STRINGSTRING
ENSVURP00010029447 ENSVURP00010029447 SASH3 SASH3 IL34 IL34 GLMN GLMN OCSTAMP OCSTAMP PAWR PAWR IHH IHH ADA ADA BST1 BST1 SOS1 SOS1 LOC114050496 LOC114050496 AIF1 AIF1 PTPN6 PTPN6 SDC4 SDC4 LOC114050566 LOC114050566 ST6GAL1 ST6GAL1 BTK BTK CRTAM CRTAM IGFBP2 IGFBP2 NMBR NMBR SPTA1 SPTA1 ENSVURP00010003617 ENSVURP00010003617 ZP3 ZP3 TGFB1 TGFB1 CD6 CD6 ENSVURP00010004342 ENSVURP00010004342 ENSVURP00010004384 ENSVURP00010004384 LOC114046276 LOC114046276 LEP LEP MARCH7 MARCH7 PTH PTH VSIG4 VSIG4 TNFRSF21 TNFRSF21 CSF2RB CSF2RB LOC114046290 LOC114046290 PTPRC PTPRC CCDC88B CCDC88B ENSVURP00010006162 ENSVURP00010006162 ENSVURP00010006200 ENSVURP00010006200 RIPK2 RIPK2 AGER AGER CTLA4 CTLA4 CD28 CD28 ENSVURP00010007254 ENSVURP00010007254 ENSVURP00010007328 ENSVURP00010007328 IKZF3 IKZF3 RC3H1 RC3H1 IRF1 IRF1 ENSVURP00010007928 ENSVURP00010007928 LOC114053900 LOC114053900 CD274 CD274 JAK2 JAK2 SYK SYK ENSVURP00010009759 ENSVURP00010009759 CD74 CD74 TFRC TFRC BLK BLK LOC114025005 LOC114025005 CSF1R CSF1R NCKAP1L NCKAP1L VTCN1 VTCN1 ENSVURP00010010956 ENSVURP00010010956 CORO1A CORO1A NCK1 NCK1 IL20RB IL20RB ENSVURP00010011128 ENSVURP00010011128 MAPK3 MAPK3 IL1B IL1B GREM1 GREM1 SH3RF1 SH3RF1 NDFIP1 NDFIP1 SHH SHH LGALS3 LGALS3 SOS2 SOS2 LRRC1 LRRC1 ENSVURP00010012358 ENSVURP00010012358 IDO1 IDO1 IL15 IL15 ENSVURP00010013239 ENSVURP00010013239 KIT KIT ENSVURP00010013836 ENSVURP00010013836 ENSVURP00010014207 ENSVURP00010014207 LOC114042866 LOC114042866 FOXJ1 FOXJ1 MAPK8IP1 MAPK8IP1 NF1 NF1 LOC114040884 LOC114040884 LOC114040819 LOC114040819 ENSVURP00010015264 ENSVURP00010015264 TRAF6 TRAF6 MYD88 MYD88 IGF2 IGF2 ENSVURP00010015540 ENSVURP00010015540 PRNP PRNP TSPAN32 TSPAN32 CD81 CD81 TMEM131L TMEM131L IL10 IL10 DHPS DHPS RASSF5 RASSF5 VSIR VSIR EFNB1 EFNB1 BCL2 BCL2 PELI1 PELI1 CSF1 CSF1 LOC114031690 LOC114031690 ENSVURP00010017930 ENSVURP00010017930 ENSVURP00010018047 ENSVURP00010018047 ENSVURP00010018054 ENSVURP00010018054 ENSVURP00010018107 ENSVURP00010018107 DLG5 DLG5 IL12RB2 IL12RB2 ENSVURP00010018452 ENSVURP00010018452 ATM ATM ENSVURP00010018786 ENSVURP00010018786 IL2 IL2 IL21 IL21 JAK3 JAK3 ENSVURP00010019467 ENSVURP00010019467 PRKCQ PRKCQ LOC114052665 LOC114052665 CCL19 CCL19 TCF3 TCF3 LOC114049705 LOC114049705 VAV3 VAV3 ANXA1 ANXA1 ENSVURP00010021437 ENSVURP00010021437 CD40LG CD40LG IL12A IL12A CD40 CD40 ZNF335 ZNF335 LRRC32 LRRC32 RPS3 RPS3 TLR9 TLR9 SLC39A10 SLC39A10 MEF2C MEF2C ENSVURP00010023487 ENSVURP00010023487 ENSVURP00010023734 ENSVURP00010023734 GPR183 GPR183 NFATC2 NFATC2 ENSVURP00010024661 ENSVURP00010024661 ENSVURP00010024670 ENSVURP00010024670 ENSVURP00010024679 ENSVURP00010024679 CARD11 CARD11 HHEX HHEX ITCH ITCH MAD1L1 MAD1L1 CDKN1A CDKN1A LOC114032095 LOC114032095 IL18 IL18 MPL MPL ENSVURP00010026284 ENSVURP00010026284 ENSVURP00010026291 ENSVURP00010026291 ENSVURP00010026384 ENSVURP00010026384 ENSVURP00010026522 ENSVURP00010026522 SLC7A1 SLC7A1 FOXP3 FOXP3 IL6ST IL6ST ENSVURP00010028427 ENSVURP00010028427 CTNNB1 CTNNB1 MAPK1 MAPK1 ENSVURP00010028558 ENSVURP00010028558 ENSVURP00010028631 ENSVURP00010028631 TIRAP TIRAP LOC114032988 LOC114032988 ENSVURP00010028996 ENSVURP00010028996 ENSVURP00010029311 ENSVURP00010029311 INPP5D INPP5D ENSVURP00010029376 ENSVURP00010029376 ENSVURP00010029395 ENSVURP00010029395 ENSVURP00010029419 ENSVURP00010029419 TGFBR2 TGFBR2 ENSVURP00010029660 ENSVURP00010029660 ENSVURP00010029663 ENSVURP00010029663 ENSVURP00010029673 ENSVURP00010029673 ENSVURP00010029680 ENSVURP00010029680 BMI1 BMI1 ENSVURP00010030457 ENSVURP00010030457 ARG1 ARG1 BCL6 BCL6 ARG2 ARG2 CD22 CD22 TMEM147 TMEM147 TYROBP TYROBP TNFRSF4 TNFRSF4 STAT6 STAT6 IL23A IL23A PLA2G2F PLA2G2F PLA2G2D PLA2G2D IGF1 IGF1 TNFRSF1B TNFRSF1B TNFRSF9 TNFRSF9 ENSVURP00010031693 ENSVURP00010031693 PKN1 PKN1 ENSVURP00010031879 ENSVURP00010031879 FADD FADD TMIGD2 TMIGD2 ENSVURP00010032390 ENSVURP00010032390 CLCF1 CLCF1 ZAP70 ZAP70 SCRIB SCRIB RASAL3 RASAL3 GPAM GPAM
