STRINGSTRING
LOC114030666-2 LOC114030666-2 GLI3 GLI3 SOX13 SOX13 EFNB1 EFNB1 ABL1 ABL1 VSIR VSIR DHPS DHPS CD81 CD81 ENSVURP00010015540 ENSVURP00010015540 IGF2 IGF2 ENSVURP00010015338 ENSVURP00010015338 TRAF6 TRAF6 RAG1 RAG1 LOC114030666 LOC114030666 LOC114040819 LOC114040819 LOC114040884 LOC114040884 ADAM8 ADAM8 ENSVURP00010013836 ENSVURP00010013836 MDK MDK AMBRA1 AMBRA1 ENSVURP00010013239 ENSVURP00010013239 FLOT2 FLOT2 XBP1 XBP1 IL15 IL15 BCL10 BCL10 LOC114050197 LOC114050197 ENSVURP00010012358 ENSVURP00010012358 TNFSF11 TNFSF11 SHH SHH LOC114049588 LOC114049588 ENSVURP00010011377 ENSVURP00010011377 IL1B IL1B NCK1 NCK1 CORO1A CORO1A RASGRP1 RASGRP1 ABL2 ABL2 TESPA1 TESPA1 VTCN1 VTCN1 NCKAP1L NCKAP1L ENSVURP00010010444 ENSVURP00010010444 LOC114025005 LOC114025005 RHOH RHOH TFRC TFRC CD74 CD74 DOCK8 DOCK8 ENSVURP00010009759 ENSVURP00010009759 LOC114027088 LOC114027088 IL4R IL4R SYK SYK JAK2 JAK2 CD274 CD274 ENSVURP00010008605 ENSVURP00010008605 WNT10B WNT10B ENSVURP00010008007 ENSVURP00010008007 LOC114053378 LOC114053378 ENSVURP00010007928 ENSVURP00010007928 LOC114053528 LOC114053528 HLA-DRA HLA-DRA ENSVURP00010007328 ENSVURP00010007328 ENSVURP00010007254 ENSVURP00010007254 ENSVURP00010007145 ENSVURP00010007145 CD28 CD28 ICOS ICOS AGER AGER RIPK2 RIPK2 ENSVURP00010006612 ENSVURP00010006612 CCR7 CCR7 BAD BAD ENSVURP00010006200 ENSVURP00010006200 ENSVURP00010006162 ENSVURP00010006162 CCDC88B CCDC88B PTPRC PTPRC LOC114046290 LOC114046290 LOC114046303 LOC114046303 MALT1 MALT1 MYB MYB LEF1 LEF1 ENSVURP00010004917 ENSVURP00010004917 LEP LEP THY1 THY1 CD6 CD6 CD5 CD5 TGFB1 TGFB1 ZP3 ZP3 LOC114047099 LOC114047099 NLRP12 NLRP12 ENSVURP00010003617 ENSVURP00010003617 ENSVURP00010003614 ENSVURP00010003614 SPTA1 SPTA1 CD83 CD83 IGFBP2 IGFBP2 LOC114033910 LOC114033910 ENSVURP00010000041 ENSVURP00010000041 ENSVURP00010000767 ENSVURP00010000767 LOC114043367 LOC114043367 SASH3 SASH3 SART1 SART1 SOX4 SOX4 KAT5 KAT5 IHH IHH ADA ADA AIF1 AIF1 ENSVURP00010002618 ENSVURP00010002618 LOC114050566 LOC114050566 ENSVURP00010002791 ENSVURP00010002791 LOC114046276 LOC114046276 EFNB3 EFNB3 ENSVURP00010031879 ENSVURP00010031879 TNFSF14 TNFSF14 ENSVURP00010031693 ENSVURP00010031693 IFNG IFNG ENSVURP00010031546 ENSVURP00010031546 IGF1 IGF1 IL23A IL23A NFKBID NFKBID ZBTB1 ZBTB1 BCL6 BCL6 BMI1 BMI1 ENSVURP00010029866 ENSVURP00010029866 ENSVURP00010029861 ENSVURP00010029861 EPHB6 EPHB6 ENSVURP00010029680 ENSVURP00010029680 ENSVURP00010029673 ENSVURP00010029673 TGFBR2 TGFBR2 ENSVURP00010029447 ENSVURP00010029447 ENSVURP00010029419 ENSVURP00010029419 ENSVURP00010029376 ENSVURP00010029376 ENSVURP00010029349 ENSVURP00010029349 ENSVURP00010028996 ENSVURP00010028996 ENSVURP00010028887 ENSVURP00010028887 ENSVURP00010028631 ENSVURP00010028631 ENSVURP00010028558 ENSVURP00010028558 CBFB CBFB DPP4 DPP4 IL6ST IL6ST FOXP3 FOXP3 LOC114030820 LOC114030820 SLC7A1 SLC7A1 ENSVURP00010026384 ENSVURP00010026384 ENSVURP00010026284 ENSVURP00010026284 CAV1 CAV1 ENSVURP00010025709 ENSVURP00010025709 IL18 IL18 LOC114032095 LOC114032095 AP3B1 AP3B1 CARD11 CARD11 ZBTB16 ZBTB16 PCK1 PCK1 CD27 CD27 ENSVURP00010023734 ENSVURP00010023734 RPS3 RPS3 HSPD1 HSPD1 ENSVURP00010022058 ENSVURP00010022058 IL12A IL12A LOC114048474 LOC114048474 CD40LG CD40LG ENSVURP00010021437 ENSVURP00010021437 ENSVURP00010021050 ENSVURP00010021050 ANXA1 ANXA1 ENSVURP00010020805 ENSVURP00010020805 LOC114049705 LOC114049705 SOCS5 SOCS5 CCL19 CCL19 LOC114052665 LOC114052665 PRKCQ PRKCQ EGR3 EGR3 IL7R IL7R HLA-DMA HLA-DMA ENSVURP00010019467 ENSVURP00010019467 ENSVURP00010019380 ENSVURP00010019380 JAK3 JAK3 IL21 IL21 IL2 IL2 GATA3 GATA3 ENSVURP00010018786 ENSVURP00010018786 ZMIZ1 ZMIZ1 ENSVURP00010018483 ENSVURP00010018483 ENSVURP00010018452 ENSVURP00010018452 IL12RB2 IL12RB2 ENSVURP00010018107 ENSVURP00010018107 ENSVURP00010018047 ENSVURP00010018047 NFKBIZ NFKBIZ GPAM GPAM RASAL3 RASAL3 ZAP70 ZAP70 TMIGD2 TMIGD2 FADD FADD
