STRINGSTRING
GNAS GNAS LOC110569839 LOC110569839 PTGER3 PTGER3 ABHD5 ABHD5 IRS4 IRS4 TSHR TSHR PIK3CB PIK3CB LOC110571849 LOC110571849 PLIN1 PLIN1 AKT1 AKT1 ADRB3 ADRB3 AKT3 AKT3 IRS1 IRS1 PIK3R2 PIK3R2 PTGS2 PTGS2 NPPA NPPA PDE3B PDE3B PIK3R3 PIK3R3 PIK3CD PIK3CD LOC110575926 LOC110575926 ADORA1 ADORA1 GNAI2 GNAI2 INS INS FABP12 FABP12 LOC110579116 LOC110579116 GNAI1 GNAI1 SYCP1 SYCP1 GNAI3 GNAI3 LOC110579111 LOC110579111 PNPLA2 PNPLA2 ADCY8 ADCY8 FABP4 FABP4 PTGS1 PTGS1 NPY NPY PIK3CA PIK3CA ADCY5 ADCY5 TSHB TSHB PRKACB PRKACB CGA CGA AQP7 AQP7 MGLL MGLL ADCY4 ADCY4 IRS2 IRS2 ADRB2 ADRB2 ADCY3 ADCY3 PRKG1 PRKG1 LIPE LIPE PTRHD1 PTRHD1 ADRB1 ADRB1 ADCY9 ADCY9 NPY1R NPY1R PIK3R1 PIK3R1 PRKG2 PRKG2 ADCY2 ADCY2 AKT2 AKT2 ADCY7 ADCY7 ADCY6 ADCY6 PRKACA PRKACA INSR INSR ADCY1 ADCY1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GNASGuanine nucleotide-binding protein G(S) subunit alpha isoforms XLas isoform X1. (1003 aa)
LOC110569839Neuroendocrine secretory protein 55. (246 aa)
PTGER3Prostaglandin E2 receptor EP3 subtype. (387 aa)
ABHD51-acylglycerol-3-phosphate O-acyltransferase ABHD5. (350 aa)
IRS4Insulin receptor substrate 4. (1244 aa)
TSHRThyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (764 aa)
PIK3CBLOW QUALITY PROTEIN: phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform; Belongs to the PI3/PI4-kinase family. (1070 aa)
LOC110571849Insulin receptor substrate 1-like. (404 aa)
PLIN1Perilipin; Belongs to the perilipin family. (477 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
ADRB3Beta-3 adrenergic receptor isoform X1. (399 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
IRS1Insulin receptor substrate 1. (1236 aa)
PIK3R2Phosphatidylinositol 3-kinase regulatory subunit beta isoform X1. (726 aa)
PTGS2Prostaglandin G/H synthase 2. (604 aa)
NPPANatriuretic peptides A. (152 aa)
PDE3BPhosphodiesterase. (1167 aa)
PIK3R3Phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1. (507 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa)
LOC110575926HRAS-like suppressor 3. (162 aa)
ADORA1Adenosine receptor A1; Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (326 aa)
GNAI2Guanine nucleotide-binding protein G(I) subunit alpha-2. (355 aa)
INSInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa)
FABP12Fatty acid-binding protein 12; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (137 aa)
LOC110579116Myelin P2 protein; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (132 aa)
GNAI1Guanine nucleotide-binding protein G(I) subunit alpha-1. (354 aa)
SYCP1Synaptonemal complex protein 1 isoform X1. (977 aa)
GNAI3Guanine nucleotide-binding protein G(K) subunit alpha. (354 aa)
LOC110579111Fatty acid-binding protein 9-like; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (132 aa)
PNPLA2Patatin-like phospholipase domain-containing protein 2. (486 aa)
ADCY8Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1250 aa)
FABP4Fatty acid-binding protein, adipocyte; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (131 aa)
PTGS1Prostaglandin G/H synthase 1 isoform X1. (600 aa)
NPYPro-neuropeptide Y. (97 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
ADCY5Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1205 aa)
TSHBThyrotropin subunit beta. (158 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta; Belongs to the protein kinase superfamily. (397 aa)
CGAGlycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. (120 aa)
AQP7Aquaporin-7; Belongs to the MIP/aquaporin (TC 1.A.8) family. (342 aa)
MGLLMonoglyceride lipase isoform X1. (303 aa)
ADCY4Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
IRS2Insulin receptor substrate 2. (1330 aa)
ADRB2Beta-2 adrenergic receptor. (418 aa)
ADCY3Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1145 aa)
PRKG1cGMP-dependent protein kinase. (726 aa)
LIPEHormone-sensitive lipase isoform X1. (806 aa)
PTRHD1Putative peptidyl-tRNA hydrolase PTRHD1. (140 aa)
ADRB1Beta-1 adrenergic receptor; Belongs to the G-protein coupled receptor 1 family. (273 aa)
ADCY9Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1352 aa)
NPY1RNeuropeptide Y receptor type 1; Belongs to the G-protein coupled receptor 1 family. (382 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (725 aa)
PRKG2cGMP-dependent protein kinase. (762 aa)
ADCY2Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1091 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
ADCY7Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1075 aa)
ADCY6Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1161 aa)
PRKACAcAMP-dependent protein kinase catalytic subunit alpha; Belongs to the protein kinase superfamily. (351 aa)
INSRTyrosine-protein kinase receptor. (1368 aa)
ADCY1Adenylate cyclase type 1. (921 aa)
Your Current Organism:
Neomonachus schauinslandi
NCBI taxonomy Id: 29088
Other names: Hawaiian monk seal, Monachus schauinslandi, N. schauinslandi
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