STRINGSTRING
ADCY9 ADCY9 CAMK2G CAMK2G TCF7L2 TCF7L2 PTRHD1 PTRHD1 EDNRB EDNRB TCF7L1 TCF7L1 WNT16 WNT16 POMC POMC ARSI ARSI FZD3 FZD3 CREBBP CREBBP ADCY3 ADCY3 MITF MITF CAMK2A CAMK2A EDN1 EDN1 WNT9A WNT9A LOC110586587 LOC110586587 CALML5 CALML5 CALML4 CALML4 DCT DCT ADCY4 ADCY4 PLCB2 PLCB2 RAF1 RAF1 WNT7A WNT7A WNT5A WNT5A DVL2 DVL2 MAP2K1 MAP2K1 CREB3L2 CREB3L2 PRKACB PRKACB GSK3B GSK3B ADCY5 ADCY5 DVL3 DVL3 HRAS HRAS WNT2B WNT2B NRAS NRAS REM1 REM1 CREB3 CREB3 PLCB1 PLCB1 ADCY8 ADCY8 GEM GEM WNT5B WNT5B KRAS KRAS GNAI3 GNAI3 CSDE1 CSDE1 FZD6 FZD6 FZD1 FZD1 GNAI1 GNAI1 MAPK1 MAPK1 ASIP ASIP PLCB4 PLCB4 EP300 EP300 PRKCB PRKCB LOC110578691 LOC110578691 FZD8 FZD8 WNT7B WNT7B KITLG KITLG GNAI2 GNAI2 CAMK2D CAMK2D FZD4 FZD4 LEF1 LEF1 WNT4 WNT4 PLCB3 PLCB3 CREB3L1 CREB3L1 CALML6 CALML6 DVL1 DVL1 PRKCG PRKCG TYRP1 TYRP1 CREB3L4 CREB3L4 FZD2 FZD2 LOC110572425 LOC110572425 CALM1 CALM1 WNT3 WNT3 PRKCA PRKCA EFCAB13 EFCAB13 TYR TYR ERAS ERAS EFCAB3 EFCAB3 WNT9B WNT9B CTNNB1 CTNNB1 LOC110569839 LOC110569839 GNAS GNAS WNT1 WNT1 WNT11 WNT11 GNAO1 GNAO1 FZD5 FZD5 PRKACA PRKACA CREB3L3 CREB3L3 ADCY1 ADCY1 FZD7 FZD7 ADCY6 ADCY6 MAP2K2 MAP2K2 ADCY7 ADCY7 WNT10B WNT10B LOC110592076 LOC110592076 RRAD RRAD CAMK2B CAMK2B TCF7 TCF7 LOC110592210 LOC110592210 CREB1 CREB1 WNT6 WNT6 LOC110592156 LOC110592156 WNT10A WNT10A ADCY2 ADCY2 WNT8B WNT8B WNT8A WNT8A WNT2 WNT2 KIT KIT MAPK3 MAPK3 FZD10 FZD10 FZD9 FZD9
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ADCY9Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1352 aa)
CAMK2GCalcium/calmodulin-dependent protein kinase type II subunit gamma isoform X1. (606 aa)
TCF7L2Transcription factor 7-like 2. (446 aa)
PTRHD1Putative peptidyl-tRNA hydrolase PTRHD1. (140 aa)
EDNRBLOW QUALITY PROTEIN: endothelin B receptor; Belongs to the G-protein coupled receptor 1 family. (540 aa)
TCF7L1Transcription factor 7-like 1. (463 aa)
WNT16Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (361 aa)
POMCPro-opiomelanocortin. (265 aa)
ARSIArylsulfatase I. (575 aa)
FZD3Frizzled-3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
CREBBPCREB-binding protein isoform X3. (2433 aa)
ADCY3Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1145 aa)
MITFMicrophthalmia-associated transcription factor isoform X1. (504 aa)
CAMK2ACalcium/calmodulin-dependent protein kinase type II subunit alpha; Belongs to the protein kinase superfamily. (489 aa)
EDN1Endothelin-1. (202 aa)
WNT9AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (346 aa)
LOC110586587Calmodulin-like protein 3; Belongs to the calmodulin family. (149 aa)
CALML5Calmodulin-like protein 5. (149 aa)
CALML4LOW QUALITY PROTEIN: calmodulin-like protein 4. (197 aa)
DCTL-dopachrome tautomerase. (548 aa)
ADCY4Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1186 aa)
RAF1RAF proto-oncogene serine/threonine-protein kinase. (648 aa)
WNT7AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (349 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
DVL2Segment polarity protein dishevelled homolog DVL-2. (734 aa)
MAP2K1Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
CREB3L2Cyclic AMP-responsive element-binding protein 3-like protein 2. (520 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta; Belongs to the protein kinase superfamily. (397 aa)
GSK3BGlycogen synthase kinase-3 beta isoform X1; Belongs to the protein kinase superfamily. (433 aa)
ADCY5Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1205 aa)
DVL3Segment polarity protein dishevelled homolog DVL-3 isoform X1. (718 aa)
HRASGTPase HRas isoform X1. (189 aa)
WNT2BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (393 aa)
NRASGTPase NRas. (189 aa)
REM1GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (298 aa)
CREB3Cyclic AMP-responsive element-binding protein 3 isoform X2. (352 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
ADCY8Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1250 aa)
GEMGTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (295 aa)
WNT5BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (358 aa)
KRASGTPase KRas. (188 aa)
GNAI3Guanine nucleotide-binding protein G(K) subunit alpha. (354 aa)
CSDE1Cold shock domain-containing protein E1 isoform X1. (798 aa)
FZD6Frizzled-6 isoform X1; Belongs to the G-protein coupled receptor Fz/Smo family. (712 aa)
