STRINGSTRING
HOMER2 HOMER2 SLC17A7 SLC17A7 GRIN2C GRIN2C GRIN2D GRIN2D SHANK1 SHANK1 GLUL GLUL PLA2G4A PLA2G4A HOMER3 HOMER3 SLC1A6 SLC1A6 PRKCG PRKCG SLC1A7 SLC1A7 ITPR3 ITPR3 SLC1A2 SLC1A2 PLCB3 PLCB3 GRIK3 GRIK3 GRK2 GRK2 GNB1 GNB1 SHANK2 SHANK2 SLC17A6 SLC17A6 GRM4 GRM4 GNAI2 GNAI2 GNG3 GNG3 SLC38A3 SLC38A3 GRIA3 GRIA3 SHANK3 SHANK3 GLS2 GLS2 PRKCB PRKCB PLCB4 PLCB4 SLC17A8 SLC17A8 MAPK1 MAPK1 GNAI1 GNAI1 GRM3 GRM3 GNAI3 GNAI3 GRIN2B GRIN2B ITPR2 ITPR2 CACNA1C CACNA1C GNB3 GNB3 ADCY8 ADCY8 PLCB1 PLCB1 GNG10 GNG10 GRIN3A GRIN3A PPP3R2 PPP3R2 GNG11 GNG11 GNGT1 GNGT1 GNG5 GNG5 GNB4 GNB4 ADCY5 ADCY5 PRKACB PRKACB GRM6 GRM6 GRIN1 GRIN1 GRM1 GRM1 GNB5 GNB5 LGSN LGSN DLG4 DLG4 GRIK5 GRIK5 GRM7 GRM7 CACNA1D CACNA1D ITPR1 ITPR1 PLCB2 PLCB2 JMJD7 JMJD7 PLA2G4F PLA2G4F PLA2G4B PLA2G4B PLA2G4D PLA2G4D ADCY4 ADCY4 GRIK2 GRIK2 GNG4 GNG4 SLC1A3 SLC1A3 GRIK4 GRIK4 SLC1A1 SLC1A1 GRIA4 GRIA4 PLD2 PLD2 GRM2 GRM2 GRIA1 GRIA1 ADCY3 ADCY3 PLA2G4E PLA2G4E GRIN2A GRIN2A GNG13 GNG13 PPP3CC PPP3CC GRIA2 GRIA2 PTRHD1 PTRHD1 HOMER1 HOMER1 ADCY9 ADCY9 MAPK3 MAPK3 GRM8 GRM8 PPP3R1 PPP3R1 GNG2 GNG2 PPP3CB PPP3CB ADCY2 ADCY2 PLD1 PLD1 KCNJ3 KCNJ3 GRK3 GRK3 GNGT2 GNGT2 GLS GLS ADCY7 ADCY7 SLC38A1 SLC38A1 ADCY6 ADCY6 CACNA1A CACNA1A ADCY1 ADCY1 PRKACA PRKACA GNAO1 GNAO1 SLC38A2 SLC38A2 GNG7 GNG7 GRIN3B GRIN3B GNG14 GNG14 GNAS GNAS LOC110569839 LOC110569839 GRIK1 GRIK1 TRPC1 TRPC1 GRM5 GRM5 PRKCA PRKCA GNB2 GNB2 PPP3CA PPP3CA GNG8 GNG8 GNG12 GNG12
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HOMER2Homer protein homolog 2. (279 aa)
SLC17A7Vesicular glutamate transporter 1. (560 aa)
GRIN2CGlutamate receptor ionotropic, NMDA 2C isoform X2. (1227 aa)
GRIN2DGlutamate receptor ionotropic, NMDA 2D. (930 aa)
SHANK1SH3 and multiple ankyrin repeat domains protein 1. (2085 aa)
GLULGlutamine synthetase. (413 aa)
PLA2G4APhospholipase A2. (733 aa)
HOMER3Homer protein homolog 3 isoform X1. (323 aa)
SLC1A6Amino acid transporter. (312 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
SLC1A7Amino acid transporter. (574 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2584 aa)
SLC1A2Amino acid transporter. (565 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1230 aa)
GRIK3Glutamate receptor ionotropic, kainate 3 isoform X1. (919 aa)
GRK2G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (647 aa)
GNB1Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1. (340 aa)
SHANK2SH3 and multiple ankyrin repeat domains protein 2. (1800 aa)
SLC17A6Vesicular glutamate transporter 2. (582 aa)
GRM4Metabotropic glutamate receptor 4 isoform X1. (912 aa)
GNAI2Guanine nucleotide-binding protein G(I) subunit alpha-2. (355 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
SLC38A3Sodium-coupled neutral amino acid transporter 3. (504 aa)
GRIA3Glutamate receptor 3. (894 aa)
SHANK3LOW QUALITY PROTEIN: SH3 and multiple ankyrin repeat domains protein 3. (1622 aa)
GLS2Glutaminase liver isoform, mitochondrial isoform X1. (602 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (634 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1194 aa)
SLC17A8Vesicular glutamate transporter 3 isoform X1. (589 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (361 aa)
GNAI1Guanine nucleotide-binding protein G(I) subunit alpha-1. (354 aa)
GRM3Metabotropic glutamate receptor 3. (879 aa)
GNAI3Guanine nucleotide-binding protein G(K) subunit alpha. (354 aa)
GRIN2BGlutamate receptor ionotropic, NMDA 2B. (1484 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2701 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2191 aa)
GNB3Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3. (340 aa)
ADCY8Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1250 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
GNG10Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
GRIN3AGlutamate receptor ionotropic, NMDA 3A; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1115 aa)
PPP3R2Calcineurin subunit B type 2. (170 aa)
GNG11Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
GNGT1Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
GNG5Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
GNB4Guanine nucleotide-binding protein subunit beta-4. (340 aa)
ADCY5Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1205 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta; Belongs to the protein kinase superfamily. (397 aa)
