(97 nodes) Glycolysis, and Pentose phosphate pathway network (Vombatus ursinus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSVURP00010000485	6PF2K domain-containing protein. (409 aa)
	PARP8	Poly [ADP-ribose] polymerase. (1006 aa)
	ENSVURP00010001019	annotation not available (409 aa)
	ENO3	Uncharacterized protein. (434 aa)
	HK3	Uncharacterized protein. (913 aa)
	TPI1	Triosephosphate isomerase. (248 aa)
	ENO2	Uncharacterized protein. (434 aa)
	GCK	Phosphotransferase. (450 aa)
	UBASH3B	Uncharacterized protein. (640 aa)
	MANBA	Uncharacterized protein. (895 aa)
	ALDOB	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (364 aa)
	TKFC	Uncharacterized protein. (578 aa)
	RPE	Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (228 aa)
	TALDO1	Uncharacterized protein. (283 aa)
	PSPH	Uncharacterized protein. (225 aa)
	PGK1	Phosphoglycerate kinase. (417 aa)
	PFKM	ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (782 aa)
	PRPSAP2	Pribosyltran_N domain-containing protein. (369 aa)
	LOC114037604	Phosphoglycerate kinase. (417 aa)
	ENSVURP00010009309	Uncharacterized protein. (108 aa)
	ENSVURP00010009734	Transket_pyr domain-containing protein. (296 aa)
	TIGAR	Uncharacterized protein. (271 aa)
	RPIA	Uncharacterized protein. (317 aa)
	ENSVURP00010010317	Gp_dh_N domain-containing protein. (247 aa)
	ENSVURP00010010463	2-Hacid_dh_C domain-containing protein. (125 aa)
	ENSVURP00010010496	D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (581 aa)
	LOC114042523	Uncharacterized protein. (101 aa)
	G6PC3	acidPPc domain-containing protein. (378 aa)
	PGAM2	Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (255 aa)
	ALDOA	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (424 aa)
	ENSVURP00010011398	Uncharacterized protein. (135 aa)
	FBP1	FBPase domain-containing protein; Belongs to the FBPase class 1 family. (338 aa)
	FBP2	FBPase domain-containing protein; Belongs to the FBPase class 1 family. (343 aa)
	ENSVURP00010011792	Uncharacterized protein. (127 aa)
	ENSVURP00010012605	TRANSKETOLASE_1 domain-containing protein. (136 aa)
	ALDOC	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (364 aa)
	LOC114047017	Glucose-6-phosphate isomerase; Belongs to the GPI family. (554 aa)
	ENSVURP00010014042	Uncharacterized protein. (375 aa)
	PRPSAP1	Pribosyltran_N domain-containing protein. (385 aa)
	ENSVURP00010014402	annotation not available (113 aa)
	LOC114045424	Uncharacterized protein; Belongs to the LDH/MDH superfamily. (319 aa)
	GNE	Epimerase_2 domain-containing protein. (722 aa)
	GRHPR	Glyoxylate and hydroxypyruvate reductase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (322 aa)
	ENSVURP00010015203	Enolase_N domain-containing protein. (154 aa)
	ENSVURP00010015255	Glyceraldehyde-3-phosphate dehydrogenase. (333 aa)
	HK2	Uncharacterized protein. (917 aa)
	MPI	Mannose-6-phosphate isomerase. (461 aa)
	PFKFB2	6PF2K domain-containing protein. (516 aa)
	TKT	TRANSKETOLASE_1 domain-containing protein. (623 aa)
	ENSVURP00010017456	Uncharacterized protein. (400 aa)
	ENSVURP00010017481	FBPase domain-containing protein. (250 aa)
	LOC114040414	Pyruvate kinase; Belongs to the pyruvate kinase family. (585 aa)
	BPGM	Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (259 aa)
	ENSVURP00010017868	Ldh_1_N domain-containing protein. (89 aa)
	PRPS1	Pribosyltran_N domain-containing protein. (333 aa)
	GAPDH	Glyceraldehyde-3-phosphate dehydrogenase. (333 aa)
	ENSVURP00010018829	annotation not available (585 aa)
	HK1	Uncharacterized protein. (919 aa)
	HKDC1	Uncharacterized protein. (917 aa)
	ENSVURP00010019310	Glucose-6-phosphate isomerase; Belongs to the GPI family. (301 aa)
	ENSVURP00010019337	Uncharacterized protein. (349 aa)
	ENSVURP00010019785	Gp_dh_C domain-containing protein. (162 aa)
	ENSVURP00010019786	Pyruvate kinase; Belongs to the pyruvate kinase family. (573 aa)
	PARP6	Poly [ADP-ribose] polymerase. (630 aa)
	PKM	Pyruvate kinase; Belongs to the pyruvate kinase family. (611 aa)
	LOC114026082	Phosphoserine aminotransferase. (370 aa)
	GLYCTK	Uncharacterized protein. (532 aa)
	PFKL	Uncharacterized protein. (726 aa)
	PGAM1	Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (278 aa)
	ENSVURP00010023530	annotation not available (554 aa)
	PFKFB4	6PF2K domain-containing protein. (469 aa)
	RBM45	Uncharacterized protein. (476 aa)
	G6PD	Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (587 aa)
	PFKFB1	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1. (433 aa)
	ENSVURP00010026017	annotation not available (187 aa)
	ADPGK	Uncharacterized protein. (492 aa)
	ENSVURP00010026347	annotation not available (370 aa)
	RBKS	Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (319 aa)
	G6PC2	Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (355 aa)
	GCKR	Glucokinase regulator. (626 aa)
	KHK	Uncharacterized protein. (343 aa)
	TKTL2	TRANSKETOLASE_1 domain-containing protein. (625 aa)
	MYCBPAP	Uncharacterized protein. (926 aa)
	ENSVURP00010028008	Uncharacterized protein. (181 aa)
	G6PC	Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (357 aa)
	ENSVURP00010028836	Gp_dh_N domain-containing protein. (281 aa)
	PRPS2	Pribosyltran_N domain-containing protein. (318 aa)
	ENSVURP00010029282	Uncharacterized protein. (409 aa)
	ENSVURP00010030513	Uncharacterized protein. (175 aa)
	ENSVURP00010030726	Gp_dh_N domain-containing protein; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (266 aa)
	PFKP	ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (811 aa)
	ENSVURP00010031228	Ldh_1_C domain-containing protein. (93 aa)
	PGD	6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (483 aa)
	H6PD	Uncharacterized protein. (792 aa)
	LOC114029412	Uncharacterized protein. (457 aa)
	ENSVURP00010031637	Uncharacterized protein. (512 aa)
	PGLS	6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (263 aa)