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC114030666-2Uncharacterized protein. (400 aa)
GLI3Uncharacterized protein. (1584 aa)
SOX13SRY-box 13. (603 aa)
EFNB1Ephrin B1; Belongs to the ephrin family. (443 aa)
ABL1Tyrosine-protein kinase. (1148 aa)
VSIRIg-like domain-containing protein. (348 aa)
DHPSUncharacterized protein. (377 aa)
CD81Uncharacterized protein; Belongs to the tetraspanin (TM4SF) family. (299 aa)
ENSVURP00010015540Ig-like domain-containing protein. (359 aa)
IGF2IlGF domain-containing protein. (226 aa)
ENSVURP00010015338SH2 domain-containing protein. (485 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (540 aa)
RAG1V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...] (1047 aa)
LOC114030666Uncharacterized protein. (324 aa)
LOC114040819Uncharacterized protein. (200 aa)
LOC114040884Uncharacterized protein. (196 aa)
ADAM8Uncharacterized protein. (842 aa)
ENSVURP00010013836A_deaminase domain-containing protein. (249 aa)
MDKUncharacterized protein. (142 aa)
AMBRA1WD_REPEATS_REGION domain-containing protein. (1192 aa)
ENSVURP00010013239Uncharacterized protein. (81 aa)
FLOT2Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (428 aa)
XBP1X-box binding protein 1. (266 aa)
IL15Interleukin; Belongs to the IL-15/IL-21 family. (183 aa)
BCL10CARD domain-containing protein. (238 aa)
LOC114050197Uncharacterized protein. (482 aa)
ENSVURP00010012358KH type-2 domain-containing protein. (144 aa)
TNFSF11Tumor necrosis factor ligand superfamily member. (314 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (467 aa)
LOC114049588Kinase; Belongs to the inositol phosphokinase (IPK) family. (977 aa)
ENSVURP00010011377Interleukin-1. (135 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (299 aa)
NCK1Cytoplasmic protein. (377 aa)
CORO1ACoronin; Belongs to the WD repeat coronin family. (461 aa)
RASGRP1RAS guanyl releasing protein 1. (761 aa)
ABL2Tyrosine-protein kinase. (1143 aa)
TESPA1KRAP_IP3R_bind domain-containing protein. (611 aa)
VTCN1Uncharacterized protein. (324 aa)
NCKAP1LUncharacterized protein. (1134 aa)
ENSVURP00010010444Ig-like domain-containing protein. (244 aa)
LOC114025005Ig-like domain-containing protein. (266 aa)
RHOHUncharacterized protein. (191 aa)
TFRCUncharacterized protein. (770 aa)
CD74Thyroglobulin type-1 domain-containing protein. (275 aa)
DOCK8Uncharacterized protein; Belongs to the DOCK family. (2102 aa)
ENSVURP00010009759annotation not available (380 aa)
LOC114027088AIG1-type G domain-containing protein. (320 aa)
IL4RFibronectin type-III domain-containing protein. (933 aa)
SYKUncharacterized protein. (639 aa)
JAK2Tyrosine-protein kinase. (1132 aa)
CD274Ig-like domain-containing protein. (272 aa)
ENSVURP00010008605Ig-like domain-containing protein. (257 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
ENSVURP00010008007Ig-like domain-containing protein. (157 aa)
LOC114053378Ig-like domain-containing protein; Belongs to the MHC class II family. (256 aa)
ENSVURP00010007928KH type-2 domain-containing protein. (161 aa)
LOC114053528Ig-like domain-containing protein. (264 aa)
