STRINGSTRING
NODAL NODAL CELSR1 CELSR1 TGFBR2 TGFBR2 MAPK1 MAPK1 CTNNB1 CTNNB1 ENSVURP00010027854 ENSVURP00010027854 LIF LIF NOG NOG HHIP HHIP MAPK3 MAPK3 WNT2B WNT2B CTSH CTSH SRF SRF SEC24B SEC24B TCF21 TCF21 STK40 STK40 PLOD3 PLOD3 LOC114050299 LOC114050299 ESRP2 ESRP2 FOXA1 FOXA1 WNT2 WNT2 ENSVURP00010025716 ENSVURP00010025716 AP3B1 AP3B1 CTSZ CTSZ DAG1 DAG1 LOC114053908 LOC114053908 SPRY1 SPRY1 DLG5 DLG5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NODALNodal growth differentiation factor. (310 aa)
CELSR1Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (2748 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (565 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (349 aa)
CTNNB1Catenin beta 1. (744 aa)
ENSVURP00010027854annotation not available (341 aa)
LIFUncharacterized protein. (202 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
HHIPEGF-like domain-containing protein. (702 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
WNT2BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (398 aa)
CTSHPept_C1 domain-containing protein; Belongs to the peptidase C1 family. (251 aa)
SRFMADS-box domain-containing protein. (508 aa)
SEC24BSEC24 homolog B, COPII coat complex component. (1226 aa)
TCF21BHLH domain-containing protein. (179 aa)
STK40Protein kinase domain-containing protein. (435 aa)
PLOD3Fe2OG dioxygenase domain-containing protein. (768 aa)
LOC114050299Homeobox domain-containing protein. (269 aa)
ESRP2RRM domain-containing protein. (748 aa)
FOXA1Forkhead box A1. (470 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
ENSVURP00010025716annotation not available (269 aa)
AP3B1AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (1086 aa)
CTSZPept_C1 domain-containing protein; Belongs to the peptidase C1 family. (303 aa)
DAG1Peptidase S72 domain-containing protein. (895 aa)
LOC114053908Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (341 aa)
SPRY1Uncharacterized protein. (319 aa)
DLG5Uncharacterized protein; Belongs to the MAGUK family. (2030 aa)
Your Current Organism:
Vombatus ursinus
NCBI taxonomy Id: 29139
Other names: V. ursinus, coarse-haired wombat, common wombat
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