STRINGSTRING
LOC110592974 LOC110592974 GNG14 GNG14 GNA11 GNA11 PTGER1 PTGER1 GNG7 GNG7 CRK CRK PXN PXN CX3CL1 CX3CL1 NFATC3 NFATC3 ATF2 ATF2 ITGAV ITGAV GNAO1 GNAO1 PRKACA PRKACA RPS6KB1 RPS6KB1 CREB3L3 CREB3L3 ADCY1 ADCY1 CALR CALR ADCY6 ADCY6 RHEBL1 RHEBL1 MAP2K2 MAP2K2 ADCY7 ADCY7 CASP8 CASP8 LOC110593301 LOC110593301 BCAR1 BCAR1 GNGT2 GNGT2 CCL5 CCL5 LOC110593029 LOC110593029 TRADD TRADD EGFR EGFR CXCL8 CXCL8 PDGFRA PDGFRA LOC110592210 LOC110592210 AKT2 AKT2 CREB1 CREB1 LOC110591944 LOC110591944 LOC110592156 LOC110592156 RUFY4 RUFY4 LOC110592054 LOC110592054 CXCL12 CXCL12 ADCY2 ADCY2 PIK3R1 PIK3R1 PPP3CB PPP3CB TMEM173 TMEM173 PTGER2 PTGER2 GNG2 GNG2 PPP3R1 PPP3R1 SOS2 SOS2 MAPK3 MAPK3 ADCY9 ADCY9 PTRHD1 PTRHD1 CHUK CHUK IFNA5 IFNA5 ATF6B ATF6B SOS1 SOS1 LOC110587131 LOC110587131 PPP3CC PPP3CC PTK2B PTK2B E2F3 E2F3 ARHGEF12 ARHGEF12 TSC2 TSC2 GNG13 GNG13 CXCR4 CXCR4 ROCK2 ROCK2 PDIA3 PDIA3 NFKBIA NFKBIA B2M B2M ADCY3 ADCY3 IL1B IL1B IFNB1 IFNB1 LOC110586919 LOC110586919 TNF TNF RIPK1 RIPK1 LOC110586587 LOC110586587 CALML5 CALML5 IL10RA IL10RA PTGER4 PTGER4 FAS FAS GNG4 GNG4 CALML4 CALML4 ADCY4 ADCY4 PLCB2 PLCB2 NFATC4 NFATC4 RAF1 RAF1 RHEB RHEB ITPR1 ITPR1 TP53 TP53 CASP3 CASP3 GNB5 GNB5 MAP2K1 MAP2K1 VEGFA VEGFA MB21D1 MB21D1 CREB3L2 CREB3L2 PRKACB PRKACB GSK3B GSK3B ADCY5 ADCY5 GNB4 GNB4 PIK3CA PIK3CA ARHGEF1 ARHGEF1 HRAS HRAS GNG5 GNG5 GNGT1 GNGT1 NRAS NRAS E2F1 E2F1 LOC110581611 LOC110581611 GNG11 GNG11 PPP3R2 PPP3R2 LOC110579961 LOC110579961 TSC1 TSC1 CREB3 CREB3 GNG10 GNG10 PLCB1 PLCB1 LOC110579709 LOC110579709 TRAF2 TRAF2 ADCY8 ADCY8 GNB3 GNB3 ITPR2 ITPR2 TNFRSF1A TNFRSF1A KRAS KRAS PTK2 PTK2 BID BID GNAI3 GNAI3 CSDE1 CSDE1 LOC110580263 LOC110580263 CREB5 CREB5 CUNH7orf31 CUNH7orf31 IL6 IL6 GNAI1 GNAI1 CDK6 CDK6 RB1 RB1 MAPK1 MAPK1 MAPK11 MAPK11 SRC SRC ATF4 ATF4 RAC2 RAC2 PLCB4 PLCB4 PRKCB PRKCB SP1 SP1 MYC MYC CRKL CRKL MAPK12 MAPK12 CCND1 CCND1 NFATC1 NFATC1 CDK4 CDK4 GNG3 GNG3 GNAI2 GNAI2 TAP2 TAP2 ROCK1 ROCK1 PIK3CD PIK3CD NFATC2 NFATC2 PIK3R3 PIK3R3 MTOR MTOR CASP9 CASP9 GNB1 GNB1 FADD FADD RPS6KB2 RPS6KB2 RELA RELA PLCB3 PLCB3 LPXN LPXN CREB3L1 CREB3L1 LOC110575688 LOC110575688 ITPR3 ITPR3 CDKN1A CDKN1A MAPK14 MAPK14 MAPK13 MAPK13 TAP1 TAP1 BAK1 BAK1 TAPBP TAPBP FASLG FASLG PTGS2 PTGS2 CALML6 CALML6 PRKCG PRKCG TRAF5 TRAF5 E2F2 E2F2 STAT3 STAT3 PIK3R2 PIK3R2 EIF4EBP1 EIF4EBP1 CCR3 CCR3 LOC110574374 LOC110574374 LOC110574370 LOC110574370 IKBKG IKBKG AKT3 AKT3 IRF3 IRF3 ARHGEF11 ARHGEF11 GRB2 GRB2 CREB3L4 CREB3L4 IL6R IL6R IL1R1 IL1R1 IKBKB IKBKB GNA12 GNA12 NFKB1 NFKB1 GNG12 GNG12 JAK1 JAK1 BAX BAX AKT1 AKT1 GNG8 GNG8 ELK1 ELK1 LOC110572425 LOC110572425 RAC3 RAC3 AKAP13 AKAP13 PPP3CA PPP3CA RAC1 RAC1 GNB2 GNB2 CALM1 CALM1 PIK3CB PIK3CB MDM2 MDM2 PRKCA PRKCA ERAS ERAS TBK1 TBK1 MAP2K6 MAP2K6 GNA13 GNA13 CTNNB1 CTNNB1 ITGB3 ITGB3 PTGER3 PTGER3 IL10RB IL10RB LOC110569839 LOC110569839 GNAS GNAS
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC110592974C-C motif chemokine. (101 aa)
GNG14LOW QUALITY PROTEIN: uncharacterized LOC105372280 homolog. (100 aa)
GNA11Guanine nucleotide-binding protein subunit alpha-11. (359 aa)
PTGER1Prostaglandin E2 receptor EP1 subtype. (402 aa)
GNG7Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
CRKAdapter molecule crk isoform X1. (304 aa)
PXNPaxillin isoform X1; Belongs to the paxillin family. (599 aa)
