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| | MYD88 | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (321 aa) |
| | TNFRSF1A | Tumor necrosis factor receptor superfamily member 1A. (451 aa) |
| | ITGAX | Integrin alpha-X isoform X3; Belongs to the integrin alpha chain family. (1165 aa) |
| | CEBPG | CCAAT/enhancer-binding protein gamma. (145 aa) |
| | ITGAM | LOW QUALITY PROTEIN: integrin alpha-M; Belongs to the integrin alpha chain family. (1154 aa) |
| | LOC110591392 | Mitogen-activated protein kinase. (300 aa) |
| | LOC110591391 | Mitogen-activated protein kinase 10-like. (176 aa) |
| | PPP3CB | Serine/threonine-protein phosphatase. (527 aa) |
| | CD14 | Monocyte differentiation antigen CD14; Coreceptor for bacterial lipopolysaccharide. In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell su [...] (371 aa) |
| | TLR1 | LOW QUALITY PROTEIN: toll-like receptor 1; Belongs to the Toll-like receptor family. (788 aa) |
| | PPP3R1 | Calcineurin subunit B type 1. (170 aa) |
| | LOC110588386 | LOW QUALITY PROTEIN: toll-like receptor 2. (348 aa) |
| | TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa) |
| | ATP6V0A2 | V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (854 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa) |
| | MAPK8 | Mitogen-activated protein kinase. (427 aa) |
| | LOC110593796 | CD209 antigen-like protein E isoform X1. (252 aa) |
| | VDR | Vitamin D3 receptor. (427 aa) |
| | PLA2R1 | Secretory phospholipase A2 receptor. (1382 aa) |
| | KSR1 | Kinase suppressor of Ras 1. (739 aa) |
| | ATP6V0D1 | V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family. (351 aa) |
| | C3 | Complement C3. (1661 aa) |
| | CLEC4G | C-type lectin domain family 4 member G. (293 aa) |
| | NOS2 | Nitric oxide synthase; Produces nitric oxide (NO). (1157 aa) |
| | IRAK4 | Interleukin-1 receptor-associated kinase 4. (460 aa) |
| | CASP8 | LOW QUALITY PROTEIN: caspase-8; Belongs to the peptidase C14A family. (486 aa) |
| | NOD2 | Nucleotide-binding oligomerization domain-containing protein 2. (1013 aa) |
| | LOC110592076 | Calmodulin-like; Belongs to the calmodulin family. (210 aa) |
| | IL12A | Interleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (222 aa) |
| | TRADD | Tumor necrosis factor receptor type 1-associated DEATH domain protein isoform X1. (312 aa) |
| | HSPA9 | Stress-70 protein, mitochondrial; Belongs to the heat shock protein 70 family. (679 aa) |
| | CORO6 | Coronin; Belongs to the WD repeat coronin family. (472 aa) |
| | TLR10 | Toll-like receptor 10; Belongs to the Toll-like receptor family. (809 aa) |
| | TLR6 | Toll-like receptor 6; Belongs to the Toll-like receptor family. (794 aa) |
| | CAMK2B | Calcium/calmodulin-dependent protein kinase type II subunit beta. (651 aa) |
| | CORO1C | Coronin; Belongs to the WD repeat coronin family. (474 aa) |
| | LOC110592210 | Calmodulin-like; Belongs to the calmodulin family. (149 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) |
| | CASP10 | Caspase-10; Belongs to the peptidase C14A family. (481 aa) |
| | CREB1 | Cyclic AMP-responsive element-binding protein 1. (327 aa) |
| | CD74 | HLA class II histocompatibility antigen gamma chain isoform X1. (279 aa) |
| | STAT1 | Signal transducer and activator of transcription. (750 aa) |
