Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| birA | folA | BPEN_190 | BPEN_128 | biotin-[acetylCoA carboxylase] holoenzyme synthetase; Bifunctional; ortholog to Escherichia coli bnum: b3973; MultiFun: Information transfer 2.2.2; Metabolism 1.5.3.1; Regulation 3.1.2.3, 3.3.1; transcriptional repressor of biotin synthesis (BirA family). | Dihydrofolate reductase type I; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | 0.640 |
| birA | folB | BPEN_190 | BPEN_062 | biotin-[acetylCoA carboxylase] holoenzyme synthetase; Bifunctional; ortholog to Escherichia coli bnum: b3973; MultiFun: Information transfer 2.2.2; Metabolism 1.5.3.1; Regulation 3.1.2.3, 3.3.1; transcriptional repressor of biotin synthesis (BirA family). | Dihydroneopterin aldolase, also has dihydroneopterin triphosphate; Ortholog to Escherichia coli bnum: b3058; MultiFun: Metabolism 1.5.3.2. | 0.589 |
| birA | folC | BPEN_190 | BPEN_510 | biotin-[acetylCoA carboxylase] holoenzyme synthetase; Bifunctional; ortholog to Escherichia coli bnum: b3973; MultiFun: Information transfer 2.2.2; Metabolism 1.5.3.1; Regulation 3.1.2.3, 3.3.1; transcriptional repressor of biotin synthesis (BirA family). | Folylpolyglutamate synthase; Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10- formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives. | 0.476 |
| birA | folE | BPEN_190 | BPEN_487 | biotin-[acetylCoA carboxylase] holoenzyme synthetase; Bifunctional; ortholog to Escherichia coli bnum: b3973; MultiFun: Information transfer 2.2.2; Metabolism 1.5.3.1; Regulation 3.1.2.3, 3.3.1; transcriptional repressor of biotin synthesis (BirA family). | GTP cyclohydrolase I; Ortholog to Escherichia coli bnum: b2153; MultiFun: Metabolism 1.5.3.2. | 0.519 |
| birA | folK | BPEN_190 | BPEN_155 | biotin-[acetylCoA carboxylase] holoenzyme synthetase; Bifunctional; ortholog to Escherichia coli bnum: b3973; MultiFun: Information transfer 2.2.2; Metabolism 1.5.3.1; Regulation 3.1.2.3, 3.3.1; transcriptional repressor of biotin synthesis (BirA family). | 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase; Ortholog to Escherichia coli bnum: b0142; MultiFun: Metabolism 1.5.3.2. | 0.549 |
| birA | folP | BPEN_190 | BPEN_102 | biotin-[acetylCoA carboxylase] holoenzyme synthetase; Bifunctional; ortholog to Escherichia coli bnum: b3973; MultiFun: Information transfer 2.2.2; Metabolism 1.5.3.1; Regulation 3.1.2.3, 3.3.1; transcriptional repressor of biotin synthesis (BirA family). | 7,8-dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.553 |
| birA | ribA | BPEN_190 | BPEN_437 | biotin-[acetylCoA carboxylase] holoenzyme synthetase; Bifunctional; ortholog to Escherichia coli bnum: b3973; MultiFun: Information transfer 2.2.2; Metabolism 1.5.3.1; Regulation 3.1.2.3, 3.3.1; transcriptional repressor of biotin synthesis (BirA family). | GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate. | 0.455 |
| birA | ribD | BPEN_190 | BPEN_240 | biotin-[acetylCoA carboxylase] holoenzyme synthetase; Bifunctional; ortholog to Escherichia coli bnum: b3973; MultiFun: Information transfer 2.2.2; Metabolism 1.5.3.1; Regulation 3.1.2.3, 3.3.1; transcriptional repressor of biotin synthesis (BirA family). | Pyrimidine deaminase/reductase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.648 |
| folA | birA | BPEN_128 | BPEN_190 | Dihydrofolate reductase type I; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | biotin-[acetylCoA carboxylase] holoenzyme synthetase; Bifunctional; ortholog to Escherichia coli bnum: b3973; MultiFun: Information transfer 2.2.2; Metabolism 1.5.3.1; Regulation 3.1.2.3, 3.3.1; transcriptional repressor of biotin synthesis (BirA family). | 0.640 |
| folA | folB | BPEN_128 | BPEN_062 | Dihydrofolate reductase type I; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | Dihydroneopterin aldolase, also has dihydroneopterin triphosphate; Ortholog to Escherichia coli bnum: b3058; MultiFun: Metabolism 1.5.3.2. | 0.654 |
| folA | folC | BPEN_128 | BPEN_510 | Dihydrofolate reductase type I; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | Folylpolyglutamate synthase; Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10- formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives. | 0.960 |
| folA | folE | BPEN_128 | BPEN_487 | Dihydrofolate reductase type I; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | GTP cyclohydrolase I; Ortholog to Escherichia coli bnum: b2153; MultiFun: Metabolism 1.5.3.2. | 0.681 |
| folA | folK | BPEN_128 | BPEN_155 | Dihydrofolate reductase type I; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase; Ortholog to Escherichia coli bnum: b0142; MultiFun: Metabolism 1.5.3.2. | 0.650 |
| folA | folP | BPEN_128 | BPEN_102 | Dihydrofolate reductase type I; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | 7,8-dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.706 |
| folA | ribD | BPEN_128 | BPEN_240 | Dihydrofolate reductase type I; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | Pyrimidine deaminase/reductase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.541 |
| folB | birA | BPEN_062 | BPEN_190 | Dihydroneopterin aldolase, also has dihydroneopterin triphosphate; Ortholog to Escherichia coli bnum: b3058; MultiFun: Metabolism 1.5.3.2. | biotin-[acetylCoA carboxylase] holoenzyme synthetase; Bifunctional; ortholog to Escherichia coli bnum: b3973; MultiFun: Information transfer 2.2.2; Metabolism 1.5.3.1; Regulation 3.1.2.3, 3.3.1; transcriptional repressor of biotin synthesis (BirA family). | 0.589 |
| folB | folA | BPEN_062 | BPEN_128 | Dihydroneopterin aldolase, also has dihydroneopterin triphosphate; Ortholog to Escherichia coli bnum: b3058; MultiFun: Metabolism 1.5.3.2. | Dihydrofolate reductase type I; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | 0.654 |
| folB | folC | BPEN_062 | BPEN_510 | Dihydroneopterin aldolase, also has dihydroneopterin triphosphate; Ortholog to Escherichia coli bnum: b3058; MultiFun: Metabolism 1.5.3.2. | Folylpolyglutamate synthase; Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10- formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives. | 0.800 |
| folB | folE | BPEN_062 | BPEN_487 | Dihydroneopterin aldolase, also has dihydroneopterin triphosphate; Ortholog to Escherichia coli bnum: b3058; MultiFun: Metabolism 1.5.3.2. | GTP cyclohydrolase I; Ortholog to Escherichia coli bnum: b2153; MultiFun: Metabolism 1.5.3.2. | 0.949 |
| folB | folK | BPEN_062 | BPEN_155 | Dihydroneopterin aldolase, also has dihydroneopterin triphosphate; Ortholog to Escherichia coli bnum: b3058; MultiFun: Metabolism 1.5.3.2. | 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase; Ortholog to Escherichia coli bnum: b0142; MultiFun: Metabolism 1.5.3.2. | 0.995 |
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