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSVURP00010029447Tyrosine-protein kinase. (1149 aa)
SASH3Uncharacterized protein. (394 aa)
IL34Uncharacterized protein. (247 aa)
GLMNUncharacterized protein. (604 aa)
OCSTAMPDC_STAMP domain-containing protein. (464 aa)
PAWRUncharacterized protein. (373 aa)
IHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (410 aa)
ADAA_deaminase domain-containing protein. (362 aa)
BST1Uncharacterized protein. (319 aa)
SOS1Uncharacterized protein. (1332 aa)
LOC114050496PKD domain-containing protein. (530 aa)
AIF1EF-hand domain-containing protein. (147 aa)
PTPN6Protein tyrosine phosphatase non-receptor type 6. (578 aa)
SDC4Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (197 aa)
LOC114050566Uncharacterized protein. (215 aa)
ST6GAL1Uncharacterized protein; Belongs to the glycosyltransferase 29 family. (396 aa)
BTKTyrosine-protein kinase. (659 aa)
CRTAMUncharacterized protein. (390 aa)
IGFBP2Uncharacterized protein. (318 aa)
NMBRG_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (390 aa)
SPTA1Uncharacterized protein. (2408 aa)
ENSVURP00010003617Uncharacterized protein. (149 aa)
ZP3ZP domain-containing protein. (419 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (382 aa)
CD6Uncharacterized protein. (633 aa)
ENSVURP00010004342Uncharacterized protein. (891 aa)
ENSVURP00010004384Uncharacterized protein. (189 aa)
LOC114046276Cytoplasmic protein. (380 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
MARCH7RING-CH-type domain-containing protein. (762 aa)
PTHParathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion. (115 aa)
VSIG4Uncharacterized protein. (447 aa)
TNFRSF21Uncharacterized protein. (671 aa)
CSF2RBUncharacterized protein. (897 aa)
LOC114046290TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (298 aa)
PTPRCUncharacterized protein. (1300 aa)
CCDC88BUncharacterized protein. (1487 aa)
ENSVURP00010006162KH type-2 domain-containing protein. (90 aa)
ENSVURP00010006200Ig-like domain-containing protein. (259 aa)
RIPK2Uncharacterized protein. (540 aa)
AGERUncharacterized protein. (412 aa)
CTLA4IGv domain-containing protein. (223 aa)
CD28IGv domain-containing protein. (221 aa)
ENSVURP00010007254Uncharacterized protein. (183 aa)
ENSVURP00010007328Uncharacterized protein. (312 aa)
IKZF3Uncharacterized protein. (558 aa)
RC3H1Uncharacterized protein. (1134 aa)
IRF1Interferon regulatory factor. (325 aa)
ENSVURP00010007928KH type-2 domain-containing protein. (161 aa)
LOC114053900Tyrosine-protein kinase. (514 aa)
CD274Ig-like domain-containing protein. (272 aa)
JAK2Tyrosine-protein kinase. (1132 aa)
SYKUncharacterized protein. (639 aa)
ENSVURP00010009759annotation not available (380 aa)
CD74Thyroglobulin type-1 domain-containing protein. (275 aa)
TFRCUncharacterized protein. (770 aa)
BLKTyrosine-protein kinase. (502 aa)
LOC114025005Ig-like domain-containing protein. (266 aa)
CSF1RUncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (959 aa)
NCKAP1LUncharacterized protein. (1134 aa)
VTCN1Uncharacterized protein. (324 aa)
ENSVURP00010010956Uncharacterized protein. (224 aa)
CORO1ACoronin; Belongs to the WD repeat coronin family. (461 aa)
NCK1Cytoplasmic protein. (377 aa)
IL20RBFibronectin type-III domain-containing protein. (312 aa)
