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yjgP yjgP yjgQ yjgQ yhbG yhbG yhbN yhbN yrbK yrbK yrbA yrbA yhcB yhcB yjeP yjeP ytfM ytfM ytfN ytfN imp imp yfiO yfiO ygfE ygfE yaeT yaeT ytfF ytfF rlpB rlpB tolQ tolQ tolR tolR tolA tolA tolB tolB pal pal ybgF ybgF lolB lolB lpp lpp lolA lolA oprC oprC lolE lolE lolD lolD lolC lolC ycfM ycfM yccV yccV yciC yciC tonB tonB hns hns dsbB dsbB yceL yceL yeeX yeeX omp omp BPEN_535 BPEN_535 smpA smpA dsbA dsbA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
yjgPPutative transmembrane protein, transport; Ortholog to Escherichia coli bnum: b4261; MultiFun: Cell structure 6.1; Transport 4. (373 aa)
yjgQPutative transmembrane protein, transport; Ortholog to Escherichia coli bnum: b4262; MultiFun: Cell structure 6.1. (357 aa)
yhbGPutative transport protein (ABC superfamily, atp_bind); Ortholog to Escherichia coli bnum: b3201; MultiFun: Transport 4.3.A.1.a. (241 aa)
yhbNPutative transport protein (ABC superfamily, peri_bind); Ortholog to Escherichia coli bnum: b3200; MultiFun: Transport 4.3.A.1.p. (169 aa)
yrbKPossible exported protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. Belongs to the LptC family. (205 aa)
yrbAPutative transcriptional regulator (BolA family); Ortholog to Escherichia coli bnum: b3190; MultiFun: Regulation 3.1.2; Belongs to the BolA/IbaG family. (89 aa)
yhcBConserved hypothetical protein; Ortholog to Escherichia coli bnum: b3233. (132 aa)
yjePPutative membrane protein; Ortholog to Escherichia coli bnum: b4159; MultiFun: Transport 4.9.B. (1130 aa)
ytfMPutative outer membrane protein; Ortholog to E. coli bnum: b4220; in-frame premature UAG termination codon is located within the ytfM sequence, and a -1 frameshift would be required for synthesis of ytfM; RNA polymerase or ribosomal slippage; possible young pseudogene; MultiFun: Cell structure 6.1. (587 aa)
ytfNPutative exported protein; Ortholog to Escherichia coli bnum: b4221. (1279 aa)
impOrganic solvent tolerance protein precursor; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. (782 aa)
yfiOPutative lipoprotein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamA, the core component of the assembly machinery. (247 aa)
ygfEConserved hypothetical protein; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division. (114 aa)
yaeTOuter membrane protein precursor; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamD, the core component of the assembly machinery. (807 aa)
ytfFPutative cationic amino acid transport protein; Ortholog to Escherichia coli bnum: b4210; MultiFun: Transport 4, 4.S.12. (313 aa)
rlpBRare lipoprotein B precursor; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane. (187 aa)
tolQTolQ; Inner membrane protein required for outer membrane integrity, uptake of group A colicins and phage DNA; ortholog to Escherichia coli bnum: b0737; MultiFun: Cell structure 6.1. (249 aa)
tolRTolR; Role in outer membrane integrity, uptake of group A colicins (TonB-independent), and phage DNA; ortholog to Escherichia coli bnum: b0738; MultiFun: Cell structure 6.1. (141 aa)
tolATolA; Required for outer membrane integrity, uptake of group A colicins, role in translocation of filamenous phage DNA to cytoplasm, role in surface expression of O-antigen; ortholog to Escherichia coli bnum: b0739; MultiFun: Cell structure 6.1; Metabolism 1.6.3.1. (394 aa)
tolBTolB; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. TolB occupies a key intermediary position in the Tol-Pal system because it communicates directly with both membrane-embedded components, Pal in the outer membrane and TolA in the inner membrane. (453 aa)
palPal; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. (175 aa)
ybgFPutative periplasmic protein; Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division; Belongs to the CpoB family. (261 aa)
lolBOuter membrane lipoprotein precursor; Ortholog to Escherichia coli bnum: b1209; MultiFun: Cell structure 6.1. (205 aa)
lppMurein lipoprotein; Ortholog to Escherichia coli bnum: b1677; MultiFun: Cell structure 6.1, 6.2; Metabolism 1.6.7. (78 aa)
lolALolA; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane). (205 aa)
oprCOprC; Outer membrane protein. (718 aa)
lolETransport protein of outer membrane lipoproteins (ABC superfamily, membrane); Ortholog to Escherichia coli bnum: b1118; MultiFun: Cell structure 6.1; Transport 4.3.A.1.m, 4.S.106. (411 aa)
lolDTransport protein of outer membrane lipoproteins (ABC superfamily, atp_bind); Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner. (233 aa)
lolCTransport protein of outer membrane lipoproteins (ABC superfamily, membrane); Ortholog to Escherichia coli bnum: b1116; MultiFun: Cell structure 6.1; Transport 4.3.A.1.m, 4.S.106. (401 aa)
ycfMPutative fibronectin-binding protein; Ortholog to Escherichia coli bnum: b1105. (178 aa)
yccVConserved hypothetical protein; Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress; Belongs to the HspQ family. (105 aa)
yciCPutative membrane protein, transport; Ortholog to Escherichia coli bnum: b1255; MultiFun: Cell structure 6.1. (245 aa)
tonBEnergy transducer; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family. (242 aa)
hnsDNA-binding protein HLP-II (HU, BH2, HD, NS); Ortholog to Escherichia coli bnum: b1237; MultiFun: Cell processes 5.3; Cell structure 6.4; Information transfer 2.2.2, 2.3.7; Regulation 3.1.2; Belongs to the histone-like protein H-NS family. (136 aa)
dsbBDisulfide bond formation protein B; Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein; Belongs to the DsbB family. (174 aa)
yceLPutative membrane transporter (MFS family); Ortholog to Escherichia coli bnum: b1065; MultiFun: Cell processes 5.6.4; Cell structure 6.1; Transport 4.2.A.1, 4.S.126. (407 aa)
yeeXConserved hypothetical protein; Ortholog to Escherichia coli bnum: b2007; Belongs to the UPF0265 family. (107 aa)
ompOuter membrane protein; Ortholog to Escherichia coli bnum: b2215; MultiFun: Cell structure 6.1; Transport 4.1.B.1, 4.S.92. (373 aa)
BPEN_535Conserved hypothetical protein (NT02BF0496). (103 aa)
smpASmall membrane protein A; Ortholog to Escherichia coli bnum: b2617; MultiFun: Cell structure 6.1. (112 aa)
dsbAPeriplasmic protein disulfide isomerase I, disulfide bond formation; Ortholog to Escherichia coli bnum: b3860; MultiFun: Cell processes 5.5; Information transfer 2.3.4. (209 aa)
Your Current Organism:
Blochmannia pennsylvanicus
NCBI taxonomy Id: 291272
Other names: C. Blochmannia pennsylvanicus str. BPEN, Candidatus Blochmannia pennsylvanicus BPEN, Candidatus Blochmannia pennsylvanicus str. BPEN, Candidatus Blochmannia pennsylvanicus strain BPEN
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