STRINGSTRING
ALDH8A1 ALDH8A1 HPD HPD MPST MPST TST TST FARS2 FARS2 YARS2 YARS2 ENSVURP00010005608 ENSVURP00010005608 ENSVURP00010000024 ENSVURP00010000024 ENSVURP00010000075 ENSVURP00010000075 AARS1 AARS1 ENSVURP00010000180 ENSVURP00010000180 HAAO HAAO LOC114043153 LOC114043153 ASNS ASNS GOT2 GOT2 ENSVURP00010001005 ENSVURP00010001005 ENSVURP00010001014 ENSVURP00010001014 DPYD DPYD ALDH5A1 ALDH5A1 ALDH18A1 ALDH18A1 PLOD3 PLOD3 AGMAT AGMAT DBT DBT TMEM179B TMEM179B VARS2 VARS2 OTC OTC IYD IYD PYCR3 PYCR3 RARS1 RARS1 ASRGL1 ASRGL1 DDAH2 DDAH2 SLC1A3 SLC1A3 QDPR QDPR VARS1 VARS1 TTC36 TTC36 ATF4 ATF4 HGD HGD WARS1 WARS1 ENSVURP00010004094 ENSVURP00010004094 NARS1 NARS1 CPS1 CPS1 GCAT GCAT MMUT MMUT ENSVURP00010004950 ENSVURP00010004950 ILVBL ILVBL ENSVURP00010032329 ENSVURP00010032329 LOC114039868 LOC114039868 THNSL1 THNSL1 GAD2 GAD2 OAT OAT LRRC47 LRRC47 ICMT ICMT AMDHD1 AMDHD1 HAL HAL MRI1 MRI1 FTCD FTCD MTHFR MTHFR LOC114029507 LOC114029507 LOC114029426 LOC114029426 ENSVURP00010031323 ENSVURP00010031323 PAH PAH ENSVURP00010031269 ENSVURP00010031269 ENSVURP00010031265 ENSVURP00010031265 ENSVURP00010031183 ENSVURP00010031183 AASS AASS GLS2 GLS2 PRODH2 PRODH2 ARG2 ARG2 ARG1 ARG1 ENSVURP00010030502 ENSVURP00010030502 CBS CBS SHMT2 SHMT2 ENSVURP00010030282 ENSVURP00010030282 HMGCL HMGCL MARS1 MARS1 ENSVURP00010030030 ENSVURP00010030030 CTPS2 CTPS2 ENSVURP00010029505 ENSVURP00010029505 LARS2 LARS2 ACAD8 ACAD8 AARSD1 AARSD1 MTRR MTRR MECP2 MECP2 THAP4 THAP4 ENSVURP00010027656 ENSVURP00010027656 LOC114027197 LOC114027197 ENSVURP00010027385 ENSVURP00010027385 AGXT AGXT ENSVURP00010027255 ENSVURP00010027255 ENSVURP00010027089 ENSVURP00010027089 CAD CAD DPEP1 DPEP1 UPB1 UPB1 ENSVURP00010026933 ENSVURP00010026933 DGLUCY DGLUCY ENSVURP00010026347 ENSVURP00010026347 GAD1 GAD1 TAT TAT LOC114030879 LOC114030879 ENSVURP00010026097 ENSVURP00010026097 YARS1 YARS1 AZIN2 AZIN2 GFPT2 GFPT2 CTPS1 CTPS1 ENSVURP00010025647 ENSVURP00010025647 RIMKLA RIMKLA LOC114044891 LOC114044891 BHMT2 BHMT2 GCLM GCLM ENSVURP00010024927 ENSVURP00010024927 LOC114025497 LOC114025497 ACADSB ACADSB MCCC2 MCCC2 DALRD3 DALRD3 ALDH6A1 ALDH6A1 DHFR DHFR QARS1 QARS1 DLST DLST AMT AMT IARS1 IARS1 ASNSD1 ASNSD1 RIMKLB RIMKLB BCKDK BCKDK HIBCH HIBCH SCLY SCLY ENSVURP00010022891 ENSVURP00010022891 HARS1 HARS1 ENSVURP00010022545 ENSVURP00010022545 HARS2 HARS2 ENSVURP00010022295 ENSVURP00010022295 ENSVURP00010022231 ENSVURP00010022231 HPDL HPDL GMPS GMPS MARS2 MARS2 GARS1 GARS1 FTCDNL1 FTCDNL1 GOT1 GOT1 ENSVURP00010021564 ENSVURP00010021564 NARS2 NARS2 ENSVURP00010021437 ENSVURP00010021437 LOC114026082 LOC114026082 GLUD1 GLUD1 ENSVURP00010021214 ENSVURP00010021214 ODC1 ODC1 FPGS FPGS BCAT1 BCAT1 HDC HDC ENSVURP00010020738 ENSVURP00010020738 LOC114052316 LOC114052316 FARSB FARSB UROC1 UROC1 GSTZ1 GSTZ1 ENSVURP00010020602 ENSVURP00010020602 TMED8 TMED8 NOXRED1 NOXRED1 SARS1 SARS1 LOC114049669-2 LOC114049669-2 ENSVURP00010019924 ENSVURP00010019924 AGXT2 AGXT2 LOC114036990 LOC114036990 LOC114052429 LOC114052429 GGT5 GGT5 ENSVURP00010019211 ENSVURP00010019211 SLC25A44 SLC25A44 LOC114054079 LOC114054079 LOC114042670 LOC114042670 GLYAT GLYAT LOC114042405 LOC114042405 TARS3 TARS3 IL4I1 IL4I1 DDC DDC ACAT1 ACAT1 AASDHPPT AASDHPPT EARS2 EARS2 ENSVURP00010018096 ENSVURP00010018096 SMIM36 