CX3CL1Fractalkine. (436 aa)
NFATC3Nuclear factor of activated T-cells, cytoplasmic 3 isoform X1. (1075 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2 isoform X1. (505 aa)
ITGAVIntegrin alpha-V isoform X1; Belongs to the integrin alpha chain family. (1047 aa)
GNAO1Guanine nucleotide-binding protein G(O) subunit alpha. (354 aa)
PRKACAcAMP-dependent protein kinase catalytic subunit alpha; Belongs to the protein kinase superfamily. (351 aa)
RPS6KB1Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa)
CREB3L3Cyclic AMP-responsive element-binding protein 3-like protein 3. (302 aa)
ADCY1Adenylate cyclase type 1. (921 aa)
CALRCalreticulin. (417 aa)
ADCY6Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1161 aa)
RHEBL1GTPase RhebL1. (183 aa)
MAP2K2Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa)
ADCY7Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1075 aa)
CASP8LOW QUALITY PROTEIN: caspase-8; Belongs to the peptidase C14A family. (486 aa)
LOC110593301Regakine-1-like. (94 aa)
BCAR1Breast cancer anti-estrogen resistance protein 1. (865 aa)
GNGT2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (118 aa)
CCL5C-C motif chemokine. (91 aa)
LOC110593029C-C motif chemokine. (93 aa)
TRADDTumor necrosis factor receptor type 1-associated DEATH domain protein isoform X1. (312 aa)
EGFRReceptor protein-tyrosine kinase. (1207 aa)
CXCL8Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (104 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1089 aa)
LOC110592210Calmodulin-like; Belongs to the calmodulin family. (149 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
CREB1Cyclic AMP-responsive element-binding protein 1. (327 aa)
LOC110591944C-X-C chemokine receptor type 2; Belongs to the G-protein coupled receptor 1 family. (356 aa)
LOC110592156Calmodulin-like; Belongs to the calmodulin family. (98 aa)
RUFY4RUN and FYVE domain-containing protein 4. (609 aa)
LOC110592054Cytochrome c, testis-specific; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
CXCL12Stromal cell-derived factor 1 isoform X1; Belongs to the intercrine alpha (chemokine CxC) family. (119 aa)
ADCY2Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1091 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (725 aa)
PPP3CBSerine/threonine-protein phosphatase. (527 aa)
TMEM173Stimulator of interferon genes protein. (378 aa)
PTGER2Prostaglandin E2 receptor EP2 subtype; Belongs to the G-protein coupled receptor 1 family. (353 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (71 aa)
PPP3R1Calcineurin subunit B type 1. (170 aa)
SOS2Son of sevenless homolog 2 isoform X1. (1338 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
ADCY9Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1352 aa)
PTRHD1Putative peptidyl-tRNA hydrolase PTRHD1. (140 aa)
CHUKInhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1. (744 aa)
IFNA5LOW QUALITY PROTEIN: interferon alpha-5. (187 aa)
ATF6BCyclic AMP-dependent transcription factor ATF-6 beta isoform X1. (711 aa)
SOS1Son of sevenless homolog 1. (1333 aa)
LOC110587131Interferon alpha-16-like. (182 aa)
PPP3CCSerine/threonine-protein phosphatase. (525 aa)
PTK2BProtein-tyrosine kinase 2-beta isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1010 aa)
E2F3Transcription factor E2F3 isoform X1. (466 aa)
