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| | EZR | Ezrin isoform X1. (586 aa) |
| | KIF23 | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (940 aa) |
| | VEGFA | Vascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (549 aa) |
| | CEP152 | Centrosomal protein of 152 kDa isoform X1. (1723 aa) |
| | SHC4 | SHC-transforming protein 4. (630 aa) |
| | MAP2K1 | Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa) |
| | CASP3 | Caspase-3 isoform X1; Belongs to the peptidase C14A family. (302 aa) |
| | CDKN1A | Cyclin-dependent kinase inhibitor 1. (161 aa) |
| | STMN1 | Stathmin; Belongs to the stathmin family. (149 aa) |
| | GLS | Glutaminase kidney isoform, mitochondrial isoform X1. (672 aa) |
| | ERBB2 | Receptor protein-tyrosine kinase. (1260 aa) |
| | IGF2BP1 | Insulin-like growth factor 2 mRNA-binding protein 1 isoform X1. (577 aa) |
| | EGFR | Receptor protein-tyrosine kinase. (1207 aa) |
| | PDGFRA | Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1089 aa) |
| | HOXD10 | Homeobox protein Hox-D10. (410 aa) |
| | PAK4 | Non-specific serine/threonine protein kinase. (594 aa) |
| | APC | Adenomatous polyposis coli protein. (2844 aa) |
| | BMPR2 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (944 aa) |
| | PIK3R1 | Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (725 aa) |
| | CDC25C | M-phase inducer phosphatase 3. (529 aa) |
| | SIRT1 | NAD-dependent protein deacetylase sirtuin-1. (746 aa) |
| | PDCD4 | Programmed cell death protein 4 isoform X1. (469 aa) |
| | EFNA5 | ephrin-A5 isoform X1; Belongs to the ephrin family. (228 aa) |
| | SOS2 | Son of sevenless homolog 2 isoform X1. (1338 aa) |
| | CCNE1 | G1/S-specific cyclin-E1 isoform X1; Belongs to the cyclin family. (410 aa) |
| | PRKCE | Protein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (736 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa) |
| | TGFB2 | Transforming growth factor beta; Belongs to the TGF-beta family. (414 aa) |
| | SOX11 | Transcription factor SOX. (441 aa) |
| | UBE2I | SUMO-conjugating enzyme UBC9; Belongs to the ubiquitin-conjugating enzyme family. (158 aa) |
| | DDIT4 | DNA damage-inducible transcript 4 protein. (231 aa) |
| | CCNG1 | cyclin-G1; Belongs to the cyclin family. (295 aa) |
| | PLAU | Urokinase-type plasminogen activator. (432 aa) |
| | MET | Hepatocyte growth factor receptor. (1382 aa) |
| | SOX4 | Transcription factor SOX. (474 aa) |
| | LOC110587203 | Cytochrome P450 1B1; Belongs to the cytochrome P450 family. (543 aa) |
| | SOS1 | Son of sevenless homolog 1. (1333 aa) |
| | TNXB | tenascin-X. (2215 aa) |
| | VIM | Vimentin; Belongs to the intermediate filament family. (466 aa) |
| | FZD3 | Frizzled-3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa) |
| | GPSM3 | G-protein-signaling modulator 3. (162 aa) |
| | NOTCH4 | Neurogenic locus notch homolog protein 4. (1996 aa) |
| | E2F3 | Transcription factor E2F3 isoform X1. (466 aa) |
| | BMI1 | Polycomb complex protein BMI-1 isoform X1. (326 aa) |
| | ST14 | Suppressor of tumorigenicity 14 protein homolog; Degrades extracellular matrix. Belongs to the peptidase S1 family. (855 aa) |
| | CREBBP | CREB-binding protein isoform X3. (2433 aa) |
| | SOCS1 | Suppressor of cytokine signaling 1. (216 aa) |
| | ATM | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3054 aa) |
| | PTEN | Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa) |
| | ZEB2 | Zinc finger E-box-binding homeobox 2 isoform X1. (1214 aa) |
| | ABCC1 | Multidrug resistance-associated protein 1. (1633 aa) |
| | SPRY2 | Protein sprouty homolog 2. (315 aa) |
| | LOC110585403 | Bcl-2-like protein 2. (193 aa) |
| | DNMT3A | DNA (Cytosine-5)-methyltransferase 3A; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (909 aa) |
| | BMF | Bcl-2-modifying factor isoform X1. (184 aa) |
| | BCL2L11 | Bcl-2-like protein 11 isoform X1. (131 aa) |
