(18 nodes) THO complex, and poly(A)+ mRNA export from nucleus network (Vombatus ursinus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	THOC6	THO complex 6. (388 aa)
	NXF1	Uncharacterized protein. (624 aa)
	DDX39B	Uncharacterized protein. (428 aa)
	THOC2	Uncharacterized protein. (1601 aa)
	THOC7	Uncharacterized protein. (204 aa)
	POLDIP3	RRM domain-containing protein. (418 aa)
	ALYREF	Aly/REF export factor. (294 aa)
	LOC114031894	Death domain-containing protein. (658 aa)
	THOC5	Uncharacterized protein. (683 aa)
	ENSVURP00010019799	Uncharacterized protein. (202 aa)
	ENSVURP00010022122	Uncharacterized protein. (1093 aa)
	LOC114031469	Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (156 aa)
	ENSVURP00010023819	WD_REPEATS_REGION domain-containing protein. (344 aa)
	SRSF6	Uncharacterized protein. (341 aa)
	ENSVURP00010027585	Uncharacterized protein. (214 aa)
	ENSVURP00010030333	annotation not available (658 aa)
	SARNP	SAP domain-containing protein. (210 aa)
	DDX39A	Uncharacterized protein. (427 aa)

Your Current Organism:

Vombatus ursinus

NCBI taxonomy Id: 29139
Other names: V. ursinus, coarse-haired wombat, common wombat

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALYREF	DDX39A	ENSVURP00010011246	ENSVURP00010031756	Aly/REF export factor.	Uncharacterized protein.	0.997
ALYREF	DDX39B	ENSVURP00010011246	ENSVURP00010002353	Aly/REF export factor.	Uncharacterized protein.	0.998
ALYREF	ENSVURP00010019799	ENSVURP00010011246	ENSVURP00010019799	Aly/REF export factor.	Uncharacterized protein.	0.953
ALYREF	ENSVURP00010022122	ENSVURP00010011246	ENSVURP00010022122	Aly/REF export factor.	Uncharacterized protein.	0.996
ALYREF	ENSVURP00010023819	ENSVURP00010011246	ENSVURP00010023819	Aly/REF export factor.	WD_REPEATS_REGION domain-containing protein.	0.993
ALYREF	ENSVURP00010027585	ENSVURP00010011246	ENSVURP00010027585	Aly/REF export factor.	Uncharacterized protein.	0.953
ALYREF	ENSVURP00010030333	ENSVURP00010011246	ENSVURP00010030333	Aly/REF export factor.	annotation not available	0.991
ALYREF	LOC114031469	ENSVURP00010011246	ENSVURP00010023366	Aly/REF export factor.	Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...]	0.978
ALYREF	LOC114031894	ENSVURP00010011246	ENSVURP00010013419	Aly/REF export factor.	Death domain-containing protein.	0.991
ALYREF	NXF1	ENSVURP00010011246	ENSVURP00010001723	Aly/REF export factor.	Uncharacterized protein.	0.999
ALYREF	POLDIP3	ENSVURP00010011246	ENSVURP00010010287	Aly/REF export factor.	RRM domain-containing protein.	0.881
ALYREF	SARNP	ENSVURP00010011246	ENSVURP00010031062	Aly/REF export factor.	SAP domain-containing protein.	0.997
ALYREF	SRSF6	ENSVURP00010011246	ENSVURP00010025608	Aly/REF export factor.	Uncharacterized protein.	0.978
ALYREF	THOC2	ENSVURP00010011246	ENSVURP00010005604	Aly/REF export factor.	Uncharacterized protein.	0.996
ALYREF	THOC5	ENSVURP00010011246	ENSVURP00010013539	Aly/REF export factor.	Uncharacterized protein.	0.991
ALYREF	THOC6	ENSVURP00010011246	ENSVURP00010000463	Aly/REF export factor.	THO complex 6.	0.977
ALYREF	THOC7	ENSVURP00010011246	ENSVURP00010007814	Aly/REF export factor.	Uncharacterized protein.	0.953
DDX39A	ALYREF	ENSVURP00010031756	ENSVURP00010011246	Uncharacterized protein.	Aly/REF export factor.	0.997
DDX39A	ENSVURP00010019799	ENSVURP00010031756	ENSVURP00010019799	Uncharacterized protein.	Uncharacterized protein.	0.956
DDX39A	ENSVURP00010022122	ENSVURP00010031756	ENSVURP00010022122	Uncharacterized protein.	Uncharacterized protein.	0.983