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| | PLCG2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1200 aa) |
| | MAP2K7 | Dual specificity mitogen-activated protein kinase kinase 7 isoform X1. (440 aa) |
| | GNG14 | LOW QUALITY PROTEIN: uncharacterized LOC105372280 homolog. (100 aa) |
| | GNG7 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa) |
| | TICAM1 | TIR domain-containing adapter molecule 1; Involved in innate immunity against invading pathogens. Component of a multi-helicase-TICAM1 complex that acts as a cytoplasmic sensor of viral double-stranded RNA (dsRNA) and plays a role in the activation of a cascade of antiviral responses including the induction of proinflammatory cytokines. (767 aa) |
| | CCR8 | C-C chemokine receptor type 8; Belongs to the G-protein coupled receptor 1 family. (355 aa) |
| | NFATC3 | Nuclear factor of activated T-cells, cytoplasmic 3 isoform X1. (1075 aa) |
| | GABARAPL2 | Gamma-aminobutyric acid receptor-associated protein-like 2. (117 aa) |
| | C3 | Complement C3. (1661 aa) |
| | ICAM1 | Intercellular adhesion molecule 1. (533 aa) |
| | MAP2K2 | Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa) |
| | TYK2 | Tyrosine-protein kinase. (1189 aa) |
| | CASP8 | LOW QUALITY PROTEIN: caspase-8; Belongs to the peptidase C14A family. (486 aa) |
| | GNGT2 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (118 aa) |
| | TRADD | Tumor necrosis factor receptor type 1-associated DEATH domain protein isoform X1. (312 aa) |
| | CXCL8 | Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (104 aa) |
| | HIF1A | Hypoxia-inducible factor 1-alpha. (823 aa) |
| | TCF7 | Transcription factor 7. (419 aa) |
| | IL6ST | Interleukin-6 receptor subunit beta isoform X1. (914 aa) |
| | LOC110592210 | Calmodulin-like; Belongs to the calmodulin family. (149 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) |
| | CREB1 | Cyclic AMP-responsive element-binding protein 1. (327 aa) |
| | STAT1 | Signal transducer and activator of transcription. (750 aa) |
| | LOC110592156 | Calmodulin-like; Belongs to the calmodulin family. (98 aa) |
| | LOC110592054 | Cytochrome c, testis-specific; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | ZFP36 | mRNA decay activator protein ZFP36. (325 aa) |
| | LOC110591463 | C-X-C motif chemokine. (107 aa) |
| | LOC110591473 | C-X-C motif chemokine. (107 aa) |
| | LOC110591392 | Mitogen-activated protein kinase. (300 aa) |
| | LOC110591461 | C-X-C motif chemokine. (105 aa) |
| | LOC110591391 | Mitogen-activated protein kinase 10-like. (176 aa) |
| | PIK3R1 | Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (725 aa) |
| | CSF2 | Granulocyte-macrophage colony-stimulating factor. (153 aa) |
| | PPP3CB | Serine/threonine-protein phosphatase. (527 aa) |
| | GNG2 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (71 aa) |
| | PPP3R1 | Calcineurin subunit B type 1. (170 aa) |
| | ATG14 | Beclin 1-associated autophagy-related key regulator. (492 aa) |
| | RPS27A | ubiquitin-40S ribosomal protein S27a. (156 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa) |
| | MAPK8 | Mitogen-activated protein kinase. (427 aa) |
| | TCF7L2 | Transcription factor 7-like 2. (446 aa) |
| | CHUK | Inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1. (744 aa) |
| | TCF7L1 | Transcription factor 7-like 1. (463 aa) |
| | IFNA5 | LOW QUALITY PROTEIN: interferon alpha-5. (187 aa) |
| | LOC110588689 | ubiquitin-40S ribosomal protein S27a-like. (154 aa) |
| | LOC110587131 | Interferon alpha-16-like. (182 aa) |
| | PPP3CC | Serine/threonine-protein phosphatase. (525 aa) |
| | E2F3 | Transcription factor E2F3 isoform X1. (466 aa) |
| | LOC110588252 | Ubiquitin. (77 aa) |
| | CREBBP | CREB-binding protein isoform X3. (2433 aa) |
| | GNG13 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13. (67 aa) |
| | IRF9 | Interferon regulatory factor 9. (410 aa) |
| | NFKBIA | NF-kappa-B inhibitor alpha. (314 aa) |
| | EIF2AK2 | Interferon-induced, double-stranded RNA-activated protein kinase. (541 aa) |
| | IFNB1 | Interferon beta. (182 aa) |
| | LOC110586919 | LOW QUALITY PROTEIN: HLA class I histocompatibility antigen, A-3 alpha chain; Belongs to the MHC class I family. (437 aa) |
| | PIK3R6 | Phosphoinositide 3-kinase regulatory subunit 6. (755 aa) |
| | PIK3R5 | Phosphoinositide 3-kinase regulatory subunit 5 isoform X1. (1008 aa) |
| | LOC110586587 | Calmodulin-like protein 3; Belongs to the calmodulin family. (149 aa) |
