STRINGSTRING
SCTR SCTR GNAS GNAS LOC110569839 LOC110569839 LOC110570878 LOC110570878 EPHX1 EPHX1 ATP1B3 ATP1B3 SLC10A1 SLC10A1 LOC110573336 LOC110573336 ATP1A4 ATP1A4 SLC25A39 SLC25A39 ATP1B1 ATP1B1 NR0B2 NR0B2 SLC9A1 SLC9A1 SLC2A1 SLC2A1 SLC22A20 SLC22A20 AQP4 AQP4 LOC110575919 LOC110575919 SLC22A8 SLC22A8 SLC9A3 SLC9A3 ATP1B4 ATP1B4 NR1H4 NR1H4 LOC110578952 LOC110578952 MINDY4 MINDY4 ABCB1 ABCB1 SLC25A40 SLC25A40 ABCB4 ABCB4 LOC110578364 LOC110578364 ATP1A1 ATP1A1 LOC110580871 LOC110580871 SLCO1A2 SLCO1A2 ADCY8 ADCY8 CA2 CA2 RXRA RXRA LOC110581717 LOC110581717 LOC110581808 LOC110581808 AQP1 AQP1 SLC22A7 SLC22A7 ATP1A3 ATP1A3 SLC51A SLC51A ADCY5 ADCY5 PRKACB PRKACB AQP9 AQP9 SLC27A5 SLC27A5 SLC51B SLC51B SLC4A2 SLC4A2 ADCY4 ADCY4 ABCC4 ABCC4 SLC10A2 SLC10A2 FXYD2 FXYD2 ATP1B2 ATP1B2 ADCY3 ADCY3 LOC110585337 LOC110585337 SLC4A5 SLC4A5 CFTR CFTR PTRHD1 PTRHD1 ADCY9 ADCY9 SCARB1 SCARB1 ABCG8 ABCG8 ABCG5 ABCG5 ABCC2 ABCC2 HMGCR HMGCR ABCG2 ABCG2 LOC110591405 LOC110591405 LOC110591531 LOC110591531 SLC4A4 SLC4A4 ADCY2 ADCY2 NCEH1 NCEH1 ABCB11 ABCB11 AQP8 AQP8 LOC110592481 LOC110592481 SLC5A1 SLC5A1 SLC9A5 SLC9A5 LOC110591360 LOC110591360 ADCY7 ADCY7 ADCY6 ADCY6 LDLR LDLR ADCY1 ADCY1 PRKACA PRKACA ABCC3 ABCC3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SCTRSecretin receptor; Belongs to the G-protein coupled receptor 2 family. (506 aa)
GNASGuanine nucleotide-binding protein G(S) subunit alpha isoforms XLas isoform X1. (1003 aa)
LOC110569839Neuroendocrine secretory protein 55. (246 aa)
LOC110570878UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (528 aa)
EPHX1Epoxide hydrolase; Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water. Belongs to the peptidase S33 family. (454 aa)
ATP1B3Sodium/potassium-transporting ATPase subunit beta-3. (350 aa)
SLC10A1Sodium/bile acid cotransporter. (385 aa)
LOC110573336Sodium/potassium-transporting ATPase subunit alpha. (1073 aa)
ATP1A4Sodium/potassium-transporting ATPase subunit alpha. (1030 aa)
SLC25A39Solute carrier family 25 member 39 isoform X1; Belongs to the mitochondrial carrier (TC 2.A.29) family. (366 aa)
ATP1B1Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (303 aa)
NR0B2Nuclear receptor subfamily 0 group B member 2. (279 aa)
SLC9A1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (816 aa)
SLC2A1Solute carrier family 2, facilitated glucose transporter member 1 isoform X1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (501 aa)
SLC22A20LOW QUALITY PROTEIN: solute carrier family 22 member 20. (556 aa)
AQP4Aquaporin-4 isoform X2; Belongs to the MIP/aquaporin (TC 1.A.8) family. (323 aa)
LOC110575919Solute carrier family 22 member 6 isoform X1. (547 aa)
SLC22A8Solute carrier family 22 member 8. (543 aa)
SLC9A3Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (841 aa)
ATP1B4Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (360 aa)
NR1H4Bile acid receptor isoform X1. (486 aa)
LOC110578952Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. (501 aa)
MINDY4Probable ubiquitin carboxyl-terminal hydrolase MINDY-4. (730 aa)
ABCB1Multidrug resistance protein 1. (1279 aa)
SLC25A40Solute carrier family 25 member 40; Belongs to the mitochondrial carrier (TC 2.A.29) family. (338 aa)
ABCB4Phosphatidylcholine translocator ABCB4 isoform X1. (1287 aa)
LOC110578364LOW QUALITY PROTEIN: sodium/glucose cotransporter 1-like; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (438 aa)
ATP1A1Sodium/potassium-transporting ATPase subunit alpha. (1021 aa)
LOC110580871Solute carrier organic anion transporter family member. (689 aa)
SLCO1A2Solute carrier organic anion transporter family member. (670 aa)
