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| | LOC110586231 | Caspase-12-like; Belongs to the peptidase C14A family. (389 aa) |
| | TLR3 | Toll-like receptor 3; Belongs to the Toll-like receptor family. (905 aa) |
| | FAS | Tumor necrosis factor receptor superfamily member 6. (314 aa) |
| | SMAD3 | Mothers against decapentaplegic homolog. (425 aa) |
| | NFATC4 | Nuclear factor of activated T-cells, cytoplasmic 4. (902 aa) |
| | RAF1 | RAF proto-oncogene serine/threonine-protein kinase. (648 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (381 aa) |
| | JAK2 | Tyrosine-protein kinase. (1130 aa) |
| | MAP2K3 | Dual specificity mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (347 aa) |
| | IRF7 | Interferon regulatory factor 7. (496 aa) |
| | CASP3 | Caspase-3 isoform X1; Belongs to the peptidase C14A family. (302 aa) |
| | MAP2K1 | Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa) |
| | TGFBR1 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa) |
| | MAP3K7 | Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa) |
| | DDX58 | Probable ATP-dependent RNA helicase DDX58. (995 aa) |
| | TAB2 | TGF-beta-activated kinase 1 and MAP3K7-binding protein 2. (693 aa) |
| | CREB3L2 | Cyclic AMP-responsive element-binding protein 3-like protein 2. (520 aa) |
| | BRAF | Serine/threonine-protein kinase B-raf. (764 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
| | HRAS | GTPase HRas isoform X1. (189 aa) |
| | NRAS | GTPase NRas. (189 aa) |
| | E2F1 | LOW QUALITY PROTEIN: transcription factor E2F1. (483 aa) |
| | TLR4 | Toll-like receptor 4; Belongs to the Toll-like receptor family. (833 aa) |
| | MAVS | Mitochondrial antiviral-signaling protein isoform X1. (547 aa) |
| | LOC110579961 | Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | CREB3 | Cyclic AMP-responsive element-binding protein 3 isoform X2. (352 aa) |
| | LOC110581163 | ATP-dependent RNA helicase DDX3X-like; Belongs to the DEAD box helicase family. (662 aa) |
| | LOC110579526 | Signal transducer and activator of transcription 5A-like. (153 aa) |
| | KRAS | GTPase KRas. (188 aa) |
| | BID | BH3-interacting domain death agonist; Counters the protective effect of Bcl-2. (240 aa) |
| | CSDE1 | Cold shock domain-containing protein E1 isoform X1. (798 aa) |
| | NFATC1 | Nuclear factor of activated T-cells, cytoplasmic 1 isoform X1. (891 aa) |
| | APAF1 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1250 aa) |
| | TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (541 aa) |
| | STAT2 | Signal transducer and activator of transcription. (854 aa) |
| | CDK2 | Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily. (298 aa) |
| | BAD | Bcl2-associated agonist of cell death isoform X1. (205 aa) |
| | IKBKE | Inhibitor of nuclear factor kappa-B kinase subunit epsilon isoform X1. (774 aa) |
| | PPP1R14B | LOW QUALITY PROTEIN: protein phosphatase 1 regulatory subunit 14B-like. (203 aa) |
| | BCL2 | Apoptosis regulator Bcl-2 isoform X1. (234 aa) |
| | SMAD4 | Mothers against decapentaplegic homolog. (552 aa) |
| | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa) |
| | NFATC2 | Nuclear factor of activated T-cells, cytoplasmic 2. (920 aa) |
| | PIK3R3 | Phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1. (507 aa) |
| | DDB1 | DNA damage-binding protein 1. (1140 aa) |
| | CASP9 | Caspase-9; Belongs to the peptidase C14A family. (447 aa) |
| | FADD | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (218 aa) |
| | JAK3 | Tyrosine-protein kinase. (1104 aa) |
| | RELA | Transcription factor p65. (531 aa) |
| | CREB3L1 | Cyclic AMP-responsive element-binding protein 3-like protein 1. (520 aa) |
| | DDB2 | DNA damage-binding protein 2. (412 aa) |
| | CDKN1A | Cyclin-dependent kinase inhibitor 1. (161 aa) |
| | MAPK14 | Mitogen-activated protein kinase. (360 aa) |
| | MAPK13 | Mitogen-activated protein kinase. (365 aa) |
| | FASLG | Tumor necrosis factor ligand superfamily member 6 isoform X1; Belongs to the tumor necrosis factor family. (281 aa) |
