STRINGSTRING
RYR1 RYR1 GUCY1B3 GUCY1B3 NOS1 NOS1 GRIA2 GRIA2 GUCY1A3 GUCY1A3 FBXO21 FBXO21 PRKG1 PRKG1 PLA2G4E PLA2G4E GRIA1 GRIA1 GUCY1A2 GUCY1A2 PPP2R1B PPP2R1B PLA2G4D PLA2G4D PLA2G4B PLA2G4B PLA2G4F PLA2G4F JMJD7 JMJD7 PLCB2 PLCB2 RAF1 RAF1 ITPR1 ITPR1 PPP2CB PPP2CB MAP2K1 MAP2K1 GRM1 GRM1 BRAF BRAF HRAS HRAS NRAS NRAS PLCB1 PLCB1 LOC110579709 LOC110579709 ITPR2 ITPR2 KRAS KRAS GNAI3 GNAI3 GNAZ GNAZ CSDE1 CSDE1 PPP1R17 PPP1R17 IGF1 IGF1 GNAI1 GNAI1 LOC110579802 LOC110579802 MAPK1 MAPK1 PLCB4 PLCB4 PRKCB PRKCB CRH CRH LYN LYN GRIA3 GRIA3 GNAI2 GNAI2 PLCB3 PLCB3 ITPR3 ITPR3 PRKCG PRKCG PLA2G4A PLA2G4A GNA12 GNA12 PPP2R1A PPP2R1A IGF1R IGF1R ARAF ARAF GRID2 GRID2 PRKCA PRKCA ERAS ERAS LOC110570357 LOC110570357 GNA13 GNA13 LOC110569839 LOC110569839 GNAS GNAS GNA11 GNA11 GNAO1 GNAO1 CACNA1A CACNA1A MAP2K2 MAP2K2 PPP2CA PPP2CA PRKG2 PRKG2 MAPK3 MAPK3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RYR1Ryanodine receptor 1. (4995 aa)
GUCY1B3Guanylate cyclase soluble subunit beta-1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (637 aa)
NOS1Nitric oxide synthase, brain isoform X1. (1467 aa)
GRIA2Glutamate receptor 2 isoform X1. (940 aa)
GUCY1A3Guanylate cyclase soluble subunit alpha-3; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (690 aa)
FBXO21F-box only protein 21 isoform X1. (627 aa)
PRKG1cGMP-dependent protein kinase. (726 aa)
PLA2G4EPhospholipase A2. (841 aa)
GRIA1Glutamate receptor 1 isoform X1. (906 aa)
GUCY1A2Guanylate cyclase soluble subunit alpha-2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (673 aa)
PPP2R1BSerine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform isoform X2. (693 aa)
PLA2G4DPhospholipase A2. (817 aa)
PLA2G4BPhospholipase A2. (782 aa)
PLA2G4FPhospholipase A2. (860 aa)
JMJD7jmjC domain-containing protein 7. (316 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1186 aa)
RAF1RAF proto-oncogene serine/threonine-protein kinase. (648 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1 isoform X1. (2709 aa)
PPP2CBSerine/threonine-protein phosphatase. (309 aa)
MAP2K1Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
GRM1Metabotropic glutamate receptor 1 isoform X1. (1190 aa)
BRAFSerine/threonine-protein kinase B-raf. (764 aa)
HRASGTPase HRas isoform X1. (189 aa)
NRASGTPase NRas. (189 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
LOC110579709Guanine nucleotide-binding protein G(Q) subunit alpha. (301 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2701 aa)
KRASGTPase KRas. (188 aa)
GNAI3Guanine nucleotide-binding protein G(K) subunit alpha. (354 aa)
GNAZGuanine nucleotide-binding protein G(Z) subunit alpha. (355 aa)
CSDE1Cold shock domain-containing protein E1 isoform X1. (798 aa)
PPP1R17Protein phosphatase 1 regulatory subunit 17. (155 aa)
IGF1Insulin-like growth factor I isoform X1. (185 aa)
GNAI1Guanine nucleotide-binding protein G(I) subunit alpha-1. (354 aa)
LOC110579802LOW QUALITY PROTEIN: guanylate cyclase soluble subunit beta-2-like; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (646 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (361 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1194 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (634 aa)
CRHCorticoliberin. (196 aa)
LYNTyrosine-protein kinase. (512 aa)
GRIA3Glutamate receptor 3. (894 aa)
GNAI2Guanine nucleotide-binding protein G(I) subunit alpha-2. (355 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1230 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2584 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
PLA2G4APhospholipase A2. (733 aa)
GNA12Guanine nucleotide-binding protein subunit alpha-12. (305 aa)
PPP2R1ASerine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform isoform X1. (589 aa)
IGF1RTyrosine-protein kinase receptor. (1367 aa)
ARAFSerine/threonine-protein kinase A-Raf. (606 aa)
GRID2Glutamate receptor ionotropic, delta-2; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (632 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
ERASGTPase ERas. (233 aa)
LOC110570357Corticotropin-releasing factor receptor 1; Belongs to the G-protein coupled receptor 2 family. (421 aa)
GNA13Guanine nucleotide-binding protein subunit alpha-13 isoform X1. (377 aa)
LOC110569839Neuroendocrine secretory protein 55. (246 aa)
GNASGuanine nucleotide-binding protein G(S) subunit alpha isoforms XLas isoform X1. (1003 aa)
GNA11Guanine nucleotide-binding protein subunit alpha-11. (359 aa)
GNAO1Guanine nucleotide-binding protein G(O) subunit alpha. (354 aa)
CACNA1AVoltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents. (2504 aa)
MAP2K2Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa)
PPP2CASerine/threonine-protein phosphatase. (309 aa)
PRKG2cGMP-dependent protein kinase. (762 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
Your Current Organism:
Neomonachus schauinslandi
NCBI taxonomy Id: 29088
Other names: Hawaiian monk seal, Monachus schauinslandi, N. schauinslandi
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