STRINGSTRING
MAPK3 MAPK3 CDC23 CDC23 CDC25C CDC25C PIK3R1 PIK3R1 LOC110591391 LOC110591391 LOC110591392 LOC110591392 ADCY2 ADCY2 CNTD2 CNTD2 CCNB1 CCNB1 KIF22 KIF22 AKT2 AKT2 RRAD RRAD ADCY7 ADCY7 FZR1 FZR1 ADCY6 ADCY6 ADCY1 ADCY1 PRKACA PRKACA RPS6KA6 RPS6KA6 RPS6KA2 RPS6KA2 BRAF BRAF PRKACB PRKACB ADCY5 ADCY5 PIK3CA PIK3CA MAD2L1 MAD2L1 HSP90AB1 HSP90AB1 REM1 REM1 AP5S1 AP5S1 CDC26 CDC26 ANAPC2 ANAPC2 ADCY8 ADCY8 GEM GEM LOC110585707 LOC110585707 KRAS KRAS GNAI3 GNAI3 MAPK9 MAPK9 IGF1 IGF1 GNAI1 GNAI1 MAPK1 MAPK1 MAPK11 MAPK11 CDC25B CDC25B MOS MOS MAPK12 MAPK12 ANAPC11 ANAPC11 SPDYC SPDYC CDK2 CDK2 INS INS CDC25A CDC25A PLK1 PLK1 GNAI2 GNAI2 PIK3CD PIK3CD PIK3R3 PIK3R3 PDE3B PDE3B TMEM82 TMEM82 MAPK14 MAPK14 MAPK13 MAPK13 RPS6KA1 RPS6KA1 CPEB4 CPEB4 ADCY4 ADCY4 RAF1 RAF1 AURKB AURKB CCNB2 CCNB2 PGR PGR PIK3CB PIK3CB CPEB2 CPEB2 ANAPC10 ANAPC10 ANAPC13 ANAPC13 CDC27 CDC27 CCNA1 CCNA1 AURKA AURKA CPEB3 CPEB3 PTRHD1 PTRHD1 CDK1 CDK1 PKMYT1 PKMYT1 SPDYA SPDYA ANAPC1 ANAPC1 ANAPC7 ANAPC7 STK10 STK10 CDC16 CDC16 LOC110587496 LOC110587496 ADCY3 ADCY3 MAD2L2 MAD2L2 PIK3R2 PIK3R2 AKT3 AKT3 AURKC AURKC RPS6KA3 RPS6KA3 CCNA2 CCNA2 AKT1 AKT1 CDK3 CDK3 IGF1R IGF1R ANAPC4 ANAPC4 CPEB1 CPEB1 ARAF ARAF MAD1L1 MAD1L1 LOC110571866 LOC110571866 CCNB3 CCNB3 HSP90AA1 HSP90AA1 BUB1 BUB1 ADCY9 ADCY9 MAPK8 MAPK8 ANAPC5 ANAPC5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
CDC23Cell division cycle protein 23 homolog. (597 aa)
CDC25CM-phase inducer phosphatase 3. (529 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (725 aa)
LOC110591391Mitogen-activated protein kinase 10-like. (176 aa)
LOC110591392Mitogen-activated protein kinase. (300 aa)
ADCY2Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1091 aa)
CNTD2Cyclin N-terminal domain-containing protein 2; Belongs to the cyclin family. (329 aa)
CCNB1G2/mitotic-specific cyclin-B1; Belongs to the cyclin family. (427 aa)
KIF22Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (660 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
RRADGTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (308 aa)
ADCY7Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1075 aa)
FZR1Fizzy-related protein homolog isoform X1. (496 aa)
ADCY6Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1161 aa)
ADCY1Adenylate cyclase type 1. (921 aa)
PRKACAcAMP-dependent protein kinase catalytic subunit alpha; Belongs to the protein kinase superfamily. (351 aa)
RPS6KA6Ribosomal protein S6 kinase. (744 aa)
RPS6KA2Ribosomal protein S6 kinase. (727 aa)
BRAFSerine/threonine-protein kinase B-raf. (764 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta; Belongs to the protein kinase superfamily. (397 aa)
ADCY5Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1205 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
MAD2L1LOW QUALITY PROTEIN: mitotic spindle assembly checkpoint protein MAD2A. (111 aa)
HSP90AB1Heat shock protein HSP 90-beta. (724 aa)
REM1GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (298 aa)
AP5S1AP-5 complex subunit sigma-1. (200 aa)
CDC26Anaphase-promoting complex subunit CDC26. (85 aa)
ANAPC2Anaphase-promoting complex subunit 2 isoform X1; Belongs to the cullin family. (818 aa)
ADCY8Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1250 aa)
GEMGTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (295 aa)
LOC110585707LOW QUALITY PROTEIN: aurora kinase A-like. (266 aa)
KRASGTPase KRas. (188 aa)
GNAI3Guanine nucleotide-binding protein G(K) subunit alpha. (354 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
IGF1Insulin-like growth factor I isoform X1. (185 aa)
GNAI1Guanine nucleotide-binding protein G(I) subunit alpha-1. (354 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (361 aa)
MAPK11Mitogen-activated protein kinase. (364 aa)
CDC25BLOW QUALITY PROTEIN: M-phase inducer phosphatase 2. (574 aa)
MOSProto-oncogene serine/threonine-protein kinase mos; Belongs to the protein kinase superfamily. (348 aa)