HLA-DRAIg-like domain-containing protein; Belongs to the MHC class II family. (256 aa)
ENSVURP00010007328Uncharacterized protein. (312 aa)
ENSVURP00010007254Uncharacterized protein. (183 aa)
ENSVURP00010007145Uncharacterized protein. (277 aa)
CD28IGv domain-containing protein. (221 aa)
ICOSIGv domain-containing protein. (203 aa)
AGERUncharacterized protein. (412 aa)
RIPK2Uncharacterized protein. (540 aa)
ENSVURP00010006612Uncharacterized protein. (151 aa)
CCR7G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (374 aa)
BADUncharacterized protein. (180 aa)
ENSVURP00010006200Ig-like domain-containing protein. (259 aa)
ENSVURP00010006162KH type-2 domain-containing protein. (90 aa)
CCDC88BUncharacterized protein. (1487 aa)
PTPRCUncharacterized protein. (1300 aa)
LOC114046290TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (298 aa)
LOC114046303Ephrin RBD domain-containing protein; Belongs to the ephrin family. (333 aa)
MALT1Uncharacterized protein. (820 aa)
MYBUncharacterized protein. (760 aa)
LEF1HMG box domain-containing protein. (417 aa)
ENSVURP00010004917Galectin. (136 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
THY1Ig-like domain-containing protein. (162 aa)
CD6Uncharacterized protein. (633 aa)
CD5SRCR domain-containing protein. (478 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (382 aa)
ZP3ZP domain-containing protein. (419 aa)
LOC114047099Uncharacterized protein. (406 aa)
NLRP12Uncharacterized protein. (1071 aa)
ENSVURP00010003617Uncharacterized protein. (149 aa)
ENSVURP00010003614Uncharacterized protein. (685 aa)
SPTA1Uncharacterized protein. (2408 aa)
CD83Ig-like domain-containing protein. (214 aa)
IGFBP2Uncharacterized protein. (318 aa)
LOC114033910Fibronectin type-III domain-containing protein. (455 aa)
ENSVURP00010000041Ig-like domain-containing protein. (139 aa)
ENSVURP00010000767Uncharacterized protein. (629 aa)
LOC114043367Ig-like domain-containing protein. (190 aa)
SASH3Uncharacterized protein. (394 aa)
SART1Spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP. (805 aa)
SOX4Transcription factor SOX. (436 aa)
KAT5Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (513 aa)
IHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (410 aa)
ADAA_deaminase domain-containing protein. (362 aa)
AIF1EF-hand domain-containing protein. (147 aa)
ENSVURP00010002618annotation not available (190 aa)
LOC114050566Uncharacterized protein. (215 aa)
ENSVURP00010002791Transcription factor SOX. (312 aa)
LOC114046276Cytoplasmic protein. (380 aa)
EFNB3Ephrin RBD domain-containing protein; Belongs to the ephrin family. (341 aa)
ENSVURP00010031879TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (305 aa)
TNFSF14TNF_2 domain-containing protein. (240 aa)
ENSVURP00010031693Uncharacterized protein. (365 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (164 aa)
ENSVURP00010031546CARD domain-containing protein. (217 aa)
IGF1Insulin like growth factor 1. (229 aa)
IL23AInterleukin 23 subunit alpha. (188 aa)
NFKBIDNFKB inhibitor delta. (383 aa)
ZBTB1Zinc finger and BTB domain containing 1. (644 aa)
BCL6Uncharacterized protein. (737 aa)
BMI1RING-type domain-containing protein. (327 aa)
ENSVURP00010029866Homeobox domain-containing protein. (481 aa)
ENSVURP00010029861Homeobox domain-containing protein. (474 aa)
EPHB6Uncharacterized protein. (1007 aa)
ENSVURP00010029680annotation not available (246 aa)
ENSVURP00010029673C2-set_2 domain-containing protein. (246 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (565 aa)
