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ALDH8A1 | Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (487 aa) | ||||
HPD | 4-hydroxyphenylpyruvate dioxygenase. (356 aa) | ||||
MPST | Sulfurtransferase. (294 aa) | ||||
TST | Sulfurtransferase. (298 aa) | ||||
FARS2 | Phenylalanyl-tRNA synthetase 2, mitochondrial. (438 aa) | ||||
YARS2 | Tyrosine--tRNA ligase. (478 aa) | ||||
ENSVURP00010005608 | Uncharacterized protein. (651 aa) | ||||
ENSVURP00010000024 | Uncharacterized protein. (433 aa) | ||||
ENSVURP00010000075 | Uncharacterized protein. (133 aa) | ||||
AARS1 | AA_TRNA_LIGASE_II_ALA domain-containing protein; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain. Belongs to the class-II aminoacyl-tRNA synthetase family. (968 aa) | ||||
ENSVURP00010000180 | 3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. (304 aa) | ||||
HAAO | 3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate; Belongs to the 3-HAO family. (286 aa) | ||||
LOC114043153 | AA_TRNA_LIGASE_II domain-containing protein. (717 aa) | ||||
ASNS | Glutamine amidotransferase type-2 domain-containing protein. (561 aa) | ||||
GOT2 | Aspartate aminotransferase. (429 aa) | ||||
ENSVURP00010001005 | Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (213 aa) | ||||
ENSVURP00010001014 | annotation not available (213 aa) | ||||
DPYD | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. (1025 aa) | ||||
ALDH5A1 | Succinate-semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (537 aa) | ||||
ALDH18A1 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. (801 aa) | ||||
PLOD3 | Fe2OG dioxygenase domain-containing protein. (768 aa) | ||||
AGMAT | Uncharacterized protein; Belongs to the arginase family. (395 aa) | ||||
DBT | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (483 aa) | ||||
TMEM179B | Uncharacterized protein. (219 aa) | ||||
VARS2 | Uncharacterized protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (1058 aa) | ||||
OTC | Uncharacterized protein; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. (354 aa) | ||||
IYD | Nitroreductase domain-containing protein. (288 aa) | ||||
PYCR3 | Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family. (329 aa) | ||||
RARS1 | Uncharacterized protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (661 aa) | ||||
ASRGL1 | Uncharacterized protein. (347 aa) | ||||
DDAH2 | Uncharacterized protein. (286 aa) | ||||
SLC1A3 | Amino acid transporter. (542 aa) | ||||
QDPR | Uncharacterized protein. (243 aa) | ||||
VARS1 | GST C-terminal domain-containing protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (1264 aa) | ||||
TTC36 | TPR_REGION domain-containing protein. (199 aa) | ||||
ATF4 | BZIP domain-containing protein. (349 aa) | ||||
HGD | Uncharacterized protein. (446 aa) | ||||
WARS1 | WHEP-TRS domain-containing protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (476 aa) | ||||
ENSVURP00010004094 | 2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). (437 aa) | ||||
NARS1 | AA_TRNA_LIGASE_II domain-containing protein. (559 aa) | ||||
CPS1 | Uncharacterized protein. (1499 aa) | ||||
GCAT | Aminotran_1_2 domain-containing protein. (425 aa) | ||||
MMUT | B12-binding domain-containing protein. (762 aa) | ||||
ENSVURP00010004950 | SHMT domain-containing protein. (51 aa) | ||||
ILVBL | Uncharacterized protein; Belongs to the TPP enzyme family. (626 aa) | ||||
ENSVURP00010032329 | Aminotran_1_2 domain-containing protein. (484 aa) | ||||
LOC114039868 | Aminotran_1_2 domain-containing protein. (494 aa) | ||||
THNSL1 | Thr_synth_N domain-containing protein. (744 aa) | ||||
GAD2 | Uncharacterized protein. (586 aa) | ||||
OAT | Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (439 aa) | ||||
LRRC47 | B3_4 domain-containing protein. (580 aa) | ||||
ICMT | Protein-S-isoprenylcysteine O-methyltransferase. (280 aa) | ||||
AMDHD1 | Amidohydro-rel domain-containing protein. (441 aa) | ||||
HAL | Histidine ammonia-lyase; Belongs to the PAL/histidase family. (664 aa) | ||||
MRI1 | Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily. (358 aa) | ||||
FTCD | Uncharacterized protein. (541 aa) | ||||
