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| | GRB2 | Growth factor receptor-bound protein 2. (217 aa) |
| | TICAM1 | TIR domain-containing adapter molecule 1; Involved in innate immunity against invading pathogens. Component of a multi-helicase-TICAM1 complex that acts as a cytoplasmic sensor of viral double-stranded RNA (dsRNA) and plays a role in the activation of a cascade of antiviral responses including the induction of proinflammatory cytokines. (767 aa) |
| | YWHAE | 14-3-3 protein epsilon; Belongs to the 14-3-3 family. (255 aa) |
| | LDLR | Low-density lipoprotein receptor. (861 aa) |
| | MAP2K2 | Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa) |
| | TYK2 | Tyrosine-protein kinase. (1189 aa) |
| | CXCL10 | C-X-C motif chemokine. (98 aa) |
| | CASP8 | LOW QUALITY PROTEIN: caspase-8; Belongs to the peptidase C14A family. (486 aa) |
| | PPP2CA | Serine/threonine-protein phosphatase. (309 aa) |
| | TRADD | Tumor necrosis factor receptor type 1-associated DEATH domain protein isoform X1. (312 aa) |
| | EGFR | Receptor protein-tyrosine kinase. (1207 aa) |
| | YWHAH | 14-3-3 protein eta; Belongs to the 14-3-3 family. (246 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) |
| | CFLAR | CASP8 and FADD-like apoptosis regulator; Belongs to the peptidase C14A family. (482 aa) |
| | STAT1 | Signal transducer and activator of transcription. (750 aa) |
| | LOC110592054 | Cytochrome c, testis-specific; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | CLDN4 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (209 aa) |
| | CLDN11 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (207 aa) |
| | PPP2R2B | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (446 aa) |
| | YWHAG | 14-3-3 protein gamma; Belongs to the 14-3-3 family. (247 aa) |
| | PIK3R1 | Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (725 aa) |
| | LOC110589308 | Interferon-induced protein with tetratricopeptide repeats 5. (482 aa) |
| | SOS2 | Son of sevenless homolog 2 isoform X1. (1338 aa) |
| | SCARB1 | Scavenger receptor class B member 1; Belongs to the CD36 family. (509 aa) |
| | CLDN3 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (218 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa) |
| | OCLN | Occludin; May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. Belongs to the ELL/occludin family. (521 aa) |
| | CLDN6 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (221 aa) |
| | CHUK | Inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1. (744 aa) |
| | IFNA5 | LOW QUALITY PROTEIN: interferon alpha-5. (187 aa) |
| | SOS1 | Son of sevenless homolog 1. (1333 aa) |
| | LOC110587131 | Interferon alpha-16-like. (182 aa) |
| | E2F3 | Transcription factor E2F3 isoform X1. (466 aa) |
| | PPP2R2A | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (447 aa) |
| | OAS2 | 2'-5'-oligoadenylate synthase 2. (685 aa) |
| | OAS3 | LOW QUALITY PROTEIN: 2'-5'-oligoadenylate synthase 3. (1089 aa) |
| | OAS1 | 2'-5'-oligoadenylate synthase 1. (444 aa) |
| | CLDN25 | Putative claudin-25. (228 aa) |
| | LOC110586047 | Interferon-induced protein with tetratricopeptide repeats 3-like isoform X1. (499 aa) |
| | CLDN9 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (217 aa) |
| | LOC110586048 | Interferon-induced protein with tetratricopeptide repeats 1B-like isoform X1. (501 aa) |
| | CLDN10 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (231 aa) |
| | IRF9 | Interferon regulatory factor 9. (410 aa) |
| | YWHAQ | 14-3-3 protein theta; Belongs to the 14-3-3 family. (245 aa) |
| | RSAD2 | Radical S-adenosyl methionine domain-containing protein 2. (363 aa) |
| | NFKBIA | NF-kappa-B inhibitor alpha. (314 aa) |
| | EIF2AK2 | Interferon-induced, double-stranded RNA-activated protein kinase. (541 aa) |
