STRINGSTRING
PTPN6 PTPN6 PIK3R2 PIK3R2 IKBKG IKBKG AKT3 AKT3 LOC110573700 LOC110573700 GRB2 GRB2 IKBKB IKBKB DAPP1 DAPP1 NFKB1 NFKB1 AKT1 AKT1 RAC3 RAC3 PPP3CA PPP3CA RAC1 RAC1 PIK3CB PIK3CB FOS FOS CD79B CD79B INPP5D INPP5D ERAS ERAS VAV1 VAV1 PLCG2 PLCG2 INPPL1 INPPL1 NFATC3 NFATC3 MAP2K2 MAP2K2 AKT2 AKT2 NFKBIB NFKBIB CD19 CD19 PIK3R1 PIK3R1 PPP3CB PPP3CB PPP3R1 PPP3R1 SOS2 SOS2 CD22 CD22 MAPK3 MAPK3 BLNK BLNK CHUK CHUK PIK3AP1 PIK3AP1 SOS1 SOS1 PPP3CC PPP3CC FCGR2B FCGR2B BTK BTK NFKBIA NFKBIA RASGRP3 RASGRP3 SYK SYK RAF1 RAF1 CD79A CD79A MAP2K1 MAP2K1 NFKBIE NFKBIE CD72 CD72 VAV2 VAV2 GSK3B GSK3B PIK3CA PIK3CA HRAS HRAS BCL10 BCL10 NRAS NRAS PPP3R2 PPP3R2 KRAS KRAS VAV3 VAV3 CSDE1 CSDE1 MAPK1 MAPK1 RAC2 RAC2 PRKCB PRKCB CARD11 CARD11 LYN LYN LOC110578350 LOC110578350 NFATC1 NFATC1 MALT1 MALT1 PIK3CD PIK3CD NFATC2 NFATC2 PIK3R3 PIK3R3 CD81 CD81 RELA RELA JUN JUN LOC110573761 LOC110573761
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (595 aa)
PIK3R2Phosphatidylinositol 3-kinase regulatory subunit beta isoform X1. (726 aa)
IKBKGNF-kappa-B essential modulator. (419 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
LOC110573700Leukocyte immunoglobulin-like receptor subfamily B member 3. (571 aa)
GRB2Growth factor receptor-bound protein 2. (217 aa)
IKBKBInhibitor of nuclear factor kappa-B kinase subunit beta. (756 aa)
DAPP1Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide. (280 aa)
NFKB1Nuclear factor NF-kappa-B p105 subunit isoform X4. (987 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
RAC3Ras-related C3 botulinum toxin substrate 3. (195 aa)
PPP3CASerine/threonine-protein phosphatase. (526 aa)
RAC1Ras-related C3 botulinum toxin substrate 1 isoform X1. (211 aa)
PIK3CBLOW QUALITY PROTEIN: phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform; Belongs to the PI3/PI4-kinase family. (1070 aa)
FOSProto-oncogene c-Fos. (380 aa)
CD79BB-cell antigen receptor complex-associated protein beta chain. (222 aa)
INPP5DPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1. (1160 aa)
ERASGTPase ERas. (233 aa)
VAV1Proto-oncogene vav isoform X1. (845 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1200 aa)
INPPL1Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2. (1264 aa)
NFATC3Nuclear factor of activated T-cells, cytoplasmic 3 isoform X1. (1075 aa)
MAP2K2Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
NFKBIBNF-kappa-B inhibitor beta isoform X1. (354 aa)
CD19B-lymphocyte antigen CD19. (560 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (725 aa)
PPP3CBSerine/threonine-protein phosphatase. (527 aa)
PPP3R1Calcineurin subunit B type 1. (170 aa)
SOS2Son of sevenless homolog 2 isoform X1. (1338 aa)
CD22B-cell receptor CD22 isoform X1. (845 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
BLNKB-cell linker protein. (418 aa)
CHUKInhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1. (744 aa)
PIK3AP1Phosphoinositide 3-kinase adapter protein 1 isoform X1. (811 aa)
SOS1Son of sevenless homolog 1. (1333 aa)
PPP3CCSerine/threonine-protein phosphatase. (525 aa)
FCGR2BLow affinity immunoglobulin gamma Fc region receptor II-b. (295 aa)
BTKTyrosine-protein kinase. (659 aa)
NFKBIANF-kappa-B inhibitor alpha. (314 aa)
RASGRP3Ras guanyl-releasing protein 3. (693 aa)
SYKTyrosine-protein kinase. (635 aa)
RAF1RAF proto-oncogene serine/threonine-protein kinase. (648 aa)
CD79AB-cell antigen receptor complex-associated protein alpha chain. (236 aa)
MAP2K1Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
NFKBIENF-kappa-B inhibitor epsilon. (361 aa)
CD72B-cell differentiation antigen CD72. (304 aa)
VAV2Guanine nucleotide exchange factor VAV2. (862 aa)
GSK3BGlycogen synthase kinase-3 beta isoform X1; Belongs to the protein kinase superfamily. (433 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
HRASGTPase HRas isoform X1. (189 aa)
BCL10B-cell lymphoma/leukemia 10 isoform X1. (233 aa)
NRASGTPase NRas. (189 aa)
PPP3R2Calcineurin subunit B type 2. (170 aa)
KRASGTPase KRas. (188 aa)
VAV3Guanine nucleotide exchange factor VAV3. (847 aa)
CSDE1Cold shock domain-containing protein E1 isoform X1. (798 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (361 aa)
RAC2Ras-related C3 botulinum toxin substrate 2 isoform X1. (192 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (634 aa)
CARD11Caspase recruitment domain-containing protein 11. (455 aa)
LYNTyrosine-protein kinase. (512 aa)
LOC110578350Leukocyte immunoglobulin-like receptor subfamily A member 6. (226 aa)
NFATC1Nuclear factor of activated T-cells, cytoplasmic 1 isoform X1. (891 aa)
MALT1Mucosa-associated lymphoid tissue lymphoma translocation protein 1. (839 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa)
NFATC2Nuclear factor of activated T-cells, cytoplasmic 2. (920 aa)
PIK3R3Phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1. (507 aa)
CD81Tetraspanin. (165 aa)
RELATranscription factor p65. (531 aa)
JUNTranscription factor AP-1 isoform X1; Belongs to the bZIP family. (335 aa)
LOC110573761Leukocyte immunoglobulin-like receptor subfamily B member 3 isoform X1. (510 aa)
Your Current Organism:
Neomonachus schauinslandi
NCBI taxonomy Id: 29088
Other names: Hawaiian monk seal, Monachus schauinslandi, N. schauinslandi
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