| | MAP2K4 | Dual specificity mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (400 aa) |
| | CALML5 | Calmodulin-like protein 5. (149 aa) |
| | LOC110586377 | ubiquitin-60S ribosomal protein L40-like. (162 aa) |
| | SYK | Tyrosine-protein kinase. (635 aa) |
| | TLR3 | Toll-like receptor 3; Belongs to the Toll-like receptor family. (905 aa) |
| | FAS | Tumor necrosis factor receptor superfamily member 6. (314 aa) |
| | GNG4 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa) |
| | CALML4 | LOW QUALITY PROTEIN: calmodulin-like protein 4. (197 aa) |
| | IFNGR1 | LOW QUALITY PROTEIN: interferon gamma receptor 1. (474 aa) |
| | NFATC4 | Nuclear factor of activated T-cells, cytoplasmic 4. (902 aa) |
| | RAF1 | RAF proto-oncogene serine/threonine-protein kinase. (648 aa) |
| | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1 isoform X1. (2709 aa) |
| | UBB | LOW QUALITY PROTEIN: polyubiquitin-B. (156 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (381 aa) |
| | JAK2 | Tyrosine-protein kinase. (1130 aa) |
| | ANGPT2 | Angiopoietin-2. (541 aa) |
| | IRF7 | Interferon regulatory factor 7. (496 aa) |
| | CASP3 | Caspase-3 isoform X1; Belongs to the peptidase C14A family. (302 aa) |
| | GNB5 | Guanine nucleotide-binding protein subunit beta-5. (395 aa) |
| | MAP2K1 | Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa) |
| | VEGFA | Vascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (549 aa) |
| | GABARAPL1 | Gamma-aminobutyric acid receptor-associated protein-like 1. (133 aa) |
| | LOC110580994 | Early activation antigen CD69-like. (199 aa) |
| | LOC110580777 | C-type lectin domain family 2 member B-like. (142 aa) |
| | GSK3B | Glycogen synthase kinase-3 beta isoform X1; Belongs to the protein kinase superfamily. (433 aa) |
| | ATG3 | Autophagy-related protein 3. (314 aa) |
| | CLEC2D | C-type lectin domain family 2 member D. (200 aa) |
| | CD86 | T-lymphocyte activation antigen CD86. (332 aa) |
| | GNB4 | Guanine nucleotide-binding protein subunit beta-4. (340 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
| | HRAS | GTPase HRas isoform X1. (189 aa) |
| | GNG5 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa) |
| | GNGT1 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa) |
| | NRAS | GTPase NRas. (189 aa) |
| | E2F1 | LOW QUALITY PROTEIN: transcription factor E2F1. (483 aa) |
| | LOC110581611 | DLA class I histocompatibility antigen, A9/A9 alpha chain-like isoform X1. (188 aa) |
| | GNG11 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa) |
| | PPP3R2 | Calcineurin subunit B type 2. (170 aa) |
| | LOC110579961 | Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | GNG10 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa) |
| | TRAF2 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (523 aa) |
| | GNB3 | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3. (340 aa) |
| | PREX2 | Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein. (1602 aa) |
| | ITPR2 | Inositol 1,4,5-trisphosphate receptor type 2. (2701 aa) |
| | TNFRSF1A | Tumor necrosis factor receptor superfamily member 1A. (451 aa) |
| | KRAS | GTPase KRas. (188 aa) |
| | BID | BH3-interacting domain death agonist; Counters the protective effect of Bcl-2. (240 aa) |
| | CSDE1 | Cold shock domain-containing protein E1 isoform X1. (798 aa) |
| | MAPK9 | Mitogen-activated protein kinase. (424 aa) |
| | LOC110580263 | H-2 class I histocompatibility antigen, Q10 alpha chain-like isoform X1; Belongs to the MHC class I family. (387 aa) |
| | PDGFB | Platelet-derived growth factor subunit B isoform X1; Belongs to the PDGF/VEGF growth factor family. (241 aa) |
| | CUNH7orf31 | Uncharacterized protein C7orf31 homolog. (590 aa) |
| | IL6 | Interleukin-6 isoform X1. (212 aa) |
| | CDK6 | Cyclin-dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa) |
| | RB1 | Retinoblastoma-associated protein. (934 aa) |
| | MAPK1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (361 aa) |
| | MAPK11 | Mitogen-activated protein kinase. (364 aa) |
| | SRC | Tyrosine-protein kinase. (536 aa) |
| | PLCG1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1289 aa) |
| | EP300 | Histone acetyltransferase p300. (2420 aa) |
| | LYN | Tyrosine-protein kinase. (512 aa) |
| | MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (438 aa) |
| | PREX1 | Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein. (1573 aa) |
| | MAPK12 | Mitogen-activated protein kinase. (367 aa) |