| | EIF2AK3 | Eukaryotic translation initiation factor 2-alpha kinase 3. (1114 aa) |
| | IFNB1 | Interferon beta. (182 aa) |
| | TNF | Tumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa) |
| | RIPK1 | Receptor-interacting serine/threonine-protein kinase 1. (665 aa) |
| | CLDN7 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa) |
| | CLDN23 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (291 aa) |
| | LOC110584232 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (217 aa) |
| | TLR3 | Toll-like receptor 3; Belongs to the Toll-like receptor family. (905 aa) |
| | PPP2R1B | Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform isoform X2. (693 aa) |
| | LOC110586049 | Interferon-induced protein with tetratricopeptide repeats 1-like. (480 aa) |
| | FAS | Tumor necrosis factor receptor superfamily member 6. (314 aa) |
| | PIAS1 | E3 SUMO-protein ligase PIAS1. (651 aa) |
| | EIF2AK4 | eIF-2-alpha kinase GCN2. (1653 aa) |
| | RAF1 | RAF proto-oncogene serine/threonine-protein kinase. (648 aa) |
| | CLDN16 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (384 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (381 aa) |
| | LOC110584242 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (220 aa) |
| | IRF7 | Interferon regulatory factor 7. (496 aa) |
| | PPP2CB | Serine/threonine-protein phosphatase. (309 aa) |
| | CASP3 | Caspase-3 isoform X1; Belongs to the peptidase C14A family. (302 aa) |
| | MAP2K1 | Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa) |
| | DDX58 | Probable ATP-dependent RNA helicase DDX58. (995 aa) |
| | CLDN20 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (219 aa) |
| | CLDN5 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (309 aa) |
| | BRAF | Serine/threonine-protein kinase B-raf. (764 aa) |
| | GSK3B | Glycogen synthase kinase-3 beta isoform X1; Belongs to the protein kinase superfamily. (433 aa) |
| | LOC110582476 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (155 aa) |
| | CLDN1 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
| | HRAS | GTPase HRas isoform X1. (189 aa) |
| | NRAS | GTPase NRas. (189 aa) |
| | E2F1 | LOW QUALITY PROTEIN: transcription factor E2F1. (483 aa) |
| | RXRA | Retinoic acid receptor RXR-alpha. (413 aa) |
| | MAVS | Mitochondrial antiviral-signaling protein isoform X1. (547 aa) |
| | LOC110579961 | Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | TRAF2 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (523 aa) |
| | CLDN17 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (224 aa) |
| | TNFRSF1A | Tumor necrosis factor receptor superfamily member 1A. (451 aa) |
| | KRAS | GTPase KRas. (188 aa) |
| | BID | BH3-interacting domain death agonist; Counters the protective effect of Bcl-2. (240 aa) |
| | CSDE1 | Cold shock domain-containing protein E1 isoform X1. (798 aa) |
| | CUNH7orf31 | Uncharacterized protein C7orf31 homolog. (590 aa) |
| | CDK6 | Cyclin-dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa) |
| | RB1 | Retinoblastoma-associated protein. (934 aa) |
| | MAPK1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (361 aa) |
| | YWHAB | 14-3-3 protein beta/alpha; Belongs to the 14-3-3 family. (244 aa) |
| | EIF3E | Eukaryotic translation initiation factor 3 subunit E; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (445 aa) |
| | YWHAZ | 14-3-3 protein zeta/delta; Belongs to the 14-3-3 family. (245 aa) |
| | MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (438 aa) |
| | CCND1 | G1/S-specific cyclin-D1; Belongs to the cyclin family. (295 aa) |
| | APAF1 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1250 aa) |
| | PPARA | Peroxisome proliferator-activated receptor alpha. (468 aa) |
| | TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (541 aa) |