GRM6Metabotropic glutamate receptor 6. (881 aa)
GRIN1Glutamate receptor ionotropic, NMDA 1 isoform X1. (943 aa)
GRM1Metabotropic glutamate receptor 1 isoform X1. (1190 aa)
GNB5Guanine nucleotide-binding protein subunit beta-5. (395 aa)
LGSNLengsin; Belongs to the glutamine synthetase family. (574 aa)
DLG4Disks large homolog 4 isoform X2; Belongs to the MAGUK family. (766 aa)
GRIK5Glutamate receptor ionotropic, kainate 5 isoform X1. (981 aa)
GRM7LOW QUALITY PROTEIN: metabotropic glutamate receptor 7. (922 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2181 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1 isoform X1. (2709 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1186 aa)
JMJD7jmjC domain-containing protein 7. (316 aa)
PLA2G4FPhospholipase A2. (860 aa)
PLA2G4BPhospholipase A2. (782 aa)
PLA2G4DPhospholipase A2. (817 aa)
ADCY4Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
GRIK2Glutamate receptor ionotropic, kainate 2 isoform X1. (908 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
SLC1A3Amino acid transporter. (542 aa)
GRIK4Glutamate receptor ionotropic, kainate 4. (956 aa)
SLC1A1Amino acid transporter. (524 aa)
GRIA4Glutamate receptor 4 isoform X2. (902 aa)
PLD2Phospholipase. (933 aa)
GRM2Metabotropic glutamate receptor 2. (871 aa)
GRIA1Glutamate receptor 1 isoform X1. (906 aa)
ADCY3Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1145 aa)
PLA2G4EPhospholipase A2. (841 aa)
GRIN2AGlutamate receptor ionotropic, NMDA 2A. (1464 aa)
GNG13Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13. (67 aa)
PPP3CCSerine/threonine-protein phosphatase. (525 aa)
GRIA2Glutamate receptor 2 isoform X1. (940 aa)
PTRHD1Putative peptidyl-tRNA hydrolase PTRHD1. (140 aa)
HOMER1Homer protein homolog 1. (354 aa)
ADCY9Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1352 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
GRM8Metabotropic glutamate receptor 8 isoform X1. (908 aa)
PPP3R1Calcineurin subunit B type 1. (170 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (71 aa)
PPP3CBSerine/threonine-protein phosphatase. (527 aa)
ADCY2Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1091 aa)
PLD1Phospholipase. (1040 aa)
KCNJ3LOW QUALITY PROTEIN: G protein-activated inward rectifier potassium channel 1. (501 aa)
GRK3G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (665 aa)
GNGT2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (118 aa)
GLSGlutaminase kidney isoform, mitochondrial isoform X1. (672 aa)
ADCY7Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1075 aa)
SLC38A1Sodium-coupled neutral amino acid transporter 1. (487 aa)
ADCY6Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1161 aa)
CACNA1AVoltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents. (2504 aa)
ADCY1Adenylate cyclase type 1. (921 aa)
PRKACAcAMP-dependent protein kinase catalytic subunit alpha; Belongs to the protein kinase superfamily. (351 aa)
GNAO1Guanine nucleotide-binding protein G(O) subunit alpha. (354 aa)
SLC38A2Sodium-coupled neutral amino acid transporter 2 isoform X1. (506 aa)
GNG7Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
GRIN3BGlutamate receptor ionotropic, NMDA 3B; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (910 aa)
GNG14LOW QUALITY PROTEIN: uncharacterized LOC105372280 homolog. (100 aa)
GNASGuanine nucleotide-binding protein G(S) subunit alpha isoforms XLas isoform X1. (1003 aa)
LOC110569839Neuroendocrine secretory protein 55. (246 aa)
GRIK1LOW QUALITY PROTEIN: glutamate receptor ionotropic, kainate 1. (920 aa)
TRPC1Short transient receptor potential channel 1 isoform X1; Belongs to the transient receptor (TC 1.A.4) family. (794 aa)
GRM5Metabotropic glutamate receptor 5. (1005 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
GNB2Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2. (340 aa)
PPP3CASerine/threonine-protein phosphatase. (526 aa)
GNG8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
GNG12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
Your Current Organism:
Neomonachus schauinslandi
NCBI taxonomy Id: 29088
Other names: Hawaiian monk seal, Monachus schauinslandi, N. schauinslandi
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