| | CCND1 | G1/S-specific cyclin-D1; Belongs to the cyclin family. (295 aa) |
| | NFATC1 | Nuclear factor of activated T-cells, cytoplasmic 1 isoform X1. (891 aa) |
| | STAT2 | Signal transducer and activator of transcription. (854 aa) |
| | CDK4 | Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa) |
| | GNG3 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa) |
| | IKBKE | Inhibitor of nuclear factor kappa-B kinase subunit epsilon isoform X1. (774 aa) |
| | PIK3C3 | Phosphatidylinositol 3-kinase catalytic subunit type 3. (887 aa) |
| | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa) |
| | LEF1 | Lymphoid enhancer-binding factor 1 isoform X1. (399 aa) |
| | NFATC2 | Nuclear factor of activated T-cells, cytoplasmic 2. (920 aa) |
| | PIK3R3 | Phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1. (507 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR. (2557 aa) |
| | CASP9 | Caspase-9; Belongs to the peptidase C14A family. (447 aa) |
| | GNB1 | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1. (340 aa) |
| | UBA52 | ubiquitin-60S ribosomal protein L40. (128 aa) |
| | FADD | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (218 aa) |
| | RELA | Transcription factor p65. (531 aa) |
| | LOC110575688 | HLA class I histocompatibility antigen, A-24 alpha chain-like; Belongs to the MHC class I family. (255 aa) |
| | ITPR3 | Inositol 1,4,5-trisphosphate receptor type 3. (2584 aa) |
| | CDKN1A | Cyclin-dependent kinase inhibitor 1. (161 aa) |
| | MAPK14 | Mitogen-activated protein kinase. (360 aa) |
| | MAPK13 | Mitogen-activated protein kinase. (365 aa) |
| | BAK1 | Bcl-2 homologous antagonist/killer. (211 aa) |
| | MAPKAPK2 | MAP kinase-activated protein kinase 2 isoform X1; Belongs to the protein kinase superfamily. (402 aa) |
| | PTGS2 | Prostaglandin G/H synthase 2. (604 aa) |
| | CALML6 | Calmodulin-like protein 6. (232 aa) |
| | JUN | Transcription factor AP-1 isoform X1; Belongs to the bZIP family. (335 aa) |
| | E2F2 | Transcription factor E2F2. (449 aa) |
| | STAT3 | Signal transducer and activator of transcription. (770 aa) |
| | PIK3R2 | Phosphatidylinositol 3-kinase regulatory subunit beta isoform X1. (726 aa) |
| | CCR3 | C-C chemokine receptor type 3; Belongs to the G-protein coupled receptor 1 family. (359 aa) |
| | LOC110574374 | C-C chemokine receptor type 1-like; Belongs to the G-protein coupled receptor 1 family. (355 aa) |
| | LOC110574370 | C-C chemokine receptor type 5; Belongs to the G-protein coupled receptor 1 family. (352 aa) |
| | PIK3CG | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform; Belongs to the PI3/PI4-kinase family. (1102 aa) |
| | BECN2 | Beclin-2. (432 aa) |
| | IKBKG | NF-kappa-B essential modulator. (419 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | FGF2 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (374 aa) |
| | IRF3 | Interferon regulatory factor 3 isoform X1. (458 aa) |
| | BECN1 | Beclin-1 isoform X1. (448 aa) |
| | IKBKB | Inhibitor of nuclear factor kappa-B kinase subunit beta. (756 aa) |
| | NFKB1 | Nuclear factor NF-kappa-B p105 subunit isoform X4. (987 aa) |
| | GNG12 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa) |
| | JAK1 | Tyrosine-protein kinase. (1156 aa) |
| | BAX | Apoptosis regulator BAX isoform X1. (192 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) |
| | GNG8 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa) |
| | CCR4 | C-C chemokine receptor type 4; Belongs to the G-protein coupled receptor 1 family. (360 aa) |
| | IFNAR1 | Interferon alpha/beta receptor 1. (560 aa) |
| | RCAN1 | Calcipressin-1 isoform X1. (249 aa) |
| | CTNNB1 | Catenin beta-1. (781 aa) |
| | MAP2K6 | Dual specificity mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa) |
| | TBK1 | Serine/threonine-protein kinase TBK1 isoform X1. (729 aa) |
| | ERAS | GTPase ERas. (233 aa) |
| | IFNAR2 | Interferon alpha/beta receptor 2 isoform X1. (516 aa) |
| | FOS | Proto-oncogene c-Fos. (380 aa) |
| | PIK3CB | LOW QUALITY PROTEIN: phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform; Belongs to the PI3/PI4-kinase family. (1070 aa) |
| | CALM1 | Calmodulin-1; Belongs to the calmodulin family. (149 aa) |
| | TRAF3 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (568 aa) |
| | GNB2 | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2. (340 aa) |
| | PPP3CA | Serine/threonine-protein phosphatase. (526 aa) |
| | LOC110572425 | Parvalbumin beta-like. (129 aa) |
