STRINGSTRING
FGFR4 FGFR4 FIBP FIBP INSR INSR ENSVURP00010000389 ENSVURP00010000389 RHBDF2 RHBDF2 API5 API5 IGFBPL1 IGFBPL1 EPHA2 EPHA2 LOC114031690 LOC114031690 ACVR2B ACVR2B EGFR EGFR NTRK1 NTRK1 WFIKKN2 WFIKKN2 SORT1 SORT1 ENSVURP00010019069 ENSVURP00010019069 LOC114025658 LOC114025658 WFIKKN1 WFIKKN1 LOC114045927 LOC114045927 LOC114045863 LOC114045863 LOC114049654 LOC114049654 ENSVURP00010020952 ENSVURP00010020952 ENSVURP00010020972 ENSVURP00010020972 ENG ENG ENSVURP00010021329 ENSVURP00010021329 TRIM16 TRIM16 ENSVURP00010021762 ENSVURP00010021762 ENSVURP00010021787 ENSVURP00010021787 TSKU TSKU LRRC32 LRRC32 ENSVURP00010022183 ENSVURP00010022183 GHRHR GHRHR LOC114049979 LOC114049979 LOC114051918 LOC114051918 FGFR2 FGFR2 COL3A1 COL3A1 ITGAV ITGAV ENSVURP00010023617 ENSVURP00010023617 LTBP2 LTBP2 LTBP1 LTBP1 ENSVURP00010024911 ENSVURP00010024911 ENSVURP00010025478 ENSVURP00010025478 FLT4 FLT4 LOC114025658-2 LOC114025658-2 ITGA6 ITGA6 FLT1 FLT1 LOC114054165-2 LOC114054165-2 FLT3 FLT3 IL1RN IL1RN IL36RN IL36RN IL6ST IL6ST FGFRL1 FGFRL1 FGFR3 FGFR3 NKD2 NKD2 ENSVURP00010028522 ENSVURP00010028522 LOC114045863-2 LOC114045863-2 ENSVURP00010029067 ENSVURP00010029067 LOC114049829 LOC114049829 ENSVURP00010029311 ENSVURP00010029311 TGFBR2 TGFBR2 ENSVURP00010029594 ENSVURP00010029594 ENSVURP00010029723 ENSVURP00010029723 ENSVURP00010029726 ENSVURP00010029726 GLG1 GLG1 EPHA8 EPHA8 LTBP4 LTBP4 NRP1 NRP1 ENSVURP00010031451 ENSVURP00010031451 COL1A2 COL1A2 IGFBP6 IGFBP6 IGFBP7 IGFBP7 IGFALS IGFALS CEP57 CEP57 LOC114028023 LOC114028023 KDR KDR PDGFRA PDGFRA FGFR1 FGFR1 CCN1 CCN1 PCSK6 PCSK6 IL2RA IL2RA IGF1R IGF1R THBS1 THBS1 SCN5A SCN5A PDGFRB PDGFRB COL1A1 COL1A1 NRROS NRROS NGFR NGFR ACVRL1 ACVRL1 LOC114054165 LOC114054165 COL2A1 COL2A1 ACVR2A ACVR2A IL10RA IL10RA IGFBP4 IGFBP4 IL2RB IL2RB PDGFB PDGFB KAZALD1 KAZALD1 GPC1 GPC1 IGFBP2 IGFBP2 IGFBP5 IGFBP5 LOC114043670 LOC114043670 LIFR LIFR OSMR OSMR LTBP3 LTBP3 LOC114025808 LOC114025808 ENSVURP00010002081 ENSVURP00010002081
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FGFR4Fibroblast growth factor receptor. (849 aa)
FIBPFGF1 intracellular binding protein. (368 aa)
INSRTyrosine-protein kinase receptor. (1374 aa)
ENSVURP00010000389Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1256 aa)
RHBDF2Rhomboid domain-containing protein. (830 aa)
API5Uncharacterized protein. (505 aa)
IGFBPL1Uncharacterized protein. (318 aa)
EPHA2Uncharacterized protein. (975 aa)
LOC114031690Uncharacterized protein. (222 aa)
ACVR2BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (511 aa)
EGFRReceptor protein-tyrosine kinase. (1214 aa)
NTRK1Tyrosine-protein kinase receptor. (743 aa)
WFIKKN2Uncharacterized protein. (567 aa)
SORT1Sortilin. (833 aa)
ENSVURP00010019069Uncharacterized protein. (949 aa)
LOC114025658Tyrosine-protein kinase receptor. (821 aa)
WFIKKN1Uncharacterized protein. (556 aa)
LOC114045927Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (511 aa)
LOC114045863Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (479 aa)
LOC114049654Uncharacterized protein. (466 aa)
ENSVURP00010020952HCLS1-associated protein X-1; Recruits the Arp2/3 complex to the cell cortex and regulates reorganization of the cortical actin cytoskeleton via its interaction with KCNC3 and the Arp2/3 complex. Slows down the rate of inactivation of KCNC3 channels. Promotes GNA13-mediated cell migration. Involved in the clathrin-mediated endocytosis pathway. May be involved in internalization of ABC transporters such as ABCB11. May inhibit CASP9 and CASP3. Promotes cell survival. May regulate intracellular calcium pools. (285 aa)
ENSVURP00010020972annotation not available (867 aa)
ENGZP domain-containing protein. (655 aa)
ENSVURP00010021329TGFb_propeptide domain-containing protein. (131 aa)
TRIM16Uncharacterized protein. (572 aa)
ENSVURP00010021762annotation not available (509 aa)
ENSVURP00010021787annotation not available (96 aa)
TSKUUncharacterized protein. (353 aa)
LRRC32Uncharacterized protein. (670 aa)
ENSVURP00010022183Uncharacterized protein. (271 aa)
GHRHRGrowth hormone releasing hormone receptor; Belongs to the G-protein coupled receptor 2 family. (448 aa)
LOC114049979S_100 domain-containing protein; Belongs to the S-100 family. (98 aa)
LOC114051918PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (211 aa)
FGFR2Fibroblast growth factor receptor. (840 aa)
COL3A1Uncharacterized protein. (1460 aa)
