STRINGSTRING
NOS1AP NOS1AP GNG14 GNG14 GNG7 GNG7 ADCY1 ADCY1 ADCY6 ADCY6 ADCY7 ADCY7 GNGT2 GNGT2 CACNA1G CACNA1G CAMK2B CAMK2B LOC110592210 LOC110592210 KCNJ3 KCNJ3 CREB1 CREB1 LOC110592156 LOC110592156 ADCY2 ADCY2 PRKG2 PRKG2 GNG2 GNG2 RYR1 RYR1 MAPK3 MAPK3 GUCY1B3 GUCY1B3 NOS1 NOS1 ADCY9 ADCY9 CAMK2G CAMK2G PTRHD1 PTRHD1 CACNA1H CACNA1H ARSI ARSI GRIA2 GRIA2 GUCY1A3 GUCY1A3 FBXO21 FBXO21 PRKG1 PRKG1 GNG13 GNG13 GRIN2A GRIN2A RYR3 RYR3 ADCY3 ADCY3 GNAO1 GNAO1 GRIA1 GRIA1 CAMK2A CAMK2A LOC110586587 LOC110586587 CALML5 CALML5 GUCY1A2 GUCY1A2 KCNJ5 KCNJ5 GRIA4 GRIA4 MTNR1A MTNR1A RYR2 RYR2 GNG4 GNG4 CALML4 CALML4 ADCY4 ADCY4 PLCB2 PLCB2 ITPR1 ITPR1 CACNA1D CACNA1D PER1 PER1 RASD1 RASD1 GNB5 GNB5 GRIN1 GRIN1 PRKACB PRKACB ADCY5 ADCY5 GNB4 GNB4 GNG5 GNG5 LOC110582045 LOC110582045 LOC110581983 LOC110581983 LOC110581981 LOC110581981 LOC110581982 LOC110581982 GNGT1 GNGT1 GNG11 GNG11 GNG10 GNG10 PLCB1 PLCB1 ADCY8 ADCY8 GNB3 GNB3 CACNA1C CACNA1C GRIN2B GRIN2B GNAI3 GNAI3 ADCYAP1R1 ADCYAP1R1 GNAI1 GNAI1 LOC110579802 LOC110579802 MAPK1 MAPK1 PLCB4 PLCB4 PRKCB PRKCB CACNA1I CACNA1I GRIA3 GRIA3 GNG3 GNG3 GNAI2 GNAI2 CAMK2D CAMK2D ADCYAP1 ADCYAP1 PER3 PER3 GNB1 GNB1 PLCB3 PLCB3 CALML6 CALML6 PRKCG PRKCG KCNJ9 KCNJ9 GRIN2D GRIN2D ADCY10 ADCY10 GRIN2C GRIN2C GNG12 GNG12 GNG8 GNG8 LOC110572425 LOC110572425 GNB2 GNB2 CALM1 CALM1 FOS FOS RPS6KA5 RPS6KA5 PRKCA PRKCA MTNR1B MTNR1B PER2 PER2 KCNJ6 KCNJ6 LOC110569839 LOC110569839 GNAS GNAS PRKACA PRKACA
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
NOS1APCarboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein isoform X1. (500 aa)
GNG14LOW QUALITY PROTEIN: uncharacterized LOC105372280 homolog. (100 aa)
GNG7Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
ADCY1Adenylate cyclase type 1. (921 aa)
ADCY6Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1161 aa)
ADCY7Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1075 aa)
GNGT2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (118 aa)
CACNA1GVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2379 aa)
CAMK2BCalcium/calmodulin-dependent protein kinase type II subunit beta. (651 aa)
LOC110592210Calmodulin-like; Belongs to the calmodulin family. (149 aa)
KCNJ3LOW QUALITY PROTEIN: G protein-activated inward rectifier potassium channel 1. (501 aa)
CREB1Cyclic AMP-responsive element-binding protein 1. (327 aa)
LOC110592156Calmodulin-like; Belongs to the calmodulin family. (98 aa)
ADCY2Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1091 aa)
PRKG2cGMP-dependent protein kinase. (762 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (71 aa)
RYR1Ryanodine receptor 1. (4995 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
GUCY1B3Guanylate cyclase soluble subunit beta-1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (637 aa)
NOS1Nitric oxide synthase, brain isoform X1. (1467 aa)
ADCY9Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1352 aa)
CAMK2GCalcium/calmodulin-dependent protein kinase type II subunit gamma isoform X1. (606 aa)
PTRHD1Putative peptidyl-tRNA hydrolase PTRHD1. (140 aa)
CACNA1HVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2301 aa)
ARSIArylsulfatase I. (575 aa)
GRIA2Glutamate receptor 2 isoform X1. (940 aa)
GUCY1A3Guanylate cyclase soluble subunit alpha-3; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (690 aa)
FBXO21F-box only protein 21 isoform X1. (627 aa)
PRKG1cGMP-dependent protein kinase. (726 aa)
GNG13Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13. (67 aa)
GRIN2AGlutamate receptor ionotropic, NMDA 2A. (1464 aa)
RYR3Ryanodine receptor 3. (4777 aa)
ADCY3Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1145 aa)
GNAO1Guanine nucleotide-binding protein G(O) subunit alpha. (354 aa)
GRIA1Glutamate receptor 1 isoform X1. (906 aa)
CAMK2ACalcium/calmodulin-dependent protein kinase type II subunit alpha; Belongs to the protein kinase superfamily. (489 aa)
LOC110586587Calmodulin-like protein 3; Belongs to the calmodulin family. (149 aa)
CALML5Calmodulin-like protein 5. (149 aa)
GUCY1A2Guanylate cyclase soluble subunit alpha-2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (673 aa)
KCNJ5G protein-activated inward rectifier potassium channel 4. (419 aa)
GRIA4Glutamate receptor 4 isoform X2. (902 aa)
