptor 4. (988 aa)
EFNB1ephrin-B1; Belongs to the ephrin family. (346 aa)
SRGAP1SLIT-ROBO Rho GTPase-activating protein 1 isoform X1. (1085 aa)
PIK3CBLOW QUALITY PROTEIN: phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform; Belongs to the PI3/PI4-kinase family. (1070 aa)
NCK1Cytoplasmic protein. (377 aa)
ENAHProtein enabled homolog. (458 aa)
ROBO2Roundabout homolog 2. (1376 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
PTCH1Protein patched homolog 1. (1301 aa)
BMP7Bone morphogenetic protein 7. (431 aa)
ERASGTPase ERas. (233 aa)
SRMSTyrosine-protein kinase. (493 aa)
TRPC1Short transient receptor potential channel 1 isoform X1; Belongs to the transient receptor (TC 1.A.4) family. (794 aa)
RYKTyrosine-protein kinase RYK. (596 aa)
PTK6Tyrosine-protein kinase. (486 aa)
TRPC4Short transient receptor potential channel 4; Belongs to the transient receptor (TC 1.A.4) family. (977 aa)
ABLIM2Actin-binding LIM protein 2 isoform X1. (494 aa)
MYL5Myosin light chain 5. (189 aa)
Your Current Organism:
Neomonachus schauinslandi
NCBI taxonomy Id: 29088
Other names: Hawaiian monk seal, Monachus schauinslandi, N. schauinslandi
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