ITGAVIntegrin_alpha2 domain-containing protein; Belongs to the integrin alpha chain family. (1063 aa)
ENSVURP00010023617Fibronectin type-II domain-containing protein. (2422 aa)
LTBP2Latent transforming growth factor beta binding protein 2. (1715 aa)
LTBP1Uncharacterized protein. (1705 aa)
ENSVURP00010024911annotation not available (2422 aa)
ENSVURP00010025478annotation not available (211 aa)
FLT4Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1377 aa)
LOC114025658-2Tyrosine-protein kinase receptor. (824 aa)
ITGA6Integrin_alpha2 domain-containing protein; Belongs to the integrin alpha chain family. (1075 aa)
FLT1Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1341 aa)
LOC114054165-2Uncharacterized protein. (299 aa)
FLT3Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (999 aa)
IL1RNInterleukin-1. (175 aa)
IL36RNInterleukin-1. (153 aa)
IL6STUncharacterized protein. (921 aa)
FGFRL1Uncharacterized protein. (495 aa)
FGFR3Fibroblast growth factor receptor. (851 aa)
NKD2EF-hand domain-containing protein. (451 aa)
ENSVURP00010028522annotation not available (511 aa)
LOC114045863-2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (493 aa)
ENSVURP00010029067annotation not available (466 aa)
LOC114049829HCLS1-associated protein X-1; Recruits the Arp2/3 complex to the cell cortex and regulates reorganization of the cortical actin cytoskeleton via its interaction with KCNC3 and the Arp2/3 complex. Slows down the rate of inactivation of KCNC3 channels. Promotes GNA13-mediated cell migration. Involved in the clathrin-mediated endocytosis pathway. May be involved in internalization of ABC transporters such as ABCB11. May inhibit CASP9 and CASP3. Promotes cell survival. May regulate intracellular calcium pools. (276 aa)
ENSVURP00010029311annotation not available (222 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (565 aa)
ENSVURP00010029594annotation not available (98 aa)
ENSVURP00010029723TGF_BETA_2 domain-containing protein. (264 aa)
ENSVURP00010029726annotation not available (264 aa)
GLG1Uncharacterized protein. (1183 aa)
EPHA8EPH receptor A8. (970 aa)
LTBP4Uncharacterized protein. (1585 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (922 aa)
ENSVURP00010031451Uncharacterized protein. (917 aa)
COL1A2Fibrillar collagen NC1 domain-containing protein. (1336 aa)
IGFBP6Uncharacterized protein. (235 aa)
IGFBP7Uncharacterized protein. (287 aa)
IGFALSLRRNT domain-containing protein. (609 aa)
CEP57Uncharacterized protein. (494 aa)
LOC114028023Uncharacterized protein. (401 aa)
KDRUncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1349 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1086 aa)
FGFR1Fibroblast growth factor receptor. (822 aa)
CCN1Uncharacterized protein. (382 aa)
PCSK6Uncharacterized protein; Belongs to the peptidase S8 family. (911 aa)
IL2RAUncharacterized protein. (300 aa)
IGF1RTyrosine-protein kinase receptor. (1362 aa)
THBS1Uncharacterized protein. (1172 aa)
SCN5ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2029 aa)
PDGFRBUncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1101 aa)
COL1A1Uncharacterized protein. (1453 aa)
NRROSUncharacterized protein. (691 aa)
NGFRNerve growth factor receptor. (428 aa)
ACVRL1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (501 aa)
LOC114054165Uncharacterized protein. (303 aa)
COL2A1Uncharacterized protein. (1490 aa)
ACVR2ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (513 aa)
IL10RAFibronectin type-III domain-containing protein. (619 aa)
IGFBP4Uncharacterized protein. (260 aa)
IL2RBFibronectin type-III domain-containing protein. (561 aa)
PDGFBPDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (239 aa)
KAZALD1Kazal type serine peptidase inhibitor domain 1. (302 aa)
GPC1Uncharacterized protein; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (556 aa)
IGFBP2Uncharacterized protein. (318 aa)
IGFBP5Uncharacterized protein. (271 aa)
LOC114043670Rhomboid domain-containing protein. (867 aa)
LIFRUncharacterized protein. (1100 aa)
OSMRUncharacterized protein. (969 aa)
LTBP3Uncharacterized protein. (1287 aa)
LOC114025808Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum. (96 aa)
ENSVURP00010002081Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
Your Current Organism:
Vombatus ursinus
NCBI taxonomy Id: 29139
Other names: V. ursinus, coarse-haired wombat, common wombat
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