MTHFR | Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (692 aa) | ||||
LOC114029507 | Uncharacterized protein. (406 aa) | ||||
LOC114029426 | Uncharacterized protein. (406 aa) | ||||
ENSVURP00010031323 | BH4_AAA_HYDROXYL_2 domain-containing protein. (391 aa) | ||||
PAH | Uncharacterized protein. (449 aa) | ||||
ENSVURP00010031269 | annotation not available (155 aa) | ||||
ENSVURP00010031265 | Uncharacterized protein. (155 aa) | ||||
ENSVURP00010031183 | B3_4 domain-containing protein. (578 aa) | ||||
AASS | Uncharacterized protein. (925 aa) | ||||
GLS2 | Glutaminase 2. (595 aa) | ||||
PRODH2 | Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate. (480 aa) | ||||
ARG2 | Arginase. (353 aa) | ||||
ARG1 | Arginase. (315 aa) | ||||
ENSVURP00010030502 | AA_TRNA_LIGASE_II domain-containing protein. (541 aa) | ||||
CBS | Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (554 aa) | ||||
SHMT2 | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (504 aa) | ||||
ENSVURP00010030282 | annotation not available (443 aa) | ||||
HMGCL | Pyruvate carboxyltransferase domain-containing protein. (328 aa) | ||||
MARS1 | Uncharacterized protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (907 aa) | ||||
ENSVURP00010030030 | AA_TRNA_LIGASE_II domain-containing protein. (448 aa) | ||||
CTPS2 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (592 aa) | ||||
ENSVURP00010029505 | annotation not available (574 aa) | ||||
LARS2 | Uncharacterized protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (903 aa) | ||||
ACAD8 | Uncharacterized protein. (415 aa) | ||||
AARSD1 | AA_TRNA_LIGASE_II_ALA domain-containing protein. (413 aa) | ||||
MTRR | Uncharacterized protein. (697 aa) | ||||
MECP2 | Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (501 aa) | ||||
THAP4 | THAP-type domain-containing protein. (574 aa) | ||||
ENSVURP00010027656 | Uncharacterized protein. (537 aa) | ||||
LOC114027197 | Aminotran_1_2 domain-containing protein. (385 aa) | ||||
ENSVURP00010027385 | Uncharacterized protein. (209 aa) | ||||
AGXT | Serine--pyruvate aminotransferase. (392 aa) | ||||
ENSVURP00010027255 | Uncharacterized protein. (474 aa) | ||||
ENSVURP00010027089 | annotation not available (467 aa) | ||||
CAD | Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. (2220 aa) | ||||
DPEP1 | Dipeptidase; Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family. (411 aa) | ||||
UPB1 | CN hydrolase domain-containing protein. (384 aa) | ||||
ENSVURP00010026933 | Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate. (591 aa) | ||||
DGLUCY | DUF4392 domain-containing protein. (602 aa) | ||||
ENSVURP00010026347 | annotation not available (370 aa) | ||||
GAD1 | Uncharacterized protein. (593 aa) | ||||
TAT | Tyrosine aminotransferase; Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate. (454 aa) | ||||
LOC114030879 | Lysine--tRNA ligase. (613 aa) | ||||
ENSVURP00010026097 | Uncharacterized protein. (71 aa) | ||||
YARS1 | Tyrosine--tRNA ligase. (528 aa) | ||||
AZIN2 | Uncharacterized protein; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (456 aa) | ||||
GFPT2 | Uncharacterized protein. (682 aa) | ||||
CTPS1 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (591 aa) | ||||
ENSVURP00010025647 | 3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. (344 aa) | ||||
RIMKLA | ATP-grasp domain-containing protein. (391 aa) | ||||
LOC114044891 | Amine oxidase. (556 aa) | ||||
BHMT2 | Hcy-binding domain-containing protein. (427 aa) | ||||
GCLM | Aldo_ket_red domain-containing protein. (273 aa) | ||||
ENSVURP00010024927 | Uncharacterized protein. (57 aa) | ||||
LOC114025497 | Uncharacterized protein. (327 aa) | ||||
ACADSB | Uncharacterized protein. (434 aa) | ||||
MCCC2 | Uncharacterized protein. (565 aa) | ||||
DALRD3 | DALR_1 domain-containing protein. (555 aa) | ||||
ALDH6A1 | Aldedh domain-containing protein. (536 aa) | ||||
DHFR | DHFR domain-containing protein; Belongs to the dihydrofolate reductase family. (226 aa) | ||||
QARS1 | Uncharacterized protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (774 aa) | ||||
