35 items (Vombatus ursinus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	BCL10	CARD domain-containing protein. (238 aa)
	ENSVURP00010006368	BPI2 domain-containing protein. (367 aa)
	ENSVURP00010006358	Uncharacterized protein. (81 aa)
	LOC114047389	TIR domain-containing protein; Belongs to the Toll-like receptor family. (832 aa)
	MALT1	Uncharacterized protein. (820 aa)
	CD6	Uncharacterized protein. (633 aa)
	TGFB1	Transforming growth factor beta; Belongs to the TGF-beta family. (382 aa)
	LOC114047064	Uncharacterized protein. (469 aa)
	TNF	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (232 aa)
	ENSVURP00010031546	CARD domain-containing protein. (217 aa)
	MAPK1	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (349 aa)
	ENSVURP00010027896	annotation not available (155 aa)
	IRAK1	Protein kinase domain-containing protein. (727 aa)
	NFKBIA	ANK_REP_REGION domain-containing protein. (321 aa)
	ENSVURP00010026522	annotation not available (514 aa)
	CD180	LRRCT domain-containing protein. (664 aa)
	IL18	Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (198 aa)
	LOC114032095	Uncharacterized protein. (208 aa)
	CD14	Uncharacterized protein. (382 aa)
	LOC114053699	ML domain-containing protein. (163 aa)
	LOC114039188	C-C motif chemokine. (91 aa)
	PLCG2	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1264 aa)
	LOC114047389-2	TIR domain-containing protein; Belongs to the Toll-like receptor family. (881 aa)
	LOC114047064-2	Uncharacterized protein. (493 aa)
	IRF3	IRF tryptophan pentad repeat domain-containing protein. (412 aa)
	LOC114046725	Uncharacterized protein. (482 aa)
	ENSVURP00010016345	annotation not available (379 aa)
	ENSVURP00010016304	Uncharacterized protein; Belongs to the CD36 family. (379 aa)
	MYD88	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (318 aa)
	IRAK2	Uncharacterized protein. (649 aa)
	IL1B	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (299 aa)
	MAPK3	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
	MTDH	Uncharacterized protein. (635 aa)
	LOC114053900	Tyrosine-protein kinase. (514 aa)
	RIPK2	Uncharacterized protein. (540 aa)

Your Current Organism:

Vombatus ursinus

NCBI taxonomy Id: 29139
Other names: V. ursinus, coarse-haired wombat, common wombat

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BCL10	LOC114047389	ENSVURP00010012762	ENSVURP00010005912	CARD domain-containing protein.	TIR domain-containing protein; Belongs to the Toll-like receptor family.	0.418
BCL10	LOC114047389-2	ENSVURP00010012762	ENSVURP00010020176	CARD domain-containing protein.	TIR domain-containing protein; Belongs to the Toll-like receptor family.	0.418
BCL10	MALT1	ENSVURP00010012762	ENSVURP00010005393	CARD domain-containing protein.	Uncharacterized protein.	0.993
BCL10	MAPK1	ENSVURP00010012762	ENSVURP00010028502	CARD domain-containing protein.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.737
BCL10	MAPK3	ENSVURP00010012762	ENSVURP00010011204	CARD domain-containing protein.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.737
BCL10	NFKBIA	ENSVURP00010012762	ENSVURP00010026714	CARD domain-containing protein.	ANK_REP_REGION domain-containing protein.	0.767
BCL10	RIPK2	ENSVURP00010012762	ENSVURP00010006905	CARD domain-containing protein.	Uncharacterized protein.	0.652
CD14	CD180	ENSVURP00010022683	ENSVURP00010025530	Uncharacterized protein.	LRRCT domain-containing protein.	0.714
CD14	ENSVURP00010006358	ENSVURP00010022683	ENSVURP00010006358	Uncharacterized protein.	Uncharacterized protein.	0.674
CD14	ENSVURP00010006368	ENSVURP00010022683	ENSVURP00010006368	Uncharacterized protein.	BPI2 domain-containing protein.	0.674
CD14	ENSVURP00010027896	ENSVURP00010022683	ENSVURP00010027896	Uncharacterized protein.	annotation not available	0.868
CD14	IRAK2	ENSVURP00010022683	ENSVURP00010015066	Uncharacterized protein.	Uncharacterized protein.	0.568
CD14	IRF3	ENSVURP00010022683	ENSVURP00010017835	Uncharacterized protein.	IRF tryptophan pentad repeat domain-containing protein.	0.623
CD14	LOC114046725	ENSVURP00010022683	ENSVURP00010017392	Uncharacterized protein.	Uncharacterized protein.	0.882
CD14	LOC114047064	ENSVURP00010022683	ENSVURP00010002655	Uncharacterized protein.	Uncharacterized protein.	0.761
CD14	LOC114047064-2	ENSVURP00010022683	ENSVURP00010018392	Uncharacterized protein.	Uncharacterized protein.	0.761
CD14	LOC114047389	ENSVURP00010022683	ENSVURP00010005912	Uncharacterized protein.	TIR domain-containing protein; Belongs to the Toll-like receptor family.	0.934
CD14	LOC114047389-2	ENSVURP00010022683	ENSVURP00010020176	Uncharacterized protein.	TIR domain-containing protein; Belongs to the Toll-like receptor family.	0.934
CD14	LOC114053699	ENSVURP00010022683	ENSVURP00010021989	Uncharacterized protein.	ML domain-containing protein.	0.868
CD14	PLCG2	ENSVURP00010022683	ENSVURP00010021372	Uncharacterized protein.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.727