SMIM36 ENSVURP00010017639 ENSVURP00010017639 KYAT1 KYAT1 ENSVURP00010017425 ENSVURP00010017425 CTH CTH ETFA ETFA ENSVURP00010016892 ENSVURP00010016892 GPT2 GPT2 ENSVURP00010016838 ENSVURP00010016838 ASS1 ASS1 CARS1 CARS1 PM20D1 PM20D1 FARSA FARSA GCDH GCDH TDO2 TDO2 PCBD1 PCBD1 NIT2 NIT2 GFPT1 GFPT1 TH TH GATB GATB APIP APIP SARDH SARDH MCCC1 MCCC1 ENSVURP00010015002 ENSVURP00010015002 ACCS ACCS ENSVURP00010014933 ENSVURP00010014933 ENSVURP00010014409 ENSVURP00010014409 PPAT PPAT AASDH AASDH ENSVURP00010014308 ENSVURP00010014308 DDO DDO NOS2 NOS2 BCAT2 BCAT2 LOC114031842 LOC114031842 PLOD2 PLOD2 HMGCLL1 HMGCLL1 AFMID AFMID ENOPH1 ENOPH1 GOT1L1 GOT1L1 CDO1 CDO1 SHMT1 SHMT1 LOC114049648 LOC114049648 QRSL1 QRSL1 LOC114049892 LOC114049892 ADI1 ADI1 GLUL GLUL PIPOX PIPOX ABAT ABAT IDO1 IDO1 IDO2 IDO2 DDAH1 DDAH1 GCLC GCLC BLMH BLMH ENSVURP00010011731 ENSVURP00010011731 LARS1 LARS1 ETFB ETFB AADAT AADAT PYCR1 PYCR1 NAGS NAGS WARS2 WARS2 IVD IVD ENSVURP00010010496 ENSVURP00010010496 ENSVURP00010010463 ENSVURP00010010463 THNSL2 THNSL2 SRR SRR ADSS ADSS HAO1 HAO1 PCBD2 PCBD2 NOS3 NOS3 ACMSD ACMSD LOC114049669 LOC114049669 PARS2 PARS2 DAO DAO AZIN1 AZIN1 TPH2 TPH2 ENSVURP00010009072 ENSVURP00010009072 DARS1 DARS1 MTAP MTAP GATC GATC SIRT4 SIRT4 GLDC GLDC TPH1 TPH1 GNMT GNMT RARS2 RARS2 FAH FAH ENSVURP00010007668 ENSVURP00010007668 LOC114034219 LOC114034219 NOX4 NOX4 DARS2 DARS2 KYNU KYNU ASL ASL ENSVURP00010007187 ENSVURP00010007187 NOS1 NOS1 ENSVURP00010007029 ENSVURP00010007029 ASPG ASPG PSPH PSPH TARS1 TARS1 ALDH4A1 ALDH4A1 BCKDHB BCKDHB SDSL SDSL SDS SDS AARS2 AARS2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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ALDH8A1Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (487 aa)
HPD4-hydroxyphenylpyruvate dioxygenase. (356 aa)
MPSTSulfurtransferase. (294 aa)
TSTSulfurtransferase. (298 aa)
FARS2Phenylalanyl-tRNA synthetase 2, mitochondrial. (438 aa)
YARS2Tyrosine--tRNA ligase. (478 aa)
ENSVURP00010005608Uncharacterized protein. (651 aa)
ENSVURP00010000024Uncharacterized protein. (433 aa)
ENSVURP00010000075Uncharacterized protein. (133 aa)
AARS1AA_TRNA_LIGASE_II_ALA domain-containing protein; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain. Belongs to the class-II aminoacyl-tRNA synthetase family. (968 aa)
ENSVURP000100001803-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. (304 aa)
HAAO3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate; Belongs to the 3-HAO family. (286 aa)
LOC114043153AA_TRNA_LIGASE_II domain-containing protein. (717 aa)
ASNSGlutamine amidotransferase type-2 domain-containing protein. (561 aa)
GOT2Aspartate aminotransferase. (429 aa)
ENSVURP00010001005Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (213 aa)
ENSVURP00010001014annotation not available (213 aa)
DPYDDihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. (1025 aa)
ALDH5A1Succinate-semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (537 aa)
ALDH18A1Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. (801 aa)
PLOD3Fe2OG dioxygenase domain-containing protein. (768 aa)
AGMATUncharacterized protein; Belongs to the arginase family. (395 aa)
DBTDihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (483 aa)
TMEM179BUncharacterized protein. (219 aa)