ARHGEF12Rho guanine nucleotide exchange factor 12 isoform X1. (1543 aa)
TSC2Tuberin isoform X1. (1789 aa)
GNG13Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13. (67 aa)
CXCR4C-X-C chemokine receptor type 4; Belongs to the G-protein coupled receptor 1 family. (353 aa)
ROCK2Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1391 aa)
PDIA3Protein disulfide-isomerase. (505 aa)
NFKBIANF-kappa-B inhibitor alpha. (314 aa)
B2MBeta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. (118 aa)
ADCY3Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1145 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (270 aa)
IFNB1Interferon beta. (182 aa)
LOC110586919LOW QUALITY PROTEIN: HLA class I histocompatibility antigen, A-3 alpha chain; Belongs to the MHC class I family. (437 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
RIPK1Receptor-interacting serine/threonine-protein kinase 1. (665 aa)
LOC110586587Calmodulin-like protein 3; Belongs to the calmodulin family. (149 aa)
CALML5Calmodulin-like protein 5. (149 aa)
IL10RAInterleukin-10 receptor subunit alpha. (575 aa)
PTGER4Prostaglandin E2 receptor EP4 subtype; Belongs to the G-protein coupled receptor 1 family. (489 aa)
FASTumor necrosis factor receptor superfamily member 6. (314 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
CALML4LOW QUALITY PROTEIN: calmodulin-like protein 4. (197 aa)
ADCY4Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1186 aa)
NFATC4Nuclear factor of activated T-cells, cytoplasmic 4. (902 aa)
RAF1RAF proto-oncogene serine/threonine-protein kinase. (648 aa)
RHEBGTP-binding protein Rheb. (184 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1 isoform X1. (2709 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (381 aa)
CASP3Caspase-3 isoform X1; Belongs to the peptidase C14A family. (302 aa)
GNB5Guanine nucleotide-binding protein subunit beta-5. (395 aa)
MAP2K1Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
VEGFAVascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (549 aa)
MB21D1Cyclic GMP-AMP synthase. (522 aa)
CREB3L2Cyclic AMP-responsive element-binding protein 3-like protein 2. (520 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta; Belongs to the protein kinase superfamily. (397 aa)
GSK3BGlycogen synthase kinase-3 beta isoform X1; Belongs to the protein kinase superfamily. (433 aa)
ADCY5Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1205 aa)
GNB4Guanine nucleotide-binding protein subunit beta-4. (340 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
ARHGEF1Rho guanine nucleotide exchange factor 1 isoform X1. (974 aa)
HRASGTPase HRas isoform X1. (189 aa)
GNG5Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
GNGT1Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
NRASGTPase NRas. (189 aa)
E2F1LOW QUALITY PROTEIN: transcription factor E2F1. (483 aa)
LOC110581611DLA class I histocompatibility antigen, A9/A9 alpha chain-like isoform X1. (188 aa)
GNG11Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
PPP3R2Calcineurin subunit B type 2. (170 aa)
LOC110579961Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
TSC1Hamartin. (1168 aa)
CREB3Cyclic AMP-responsive element-binding protein 3 isoform X2. (352 aa)
GNG10Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
LOC110579709Guanine nucleotide-binding protein G(Q) subunit alpha. (301 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (523 aa)