MAPK12Mitogen-activated protein kinase. (367 aa)
ANAPC11Anaphase-promoting complex subunit 11. (84 aa)
SPDYCLOW QUALITY PROTEIN: speedy protein C. (280 aa)
CDK2Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily. (298 aa)
INSInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa)
CDC25AM-phase inducer phosphatase 1. (522 aa)
PLK1Serine/threonine-protein kinase PLK. (604 aa)
GNAI2Guanine nucleotide-binding protein G(I) subunit alpha-2. (355 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa)
PIK3R3Phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1. (507 aa)
PDE3BPhosphodiesterase. (1167 aa)
TMEM82Transmembrane protein 82. (344 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
MAPK13Mitogen-activated protein kinase. (365 aa)
RPS6KA1Ribosomal protein S6 kinase. (744 aa)
CPEB4Cytoplasmic polyadenylation element-binding protein 4. (668 aa)
ADCY4Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
RAF1RAF proto-oncogene serine/threonine-protein kinase. (648 aa)
AURKBAurora kinase B isoform X1; Belongs to the protein kinase superfamily. (344 aa)
CCNB2G2/mitotic-specific cyclin-B2; Belongs to the cyclin family. (397 aa)
PGRProgesterone receptor isoform X1. (930 aa)
PIK3CBLOW QUALITY PROTEIN: phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform; Belongs to the PI3/PI4-kinase family. (1070 aa)
CPEB2Cytoplasmic polyadenylation element-binding protein 2 isoform X1. (1044 aa)
ANAPC10Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. (185 aa)
ANAPC13Anaphase-promoting complex subunit 13. (74 aa)
CDC27Cell division cycle protein 27 homolog. (825 aa)
CCNA1cyclin-A1; Belongs to the cyclin family. (421 aa)
AURKAAurora kinase A; Belongs to the protein kinase superfamily. (405 aa)
CPEB3Cytoplasmic polyadenylation element-binding protein 3 isoform X1. (712 aa)
PTRHD1Putative peptidyl-tRNA hydrolase PTRHD1. (140 aa)
CDK1Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily. (297 aa)
PKMYT1Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase isoform X1; Belongs to the protein kinase superfamily. (494 aa)
SPDYASpeedy protein A isoform X1. (312 aa)
ANAPC1Anaphase-promoting complex subunit 1. (1944 aa)
ANAPC7Anaphase-promoting complex subunit 7. (601 aa)
STK10Serine/threonine-protein kinase 10. (967 aa)
CDC16Cell division cycle protein 16 homolog isoform X1. (620 aa)
LOC110587496Speedy protein E4-like. (214 aa)
ADCY3Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1145 aa)
MAD2L2Mitotic spindle assembly checkpoint protein MAD2B. (211 aa)
PIK3R2Phosphatidylinositol 3-kinase regulatory subunit beta isoform X1. (726 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
AURKCAurora kinase C; Belongs to the protein kinase superfamily. (333 aa)
RPS6KA3Ribosomal protein S6 kinase. (740 aa)
CCNA2cyclin-A2; Belongs to the cyclin family. (432 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
CDK3Cyclin-dependent kinase 3 isoform X1; Belongs to the protein kinase superfamily. (452 aa)
IGF1RTyrosine-protein kinase receptor. (1367 aa)
ANAPC4Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. (808 aa)
CPEB1Cytoplasmic polyadenylation element-binding protein 1 isoform X2. (491 aa)
ARAFSerine/threonine-protein kinase A-Raf. (606 aa)
MAD1L1Mitotic spindle assembly checkpoint protein MAD1 isoform X2. (717 aa)
LOC110571866Speedy protein E4-like. (240 aa)
CCNB3G2/mitotic-specific cyclin-B3; Belongs to the cyclin family. (1324 aa)
HSP90AA1Heat shock protein HSP 90-alpha. (733 aa)
BUB1Mitotic checkpoint serine/threonine-protein kinase BUB1. (1084 aa)
ADCY9Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1352 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
ANAPC5Anaphase-promoting complex subunit 5 isoform X1. (755 aa)
Your Current Organism:
Neomonachus schauinslandi
NCBI taxonomy Id: 29088
Other names: Hawaiian monk seal, Monachus schauinslandi, N. schauinslandi
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