| | HSPG2 | Basement membrane-specific heparan sulfate proteoglycan core protein. (4777 aa) |
| | PRKCG | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa) |
| | JUN | Transcription factor AP-1 isoform X1; Belongs to the bZIP family. (335 aa) |
| | E2F2 | Transcription factor E2F2. (449 aa) |
| | STAT3 | Signal transducer and activator of transcription. (770 aa) |
| | PIK3R2 | Phosphatidylinositol 3-kinase regulatory subunit beta isoform X1. (726 aa) |
| | IRAK1 | Interleukin-1 receptor-associated kinase 1. (726 aa) |
| | ATP6AP1 | V-type proton ATPase subunit S1. (464 aa) |
| | LOC110573272 | Signal transducer and activator of transcription 5A. (478 aa) |
| | IKBKG | NF-kappa-B essential modulator. (419 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | IRF3 | Interferon regulatory factor 3 isoform X1. (458 aa) |
| | GRB2 | Growth factor receptor-bound protein 2. (217 aa) |
| | CREB3L4 | Cyclic AMP-responsive element-binding protein 3-like protein 4 isoform X2. (394 aa) |
| | DDX3X | ATP-dependent RNA helicase DDX3X isoform X1; Belongs to the DEAD box helicase family. (662 aa) |
| | LOC110573273 | Signal transducer and activator of transcription 5B. (600 aa) |
| | VDAC3 | Voltage-dependent anion-selective channel protein 3 isoform X1. (283 aa) |
| | IKBKB | Inhibitor of nuclear factor kappa-B kinase subunit beta. (756 aa) |
| | CCNA2 | cyclin-A2; Belongs to the cyclin family. (432 aa) |
| | NFKB1 | Nuclear factor NF-kappa-B p105 subunit isoform X4. (987 aa) |
| | JAK1 | Tyrosine-protein kinase. (1156 aa) |
| | BAX | Apoptosis regulator BAX isoform X1. (192 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) |
| | BIRC5 | Baculoviral IAP repeat-containing protein 5. (142 aa) |
| | ELK1 | ETS domain-containing protein Elk-1 isoform X1. (435 aa) |
| | ARAF | Serine/threonine-protein kinase A-Raf. (606 aa) |
| | TGFBR2 | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (567 aa) |
| | SLC10A1 | Sodium/bile acid cotransporter. (385 aa) |
| | TRAF3 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (568 aa) |
| | PIK3CB | LOW QUALITY PROTEIN: phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform; Belongs to the PI3/PI4-kinase family. (1070 aa) |
| | FOS | Proto-oncogene c-Fos. (380 aa) |
| | TGFB3 | Transforming growth factor beta-3. (461 aa) |
| | PRKCA | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa) |
| | ERAS | GTPase ERas. (233 aa) |
| | TBK1 | Serine/threonine-protein kinase TBK1 isoform X1. (729 aa) |
| | MAP2K6 | Dual specificity mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa) |
| | CCNA1 | cyclin-A1; Belongs to the cyclin family. (421 aa) |
| | MAPK9 | Mitogen-activated protein kinase. (424 aa) |
| | MAP2K7 | Dual specificity mitogen-activated protein kinase kinase 7 isoform X1. (440 aa) |
| | TICAM1 | TIR domain-containing adapter molecule 1; Involved in innate immunity against invading pathogens. Component of a multi-helicase-TICAM1 complex that acts as a cytoplasmic sensor of viral double-stranded RNA (dsRNA) and plays a role in the activation of a cascade of antiviral responses including the induction of proinflammatory cytokines. (767 aa) |
| | NFATC3 | Nuclear factor of activated T-cells, cytoplasmic 3 isoform X1. (1075 aa) |
| | ATF2 | Cyclic AMP-dependent transcription factor ATF-2 isoform X1. (505 aa) |
| | STAT4 | Signal transducer and activator of transcription. (694 aa) |
| | CREB3L3 | Cyclic AMP-responsive element-binding protein 3-like protein 3. (302 aa) |
| | MAP2K2 | Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa) |
| | TYK2 | Tyrosine-protein kinase. (1189 aa) |
| | IRAK4 | Interleukin-1 receptor-associated kinase 4. (460 aa) |
| | CASP8 | LOW QUALITY PROTEIN: caspase-8; Belongs to the peptidase C14A family. (486 aa) |
| | LOC110591311 | Transmembrane emp24 domain-containing protein 7. (224 aa) |
| | CXCL8 | Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (104 aa) |