| | LOC110592156 | Calmodulin-like; Belongs to the calmodulin family. (98 aa) |
| | LOC110592054 | Cytochrome c, testis-specific; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | HSPD1 | 60 kDa heat shock protein, mitochondrial; Belongs to the chaperonin (HSP60) family. (573 aa) |
| | CORO1A | Coronin; Belongs to the WD repeat coronin family. (461 aa) |
| | PPP1R14B | LOW QUALITY PROTEIN: protein phosphatase 1 regulatory subunit 14B-like. (203 aa) |
| | CAMK2D | Calcium/calmodulin-dependent protein kinase type II subunit delta isoform X4. (525 aa) |
| | LOC110575567 | HLA class II histocompatibility antigen, DM beta chain. (263 aa) |
| | LAMP2 | Lysosome-associated membrane glycoprotein 2 isoform X1. (411 aa) |
| | LOC110575636 | HLA class II histocompatibility antigen, DP alpha 1 chain; Belongs to the MHC class II family. (269 aa) |
| | BAD | Bcl2-associated agonist of cell death isoform X1. (205 aa) |
| | CAMP | Cathelicidin antimicrobial peptide. (171 aa) |
| | RAB5B | Ras-related protein Rab-5B isoform X1. (215 aa) |
| | IL23A | Interleukin-23 subunit alpha. (210 aa) |
| | LOC110577862 | 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial; Belongs to the cytochrome P450 family. (508 aa) |
| | EEA1 | Early endosome antigen 1. (1410 aa) |
| | ANKRA2 | Ankyrin repeat family A protein 2. (313 aa) |
| | TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (541 aa) |
| | APAF1 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1250 aa) |
| | NFYB | Nuclear transcription factor Y subunit beta. (207 aa) |
| | LSP1 | Lymphocyte-specific protein 1. (355 aa) |
| | MAPK12 | Mitogen-activated protein kinase. (367 aa) |
| | CTSS | Cathepsin S; Belongs to the peptidase C1 family. (340 aa) |
| | LOC110578553 | High affinity immunoglobulin gamma Fc receptor I-like. (350 aa) |
| | LOC110578430 | Integrin beta. (250 aa) |
| | ATP6V1H | V-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. (483 aa) |
| | RIPK2 | Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (538 aa) |
| | EP300 | Histone acetyltransferase p300. (2420 aa) |
| | SRC | Tyrosine-protein kinase. (536 aa) |
| | LBP | Lipopolysaccharide-binding protein. (481 aa) |
| | MAPK11 | Mitogen-activated protein kinase. (364 aa) |
| | MAPK1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (361 aa) |
| | IL6 | Interleukin-6 isoform X1. (212 aa) |
| | CUNH7orf31 | Uncharacterized protein C7orf31 homolog. (590 aa) |
| | MAPK9 | Mitogen-activated protein kinase. (424 aa) |
| | RFX5 | DNA-binding protein RFX5. (615 aa) |
| | BID | BH3-interacting domain death agonist; Counters the protective effect of Bcl-2. (240 aa) |
| | LOC110580835 | C-type lectin domain family 4 member A-like. (204 aa) |
| | ATP6V0B | V-type proton ATPase 21 kDa proteolipid subunit; Belongs to the V-ATPase proteolipid subunit family. (205 aa) |
| | CEBPB | CCAAT/enhancer-binding protein. (346 aa) |
| | LOC110575569 | HLA class II histocompatibility antigen, DM alpha chain; Belongs to the MHC class II family. (261 aa) |
| | LOC110575638 | LOW QUALITY PROTEIN: HLA class II histocompatibility antigen, DP beta 1 chain-like. (245 aa) |
| | NFYC | Nuclear transcription factor Y subunit gamma isoform X1. (439 aa) |
| | MALT1 | Mucosa-associated lymphoid tissue lymphoma translocation protein 1. (839 aa) |
