STRINGSTRING
GRIA2 GRIA2 GNAS GNAS LOC110569839 LOC110569839 GNA13 GNA13 LOC110570357 LOC110570357 ERAS ERAS PRKCA PRKCA GRID2 GRID2 ARAF ARAF IGF1R IGF1R PPP2R1A PPP2R1A GNA12 GNA12 PLA2G4A PLA2G4A PRKCG PRKCG ITPR3 ITPR3 PLCB3 PLCB3 GNAI2 GNAI2 GRIA3 GRIA3 LYN LYN CRH CRH PRKCB PRKCB PLCB4 PLCB4 MAPK1 MAPK1 LOC110579802 LOC110579802 GNAI1 GNAI1 IGF1 IGF1 PPP1R17 PPP1R17 CSDE1 CSDE1 GNAZ GNAZ GNAI3 GNAI3 KRAS KRAS ITPR2 ITPR2 LOC110579709 LOC110579709 PLCB1 PLCB1 NRAS NRAS HRAS HRAS BRAF BRAF GRM1 GRM1 MAP2K1 MAP2K1 PPP2CB PPP2CB ITPR1 ITPR1 RAF1 RAF1 PLCB2 PLCB2 JMJD7 JMJD7 PLA2G4F PLA2G4F PLA2G4B PLA2G4B PLA2G4D PLA2G4D PPP2R1B PPP2R1B GUCY1A2 GUCY1A2 GRIA1 GRIA1 PLA2G4E PLA2G4E PRKG1 PRKG1 FBXO21 FBXO21 GUCY1A3 GUCY1A3 NOS1 NOS1 GUCY1B3 GUCY1B3 MAPK3 MAPK3 RYR1 RYR1 PRKG2 PRKG2 PPP2CA PPP2CA MAP2K2 MAP2K2 CACNA1A CACNA1A GNAO1 GNAO1 GNA11 GNA11
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GRIA2Glutamate receptor 2 isoform X1. (940 aa)
GNASGuanine nucleotide-binding protein G(S) subunit alpha isoforms XLas isoform X1. (1003 aa)
LOC110569839Neuroendocrine secretory protein 55. (246 aa)
GNA13Guanine nucleotide-binding protein subunit alpha-13 isoform X1. (377 aa)
LOC110570357Corticotropin-releasing factor receptor 1; Belongs to the G-protein coupled receptor 2 family. (421 aa)
ERASGTPase ERas. (233 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
GRID2Glutamate receptor ionotropic, delta-2; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (632 aa)
ARAFSerine/threonine-protein kinase A-Raf. (606 aa)
IGF1RTyrosine-protein kinase receptor. (1367 aa)
PPP2R1ASerine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform isoform X1. (589 aa)
GNA12Guanine nucleotide-binding protein subunit alpha-12. (305 aa)
PLA2G4APhospholipase A2. (733 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2584 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1230 aa)
GNAI2Guanine nucleotide-binding protein G(I) subunit alpha-2. (355 aa)
GRIA3Glutamate receptor 3. (894 aa)
LYNTyrosine-protein kinase. (512 aa)
CRHCorticoliberin. (196 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (634 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1194 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (361 aa)
LOC110579802LOW QUALITY PROTEIN: guanylate cyclase soluble subunit beta-2-like; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (646 aa)
GNAI1Guanine nucleotide-binding protein G(I) subunit alpha-1. (354 aa)
IGF1Insulin-like growth factor I isoform X1. (185 aa)
PPP1R17Protein phosphatase 1 regulatory subunit 17. (155 aa)
CSDE1Cold shock domain-containing protein E1 isoform X1. (798 aa)
GNAZGuanine nucleotide-binding protein G(Z) subunit alpha. (355 aa)
GNAI3Guanine nucleotide-binding protein G(K) subunit alpha. (354 aa)
KRASGTPase KRas. (188 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2701 aa)
LOC110579709Guanine nucleotide-binding protein G(Q) subunit alpha. (301 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
NRASGTPase NRas. (189 aa)
HRASGTPase HRas isoform X1. (189 aa)
BRAFSerine/threonine-protein kinase B-raf. (764 aa)
GRM1Metabotropic glutamate receptor 1 isoform X1. (1190 aa)
MAP2K1Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
PPP2CBSerine/threonine-protein phosphatase. (309 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1 isoform X1. (2709 aa)
RAF1RAF proto-oncogene serine/threonine-protein kinase. (648 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1186 aa)
JMJD7jmjC domain-containing protein 7. (316 aa)
PLA2G4FPhospholipase A2. (860 aa)
PLA2G4BPhospholipase A2. (782 aa)
PLA2G4DPhospholipase A2. (817 aa)
PPP2R1BSerine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform isoform X2. (693 aa)
GUCY1A2Guanylate cyclase soluble subunit alpha-2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (673 aa)
GRIA1Glutamate receptor 1 isoform X1. (906 aa)
PLA2G4EPhospholipase A2. (841 aa)
PRKG1cGMP-dependent protein kinase. (726 aa)
FBXO21F-box only protein 21 isoform X1. (627 aa)
GUCY1A3Guanylate cyclase soluble subunit alpha-3; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (690 aa)
NOS1Nitric oxide synthase, brain isoform X1. (1467 aa)
GUCY1B3Guanylate cyclase soluble subunit beta-1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (637 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
RYR1Ryanodine receptor 1. (4995 aa)
PRKG2cGMP-dependent protein kinase. (762 aa)
PPP2CASerine/threonine-protein phosphatase. (309 aa)
MAP2K2Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa)
CACNA1AVoltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents. (2504 aa)
GNAO1Guanine nucleotide-binding protein G(O) subunit alpha. (354 aa)
GNA11Guanine nucleotide-binding protein subunit alpha-11. (359 aa)
Your Current Organism:
Neomonachus schauinslandi
NCBI taxonomy Id: 29088
Other names: Hawaiian monk seal, Monachus schauinslandi, N. schauinslandi
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