MTNR1ALOW QUALITY PROTEIN: melatonin receptor type 1A; Belongs to the G-protein coupled receptor 1 family. (364 aa)
RYR2Ryanodine receptor 2. (5000 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
CALML4LOW QUALITY PROTEIN: calmodulin-like protein 4. (197 aa)
ADCY4Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1186 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1 isoform X1. (2709 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2181 aa)
PER1Period circadian protein homolog 1 isoform X1. (1321 aa)
RASD1Dexamethasone-induced Ras-related protein 1. (279 aa)
GNB5Guanine nucleotide-binding protein subunit beta-5. (395 aa)
GRIN1Glutamate receptor ionotropic, NMDA 1 isoform X1. (943 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta; Belongs to the protein kinase superfamily. (397 aa)
ADCY5Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1205 aa)
GNB4Guanine nucleotide-binding protein subunit beta-4. (340 aa)
GNG5Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
LOC110582045Uncharacterized protein LOC110582045. (205 aa)
LOC110581983Adenylate cyclase type 10-like. (162 aa)
LOC110581981Adenylate cyclase type 10-like. (131 aa)
LOC110581982Adenylate cyclase type 10-like. (313 aa)
GNGT1Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
GNG11Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
GNG10Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
ADCY8Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1250 aa)
GNB3Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3. (340 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2191 aa)
GRIN2BGlutamate receptor ionotropic, NMDA 2B. (1484 aa)
GNAI3Guanine nucleotide-binding protein G(K) subunit alpha. (354 aa)
ADCYAP1R1Pituitary adenylate cyclase-activating polypeptide type I receptor isoform X3; Belongs to the G-protein coupled receptor 2 family. (497 aa)
GNAI1Guanine nucleotide-binding protein G(I) subunit alpha-1. (354 aa)
LOC110579802LOW QUALITY PROTEIN: guanylate cyclase soluble subunit beta-2-like; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (646 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (361 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1194 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (634 aa)
CACNA1IVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2187 aa)
GRIA3Glutamate receptor 3. (894 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
GNAI2Guanine nucleotide-binding protein G(I) subunit alpha-2. (355 aa)
CAMK2DCalcium/calmodulin-dependent protein kinase type II subunit delta isoform X4. (525 aa)
ADCYAP1Pituitary adenylate cyclase-activating polypeptide. (176 aa)
PER3Period circadian protein homolog 3 isoform X1. (1124 aa)
GNB1Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1. (340 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1230 aa)
CALML6Calmodulin-like protein 6. (232 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
KCNJ9G protein-activated inward rectifier potassium channel 3. (392 aa)
GRIN2DGlutamate receptor ionotropic, NMDA 2D. (930 aa)
ADCY10Adenylate cyclase type 10 isoform X1. (1610 aa)
GRIN2CGlutamate receptor ionotropic, NMDA 2C isoform X2. (1227 aa)
GNG12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
GNG8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
LOC110572425Parvalbumin beta-like. (129 aa)
GNB2Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2. (340 aa)
CALM1Calmodulin-1; Belongs to the calmodulin family. (149 aa)
FOSProto-oncogene c-Fos. (380 aa)
RPS6KA5Ribosomal protein S6 kinase. (798 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
MTNR1BLOW QUALITY PROTEIN: melatonin receptor type 1B. (353 aa)
PER2Period circadian protein homolog 2. (1277 aa)
KCNJ6G protein-activated inward rectifier potassium channel 2. (456 aa)
LOC110569839Neuroendocrine secretory protein 55. (246 aa)
GNASGuanine nucleotide-binding protein G(S) subunit alpha isoforms XLas isoform X1. (1003 aa)
PRKACAcAMP-dependent protein kinase catalytic subunit alpha; Belongs to the protein kinase superfamily. (351 aa)
Your Current Organism:
Neomonachus schauinslandi
NCBI taxonomy Id: 29088
Other names: Hawaiian monk seal, Monachus schauinslandi, N. schauinslandi
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