DLST | Lipoyl-binding domain-containing protein. (455 aa) | ||||
AMT | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. (447 aa) | ||||
IARS1 | Uncharacterized protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (1262 aa) | ||||
ASNSD1 | Asparagine synthetase domain-containing protein. (633 aa) | ||||
RIMKLB | Ribosomal modification protein rimK like family member B. (410 aa) | ||||
BCKDK | Protein-serine/threonine kinase. (410 aa) | ||||
HIBCH | 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family. (386 aa) | ||||
SCLY | Uncharacterized protein. (448 aa) | ||||
ENSVURP00010022891 | ANK_REP_REGION domain-containing protein. (93 aa) | ||||
HARS1 | Uncharacterized protein. (511 aa) | ||||
ENSVURP00010022545 | M20_dimer domain-containing protein. (447 aa) | ||||
HARS2 | AA_TRNA_LIGASE_II domain-containing protein. (517 aa) | ||||
ENSVURP00010022295 | annotation not available (1591 aa) | ||||
ENSVURP00010022231 | annotation not available (1003 aa) | ||||
HPDL | Uncharacterized protein. (392 aa) | ||||
GMPS | Uncharacterized protein. (693 aa) | ||||
MARS2 | Methionyl-tRNA synthetase 2, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family. (597 aa) | ||||
GARS1 | Uncharacterized protein. (687 aa) | ||||
FTCDNL1 | FTCD_N domain-containing protein. (325 aa) | ||||
GOT1 | Aspartate aminotransferase. (465 aa) | ||||
ENSVURP00010021564 | Uncharacterized protein. (142 aa) | ||||
NARS2 | AA_TRNA_LIGASE_II domain-containing protein. (484 aa) | ||||
ENSVURP00010021437 | Amine oxidase. (527 aa) | ||||
LOC114026082 | Phosphoserine aminotransferase. (370 aa) | ||||
GLUD1 | ELFV_dehydrog domain-containing protein; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (552 aa) | ||||
ENSVURP00010021214 | Uncharacterized protein. (295 aa) | ||||
ODC1 | Uncharacterized protein; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (461 aa) | ||||
FPGS | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. (589 aa) | ||||
BCAT1 | Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (377 aa) | ||||
HDC | Uncharacterized protein. (655 aa) | ||||
ENSVURP00010020738 | PhetRS_B1 domain-containing protein. (85 aa) | ||||
LOC114052316 | Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (510 aa) | ||||
FARSB | B5 domain-containing protein. (589 aa) | ||||
UROC1 | Uncharacterized protein. (676 aa) | ||||
GSTZ1 | Uncharacterized protein; Belongs to the GST superfamily. (218 aa) | ||||
ENSVURP00010020602 | annotation not available (456 aa) | ||||
TMED8 | GOLD domain-containing protein. (324 aa) | ||||
NOXRED1 | F420_oxidored domain-containing protein. (371 aa) | ||||
SARS1 | AA_TRNA_LIGASE_II domain-containing protein. (514 aa) | ||||
LOC114049669-2 | Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract. (492 aa) | ||||
ENSVURP00010019924 | AA_TRNA_LIGASE_II domain-containing protein. (719 aa) | ||||
AGXT2 | Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (506 aa) | ||||
LOC114036990 | Epimerase domain-containing protein. (372 aa) | ||||
LOC114052429 | MBD domain-containing protein. (476 aa) | ||||
GGT5 | Uncharacterized protein. (572 aa) | ||||
ENSVURP00010019211 | Aminotran_1_2 domain-containing protein. (174 aa) | ||||
SLC25A44 | Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (314 aa) | ||||
LOC114054079 | Fe-ADH domain-containing protein. (467 aa) | ||||
LOC114042670 | Uncharacterized protein. (306 aa) | ||||
GLYAT | Uncharacterized protein. (322 aa) | ||||
LOC114042405 | PALP domain-containing protein. (545 aa) | ||||
TARS3 | Threonyl-tRNA synthetase like 2. (802 aa) | ||||
IL4I1 | Amine oxidase. (507 aa) | ||||
DDC | Dopa decarboxylase. (490 aa) | ||||
ACAT1 | Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (427 aa) | ||||
AASDHPPT | ACPS domain-containing protein. (298 aa) | ||||
EARS2 | Glutamyl-tRNA synthetase 2, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family. (523 aa) | ||||
ENSVURP00010018096 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1253 aa) | ||||
SMIM36 | Small integral membrane protein 36. (93 aa) | ||||
ENSVURP00010017639 | annotation not available (562 aa) | ||||
KYAT1 | Aminotran_1_2 domain-containing protein. (456 aa) | ||||