| | PIK3C3 | Phosphatidylinositol 3-kinase catalytic subunit type 3. (887 aa) |
| | BCL2 | Apoptosis regulator Bcl-2 isoform X1. (234 aa) |
| | IL12B | Interleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (329 aa) |
| | TGFB2 | Transforming growth factor beta; Belongs to the TGF-beta family. (414 aa) |
| | CAMK2G | Calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X1. (606 aa) |
| | LOC110587828 | MHC class II transactivator-like. (103 aa) |
| | IFNA5 | LOW QUALITY PROTEIN: interferon alpha-5. (187 aa) |
| | LOC110586823 | CCAAT/enhancer-binding protein gamma-like. (138 aa) |
| | ARSI | Arylsulfatase I. (575 aa) |
| | IL1A | Interleukin-1; Belongs to the IL-1 family. (265 aa) |
| | LOC110587131 | Interferon alpha-16-like. (182 aa) |
| | PPP3CC | Serine/threonine-protein phosphatase. (525 aa) |
| | TLR2 | Toll-like receptor 2; Belongs to the Toll-like receptor family. (785 aa) |
| | TIRAP | Toll/interleukin-1 receptor domain-containing adapter protein. (223 aa) |
| | MRC1 | Macrophage mannose receptor 1. (1436 aa) |
| | FCGR3A | Low affinity immunoglobulin gamma Fc region receptor III-A. (248 aa) |
| | ARHGEF12 | Rho guanine nucleotide exchange factor 12 isoform X1. (1543 aa) |
| | FCGR2B | Low affinity immunoglobulin gamma Fc region receptor II-b. (295 aa) |
| | CREBBP | CREB-binding protein isoform X3. (2433 aa) |
| | ATP6V0C | V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (155 aa) |
| | LAMP1 | Lysosome-associated membrane glycoprotein 1 isoform X1. (413 aa) |
| | LOC110587829 | MHC class II transactivator-like. (1121 aa) |
| | RAB7A | Ras-related protein Rab-7a. (207 aa) |
| | IL1B | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (270 aa) |
| | IFNB1 | Interferon beta. (182 aa) |
| | IRAK2 | Interleukin-1 receptor-associated kinase-like 2. (624 aa) |
| | LOC110586769 | LOW QUALITY PROTEIN: HLA class II histocompatibility antigen, DR alpha chain; Belongs to the MHC class II family. (254 aa) |
| | LOC110584772 | Toll-like receptor 9 isoform X1. (1328 aa) |
| | CAMK2A | Calcium/calmodulin-dependent protein kinase type II subunit alpha; Belongs to the protein kinase superfamily. (489 aa) |
| | TNF | Tumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa) |
| | LOC110586587 | Calmodulin-like protein 3; Belongs to the calmodulin family. (149 aa) |
| | CALML5 | Calmodulin-like protein 5. (149 aa) |
| | IL18 | Interleukin-18 isoform X1. (344 aa) |
| | IL10RA | Interleukin-10 receptor subunit alpha. (575 aa) |
| | SYK | Tyrosine-protein kinase. (635 aa) |
| | CALML4 | LOW QUALITY PROTEIN: calmodulin-like protein 4. (197 aa) |
| | IFNGR1 | LOW QUALITY PROTEIN: interferon gamma receptor 1. (474 aa) |
| | LOC110585116 | CCAAT/enhancer-binding protein gamma-like. (257 aa) |
| | LOC110582885 | Cathepsin E-like. (174 aa) |
| | RAF1 | RAF proto-oncogene serine/threonine-protein kinase. (648 aa) |
| | JAK2 | Tyrosine-protein kinase. (1130 aa) |
| | CASP3 | Caspase-3 isoform X1; Belongs to the peptidase C14A family. (302 aa) |
| | LOC110580890 | C-type lectin domain family 4 member E-like. (219 aa) |
| | ATP6V0A4 | V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (840 aa) |
| | IFITM10 | Interferon-induced transmembrane protein 10. (176 aa) |
| | NFYA | Nuclear transcription factor Y subunit alpha. (347 aa) |