ENSVURP00010011128annotation not available (224 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (299 aa)
GREM1Gremlin. (184 aa)
SH3RF1Uncharacterized protein. (868 aa)
NDFIP1Uncharacterized protein. (276 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (467 aa)
LGALS3Galectin. (280 aa)
SOS2Uncharacterized protein. (1329 aa)
LRRC1Leucine rich repeat containing 1. (745 aa)
ENSVURP00010012358KH type-2 domain-containing protein. (144 aa)
IDO1Uncharacterized protein. (399 aa)
IL15Interleukin; Belongs to the IL-15/IL-21 family. (183 aa)
ENSVURP00010013239Uncharacterized protein. (81 aa)
KITUncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (997 aa)
ENSVURP00010013836A_deaminase domain-containing protein. (249 aa)
ENSVURP00010014207Galectin. (307 aa)
LOC114042866Galectin. (356 aa)
FOXJ1Fork-head domain-containing protein. (418 aa)
MAPK8IP1Mitogen-activated protein kinase 8 interacting protein 1. (715 aa)
NF1Neurofibromin 1. (2841 aa)
LOC114040884Uncharacterized protein. (196 aa)
LOC114040819Uncharacterized protein. (200 aa)
ENSVURP00010015264ATPase_AAA_core domain-containing protein. (1410 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (540 aa)
MYD88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (318 aa)
IGF2IlGF domain-containing protein. (226 aa)
ENSVURP00010015540Ig-like domain-containing protein. (359 aa)
PRNPMajor prion protein; Belongs to the prion family. (257 aa)
TSPAN32Uncharacterized protein; Belongs to the tetraspanin (TM4SF) family. (239 aa)
CD81Uncharacterized protein; Belongs to the tetraspanin (TM4SF) family. (299 aa)
TMEM131LUncharacterized protein. (1474 aa)
IL10Uncharacterized protein. (206 aa)
DHPSUncharacterized protein. (377 aa)
RASSF5Uncharacterized protein. (418 aa)
VSIRIg-like domain-containing protein. (348 aa)
EFNB1Ephrin B1; Belongs to the ephrin family. (443 aa)
BCL2BCL2 apoptosis regulator. (256 aa)
PELI1E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (418 aa)
CSF1Uncharacterized protein. (561 aa)
LOC114031690Uncharacterized protein. (222 aa)
ENSVURP00010017930Uncharacterized protein. (876 aa)
ENSVURP00010018047Uncharacterized protein. (404 aa)
ENSVURP00010018054Ig-like domain-containing protein. (387 aa)
ENSVURP00010018107ZP domain-containing protein. (401 aa)
DLG5Uncharacterized protein; Belongs to the MAGUK family. (2030 aa)
IL12RB2Uncharacterized protein. (865 aa)
ENSVURP00010018452Uncharacterized protein. (634 aa)
ATMSerine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3064 aa)
ENSVURP00010018786A_deaminase domain-containing protein. (85 aa)
IL2Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (141 aa)
IL21Interleukin; Belongs to the IL-15/IL-21 family. (154 aa)
JAK3Tyrosine-protein kinase. (1110 aa)
ENSVURP00010019467Uncharacterized protein. (274 aa)
PRKCQProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (686 aa)
LOC114052665Uncharacterized protein. (284 aa)
CCL19C-C motif chemokine. (101 aa)
TCF3BHLH domain-containing protein. (661 aa)
LOC114049705Uncharacterized protein. (528 aa)
VAV3Uncharacterized protein. (873 aa)
ANXA1Annexin. (346 aa)
ENSVURP00010021437Amine oxidase. (527 aa)
CD40LGCD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching. (253 aa)
IL12AInterleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (215 aa)
CD40Uncharacterized protein. (276 aa)
ZNF335Uncharacterized protein. (1400 aa)
LRRC32Uncharacterized protein. (670 aa)
RPS3KH type-2 domain-containing protein; Belongs to the universal ribosomal protein uS3 family. (243 aa)
TLR9TIR domain-containing protein. (1041 aa)
SLC39A10Uncharacterized protein. (846 aa)