VARS2Uncharacterized protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (1058 aa)
OTCUncharacterized protein; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. (354 aa)
IYDNitroreductase domain-containing protein. (288 aa)
PYCR3Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family. (329 aa)
RARS1Uncharacterized protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (661 aa)
ASRGL1Uncharacterized protein. (347 aa)
DDAH2Uncharacterized protein. (286 aa)
SLC1A3Amino acid transporter. (542 aa)
QDPRUncharacterized protein. (243 aa)
VARS1GST C-terminal domain-containing protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (1264 aa)
TTC36TPR_REGION domain-containing protein. (199 aa)
ATF4BZIP domain-containing protein. (349 aa)
HGDUncharacterized protein. (446 aa)
WARS1WHEP-TRS domain-containing protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (476 aa)
ENSVURP000100040942-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). (437 aa)
NARS1AA_TRNA_LIGASE_II domain-containing protein. (559 aa)
CPS1Uncharacterized protein. (1499 aa)
GCATAminotran_1_2 domain-containing protein. (425 aa)
MMUTB12-binding domain-containing protein. (762 aa)
ENSVURP00010004950SHMT domain-containing protein. (51 aa)
ILVBLUncharacterized protein; Belongs to the TPP enzyme family. (626 aa)
ENSVURP00010032329Aminotran_1_2 domain-containing protein. (484 aa)
LOC114039868Aminotran_1_2 domain-containing protein. (494 aa)
THNSL1Thr_synth_N domain-containing protein. (744 aa)
GAD2Uncharacterized protein. (586 aa)
OATUncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (439 aa)
LRRC47B3_4 domain-containing protein. (580 aa)
ICMTProtein-S-isoprenylcysteine O-methyltransferase. (280 aa)
AMDHD1Amidohydro-rel domain-containing protein. (441 aa)
HALHistidine ammonia-lyase; Belongs to the PAL/histidase family. (664 aa)
MRI1Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily. (358 aa)
FTCDUncharacterized protein. (541 aa)
MTHFRMethylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (692 aa)
LOC114029507Uncharacterized protein. (406 aa)
LOC114029426Uncharacterized protein. (406 aa)
ENSVURP00010031323BH4_AAA_HYDROXYL_2 domain-containing protein. (391 aa)
PAHUncharacterized protein. (449 aa)
ENSVURP00010031269annotation not available (155 aa)
ENSVURP00010031265Uncharacterized protein. (155 aa)
ENSVURP00010031183B3_4 domain-containing protein. (578 aa)
AASSUncharacterized protein. (925 aa)
GLS2Glutaminase 2. (595 aa)
PRODH2Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate. (480 aa)
ARG2Arginase. (353 aa)
ARG1Arginase. (315 aa)
ENSVURP00010030502AA_TRNA_LIGASE_II domain-containing protein. (541 aa)
CBSCystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (554 aa)
SHMT2Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (504 aa)
ENSVURP00010030282annotation not available (443 aa)
HMGCLPyruvate carboxyltransferase domain-containing protein. (328 aa)
MARS1Uncharacterized protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (907 aa)
ENSVURP00010030030AA_TRNA_LIGASE_II domain-containing protein. (448 aa)
CTPS2CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (592 aa)
ENSVURP00010029505annotation not available (574 aa)
LARS2Uncharacterized protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (903 aa)
ACAD8Uncharacterized protein. (415 aa)