| | BCL10 | B-cell lymphoma/leukemia 10 isoform X1. (233 aa) |
| | TLR4 | Toll-like receptor 4; Belongs to the Toll-like receptor family. (833 aa) |
| | PPP3R2 | Calcineurin subunit B type 2. (170 aa) |
| | LOC110579961 | Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | CARD9 | Caspase recruitment domain-containing protein 9. (547 aa) |
| | BPI | Bactericidal permeability-increasing protein. (483 aa) |
| | CLEC7A | C-type lectin domain family 7 member A isoform X1. (248 aa) |
| | CASP9 | Caspase-9; Belongs to the peptidase C14A family. (447 aa) |
| | ATP6V0D2 | V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family. (351 aa) |
| | FADD | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (218 aa) |
| | TCIRG1 | V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (846 aa) |
| | CORO1B | Coronin; Belongs to the WD repeat coronin family. (489 aa) |
| | RELA | Transcription factor p65. (531 aa) |
| | MAPK14 | Mitogen-activated protein kinase. (360 aa) |
| | MAPK13 | Mitogen-activated protein kinase. (365 aa) |
| | LOC110575559 | HLA class II histocompatibility antigen, DQ beta 1 chain-like. (269 aa) |
| | LOC110575634 | HLA class II histocompatibility antigen, DO alpha chain; Belongs to the MHC class II family. (291 aa) |
| | LOC110575557 | HLA class II histocompatibility antigen, DQ alpha 2 chain-like; Belongs to the MHC class II family. (255 aa) |
| | LOC110575560 | HLA class II histocompatibility antigen, DO beta chain. (273 aa) |
| | CALML6 | Calmodulin-like protein 6. (232 aa) |
| | FCER1G | High affinity immunoglobulin epsilon receptor subunit gamma. (86 aa) |
| | IRAK1 | Interleukin-1 receptor-associated kinase 1. (726 aa) |
| | ATP6AP1 | V-type proton ATPase subunit S1. (464 aa) |
| | RFXANK | DNA-binding protein RFXANK isoform X1. (260 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | IL10 | Interleukin-10. (178 aa) |
| | SPHK1 | Sphingosine kinase 1 isoform X1. (487 aa) |
| | ATP6V0A1 | V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (832 aa) |
| | RAB5C | Ras-related protein Rab-5C. (216 aa) |
| | NFKB1 | Nuclear factor NF-kappa-B p105 subunit isoform X4. (987 aa) |
| | SPHK2 | Sphingosine kinase 2. (656 aa) |
| | JAK1 | Tyrosine-protein kinase. (1156 aa) |
| | BAX | Apoptosis regulator BAX isoform X1. (192 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) |
| | LOC110572425 | Parvalbumin beta-like. (129 aa) |
| | PPP3CA | Serine/threonine-protein phosphatase. (526 aa) |
| | CALM1 | Calmodulin-1; Belongs to the calmodulin family. (149 aa) |
| | TGFB3 | Transforming growth factor beta-3. (461 aa) |
| | ITGB2 | Integrin beta. (453 aa) |
| | EFCAB13 | LOW QUALITY PROTEIN: EF-hand calcium-binding domain-containing protein 13. (906 aa) |
| | RAB5A | Ras-related protein Rab-5A. (215 aa) |
| | RAB17 | LOW QUALITY PROTEIN: ras-related protein Rab-17. (161 aa) |
| | IFNGR2 | Interferon gamma receptor 2 isoform X1. (356 aa) |
| | IFNG | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (166 aa) |
| | EFCAB3 | EF-hand calcium-binding domain-containing protein 3 isoform X1. (646 aa) |
| | MRC2 | C-type mannose receptor 2. (1378 aa) |
| | RFXAP | Regulatory factor X-associated protein. (287 aa) |
| | IL10RB | Interleukin-10 receptor subunit beta. (375 aa) |
