node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ribB | ribD | BPEN_067 | BPEN_240 | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | Pyrimidine deaminase/reductase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.996 |
ribB | ribE | BPEN_067 | BPEN_377 | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | Riboflavin synthase, alpha chain; Ortholog to Escherichia coli bnum: b1662; MultiFun: Metabolism 1.5.3.9. | 0.994 |
ribB | ribH | BPEN_067 | BPEN_241 | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family. | 0.993 |
ribD | ribB | BPEN_240 | BPEN_067 | Pyrimidine deaminase/reductase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | 0.996 |
ribD | ribE | BPEN_240 | BPEN_377 | Pyrimidine deaminase/reductase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Riboflavin synthase, alpha chain; Ortholog to Escherichia coli bnum: b1662; MultiFun: Metabolism 1.5.3.9. | 0.999 |
ribD | ribF | BPEN_240 | BPEN_121 | Pyrimidine deaminase/reductase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Bifunctional: flavokinase; Ortholog to Escherichia coli bnum: b0025; MultiFun: Metabolism 1.5.3.9; Belongs to the ribF family. | 0.751 |
ribD | ribH | BPEN_240 | BPEN_241 | Pyrimidine deaminase/reductase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family. | 0.996 |
ribD | yigB | BPEN_240 | BPEN_599 | Pyrimidine deaminase/reductase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Putative hydrolase of the HAD superfamily; Ortholog to Escherichia coli bnum: b3812. | 0.967 |
ribE | ribB | BPEN_377 | BPEN_067 | Riboflavin synthase, alpha chain; Ortholog to Escherichia coli bnum: b1662; MultiFun: Metabolism 1.5.3.9. | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | 0.994 |
ribE | ribD | BPEN_377 | BPEN_240 | Riboflavin synthase, alpha chain; Ortholog to Escherichia coli bnum: b1662; MultiFun: Metabolism 1.5.3.9. | Pyrimidine deaminase/reductase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.999 |
ribE | ribF | BPEN_377 | BPEN_121 | Riboflavin synthase, alpha chain; Ortholog to Escherichia coli bnum: b1662; MultiFun: Metabolism 1.5.3.9. | Bifunctional: flavokinase; Ortholog to Escherichia coli bnum: b0025; MultiFun: Metabolism 1.5.3.9; Belongs to the ribF family. | 0.937 |
ribE | ribH | BPEN_377 | BPEN_241 | Riboflavin synthase, alpha chain; Ortholog to Escherichia coli bnum: b1662; MultiFun: Metabolism 1.5.3.9. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family. | 0.998 |
ribE | yigB | BPEN_377 | BPEN_599 | Riboflavin synthase, alpha chain; Ortholog to Escherichia coli bnum: b1662; MultiFun: Metabolism 1.5.3.9. | Putative hydrolase of the HAD superfamily; Ortholog to Escherichia coli bnum: b3812. | 0.901 |
ribF | ribD | BPEN_121 | BPEN_240 | Bifunctional: flavokinase; Ortholog to Escherichia coli bnum: b0025; MultiFun: Metabolism 1.5.3.9; Belongs to the ribF family. | Pyrimidine deaminase/reductase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.751 |
ribF | ribE | BPEN_121 | BPEN_377 | Bifunctional: flavokinase; Ortholog to Escherichia coli bnum: b0025; MultiFun: Metabolism 1.5.3.9; Belongs to the ribF family. | Riboflavin synthase, alpha chain; Ortholog to Escherichia coli bnum: b1662; MultiFun: Metabolism 1.5.3.9. | 0.937 |
ribF | ribH | BPEN_121 | BPEN_241 | Bifunctional: flavokinase; Ortholog to Escherichia coli bnum: b0025; MultiFun: Metabolism 1.5.3.9; Belongs to the ribF family. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family. | 0.837 |
ribF | yigB | BPEN_121 | BPEN_599 | Bifunctional: flavokinase; Ortholog to Escherichia coli bnum: b0025; MultiFun: Metabolism 1.5.3.9; Belongs to the ribF family. | Putative hydrolase of the HAD superfamily; Ortholog to Escherichia coli bnum: b3812. | 0.913 |
ribH | ribB | BPEN_241 | BPEN_067 | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family. | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | 0.993 |
ribH | ribD | BPEN_241 | BPEN_240 | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family. | Pyrimidine deaminase/reductase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.996 |
ribH | ribE | BPEN_241 | BPEN_377 | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family. | Riboflavin synthase, alpha chain; Ortholog to Escherichia coli bnum: b1662; MultiFun: Metabolism 1.5.3.9. | 0.998 |