ADCY8Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1250 aa)
CA2Carbonic anhydrase 2; Belongs to the alpha-carbonic anhydrase family. (260 aa)
RXRARetinoic acid receptor RXR-alpha. (413 aa)
LOC110581717Acyl-coenzyme A amino acid N-acyltransferase 2-like. (487 aa)
LOC110581808LOW QUALITY PROTEIN: bile acid-CoA:amino acid N-acyltransferase-like. (421 aa)
AQP1Aquaporin-1; Belongs to the MIP/aquaporin (TC 1.A.8) family. (271 aa)
SLC22A7Solute carrier family 22 member 7 isoform X1. (553 aa)
ATP1A3Sodium/potassium-transporting ATPase subunit alpha-3; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (1121 aa)
SLC51AOrganic solute transporter subunit alpha. (363 aa)
ADCY5Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1205 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta; Belongs to the protein kinase superfamily. (397 aa)
AQP9Aquaporin-9; Belongs to the MIP/aquaporin (TC 1.A.8) family. (295 aa)
SLC27A5Bile acyl-CoA synthetase. (687 aa)
SLC51BOrganic solute transporter subunit beta. (128 aa)
SLC4A2Anion exchange protein. (1237 aa)
ADCY4Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
ABCC4Multidrug resistance-associated protein 4 isoform X2. (1325 aa)
SLC10A2Ileal sodium/bile acid cotransporter. (348 aa)
FXYD2FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (64 aa)
ATP1B2Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (290 aa)
ADCY3Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1145 aa)
LOC110585337Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (280 aa)
SLC4A5Anion exchange protein. (1115 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1573 aa)
PTRHD1Putative peptidyl-tRNA hydrolase PTRHD1. (140 aa)
ADCY9Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1352 aa)
SCARB1Scavenger receptor class B member 1; Belongs to the CD36 family. (509 aa)
ABCG8LOW QUALITY PROTEIN: ATP-binding cassette sub-family G member 8. (604 aa)
ABCG5LOW QUALITY PROTEIN: ATP-binding cassette sub-family G member 5. (622 aa)
ABCC2Canalicular multispecific organic anion transporter 1. (1545 aa)
HMGCR3-hydroxy-3-methylglutaryl coenzyme A reductase. (887 aa)
ABCG2ATP-binding cassette sub-family G member 2. (676 aa)
LOC110591405UDP-glucuronosyltransferase 2A2 isoform X1; Belongs to the UDP-glycosyltransferase family. (694 aa)
LOC110591531UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (530 aa)
SLC4A4Anion exchange protein. (1096 aa)
ADCY2Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1091 aa)
NCEH1Neutral cholesterol ester hydrolase 1. (408 aa)
ABCB11Bile salt export pump isoform X1. (1325 aa)
AQP8Aquaporin-8; Belongs to the MIP/aquaporin (TC 1.A.8) family. (263 aa)
LOC110592481Low affinity sodium-glucose cotransporter-like; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (338 aa)
SLC5A1Sodium/glucose cotransporter 1; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (662 aa)
SLC9A5Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (897 aa)
LOC110591360UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (247 aa)
ADCY7Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1075 aa)
ADCY6Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1161 aa)
LDLRLow-density lipoprotein receptor. (861 aa)
ADCY1Adenylate cyclase type 1. (921 aa)
PRKACAcAMP-dependent protein kinase catalytic subunit alpha; Belongs to the protein kinase superfamily. (351 aa)
ABCC3Canalicular multispecific organic anion transporter 2. (1523 aa)
Your Current Organism:
Neomonachus schauinslandi
NCBI taxonomy Id: 29088
Other names: Hawaiian monk seal, Monachus schauinslandi, N. schauinslandi
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