AARSD1AA_TRNA_LIGASE_II_ALA domain-containing protein. (413 aa)
MTRRUncharacterized protein. (697 aa)
MECP2Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (501 aa)
THAP4THAP-type domain-containing protein. (574 aa)
ENSVURP00010027656Uncharacterized protein. (537 aa)
LOC114027197Aminotran_1_2 domain-containing protein. (385 aa)
ENSVURP00010027385Uncharacterized protein. (209 aa)
AGXTSerine--pyruvate aminotransferase. (392 aa)
ENSVURP00010027255Uncharacterized protein. (474 aa)
ENSVURP00010027089annotation not available (467 aa)
CADCarbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. (2220 aa)
DPEP1Dipeptidase; Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family. (411 aa)
UPB1CN hydrolase domain-containing protein. (384 aa)
ENSVURP00010026933Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate. (591 aa)
DGLUCYDUF4392 domain-containing protein. (602 aa)
ENSVURP00010026347annotation not available (370 aa)
GAD1Uncharacterized protein. (593 aa)
TATTyrosine aminotransferase; Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate. (454 aa)
LOC114030879Lysine--tRNA ligase. (613 aa)
ENSVURP00010026097Uncharacterized protein. (71 aa)
YARS1Tyrosine--tRNA ligase. (528 aa)
AZIN2Uncharacterized protein; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (456 aa)
GFPT2Uncharacterized protein. (682 aa)
CTPS1CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (591 aa)
ENSVURP000100256473-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. (344 aa)
RIMKLAATP-grasp domain-containing protein. (391 aa)
LOC114044891Amine oxidase. (556 aa)
BHMT2Hcy-binding domain-containing protein. (427 aa)
GCLMAldo_ket_red domain-containing protein. (273 aa)
ENSVURP00010024927Uncharacterized protein. (57 aa)
LOC114025497Uncharacterized protein. (327 aa)
ACADSBUncharacterized protein. (434 aa)
MCCC2Uncharacterized protein. (565 aa)
DALRD3DALR_1 domain-containing protein. (555 aa)
ALDH6A1Aldedh domain-containing protein. (536 aa)
DHFRDHFR domain-containing protein; Belongs to the dihydrofolate reductase family. (226 aa)
QARS1Uncharacterized protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (774 aa)
DLSTLipoyl-binding domain-containing protein. (455 aa)
AMTAminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. (447 aa)
IARS1Uncharacterized protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (1262 aa)
ASNSD1Asparagine synthetase domain-containing protein. (633 aa)
RIMKLBRibosomal modification protein rimK like family member B. (410 aa)
BCKDKProtein-serine/threonine kinase. (410 aa)
HIBCH3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family. (386 aa)
SCLYUncharacterized protein. (448 aa)
ENSVURP00010022891ANK_REP_REGION domain-containing protein. (93 aa)
HARS1Uncharacterized protein. (511 aa)
ENSVURP00010022545M20_dimer domain-containing protein. (447 aa)
HARS2AA_TRNA_LIGASE_II domain-containing protein. (517 aa)
ENSVURP00010022295annotation not available (1591 aa)
ENSVURP00010022231annotation not available (1003 aa)
HPDLUncharacterized protein. (392 aa)
GMPSUncharacterized protein. (693 aa)
MARS2Methionyl-tRNA synthetase 2, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family. (597 aa)
GARS1Uncharacterized protein. (687 aa)
FTCDNL1FTCD_N domain-containing protein. (325 aa)