ADCY8Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1250 aa)
GNB3Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3. (340 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2701 aa)
TNFRSF1ATumor necrosis factor receptor superfamily member 1A. (451 aa)
KRASGTPase KRas. (188 aa)
PTK2Focal adhesion kinase 1 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1055 aa)
BIDBH3-interacting domain death agonist; Counters the protective effect of Bcl-2. (240 aa)
GNAI3Guanine nucleotide-binding protein G(K) subunit alpha. (354 aa)
CSDE1Cold shock domain-containing protein E1 isoform X1. (798 aa)
LOC110580263H-2 class I histocompatibility antigen, Q10 alpha chain-like isoform X1; Belongs to the MHC class I family. (387 aa)
CREB5Cyclic AMP-responsive element-binding protein 5. (501 aa)
CUNH7orf31Uncharacterized protein C7orf31 homolog. (590 aa)
IL6Interleukin-6 isoform X1. (212 aa)
GNAI1Guanine nucleotide-binding protein G(I) subunit alpha-1. (354 aa)
CDK6Cyclin-dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa)
RB1Retinoblastoma-associated protein. (934 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (361 aa)
MAPK11Mitogen-activated protein kinase. (364 aa)
SRCTyrosine-protein kinase. (536 aa)
ATF4Cyclic AMP-dependent transcription factor ATF-4. (351 aa)
RAC2Ras-related C3 botulinum toxin substrate 2 isoform X1. (192 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1194 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (634 aa)
SP1Transcription factor Sp1. (786 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (438 aa)
CRKLCrk-like protein. (303 aa)
MAPK12Mitogen-activated protein kinase. (367 aa)
CCND1G1/S-specific cyclin-D1; Belongs to the cyclin family. (295 aa)
NFATC1Nuclear factor of activated T-cells, cytoplasmic 1 isoform X1. (891 aa)
CDK4Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
GNAI2Guanine nucleotide-binding protein G(I) subunit alpha-2. (355 aa)
TAP2Antigen peptide transporter 2. (703 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1354 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa)
NFATC2Nuclear factor of activated T-cells, cytoplasmic 2. (920 aa)
PIK3R3Phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1. (507 aa)
MTORSerine/threonine-protein kinase mTOR. (2557 aa)
CASP9Caspase-9; Belongs to the peptidase C14A family. (447 aa)
GNB1Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1. (340 aa)
FADDFAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (218 aa)
RPS6KB2Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (483 aa)
RELATranscription factor p65. (531 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1230 aa)
LPXNLeupaxin; Belongs to the paxillin family. (386 aa)
CREB3L1Cyclic AMP-responsive element-binding protein 3-like protein 1. (520 aa)
LOC110575688HLA class I histocompatibility antigen, A-24 alpha chain-like; Belongs to the MHC class I family. (255 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2584 aa)
CDKN1ACyclin-dependent kinase inhibitor 1. (161 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
MAPK13Mitogen-activated protein kinase. (365 aa)
TAP1Antigen peptide transporter 1 isoform X1. (748 aa)
BAK1Bcl-2 homologous antagonist/killer. (211 aa)
TAPBPTapasin isoform X1. (453 aa)