Your Current Organism:

Vombatus ursinus

NCBI taxonomy Id: 29139
Other names: V. ursinus, coarse-haired wombat, common wombat

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADPGK	ALDOA	ENSVURP00010026140	ENSVURP00010011386	Uncharacterized protein.	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family.	0.876
ADPGK	ALDOB	ENSVURP00010026140	ENSVURP00010003814	Uncharacterized protein.	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family.	0.887
ADPGK	ALDOC	ENSVURP00010026140	ENSVURP00010013725	Uncharacterized protein.	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family.	0.887
ADPGK	ENO2	ENSVURP00010026140	ENSVURP00010002351	Uncharacterized protein.	Uncharacterized protein.	0.549
ADPGK	ENO3	ENSVURP00010026140	ENSVURP00010001886	Uncharacterized protein.	Uncharacterized protein.	0.549
ADPGK	ENSVURP00010000485	ENSVURP00010026140	ENSVURP00010000485	Uncharacterized protein.	6PF2K domain-containing protein.	0.562
ADPGK	ENSVURP00010001019	ENSVURP00010026140	ENSVURP00010001019	Uncharacterized protein.	annotation not available	0.562
ADPGK	ENSVURP00010009734	ENSVURP00010026140	ENSVURP00010009734	Uncharacterized protein.	Transket_pyr domain-containing protein.	0.819
ADPGK	ENSVURP00010011398	ENSVURP00010026140	ENSVURP00010011398	Uncharacterized protein.	Uncharacterized protein.	0.820
ADPGK	ENSVURP00010011792	ENSVURP00010026140	ENSVURP00010011792	Uncharacterized protein.	Uncharacterized protein.	0.908
ADPGK	ENSVURP00010012605	ENSVURP00010026140	ENSVURP00010012605	Uncharacterized protein.	TRANSKETOLASE_1 domain-containing protein.	0.739
ADPGK	ENSVURP00010014042	ENSVURP00010026140	ENSVURP00010014042	Uncharacterized protein.	Uncharacterized protein.	0.818
ADPGK	ENSVURP00010015203	ENSVURP00010026140	ENSVURP00010015203	Uncharacterized protein.	Enolase_N domain-containing protein.	0.549
ADPGK	ENSVURP00010017456	ENSVURP00010026140	ENSVURP00010017456	Uncharacterized protein.	Uncharacterized protein.	0.549
ADPGK	ENSVURP00010017481	ENSVURP00010026140	ENSVURP00010017481	Uncharacterized protein.	FBPase domain-containing protein.	0.848
ADPGK	ENSVURP00010019310	ENSVURP00010026140	ENSVURP00010019310	Uncharacterized protein.	Glucose-6-phosphate isomerase; Belongs to the GPI family.	0.908
ADPGK	ENSVURP00010023530	ENSVURP00010026140	ENSVURP00010023530	Uncharacterized protein.	annotation not available	0.908
ADPGK	ENSVURP00010028008	ENSVURP00010026140	ENSVURP00010028008	Uncharacterized protein.	Uncharacterized protein.	0.876
ADPGK	ENSVURP00010029282	ENSVURP00010026140	ENSVURP00010029282	Uncharacterized protein.	Uncharacterized protein.	0.549
ADPGK	ENSVURP00010030513	ENSVURP00010026140	ENSVURP00010030513	Uncharacterized protein.	Uncharacterized protein.	0.876