| | STAT2 | Signal transducer and activator of transcription. (854 aa) |
| | CDK4 | Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa) |
| | CDK2 | Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily. (298 aa) |
| | BAD | Bcl2-associated agonist of cell death isoform X1. (205 aa) |
| | IKBKE | Inhibitor of nuclear factor kappa-B kinase subunit epsilon isoform X1. (774 aa) |
| | PPP1R14B | LOW QUALITY PROTEIN: protein phosphatase 1 regulatory subunit 14B-like. (203 aa) |
| | NR1H3 | Oxysterols receptor LXR-alpha isoform X1. (447 aa) |
| | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa) |
| | PIK3R3 | Phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1. (507 aa) |
| | CD81 | Tetraspanin. (165 aa) |
| | CASP9 | Caspase-9; Belongs to the peptidase C14A family. (447 aa) |
| | FADD | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (218 aa) |
| | RELA | Transcription factor p65. (531 aa) |
| | CDKN1A | Cyclin-dependent kinase inhibitor 1. (161 aa) |
| | RNASEL | LOW QUALITY PROTEIN: 2-5A-dependent ribonuclease. (730 aa) |
| | BAK1 | Bcl-2 homologous antagonist/killer. (211 aa) |
| | EGF | Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1197 aa) |
| | FASLG | Tumor necrosis factor ligand superfamily member 6 isoform X1; Belongs to the tumor necrosis factor family. (281 aa) |
| | CLDN19 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (224 aa) |
| | E2F2 | Transcription factor E2F2. (449 aa) |
| | STAT3 | Signal transducer and activator of transcription. (770 aa) |
| | PIK3R2 | Phosphatidylinositol 3-kinase regulatory subunit beta isoform X1. (726 aa) |
| | PSME3 | Proteasome activator complex subunit 3. (254 aa) |
| | IKBKG | NF-kappa-B essential modulator. (419 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | IRF3 | Interferon regulatory factor 3 isoform X1. (458 aa) |
| | IKBKB | Inhibitor of nuclear factor kappa-B kinase subunit beta. (756 aa) |
| | PPP2R1A | Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform isoform X1. (589 aa) |
| | NFKB1 | Nuclear factor NF-kappa-B p105 subunit isoform X4. (987 aa) |
| | JAK1 | Tyrosine-protein kinase. (1156 aa) |
| | BAX | Apoptosis regulator BAX isoform X1. (192 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) |
| | EIF2AK1 | Eukaryotic translation initiation factor 2-alpha kinase 1 isoform X1. (630 aa) |
| | SOCS3 | Suppressor of cytokine signaling 3. (225 aa) |
| | EIF2S1 | Eukaryotic translation initiation factor 2 subunit 1. (315 aa) |
| | ARAF | Serine/threonine-protein kinase A-Raf. (606 aa) |
| | MX2 | Interferon-induced GTP-binding protein Mx2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (712 aa) |
| | TRAF3 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (568 aa) |
| | PIK3CB | LOW QUALITY PROTEIN: phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform; Belongs to the PI3/PI4-kinase family. (1070 aa) |
| | IFNAR2 | Interferon alpha/beta receptor 2 isoform X1. (516 aa) |
| | MX1 | Interferon-induced GTP-binding protein Mx1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (660 aa) |
| | ERAS | GTPase ERas. (233 aa) |
| | PPP2R2C | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (447 aa) |
| | CLDN18 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (261 aa) |
| | TBK1 | Serine/threonine-protein kinase TBK1 isoform X1. (729 aa) |
| | IFNG | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (166 aa) |
| | CTNNB1 | Catenin beta-1. (781 aa) |
| | CLDN2 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (230 aa) |
| | CLDN8 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (225 aa) |
| | IFNAR1 | Interferon alpha/beta receptor 1. (560 aa) |
| | CLDN14 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (237 aa) |
| | CLDN34 | Claudin-34. (215 aa) |
