STRINGSTRING
GNAS GNAS LOC110569839 LOC110569839 SERPINA7 SERPINA7 PRKCA PRKCA ATP1B3 ATP1B3 TSHR TSHR SERPINA9 SERPINA9 LOC110573336 LOC110573336 ATP1A4 ATP1A4 CREB3L4 CREB3L4 ATP1B1 ATP1B1 SLC5A5 SLC5A5 PRKCG PRKCG SLC26A4 SLC26A4 GPX7 GPX7 ITPR3 ITPR3 CREB3L1 CREB3L1 PLCB3 PLCB3 GPX1 GPX1 HSP90B1 HSP90B1 ATP1B4 ATP1B4 TTR TTR TG TG PRKCB PRKCB PLCB4 PLCB4 ATF2 ATF2 CREB5 CREB5 CANX CANX TTF2 TTF2 SYCP1 SYCP1 ATP1A1 ATP1A1 ITPR2 ITPR2 ADCY8 ADCY8 PLCB1 PLCB1 CREB3 CREB3 ATP1A3 ATP1A3 ADCY5 ADCY5 TSHB TSHB PRKACB PRKACB PDIA4 PDIA4 CREB3L2 CREB3L2 TTF1 TTF1 CGA CGA GSR GSR HSPA5 HSPA5 LOC110584598 LOC110584598 LOC110584610 LOC110584610 ITPR1 ITPR1 PLCB2 PLCB2 DUOXA2 DUOXA2 IYD IYD ADCY4 ADCY4 DUOX1 DUOX1 FXYD2 FXYD2 ASGR1 ASGR1 ATP1B2 ATP1B2 GPX6 GPX6 ADCY3 ADCY3 LOC110585337 LOC110585337 TPO TPO PAX8 PAX8 DUOX2 DUOX2 GPX5 GPX5 ATF6B ATF6B PTRHD1 PTRHD1 ADCY9 ADCY9 GPX3 GPX3 ALB ALB ADCY2 ADCY2 GPX2 GPX2 CREB1 CREB1 GPX8 GPX8 ADCY7 ADCY7 ADCY6 ADCY6 LRP2 LRP2 ADCY1 ADCY1 CREB3L3 CREB3L3 PRKACA PRKACA ATF4 ATF4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GNASGuanine nucleotide-binding protein G(S) subunit alpha isoforms XLas isoform X1. (1003 aa)
LOC110569839Neuroendocrine secretory protein 55. (246 aa)
SERPINA7Thyroxine-binding globulin; Belongs to the serpin family. (414 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
ATP1B3Sodium/potassium-transporting ATPase subunit beta-3. (350 aa)
TSHRThyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (764 aa)
SERPINA9Serpin A9 isoform X1; Belongs to the serpin family. (431 aa)
LOC110573336Sodium/potassium-transporting ATPase subunit alpha. (1073 aa)
ATP1A4Sodium/potassium-transporting ATPase subunit alpha. (1030 aa)
CREB3L4Cyclic AMP-responsive element-binding protein 3-like protein 4 isoform X2. (394 aa)
ATP1B1Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (303 aa)
SLC5A5Sodium/iodide cotransporter; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (642 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
SLC26A4Pendrin; Sodium-independent transporter of chloride and iodide. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (780 aa)
GPX7Glutathione peroxidase; Belongs to the glutathione peroxidase family. (186 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2584 aa)
CREB3L1Cyclic AMP-responsive element-binding protein 3-like protein 1. (520 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1230 aa)
GPX1Glutathione peroxidase; Belongs to the glutathione peroxidase family. (209 aa)
HSP90B1LOW QUALITY PROTEIN: endoplasmin. (804 aa)
ATP1B4Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (360 aa)
TTRTransthyretin; Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain. (147 aa)
TGThyroglobulin. (2762 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (634 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1194 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2 isoform X1. (505 aa)
CREB5Cyclic AMP-responsive element-binding protein 5. (501 aa)
CANXCalnexin. (594 aa)
TTF2Transcription termination factor 2. (1143 aa)
SYCP1Synaptonemal complex protein 1 isoform X1. (977 aa)
ATP1A1Sodium/potassium-transporting ATPase subunit alpha. (1021 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2701 aa)
ADCY8Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1250 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
CREB3Cyclic AMP-responsive element-binding protein 3 isoform X2. (352 aa)
ATP1A3Sodium/potassium-transporting ATPase subunit alpha-3; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (1121 aa)
ADCY5Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1205 aa)
TSHBThyrotropin subunit beta. (158 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta; Belongs to the protein kinase superfamily. (397 aa)
PDIA4Protein disulfide-isomerase A4. (644 aa)
CREB3L2Cyclic AMP-responsive element-binding protein 3-like protein 2. (520 aa)
TTF1Transcription termination factor 1 isoform X1. (763 aa)
CGAGlycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. (120 aa)
GSRGlutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (519 aa)
HSPA578 kDa glucose-regulated protein; Belongs to the heat shock protein 70 family. (654 aa)
LOC110584598C-type lectin domain family 10 member A-like. (307 aa)
LOC110584610Asialoglycoprotein receptor 2-like isoform X1. (307 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1 isoform X1. (2709 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1186 aa)
DUOXA2Dual oxidase maturation factor 2. (320 aa)
IYDIodotyrosine deiodinase 1 isoform X1. (291 aa)
ADCY4Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
DUOX1Dual oxidase 1. (1428 aa)
FXYD2FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (64 aa)
ASGR1Asialoglycoprotein receptor 1. (284 aa)
ATP1B2Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (290 aa)
GPX6Glutathione peroxidase; Belongs to the glutathione peroxidase family. (218 aa)
ADCY3Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1145 aa)
LOC110585337Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (280 aa)
TPOLOW QUALITY PROTEIN: thyroid peroxidase. (940 aa)
PAX8Paired box protein Pax-8. (490 aa)
DUOX2Dual oxidase 2. (1543 aa)
GPX5Glutathione peroxidase; Belongs to the glutathione peroxidase family. (221 aa)
ATF6BCyclic AMP-dependent transcription factor ATF-6 beta isoform X1. (711 aa)
PTRHD1Putative peptidyl-tRNA hydrolase PTRHD1. (140 aa)
ADCY9Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1352 aa)
GPX3Glutathione peroxidase; Belongs to the glutathione peroxidase family. (226 aa)
ALBSerum albumin. (608 aa)
ADCY2Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1091 aa)
GPX2Glutathione peroxidase; Belongs to the glutathione peroxidase family. (190 aa)
CREB1Cyclic AMP-responsive element-binding protein 1. (327 aa)
GPX8Glutathione peroxidase; Belongs to the glutathione peroxidase family. (209 aa)
ADCY7Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1075 aa)
ADCY6Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1161 aa)
LRP2LOW QUALITY PROTEIN: low-density lipoprotein receptor-related protein 2. (4645 aa)
ADCY1Adenylate cyclase type 1. (921 aa)
CREB3L3Cyclic AMP-responsive element-binding protein 3-like protein 3. (302 aa)
PRKACAcAMP-dependent protein kinase catalytic subunit alpha; Belongs to the protein kinase superfamily. (351 aa)
ATF4Cyclic AMP-dependent transcription factor ATF-4. (351 aa)
Your Current Organism:
Neomonachus schauinslandi
NCBI taxonomy Id: 29088
Other names: Hawaiian monk seal, Monachus schauinslandi, N. schauinslandi
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