FASLGTumor necrosis factor ligand superfamily member 6 isoform X1; Belongs to the tumor necrosis factor family. (281 aa)
PTGS2Prostaglandin G/H synthase 2. (604 aa)
CALML6Calmodulin-like protein 6. (232 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
TRAF5TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (558 aa)
E2F2Transcription factor E2F2. (449 aa)
STAT3Signal transducer and activator of transcription. (770 aa)
PIK3R2Phosphatidylinositol 3-kinase regulatory subunit beta isoform X1. (726 aa)
EIF4EBP1Eukaryotic translation initiation factor 4E-binding protein 1. (118 aa)
CCR3C-C chemokine receptor type 3; Belongs to the G-protein coupled receptor 1 family. (359 aa)
LOC110574374C-C chemokine receptor type 1-like; Belongs to the G-protein coupled receptor 1 family. (355 aa)
LOC110574370C-C chemokine receptor type 5; Belongs to the G-protein coupled receptor 1 family. (352 aa)
IKBKGNF-kappa-B essential modulator. (419 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
IRF3Interferon regulatory factor 3 isoform X1. (458 aa)
ARHGEF11Rho guanine nucleotide exchange factor 11 isoform X5. (1534 aa)
GRB2Growth factor receptor-bound protein 2. (217 aa)
CREB3L4Cyclic AMP-responsive element-binding protein 3-like protein 4 isoform X2. (394 aa)
IL6RInterleukin-6 receptor subunit alpha. (483 aa)
IL1R1LOW QUALITY PROTEIN: interleukin-1 receptor type 1. (595 aa)
IKBKBInhibitor of nuclear factor kappa-B kinase subunit beta. (756 aa)
GNA12Guanine nucleotide-binding protein subunit alpha-12. (305 aa)
NFKB1Nuclear factor NF-kappa-B p105 subunit isoform X4. (987 aa)
GNG12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
JAK1Tyrosine-protein kinase. (1156 aa)
BAXApoptosis regulator BAX isoform X1. (192 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
GNG8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
ELK1ETS domain-containing protein Elk-1 isoform X1. (435 aa)
LOC110572425Parvalbumin beta-like. (129 aa)
RAC3Ras-related C3 botulinum toxin substrate 3. (195 aa)
AKAP13A-kinase anchor protein 13. (2819 aa)
PPP3CASerine/threonine-protein phosphatase. (526 aa)
RAC1Ras-related C3 botulinum toxin substrate 1 isoform X1. (211 aa)
GNB2Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2. (340 aa)
CALM1Calmodulin-1; Belongs to the calmodulin family. (149 aa)
PIK3CBLOW QUALITY PROTEIN: phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform; Belongs to the PI3/PI4-kinase family. (1070 aa)
MDM2E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (487 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
ERASGTPase ERas. (233 aa)
TBK1Serine/threonine-protein kinase TBK1 isoform X1. (729 aa)
MAP2K6Dual specificity mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa)
GNA13Guanine nucleotide-binding protein subunit alpha-13 isoform X1. (377 aa)
CTNNB1Catenin beta-1. (781 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (784 aa)
PTGER3Prostaglandin E2 receptor EP3 subtype. (387 aa)
IL10RBInterleukin-10 receptor subunit beta. (375 aa)
LOC110569839Neuroendocrine secretory protein 55. (246 aa)
GNASGuanine nucleotide-binding protein G(S) subunit alpha isoforms XLas isoform X1. (1003 aa)
Your Current Organism:
Neomonachus schauinslandi
NCBI taxonomy Id: 29088
Other names: Hawaiian monk seal, Monachus schauinslandi, N. schauinslandi
Server load: low (38%) [HD]