FZD1Frizzled-1; Belongs to the G-protein coupled receptor Fz/Smo family. (648 aa)
GNAI1Guanine nucleotide-binding protein G(I) subunit alpha-1. (354 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (361 aa)
ASIPAgouti-signaling protein. (134 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1194 aa)
EP300Histone acetyltransferase p300. (2420 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (634 aa)
LOC110578691Frizzled-8; Belongs to the G-protein coupled receptor Fz/Smo family. (338 aa)
FZD8Frizzled-8. (243 aa)
WNT7BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (349 aa)
KITLGKit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (274 aa)
GNAI2Guanine nucleotide-binding protein G(I) subunit alpha-2. (355 aa)
CAMK2DCalcium/calmodulin-dependent protein kinase type II subunit delta isoform X4. (525 aa)
FZD4Frizzled-4; Belongs to the G-protein coupled receptor Fz/Smo family. (537 aa)
LEF1Lymphoid enhancer-binding factor 1 isoform X1. (399 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (424 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1230 aa)
CREB3L1Cyclic AMP-responsive element-binding protein 3-like protein 1. (520 aa)
CALML6Calmodulin-like protein 6. (232 aa)
DVL1Segment polarity protein dishevelled homolog DVL-1 isoform X1. (693 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
TYRP15,6-dihydroxyindole-2-carboxylic acid oxidase. (536 aa)
CREB3L4Cyclic AMP-responsive element-binding protein 3-like protein 4 isoform X2. (394 aa)
FZD2Frizzled-2; Belongs to the G-protein coupled receptor Fz/Smo family. (565 aa)
LOC110572425Parvalbumin beta-like. (129 aa)
CALM1Calmodulin-1; Belongs to the calmodulin family. (149 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (400 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
EFCAB13LOW QUALITY PROTEIN: EF-hand calcium-binding domain-containing protein 13. (906 aa)
TYRTyrosinase. (531 aa)
ERASGTPase ERas. (233 aa)
EFCAB3EF-hand calcium-binding domain-containing protein 3 isoform X1. (646 aa)
WNT9BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (477 aa)
CTNNB1Catenin beta-1. (781 aa)
LOC110569839Neuroendocrine secretory protein 55. (246 aa)
GNASGuanine nucleotide-binding protein G(S) subunit alpha isoforms XLas isoform X1. (1003 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
GNAO1Guanine nucleotide-binding protein G(O) subunit alpha. (354 aa)
FZD5Frizzled-5; Belongs to the G-protein coupled receptor Fz/Smo family. (590 aa)
PRKACAcAMP-dependent protein kinase catalytic subunit alpha; Belongs to the protein kinase superfamily. (351 aa)
CREB3L3Cyclic AMP-responsive element-binding protein 3-like protein 3. (302 aa)
ADCY1Adenylate cyclase type 1. (921 aa)
FZD7Frizzled-7; Belongs to the G-protein coupled receptor Fz/Smo family. (574 aa)
ADCY6Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1161 aa)
MAP2K2Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa)
ADCY7Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1075 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
LOC110592076Calmodulin-like; Belongs to the calmodulin family. (210 aa)
RRADGTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (308 aa)
CAMK2BCalcium/calmodulin-dependent protein kinase type II subunit beta. (651 aa)
TCF7Transcription factor 7. (419 aa)
LOC110592210Calmodulin-like; Belongs to the calmodulin family. (149 aa)
CREB1Cyclic AMP-responsive element-binding protein 1. (327 aa)
WNT6Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (362 aa)
LOC110592156Calmodulin-like; Belongs to the calmodulin family. (98 aa)
WNT10AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (452 aa)
ADCY2Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1091 aa)
WNT8BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (329 aa)
WNT8AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
KITMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (977 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
FZD10Frizzled-10; Belongs to the G-protein coupled receptor Fz/Smo family. (581 aa)
FZD9Frizzled-9; Belongs to the G-protein coupled receptor Fz/Smo family. (586 aa)
Your Current Organism:
Neomonachus schauinslandi
NCBI taxonomy Id: 29088
Other names: Hawaiian monk seal, Monachus schauinslandi, N. schauinslandi
Server load: low (14%) [HD]