| | TICAM2 | TIR domain-containing adapter molecule 2. (238 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) |
| | CASP10 | Caspase-10; Belongs to the peptidase C14A family. (481 aa) |
| | CREB1 | Cyclic AMP-responsive element-binding protein 1. (327 aa) |
| | STAT1 | Signal transducer and activator of transcription. (750 aa) |
| | LOC110592054 | Cytochrome c, testis-specific; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | IFIH1 | Interferon-induced helicase C domain-containing protein 1. (1026 aa) |
| | LOC110591392 | Mitogen-activated protein kinase. (300 aa) |
| | IFNAR1 | Interferon alpha/beta receptor 1. (560 aa) |
| | MYD88 | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (321 aa) |
| | LOC110591391 | Mitogen-activated protein kinase 10-like. (176 aa) |
| | PIK3R1 | Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (725 aa) |
| | CREB5 | Cyclic AMP-responsive element-binding protein 5. (501 aa) |
| | CUNH7orf31 | Uncharacterized protein C7orf31 homolog. (590 aa) |
| | IL6 | Interleukin-6 isoform X1. (212 aa) |
| | LOC110579958 | Signal transducer and activator of transcription 5B-like. (204 aa) |
| | TAB1 | TGF-beta-activated kinase 1 and MAP3K7-binding protein 1. (504 aa) |
| | MAP3K1 | Mitogen-activated protein kinase kinase kinase 1. (1393 aa) |
| | EGR2 | E3 SUMO-protein ligase EGR2 isoform X1. (484 aa) |
| | SOS2 | Son of sevenless homolog 2 isoform X1. (1338 aa) |
| | CCNE1 | G1/S-specific cyclin-E1 isoform X1; Belongs to the cyclin family. (410 aa) |
| | LOC110588386 | LOW QUALITY PROTEIN: toll-like receptor 2. (348 aa) |
| | TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa) |
| | RB1 | Retinoblastoma-associated protein. (934 aa) |
| | MAPK1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (361 aa) |
| | MAPK11 | Mitogen-activated protein kinase. (364 aa) |
| | SRC | Tyrosine-protein kinase. (536 aa) |
| | ATF4 | Cyclic AMP-dependent transcription factor ATF-4. (351 aa) |
| | MMP9 | Matrix metalloproteinase-9 isoform X1. (704 aa) |
| | PCNA | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa) |
| | YWHAB | 14-3-3 protein beta/alpha; Belongs to the 14-3-3 family. (244 aa) |
| | EP300 | Histone acetyltransferase p300. (2420 aa) |
| | PRKCB | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (634 aa) |
| | CCNE2 | G1/S-specific cyclin-E2; Belongs to the cyclin family. (404 aa) |
| | STAT6 | Signal transducer and activator of transcription. (844 aa) |
| | YWHAZ | 14-3-3 protein zeta/delta; Belongs to the 14-3-3 family. (245 aa) |
| | MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (438 aa) |
| | MAPK12 | Mitogen-activated protein kinase. (367 aa) |
| | EGR3 | Early growth response protein 3. (387 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa) |
| | MAPK8 | Mitogen-activated protein kinase. (427 aa) |
| | TGFB2 | Transforming growth factor beta; Belongs to the TGF-beta family. (414 aa) |
| | CHUK | Inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1. (744 aa) |
| | IFNA5 | LOW QUALITY PROTEIN: interferon alpha-5. (187 aa) |
| | ATF6B | Cyclic AMP-dependent transcription factor ATF-6 beta isoform X1. (711 aa) |
| | SOS1 | Son of sevenless homolog 1. (1333 aa) |
| | LOC110587131 | Interferon alpha-16-like. (182 aa) |
| | PTK2B | Protein-tyrosine kinase 2-beta isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1010 aa) |
| | E2F3 | Transcription factor E2F3 isoform X1. (466 aa) |
| | TLR2 | Toll-like receptor 2; Belongs to the Toll-like receptor family. (785 aa) |
| | TIRAP | Toll/interleukin-1 receptor domain-containing adapter protein. (223 aa) |
| | CREBBP | CREB-binding protein isoform X3. (2433 aa) |
| | YWHAQ | 14-3-3 protein theta; Belongs to the 14-3-3 family. (245 aa) |
| | NFKBIA | NF-kappa-B inhibitor alpha. (314 aa) |
| | IFNB1 | Interferon beta. (182 aa) |
| | TNF | Tumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa) |
| | MAP2K4 | Dual specificity mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (400 aa) |