ENSVURP00010029447Tyrosine-protein kinase. (1149 aa)
ENSVURP00010029419Tyrosine-protein kinase. (1180 aa)
ENSVURP00010029376annotation not available (298 aa)
ENSVURP00010029349annotation not available (333 aa)
ENSVURP00010028996Uncharacterized protein. (517 aa)
ENSVURP00010028887Uncharacterized protein. (1013 aa)
ENSVURP00010028631SH2 domain-containing protein. (602 aa)
ENSVURP00010028558SH2 domain-containing protein. (618 aa)
CBFBUncharacterized protein. (182 aa)
DPP4Dipeptidyl peptidase 4; Belongs to the peptidase S9B family. (699 aa)
IL6STUncharacterized protein. (921 aa)
FOXP3Fork-head domain-containing protein. (452 aa)
LOC114030820Interleukin-1. (163 aa)
SLC7A1AA_permease_C domain-containing protein. (624 aa)
ENSVURP00010026384annotation not available (215 aa)
ENSVURP00010026284Uncharacterized protein. (330 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
ENSVURP00010025709MHC_II_beta domain-containing protein. (197 aa)
IL18Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (198 aa)
LOC114032095Uncharacterized protein. (208 aa)
AP3B1AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (1086 aa)
CARD11Uncharacterized protein. (1151 aa)
ZBTB16Uncharacterized protein. (562 aa)
PCK1Uncharacterized protein. (622 aa)
CD27TNFR-Cys domain-containing protein. (264 aa)
ENSVURP00010023734KH type-2 domain-containing protein. (123 aa)
RPS3KH type-2 domain-containing protein; Belongs to the universal ribosomal protein uS3 family. (243 aa)
HSPD1Uncharacterized protein; Belongs to the chaperonin (HSP60) family. (573 aa)
ENSVURP00010022058annotation not available (482 aa)
IL12AInterleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (215 aa)
LOC114048474Uncharacterized protein. (502 aa)
CD40LGCD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching. (253 aa)
ENSVURP00010021437Amine oxidase. (527 aa)
ENSVURP00010021050annotation not available (977 aa)
ANXA1Annexin. (346 aa)
ENSVURP00010020805Ig-like domain-containing protein. (158 aa)
LOC114049705Uncharacterized protein. (528 aa)
SOCS5Uncharacterized protein. (539 aa)
CCL19C-C motif chemokine. (101 aa)
LOC114052665Uncharacterized protein. (284 aa)
PRKCQProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (686 aa)
EGR3Uncharacterized protein. (386 aa)
IL7RFibronectin type-III domain-containing protein. (455 aa)
HLA-DMAIg-like domain-containing protein. (265 aa)
ENSVURP00010019467Uncharacterized protein. (274 aa)
ENSVURP00010019380annotation not available (406 aa)
JAK3Tyrosine-protein kinase. (1110 aa)
IL21Interleukin; Belongs to the IL-15/IL-21 family. (154 aa)
IL2Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (141 aa)
GATA3Uncharacterized protein. (444 aa)
ENSVURP00010018786A_deaminase domain-containing protein. (85 aa)
ZMIZ1SP-RING-type domain-containing protein. (1081 aa)
ENSVURP00010018483annotation not available (312 aa)
ENSVURP00010018452Uncharacterized protein. (634 aa)
IL12RB2Uncharacterized protein. (865 aa)
ENSVURP00010018107ZP domain-containing protein. (401 aa)
ENSVURP00010018047Uncharacterized protein. (404 aa)
NFKBIZANK_REP_REGION domain-containing protein. (725 aa)
GPAMGlycerol-3-phosphate acyltransferase 1, mitochondrial. (830 aa)
RASAL3Ras-GAP domain-containing protein. (1003 aa)
ZAP70Tyrosine-protein kinase. (617 aa)
TMIGD2Ig-like domain-containing protein. (248 aa)
FADDUncharacterized protein. (193 aa)
Your Current Organism:
Vombatus ursinus
NCBI taxonomy Id: 29139
Other names: V. ursinus, coarse-haired wombat, common wombat
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