| | PDGFRB | Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1098 aa) |
| | RDX | Radixin. (583 aa) |
| | HDAC2 | Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (488 aa) |
| | IRS2 | Insulin receptor substrate 2. (1330 aa) |
| | THBS1 | Thrombospondin-1. (1170 aa) |
| | MARCKS | Myristoylated alanine-rich C-kinase substrate. (333 aa) |
| | EZH2 | Histone-lysine N-methyltransferase EZH2 isoform X2. (751 aa) |
| | FOXP1 | Forkhead box protein P1 isoform X1. (577 aa) |
| | RAF1 | RAF proto-oncogene serine/threonine-protein kinase. (648 aa) |
| | TP63 | Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (587 aa) |
| | MAPK7 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (814 aa) |
| | LOC110584545 | Histone deacetylase 5-like. (117 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (381 aa) |
| | PDGFA | Platelet-derived growth factor subunit A isoform X1; Belongs to the PDGF/VEGF growth factor family. (331 aa) |
| | MAP2K2 | Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa) |
| | APC2 | Adenomatous polyposis coli protein 2 isoform X1. (2265 aa) |
| | DNMT1 | DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (1613 aa) |
| | CRK | Adapter molecule crk isoform X1. (304 aa) |
| | NFKB1 | Nuclear factor NF-kappa-B p105 subunit isoform X4. (987 aa) |
| | FSCN1 | Fascin. (493 aa) |
| | HNRNPK | Heterogeneous nuclear ribonucleoprotein K isoform X1. (464 aa) |
| | LOC110569858 | 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial isoform X1; Belongs to the cytochrome P450 family. (514 aa) |
| | LOC110570219 | Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2-like. (470 aa) |
| | TRIM71 | E3 ubiquitin-protein ligase TRIM71. (869 aa) |
| | ITGB3 | Integrin beta; Belongs to the integrin beta chain family. (784 aa) |
| | FGFR3 | Fibroblast growth factor receptor. (806 aa) |
| | ERAS | GTPase ERas. (233 aa) |
| | SLC7A1 | High affinity cationic amino acid transporter 1. (629 aa) |
| | HDAC4 | Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1028 aa) |
| | PRKCA | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa) |
| | WNT3 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (400 aa) |
| | HMGA2 | High mobility group protein HMGI-C. (124 aa) |
| | MDM2 | E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (487 aa) |
| | RPS6KA5 | Ribosomal protein S6 kinase. (798 aa) |
| | PIK3CB | LOW QUALITY PROTEIN: phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform; Belongs to the PI3/PI4-kinase family. (1070 aa) |
| | DICER1 | Endoribonuclease Dicer isoform X1; Belongs to the helicase family. Dicer subfamily. (1923 aa) |
| | IKBKB | Inhibitor of nuclear factor kappa-B kinase subunit beta. (756 aa) |
| | BRCA1 | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] (1877 aa) |
| | RPTOR | Regulatory-associated protein of mTOR. (1335 aa) |
| | EFNA1 | ephrin-A1; Belongs to the ephrin family. (205 aa) |
| | GRB2 | Growth factor receptor-bound protein 2. (217 aa) |
| | EFNA3 | ephrin-A3 isoform X1; Belongs to the ephrin family. (232 aa) |
| | TNN | LOW QUALITY PROTEIN: tenascin-N. (1241 aa) |
| | IRS1 | Insulin receptor substrate 1. (1236 aa) |
| | NOTCH3 | Neurogenic locus notch homolog protein 3 isoform X1. (2322 aa) |
| | ADAM15 | Disintegrin and metalloproteinase domain-containing protein 15 isoform X1. (893 aa) |
| | PIK3R2 | Phosphatidylinositol 3-kinase regulatory subunit beta isoform X1. (726 aa) |
| | SHC1 | SHC-transforming protein 1 isoform X1. (584 aa) |
| | HDAC5 | Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1134 aa) |
| | FSCN2 | Fascin-2 isoform X1. (513 aa) |
| | STAT3 | Signal transducer and activator of transcription. (770 aa) |
| | E2F2 | Transcription factor E2F2. (449 aa) |
| | TNR | tenascin-R isoform X1. (1358 aa) |
| | EFNA4 | ephrin-A4; Belongs to the ephrin family. (204 aa) |
| | PRKCG | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa) |