ENSVURP00010017425 | Carboxyl_trans domain-containing protein. (335 aa) | ||||
CTH | Uncharacterized protein. (398 aa) | ||||
ETFA | ETF domain-containing protein. (357 aa) | ||||
ENSVURP00010016892 | Uncharacterized protein. (346 aa) | ||||
GPT2 | Glutamic--pyruvic transaminase 2. (474 aa) | ||||
ENSVURP00010016838 | Isocitrate dehydrogenase [NAD] subunit, mitochondrial. (366 aa) | ||||
ASS1 | Uncharacterized protein. (438 aa) | ||||
CARS1 | tRNA-synt_1e domain-containing protein. (831 aa) | ||||
PM20D1 | M20_dimer domain-containing protein. (524 aa) | ||||
FARSA | AA_TRNA_LIGASE_II domain-containing protein. (497 aa) | ||||
GCDH | Uncharacterized protein. (429 aa) | ||||
TDO2 | Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. (407 aa) | ||||
PCBD1 | Uncharacterized protein. (104 aa) | ||||
NIT2 | CN hydrolase domain-containing protein. (286 aa) | ||||
GFPT1 | Uncharacterized protein. (699 aa) | ||||
TH | BH4_AAA_HYDROXYL_2 domain-containing protein. (496 aa) | ||||
GATB | Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). Belongs to the GatB/GatE family. GatB subfamily. (547 aa) | ||||
APIP | Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway, which plays a key role in cancer, apoptosis, microbial proliferation and inflammation. May inhibit the CASP1-related inflammatory response (pyroptosis), the CASP9-dependent apoptotic pathway and the cytochrome c-dependent and APAF1-mediated cell death; Belongs to the aldolase class II family. MtnB subfamily. (243 aa) | ||||
SARDH | Sarcosine dehydrogenase. (893 aa) | ||||
MCCC1 | Uncharacterized protein. (751 aa) | ||||
ENSVURP00010015002 | Aminotran_1_2 domain-containing protein. (535 aa) | ||||
ACCS | Aminotran_1_2 domain-containing protein. (502 aa) | ||||
ENSVURP00010014933 | Uncharacterized protein. (70 aa) | ||||
ENSVURP00010014409 | Uncharacterized protein. (59 aa) | ||||
PPAT | Amidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (518 aa) | ||||
AASDH | Carrier domain-containing protein. (1115 aa) | ||||
ENSVURP00010014308 | Uncharacterized protein. (59 aa) | ||||
DDO | DAO domain-containing protein. (341 aa) | ||||
NOS2 | Nitric oxide synthase; Produces nitric oxide (NO). (1153 aa) | ||||
BCAT2 | Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (432 aa) | ||||
LOC114031842 | MR_MLE domain-containing protein. (443 aa) | ||||
PLOD2 | Fe2OG dioxygenase domain-containing protein. (758 aa) | ||||
HMGCLL1 | Pyruvate carboxyltransferase domain-containing protein. (339 aa) | ||||
AFMID | Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites. (302 aa) | ||||
ENOPH1 | Enolase-phosphatase E1; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). (260 aa) | ||||
GOT1L1 | Aminotran_1_2 domain-containing protein. (411 aa) | ||||
CDO1 | Cysteine dioxygenase. (200 aa) | ||||
SHMT1 | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (484 aa) | ||||
LOC114049648 | Uncharacterized protein. (1591 aa) | ||||
QRSL1 | Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). Belongs to the amidase family. GatA subfamily. (527 aa) | ||||
LOC114049892 | Uncharacterized protein. (1003 aa) | ||||
ADI1 | 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Also down-regulates cell migration mediated by MMP14. Belongs to the acireductone dioxygenase (ARD) family. (179 aa) | ||||
GLUL | Glutamine synthetase. (373 aa) | ||||
PIPOX | Pipecolic acid and sarcosine oxidase. (387 aa) | ||||
ABAT | Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (500 aa) | ||||
IDO1 | Uncharacterized protein. (399 aa) | ||||
IDO2 | Uncharacterized protein. (419 aa) | ||||
DDAH1 | Uncharacterized protein. (285 aa) | ||||
GCLC | Uncharacterized protein. (637 aa) | ||||
BLMH | Bleomycin hydrolase; Belongs to the peptidase C1 family. (458 aa) | ||||
ENSVURP00010011731 | Uncharacterized protein. (269 aa) | ||||
LARS1 | Uncharacterized protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (1176 aa) | ||||
ETFB | ETF domain-containing protein. (255 aa) | ||||
AADAT | Aminotran_1_2 domain-containing protein. (425 aa) | ||||
PYCR1 | Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family. (320 aa) | ||||
