(13 nodes) Phosphatidylinositol 3-kinase complex, class I, and Insulin receptor substrate network (Vombatus ursinus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	INSR	Tyrosine-protein kinase receptor. (1374 aa)
	PIK3R5	Uncharacterized protein. (872 aa)
	ENSVURP00010006464	Uncharacterized protein. (1377 aa)
	IRS1	Uncharacterized protein. (1242 aa)
	PIK3CB	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1052 aa)
	PIK3CG	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1103 aa)
	PIK3CA	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	PIK3R2	Uncharacterized protein. (738 aa)
	LOC114024909	Uncharacterized protein. (464 aa)
	PTPN1	Tyrosine-protein phosphatase non-receptor type. (423 aa)
	PIK3R1	Uncharacterized protein. (725 aa)
	ENSVURP00010029406	IRS-type PTB domain-containing protein. (1133 aa)
	PIK3CD	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1075 aa)

Your Current Organism:

Vombatus ursinus

NCBI taxonomy Id: 29139
Other names: V. ursinus, coarse-haired wombat, common wombat

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSVURP00010006464	INSR	ENSVURP00010006464	ENSVURP00010001213	Uncharacterized protein.	Tyrosine-protein kinase receptor.	0.986
ENSVURP00010006464	IRS1	ENSVURP00010006464	ENSVURP00010009086	Uncharacterized protein.	Uncharacterized protein.	0.898
ENSVURP00010006464	LOC114024909	ENSVURP00010006464	ENSVURP00010022548	Uncharacterized protein.	Uncharacterized protein.	0.982
ENSVURP00010006464	PIK3CA	ENSVURP00010006464	ENSVURP00010016429	Uncharacterized protein.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.976
ENSVURP00010006464	PIK3CB	ENSVURP00010006464	ENSVURP00010011407	Uncharacterized protein.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.969
ENSVURP00010006464	PIK3CD	ENSVURP00010006464	ENSVURP00010031571	Uncharacterized protein.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.968
ENSVURP00010006464	PIK3CG	ENSVURP00010006464	ENSVURP00010013835	Uncharacterized protein.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.968
ENSVURP00010006464	PIK3R1	ENSVURP00010006464	ENSVURP00010025486	Uncharacterized protein.	Uncharacterized protein.	0.988
ENSVURP00010006464	PIK3R2	ENSVURP00010006464	ENSVURP00010019570	Uncharacterized protein.	Uncharacterized protein.	0.982
ENSVURP00010006464	PIK3R5	ENSVURP00010006464	ENSVURP00010005783	Uncharacterized protein.	Uncharacterized protein.	0.871
ENSVURP00010006464	PTPN1	ENSVURP00010006464	ENSVURP00010024638	Uncharacterized protein.	Tyrosine-protein phosphatase non-receptor type.	0.923
ENSVURP00010029406	INSR	ENSVURP00010029406	ENSVURP00010001213	IRS-type PTB domain-containing protein.	Tyrosine-protein kinase receptor.	0.986
ENSVURP00010029406	IRS1	ENSVURP00010029406	ENSVURP00010009086	IRS-type PTB domain-containing protein.	Uncharacterized protein.	0.898
ENSVURP00010029406	LOC114024909	ENSVURP00010029406	ENSVURP00010022548	IRS-type PTB domain-containing protein.	Uncharacterized protein.	0.982
ENSVURP00010029406	PIK3CA	ENSVURP00010029406	ENSVURP00010016429	IRS-type PTB domain-containing protein.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.976
ENSVURP00010029406	PIK3CB	ENSVURP00010029406	ENSVURP00010011407	IRS-type PTB domain-containing protein.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.969
ENSVURP00010029406	PIK3CD	ENSVURP00010029406	ENSVURP00010031571	IRS-type PTB domain-containing protein.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.968
ENSVURP00010029406	PIK3CG	ENSVURP00010029406	ENSVURP00010013835	IRS-type PTB domain-containing protein.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.968
ENSVURP00010029406	PIK3R1	ENSVURP00010029406	ENSVURP00010025486	IRS-type PTB domain-containing protein.	Uncharacterized protein.	0.988
ENSVURP00010029406	PIK3R2	ENSVURP00010029406	ENSVURP00010019570	IRS-type PTB domain-containing protein.	Uncharacterized protein.	0.982