| | PTGS2 | Prostaglandin G/H synthase 2. (604 aa) |
| | BAK1 | Bcl-2 homologous antagonist/killer. (211 aa) |
| | PIM1 | Serine/threonine-protein kinase; Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily. (320 aa) |
| | PLCG2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1200 aa) |
| | EFNA2 | ephrin-A2. (164 aa) |
| | CSDE1 | Cold shock domain-containing protein E1 isoform X1. (798 aa) |
| | PDGFB | Platelet-derived growth factor subunit B isoform X1; Belongs to the PDGF/VEGF growth factor family. (241 aa) |
| | CDK6 | Cyclin-dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa) |
| | MAPK1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (361 aa) |
| | MMP9 | Matrix metalloproteinase-9 isoform X1. (704 aa) |
| | HMOX1 | Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. (288 aa) |
| | SOX12 | Transcription factor SOX. (314 aa) |
| | CDC25B | LOW QUALITY PROTEIN: M-phase inducer phosphatase 2. (574 aa) |
| | PLCG1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1289 aa) |
| | EP300 | Histone acetyltransferase p300. (2420 aa) |
| | PRKCB | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (634 aa) |
| | ITGA5 | Integrin alpha-5; Belongs to the integrin alpha chain family. (1054 aa) |
| | GLS2 | Glutaminase liver isoform, mitochondrial isoform X1. (602 aa) |
| | CCNE2 | G1/S-specific cyclin-E2; Belongs to the cyclin family. (404 aa) |
| | ERBB3 | Receptor tyrosine-protein kinase erbB-3. (1339 aa) |
| | RASSF1 | Ras association domain-containing protein 1 isoform X1. (340 aa) |
| | MMP16 | Matrix metalloproteinase-16. (607 aa) |
| | MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (438 aa) |
| | ZFPM2 | Zinc finger protein ZFPM2. (1148 aa) |
| | SERPINB5 | Serpin B5; Belongs to the serpin family. (375 aa) |
| | MCL1 | LOW QUALITY PROTEIN: induced myeloid leukemia cell differentiation protein Mcl-1. (347 aa) |
| | CRKL | Crk-like protein. (303 aa) |
| | CCND1 | G1/S-specific cyclin-D1; Belongs to the cyclin family. (295 aa) |
| | TIMP3 | Metalloproteinase inhibitor 3. (211 aa) |
| | CDKN1C | Cyclin-dependent kinase inhibitor 1C. (263 aa) |
| | CDC25A | M-phase inducer phosphatase 1. (522 aa) |
| | SLC45A3 | Solute carrier family 45 member 3. (552 aa) |
| | ZEB1 | Zinc finger E-box-binding homeobox 1. (905 aa) |
| | MDM4 | Protein Mdm4; Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Belongs to the MDM2/MDM4 family. (492 aa) |
| | BCL2 | Apoptosis regulator Bcl-2 isoform X1. (234 aa) |
| | ROCK1 | Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1354 aa) |
| | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa) |
| | PIK3R3 | Phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1. (507 aa) |
| | HDAC1 | Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (482 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR. (2557 aa) |
| | CD44 | CD44 antigen isoform X1. (785 aa) |
| | CDCA5 | Sororin. (253 aa) |
| | NOTCH2 | Neurogenic locus notch homolog protein 2. (2471 aa) |
| | CCND2 | G1/S-specific cyclin-D2; Belongs to the cyclin family. (289 aa) |
| | KRAS | GTPase KRas. (188 aa) |
| | DNMT3B | DNA (Cytosine-5)-methyltransferase 3B isoform X1; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (856 aa) |
| | ABL1 | Tyrosine-protein kinase. (1137 aa) |
| | RECK | LOW QUALITY PROTEIN: reversion-inducing cysteine-rich protein with Kazal motifs. (971 aa) |
| | IGF2BP3 | Insulin-like growth factor 2 mRNA-binding protein 3 isoform X2. (580 aa) |
| | E2F1 | LOW QUALITY PROTEIN: transcription factor E2F1. (483 aa) |
| | NRAS | GTPase NRas. (189 aa) |
| | HRAS | GTPase HRas isoform X1. (189 aa) |
| | EYS | LOW QUALITY PROTEIN: protein eyes shut homolog. (595 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
| | CDKN1B | Cyclin-dependent kinase inhibitor 1B. (198 aa) |
| | NOTCH1 | Neurogenic locus notch homolog protein 1 isoform X1. (2567 aa) |
| | TNC | Tenascin. (2201 aa) |