GOT1Aspartate aminotransferase. (465 aa)
ENSVURP00010021564Uncharacterized protein. (142 aa)
NARS2AA_TRNA_LIGASE_II domain-containing protein. (484 aa)
ENSVURP00010021437Amine oxidase. (527 aa)
LOC114026082Phosphoserine aminotransferase. (370 aa)
GLUD1ELFV_dehydrog domain-containing protein; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (552 aa)
ENSVURP00010021214Uncharacterized protein. (295 aa)
ODC1Uncharacterized protein; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (461 aa)
FPGSFolylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. (589 aa)
BCAT1Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (377 aa)
HDCUncharacterized protein. (655 aa)
ENSVURP00010020738PhetRS_B1 domain-containing protein. (85 aa)
LOC114052316Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (510 aa)
FARSBB5 domain-containing protein. (589 aa)
UROC1Uncharacterized protein. (676 aa)
GSTZ1Uncharacterized protein; Belongs to the GST superfamily. (218 aa)
ENSVURP00010020602annotation not available (456 aa)
TMED8GOLD domain-containing protein. (324 aa)
NOXRED1F420_oxidored domain-containing protein. (371 aa)
SARS1AA_TRNA_LIGASE_II domain-containing protein. (514 aa)
LOC114049669-2Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract. (492 aa)
ENSVURP00010019924AA_TRNA_LIGASE_II domain-containing protein. (719 aa)
AGXT2Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (506 aa)
LOC114036990Epimerase domain-containing protein. (372 aa)
LOC114052429MBD domain-containing protein. (476 aa)
GGT5Uncharacterized protein. (572 aa)
ENSVURP00010019211Aminotran_1_2 domain-containing protein. (174 aa)
SLC25A44Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (314 aa)
LOC114054079Fe-ADH domain-containing protein. (467 aa)
LOC114042670Uncharacterized protein. (306 aa)
GLYATUncharacterized protein. (322 aa)
LOC114042405PALP domain-containing protein. (545 aa)
TARS3Threonyl-tRNA synthetase like 2. (802 aa)
IL4I1Amine oxidase. (507 aa)
DDCDopa decarboxylase. (490 aa)
ACAT1Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (427 aa)
AASDHPPTACPS domain-containing protein. (298 aa)
EARS2Glutamyl-tRNA synthetase 2, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family. (523 aa)
ENSVURP00010018096Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1253 aa)
SMIM36Small integral membrane protein 36. (93 aa)
ENSVURP00010017639annotation not available (562 aa)
KYAT1Aminotran_1_2 domain-containing protein. (456 aa)
ENSVURP00010017425Carboxyl_trans domain-containing protein. (335 aa)
CTHUncharacterized protein. (398 aa)
ETFAETF domain-containing protein. (357 aa)
ENSVURP00010016892Uncharacterized protein. (346 aa)
GPT2Glutamic--pyruvic transaminase 2. (474 aa)
ENSVURP00010016838Isocitrate dehydrogenase [NAD] subunit, mitochondrial. (366 aa)
ASS1Uncharacterized protein. (438 aa)
CARS1tRNA-synt_1e domain-containing protein. (831 aa)
PM20D1M20_dimer domain-containing protein. (524 aa)
FARSAAA_TRNA_LIGASE_II domain-containing protein. (497 aa)
GCDHUncharacterized protein. (429 aa)
TDO2Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. (407 aa)
PCBD1Uncharacterized protein. (104 aa)
NIT2CN hydrolase domain-containing protein. (286 aa)
GFPT1Uncharacterized protein. (699 aa)
THBH4_AAA_HYDROXYL_2 domain-containing protein. (496 aa)
GATBGlutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). Belongs to the GatB/GatE family. GatB subfamily. (547 aa)
APIPMethylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway, which plays a key role in cancer, apoptosis, microbial proliferation and inflammation. May inhibit the CASP1-related inflammatory response (pyroptosis), the CASP9-dependent apoptotic pathway and the cytochrome c-dependent and APAF1-mediated cell death; Belongs to the aldolase class II family. MtnB subfamily. (243 aa)
SARDHSarcosine dehydrogenase. (893 aa)
MCCC1Uncharacterized protein. (751 aa)
ENSVURP00010015002Aminotran_1_2 domain-containing protein. (535 aa)
ACCSAminotran_1_2 domain-containing protein. (502 aa)
ENSVURP00010014933Uncharacterized protein. (70 aa)
ENSVURP00010014409Uncharacterized protein. (59 aa)
PPATAmidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (518 aa)
AASDHCarrier domain-containing protein. (1115 aa)
ENSVURP00010014308Uncharacterized protein. (59 aa)
DDODAO domain-containing protein. (341 aa)
NOS2Nitric oxide synthase; Produces nitric oxide (NO). (1153 aa)
BCAT2Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (432 aa)
LOC114031842MR_MLE domain-containing protein. (443 aa)
PLOD2Fe2OG dioxygenase domain-containing protein. (758 aa)
HMGCLL1Pyruvate carboxyltransferase domain-containing protein. (339 aa)
AFMIDKynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites. (302 aa)
ENOPH1Enolase-phosphatase E1; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). (260 aa)
GOT1L1Aminotran_1_2 domain-containing protein. (411 aa)
CDO1Cysteine dioxygenase. (200 aa)
SHMT1Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (484 aa)
LOC114049648Uncharacterized protein. (1591 aa)
QRSL1Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). Belongs to the amidase family. GatA subfamily. (527 aa)
LOC114049892Uncharacterized protein. (1003 aa)
ADI11,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Also down-regulates cell migration mediated by MMP14. Belongs to the acireductone dioxygenase (ARD) family. (179 aa)
GLULGlutamine synthetase. (373 aa)
PIPOXPipecolic acid and sarcosine oxidase. (387 aa)
ABATUncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (500 aa)
IDO1Uncharacterized protein. (399 aa)
IDO2Uncharacterized protein. (419 aa)
DDAH1Uncharacterized protein. (285 aa)
GCLCUncharacterized protein. (637 aa)
BLMHBleomycin hydrolase; Belongs to the peptidase C1 family. (458 aa)
ENSVURP00010011731Uncharacterized protein. (269 aa)
LARS1Uncharacterized protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (1176 aa)
ETFBETF domain-containing protein. (255 aa)
AADATAminotran_1_2 domain-containing protein. (425 aa)
PYCR1Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family. (320 aa)
NAGSN-acetyltransferase domain-containing protein. (548 aa)
WARS2Uncharacterized protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (359 aa)
IVDUncharacterized protein. (422 aa)
ENSVURP00010010496D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (581 aa)
ENSVURP000100104632-Hacid_dh_C domain-containing protein. (125 aa)
THNSL2Uncharacterized protein. (481 aa)
SRRSerine racemase. (414 aa)
ADSSAdenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (456 aa)
HAO1FMN hydroxy acid dehydrogenase domain-containing protein. (370 aa)