MEF2CMADS-box domain-containing protein. (483 aa)
ENSVURP00010023487TACI-CRD2 domain-containing protein. (244 aa)
ENSVURP00010023734KH type-2 domain-containing protein. (123 aa)
GPR183G protein-coupled receptor 183; Belongs to the G-protein coupled receptor 1 family. (358 aa)
NFATC2RHD domain-containing protein. (924 aa)
ENSVURP00010024661FERM domain-containing protein. (121 aa)
ENSVURP00010024670Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (455 aa)
ENSVURP00010024679Focal_AT domain-containing protein. (115 aa)
CARD11Uncharacterized protein. (1151 aa)
HHEXHomeobox domain-containing protein. (277 aa)
ITCHE3 ubiquitin-protein ligase. (872 aa)
MAD1L1FtsJ domain-containing protein. (841 aa)
CDKN1AUncharacterized protein. (164 aa)
LOC114032095Uncharacterized protein. (208 aa)
IL18Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (198 aa)
MPLMPL proto-oncogene, thrombopoietin receptor. (651 aa)
ENSVURP00010026284Uncharacterized protein. (330 aa)
ENSVURP00010026291annotation not available (530 aa)
ENSVURP00010026384annotation not available (215 aa)
ENSVURP00010026522annotation not available (514 aa)
SLC7A1AA_permease_C domain-containing protein. (624 aa)
FOXP3Fork-head domain-containing protein. (452 aa)
IL6STUncharacterized protein. (921 aa)
ENSVURP00010028427annotation not available (762 aa)
CTNNB1Catenin beta 1. (744 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (349 aa)
ENSVURP00010028558SH2 domain-containing protein. (618 aa)
ENSVURP00010028631SH2 domain-containing protein. (602 aa)
TIRAPTIR domain containing adaptor protein. (217 aa)
LOC114032988Uncharacterized protein. (103 aa)
ENSVURP00010028996Uncharacterized protein. (517 aa)
ENSVURP00010029311annotation not available (222 aa)
INPP5DSH2 domain-containing protein. (1190 aa)
ENSVURP00010029376annotation not available (298 aa)
ENSVURP00010029395annotation not available (103 aa)
ENSVURP00010029419Tyrosine-protein kinase. (1180 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (565 aa)
ENSVURP00010029660Uncharacterized protein. (92 aa)
ENSVURP00010029663annotation not available (92 aa)
ENSVURP00010029673C2-set_2 domain-containing protein. (246 aa)
ENSVURP00010029680annotation not available (246 aa)
BMI1RING-type domain-containing protein. (327 aa)
ENSVURP00010030457Galectin. (257 aa)
ARG1Arginase. (315 aa)
BCL6Uncharacterized protein. (737 aa)
ARG2Arginase. (353 aa)
CD22Uncharacterized protein. (841 aa)
TMEM147Uncharacterized protein. (225 aa)
TYROBPTYRO protein tyrosine kinase binding protein. (105 aa)
TNFRSF4Uncharacterized protein. (277 aa)
STAT6Signal transducer and activator of transcription. (843 aa)
IL23AInterleukin 23 subunit alpha. (188 aa)
PLA2G2FPhospholipase A(2). (218 aa)
PLA2G2DPhospholipase A(2). (145 aa)
IGF1Insulin like growth factor 1. (229 aa)
TNFRSF1BUncharacterized protein. (472 aa)
TNFRSF9TNFR-Cys domain-containing protein. (276 aa)
ENSVURP00010031693Uncharacterized protein. (365 aa)
PKN1Uncharacterized protein. (1023 aa)
ENSVURP00010031879TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (305 aa)
FADDUncharacterized protein. (193 aa)
TMIGD2Ig-like domain-containing protein. (248 aa)
ENSVURP00010032390Uncharacterized protein. (279 aa)
CLCF1Cardiotrophin like cytokine factor 1. (222 aa)
ZAP70Tyrosine-protein kinase. (617 aa)
SCRIBUncharacterized protein. (1704 aa)
RASAL3Ras-GAP domain-containing protein. (1003 aa)
GPAMGlycerol-3-phosphate acyltransferase 1, mitochondrial. (830 aa)
Your Current Organism:
Vombatus ursinus
NCBI taxonomy Id: 29139
Other names: V. ursinus, coarse-haired wombat, common wombat
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