STRINGSTRING
CRK CRK RAP1B RAP1B ERAS ERAS GAB1 GAB1 TGFB3 TGFB3 PIK3CB PIK3CB ARAF ARAF AKT1 AKT1 GRB2 GRB2 ARNT2 ARNT2 FH FH AKT3 AKT3 PRCC PRCC PIK3R2 PIK3R2 JUN JUN SLC2A1 SLC2A1 LOC110575329 LOC110575329 CDKN1A CDKN1A PIK3R3 PIK3R3 PIK3CD PIK3CD CDC42 CDC42 PPP1R14B PPP1R14B PAK3 PAK3 BAD BAD CRKL CRKL CUL2 CUL2 ARNT ARNT EP300 EP300 MAPK1 MAPK1 RBX1 RBX1 PDGFB PDGFB CSDE1 CSDE1 RAP1A RAP1A ELOC ELOC KRAS KRAS PAK5 PAK5 HGF HGF NRAS NRAS HRAS HRAS PIK3CA PIK3CA BRAF BRAF RAPGEF1 RAPGEF1 VEGFA VEGFA MAP2K1 MAP2K1 PAK2 PAK2 VHL VHL LOC110582911 LOC110582911 RAF1 RAF1 PAK6 PAK6 EGLN3 EGLN3 ETS1 ETS1 FLCN FLCN EGLN1 EGLN1 ELOB ELOB CREBBP CREBBP PTPN11 PTPN11 SOS1 SOS1 TGFA TGFA MET MET TGFB2 TGFB2 MAPK3 MAPK3 TGFB1 TGFB1 EGLN2 EGLN2 SOS2 SOS2 EPAS1 EPAS1 PIK3R1 PIK3R1 PAK4 PAK4 AKT2 AKT2 HIF1A HIF1A PAK1 PAK1 MAP2K2 MAP2K2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CRKAdapter molecule crk isoform X1. (304 aa)
RAP1BRas-related protein Rap-1b. (184 aa)
ERASGTPase ERas. (233 aa)
GAB1GRB2-associated-binding protein 1 isoform X1. (724 aa)
TGFB3Transforming growth factor beta-3. (461 aa)
PIK3CBLOW QUALITY PROTEIN: phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform; Belongs to the PI3/PI4-kinase family. (1070 aa)
ARAFSerine/threonine-protein kinase A-Raf. (606 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
GRB2Growth factor receptor-bound protein 2. (217 aa)
ARNT2Aryl hydrocarbon receptor nuclear translocator 2 isoform X1. (712 aa)
FHFumarate hydratase, mitochondrial isoform X1. (508 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
PRCCProline-rich protein PRCC. (491 aa)
PIK3R2Phosphatidylinositol 3-kinase regulatory subunit beta isoform X1. (726 aa)
JUNTranscription factor AP-1 isoform X1; Belongs to the bZIP family. (335 aa)
SLC2A1Solute carrier family 2, facilitated glucose transporter member 1 isoform X1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (501 aa)
LOC110575329Tyrosine-protein phosphatase non-receptor type 11-like. (582 aa)
CDKN1ACyclin-dependent kinase inhibitor 1. (161 aa)
PIK3R3Phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1. (507 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa)
CDC42Cell division control protein 42 homolog. (191 aa)
PPP1R14BLOW QUALITY PROTEIN: protein phosphatase 1 regulatory subunit 14B-like. (203 aa)
PAK3Non-specific serine/threonine protein kinase. (544 aa)
BADBcl2-associated agonist of cell death isoform X1. (205 aa)
CRKLCrk-like protein. (303 aa)
CUL2Cullin-2 isoform X1; Belongs to the cullin family. (745 aa)
ARNTAryl hydrocarbon receptor nuclear translocator isoform X1. (786 aa)
EP300Histone acetyltransferase p300. (2420 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (361 aa)
RBX1E3 ubiquitin-protein ligase RBX1. (108 aa)
PDGFBPlatelet-derived growth factor subunit B isoform X1; Belongs to the PDGF/VEGF growth factor family. (241 aa)
CSDE1Cold shock domain-containing protein E1 isoform X1. (798 aa)
RAP1ARas-related protein Rap-1A. (184 aa)
ELOCelongin-C isoform X1; Belongs to the SKP1 family. (148 aa)
KRASGTPase KRas. (188 aa)
PAK5Non-specific serine/threonine protein kinase. (719 aa)
HGFHepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (730 aa)
NRASGTPase NRas. (189 aa)
HRASGTPase HRas isoform X1. (189 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
BRAFSerine/threonine-protein kinase B-raf. (764 aa)
RAPGEF1Rap guanine nucleotide exchange factor 1. (1025 aa)
VEGFAVascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (549 aa)
MAP2K1Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
PAK2Non-specific serine/threonine protein kinase. (524 aa)
VHLVon Hippel-Lindau disease tumor suppressor. (219 aa)
LOC110582911Transcription factor E3. (229 aa)
RAF1RAF proto-oncogene serine/threonine-protein kinase. (648 aa)
PAK6Non-specific serine/threonine protein kinase. (681 aa)
EGLN3Egl nine homolog 3. (239 aa)
ETS1Protein C-ets-1. (441 aa)
FLCNFolliculin isoform X1. (647 aa)
EGLN1Egl nine homolog 1. (425 aa)
ELOBelongin-B. (118 aa)
CREBBPCREB-binding protein isoform X3. (2433 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (617 aa)
SOS1Son of sevenless homolog 1. (1333 aa)
TGFAProtransforming growth factor alpha. (160 aa)
METHepatocyte growth factor receptor. (1382 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (414 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
EGLN2Egl nine homolog 2 isoform X1. (474 aa)
SOS2Son of sevenless homolog 2 isoform X1. (1338 aa)
EPAS1Endothelial PAS domain-containing protein 1. (865 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (725 aa)
PAK4Non-specific serine/threonine protein kinase. (594 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
HIF1AHypoxia-inducible factor 1-alpha. (823 aa)
PAK1Non-specific serine/threonine protein kinase. (544 aa)
MAP2K2Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa)
Your Current Organism:
Neomonachus schauinslandi
NCBI taxonomy Id: 29088
Other names: Hawaiian monk seal, Monachus schauinslandi, N. schauinslandi
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