PCBD2Uncharacterized protein. (138 aa)
NOS3Nitric oxide synthase; Produces nitric oxide (NO). (1193 aa)
ACMSD2-amino-3-carboxymuconate-6-semialdehyde decarboxylase; Converts alpha-amino-beta-carboxymuconate-epsilon- semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). Belongs to the metallo-dependent hydrolases superfamily. (336 aa)
LOC114049669Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract. (474 aa)
PARS2AA_TRNA_LIGASE_II domain-containing protein. (497 aa)
DAODAO domain-containing protein. (345 aa)
AZIN1Uncharacterized protein; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (447 aa)
TPH2Uncharacterized protein. (485 aa)
ENSVURP00010009072Iodothyronine deiodinase; Responsible for the deiodination of T4 (3,5,3',5'- tetraiodothyronine). (120 aa)
DARS1AA_TRNA_LIGASE_II domain-containing protein. (563 aa)
MTAPS-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. (283 aa)
GATCGlutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). Belongs to the GatC family. (156 aa)
SIRT4NAD-dependent protein lipoamidase sirtuin-4, mitochondrial; Acts as NAD-dependent protein lipoamidase, ADP-ribosyl transferase and deacetylase. Catalyzes more efficiently removal of lipoyl- and biotinyl- than acetyl-lysine modifications. Inhibits the pyruvate dehydrogenase complex (PDH) activity via the enzymatic hydrolysis of the lipoamide cofactor from the E2 component, DLAT, in a phosphorylation-independent manner. Catalyzes the transfer of ADP- ribosyl groups onto target proteins, including mitochondrial GLUD1, inhibiting GLUD1 enzyme activity. Acts as a negative regulator of mitoc [...] (352 aa)
GLDCGlycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. (1031 aa)
TPH1Uncharacterized protein. (444 aa)
GNMTGlycine N-methyltransferase. (295 aa)
RARS2Arginyl-tRNA synthetase 2, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family. (623 aa)
FAHFumarylacetoacetase. (419 aa)
ENSVURP00010007668annotation not available (1337 aa)
LOC114034219Glutamine amidotransferase type-1 domain-containing protein. (1337 aa)
NOX4FAD-binding FR-type domain-containing protein. (578 aa)
DARS2AA_TRNA_LIGASE_II domain-containing protein. (696 aa)
KYNUKynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. Has a preference for the L-3-hydroxy form. Also has cysteine-conjugate-beta-lyase activity. Belongs to the kynureninase family. (464 aa)
ASLUncharacterized protein. (464 aa)
ENSVURP00010007187Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1254 aa)
NOS1Nitric oxide synthase; Produces nitric oxide (NO). (1434 aa)
ENSVURP00010007029tRNA-synt_1e domain-containing protein. (574 aa)
ASPGAsparaginase. (531 aa)
PSPHUncharacterized protein. (225 aa)
TARS1AA_TRNA_LIGASE_II domain-containing protein. (722 aa)
ALDH4A1Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family. (562 aa)
BCKDHBTransket_pyr domain-containing protein. (394 aa)
SDSLPALP domain-containing protein. (331 aa)
SDSSerine dehydratase. (325 aa)
AARS2AA_TRNA_LIGASE_II_ALA domain-containing protein; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain. Belongs to the class-II aminoacyl-tRNA synthetase family. (990 aa)
Your Current Organism:
Vombatus ursinus
NCBI taxonomy Id: 29139
Other names: V. ursinus, coarse-haired wombat, common wombat
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