NAGS | N-acetyltransferase domain-containing protein. (548 aa) | ||||
WARS2 | Uncharacterized protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (359 aa) | ||||
IVD | Uncharacterized protein. (422 aa) | ||||
ENSVURP00010010496 | D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (581 aa) | ||||
ENSVURP00010010463 | 2-Hacid_dh_C domain-containing protein. (125 aa) | ||||
THNSL2 | Uncharacterized protein. (481 aa) | ||||
SRR | Serine racemase. (414 aa) | ||||
ADSS | Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (456 aa) | ||||
HAO1 | FMN hydroxy acid dehydrogenase domain-containing protein. (370 aa) | ||||
PCBD2 | Uncharacterized protein. (138 aa) | ||||
NOS3 | Nitric oxide synthase; Produces nitric oxide (NO). (1193 aa) | ||||
ACMSD | 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase; Converts alpha-amino-beta-carboxymuconate-epsilon- semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). Belongs to the metallo-dependent hydrolases superfamily. (336 aa) | ||||
LOC114049669 | Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract. (474 aa) | ||||
PARS2 | AA_TRNA_LIGASE_II domain-containing protein. (497 aa) | ||||
DAO | DAO domain-containing protein. (345 aa) | ||||
AZIN1 | Uncharacterized protein; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (447 aa) | ||||
TPH2 | Uncharacterized protein. (485 aa) | ||||
ENSVURP00010009072 | Iodothyronine deiodinase; Responsible for the deiodination of T4 (3,5,3',5'- tetraiodothyronine). (120 aa) | ||||
DARS1 | AA_TRNA_LIGASE_II domain-containing protein. (563 aa) | ||||
MTAP | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. (283 aa) | ||||
GATC | Glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). Belongs to the GatC family. (156 aa) | ||||
SIRT4 | NAD-dependent protein lipoamidase sirtuin-4, mitochondrial; Acts as NAD-dependent protein lipoamidase, ADP-ribosyl transferase and deacetylase. Catalyzes more efficiently removal of lipoyl- and biotinyl- than acetyl-lysine modifications. Inhibits the pyruvate dehydrogenase complex (PDH) activity via the enzymatic hydrolysis of the lipoamide cofactor from the E2 component, DLAT, in a phosphorylation-independent manner. Catalyzes the transfer of ADP- ribosyl groups onto target proteins, including mitochondrial GLUD1, inhibiting GLUD1 enzyme activity. Acts as a negative regulator of mitoc [...] (352 aa) | ||||
GLDC | Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. (1031 aa) | ||||
TPH1 | Uncharacterized protein. (444 aa) | ||||
GNMT | Glycine N-methyltransferase. (295 aa) | ||||
RARS2 | Arginyl-tRNA synthetase 2, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family. (623 aa) | ||||
FAH | Fumarylacetoacetase. (419 aa) | ||||
ENSVURP00010007668 | annotation not available (1337 aa) | ||||
LOC114034219 | Glutamine amidotransferase type-1 domain-containing protein. (1337 aa) | ||||
NOX4 | FAD-binding FR-type domain-containing protein. (578 aa) | ||||
DARS2 | AA_TRNA_LIGASE_II domain-containing protein. (696 aa) | ||||
KYNU | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. Has a preference for the L-3-hydroxy form. Also has cysteine-conjugate-beta-lyase activity. Belongs to the kynureninase family. (464 aa) | ||||
ASL | Uncharacterized protein. (464 aa) | ||||
ENSVURP00010007187 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1254 aa) | ||||
NOS1 | Nitric oxide synthase; Produces nitric oxide (NO). (1434 aa) | ||||
ENSVURP00010007029 | tRNA-synt_1e domain-containing protein. (574 aa) | ||||
ASPG | Asparaginase. (531 aa) | ||||
PSPH | Uncharacterized protein. (225 aa) | ||||
TARS1 | AA_TRNA_LIGASE_II domain-containing protein. (722 aa) | ||||
ALDH4A1 | Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family. (562 aa) | ||||
BCKDHB | Transket_pyr domain-containing protein. (394 aa) | ||||
SDSL | PALP domain-containing protein. (331 aa) | ||||
SDS | Serine dehydratase. (325 aa) | ||||
AARS2 | AA_TRNA_LIGASE_II_ALA domain-containing protein; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain. Belongs to the class-II aminoacyl-tRNA synthetase family. (990 aa) |