(27 nodes) Regulation of mast cell activation involved in immune response network (Vombatus ursinus)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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Predicted Interactions

gene neighborhood

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Your Input:
	GAB2	PH domain-containing protein. (682 aa)
	PTPN6	Protein tyrosine phosphatase non-receptor type 6. (578 aa)
	LOC114043698	Protein kinase domain-containing protein. (683 aa)
	RABGEF1	Uncharacterized protein. (491 aa)
	IL13	Uncharacterized protein. (145 aa)
	ENSVURP00010007674	Longin domain-containing protein. (71 aa)
	FER	Tyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (824 aa)
	LOC114053900	Tyrosine-protein kinase. (514 aa)
	FES	Tyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa)
	SYK	Uncharacterized protein. (639 aa)
	ENSVURP00010009055	Uncharacterized protein. (171 aa)
	IL4R	Fibronectin type-III domain-containing protein. (933 aa)
	LOC114044833	Tyrosine-protein kinase. (531 aa)
	C12orf4	Uncharacterized protein. (561 aa)
	BLK	Tyrosine-protein kinase. (502 aa)
	VAMP8	V-SNARE coiled-coil homology domain-containing protein. (99 aa)
	ENSVURP00010013594	Uncharacterized protein. (326 aa)
	SPHK2	DAGKc domain-containing protein. (732 aa)
	ENSVURP00010014699	Uncharacterized protein. (587 aa)
	UNC13D	Uncharacterized protein. (1088 aa)
	ENSVURP00010018054	Ig-like domain-containing protein. (387 aa)
	ENSVURP00010021023	annotation not available (683 aa)
	GATA2	Uncharacterized protein. (473 aa)
	ENSVURP00010024717	Tyrosine-protein kinase. (479 aa)
	ENSVURP00010025482	Uncharacterized protein. (177 aa)
	ENSVURP00010026522	annotation not available (514 aa)
	VAMP7	Uncharacterized protein; Belongs to the synaptobrevin family. (234 aa)

Your Current Organism:

Vombatus ursinus

NCBI taxonomy Id: 29139
Other names: V. ursinus, coarse-haired wombat, common wombat

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BLK	ENSVURP00010021023	ENSVURP00010010244	ENSVURP00010021023	Tyrosine-protein kinase.	annotation not available	0.534
BLK	FER	ENSVURP00010010244	ENSVURP00010007810	Tyrosine-protein kinase.	Tyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily.	0.705
BLK	FES	ENSVURP00010010244	ENSVURP00010008619	Tyrosine-protein kinase.	Tyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily.	0.719
BLK	GAB2	ENSVURP00010010244	ENSVURP00010021599	Tyrosine-protein kinase.	PH domain-containing protein.	0.663
BLK	LOC114043698	ENSVURP00010010244	ENSVURP00010002963	Tyrosine-protein kinase.	Protein kinase domain-containing protein.	0.534
BLK	PTPN6	ENSVURP00010010244	ENSVURP00010002534	Tyrosine-protein kinase.	Protein tyrosine phosphatase non-receptor type 6.	0.642
BLK	SYK	ENSVURP00010010244	ENSVURP00010008906	Tyrosine-protein kinase.	Uncharacterized protein.	0.742
ENSVURP00010007674	ENSVURP00010009055	ENSVURP00010007674	ENSVURP00010009055	Longin domain-containing protein.	Uncharacterized protein.	0.585
ENSVURP00010007674	ENSVURP00010025482	ENSVURP00010007674	ENSVURP00010025482	Longin domain-containing protein.	Uncharacterized protein.	0.585
ENSVURP00010007674	RABGEF1	ENSVURP00010007674	ENSVURP00010007453	Longin domain-containing protein.	Uncharacterized protein.	0.640
ENSVURP00010007674	VAMP8	ENSVURP00010007674	ENSVURP00010011916	Longin domain-containing protein.	V-SNARE coiled-coil homology domain-containing protein.	0.910
ENSVURP00010009055	ENSVURP00010007674	ENSVURP00010009055	ENSVURP00010007674	Uncharacterized protein.	Longin domain-containing protein.	0.585
ENSVURP00010009055	VAMP7	ENSVURP00010009055	ENSVURP00010027558	Uncharacterized protein.	Uncharacterized protein; Belongs to the synaptobrevin family.	0.585
ENSVURP00010009055	VAMP8	ENSVURP00010009055	ENSVURP00010011916	Uncharacterized protein.	V-SNARE coiled-coil homology domain-containing protein.	0.578
ENSVURP00010013594	GATA2	ENSVURP00010013594	ENSVURP00010021628	Uncharacterized protein.	Uncharacterized protein.	0.760
ENSVURP00010018054	PTPN6	ENSVURP00010018054	ENSVURP00010002534	Ig-like domain-containing protein.	Protein tyrosine phosphatase non-receptor type 6.	0.623
ENSVURP00010021023	BLK	ENSVURP00010021023	ENSVURP00010010244	annotation not available	Tyrosine-protein kinase.	0.534
ENSVURP00010021023	ENSVURP00010024717	ENSVURP00010021023	ENSVURP00010024717	annotation not available	Tyrosine-protein kinase.	0.559
ENSVURP00010021023	ENSVURP00010026522	ENSVURP00010021023	ENSVURP00010026522	annotation not available	annotation not available	0.566
ENSVURP00010021023	FER	ENSVURP00010021023	ENSVURP00010007810	annotation not available	Tyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily.	0.478