39 items (Vombatus ursinus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	EGFR	Receptor protein-tyrosine kinase. (1214 aa)
	LOC114040362	Uncharacterized protein. (99 aa)
	ENSVURP00010015428	Uncharacterized protein. (105 aa)
	ENSVURP00010015425	annotation not available (125 aa)
	ENSVURP00010015416	DSPc domain-containing protein. (125 aa)
	TPR	Translocated promoter region, nuclear basket protein. (2318 aa)
	BAG4	BCL2 associated athanogene 4. (447 aa)
	BAIAP2	Uncharacterized protein. (543 aa)
	ENSVURP00010010914	Ras-GAP domain-containing protein. (865 aa)
	MAPK3	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
	INPP5K	IPPc domain-containing protein. (598 aa)
	ENSVURP00010010529	Uncharacterized protein. (167 aa)
	MED1	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1582 aa)
	ERBB2	Receptor protein-tyrosine kinase. (1255 aa)
	ENSVURP00010006631	annotation not available (268 aa)
	ENSVURP00010006081	Uncharacterized protein. (62 aa)
	PTPN11	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
	ENSVURP00010004457	annotation not available (875 aa)
	LOC114031883	CABIT domain-containing protein. (875 aa)
	LOC114043698	Protein kinase domain-containing protein. (683 aa)
	LOC114031844	Uncharacterized protein. (268 aa)
	VIL1	HP domain-containing protein. (827 aa)
	DAB2	PID domain-containing protein. (767 aa)
	GAREM2	CABIT domain-containing protein. (879 aa)
	SYAP1	Synapse associated protein 1. (286 aa)
	ZFP36L2	ZFP36 ring finger protein like 2. (503 aa)
	ENSVURP00010021023	annotation not available (683 aa)
	VILL	Uncharacterized protein. (841 aa)
	ENSVURP00010021832	annotation not available (865 aa)
	MAPK1	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (349 aa)
	ENSVURP00010029468	IPPc domain-containing protein. (375 aa)
	NCL	Uncharacterized protein. (694 aa)
	MARS1	Uncharacterized protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (907 aa)
	ZFP36	Uncharacterized protein. (374 aa)
	ZFP36L1	Uncharacterized protein. (338 aa)
	LOC114038227	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (643 aa)
	ERRFI1	ERBB receptor feedback inhibitor 1. (464 aa)
	ZPR1	Uncharacterized protein. (517 aa)
	PLCG1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1279 aa)

Your Current Organism:

Vombatus ursinus

NCBI taxonomy Id: 29139
Other names: V. ursinus, coarse-haired wombat, common wombat

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BAG4	PLCG1	ENSVURP00010013274	ENSVURP00010018456	BCL2 associated athanogene 4.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.432
BAIAP2	EGFR	ENSVURP00010012220	ENSVURP00010017895	Uncharacterized protein.	Receptor protein-tyrosine kinase.	0.810
BAIAP2	MAPK1	ENSVURP00010012220	ENSVURP00010028502	Uncharacterized protein.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.618
BAIAP2	MAPK3	ENSVURP00010012220	ENSVURP00010011204	Uncharacterized protein.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.618
DAB2	EGFR	ENSVURP00010002125	ENSVURP00010017895	PID domain-containing protein.	Receptor protein-tyrosine kinase.	0.707
DAB2	ENSVURP00010010914	ENSVURP00010002125	ENSVURP00010010914	PID domain-containing protein.	Ras-GAP domain-containing protein.	0.632
DAB2	ENSVURP00010021832	ENSVURP00010002125	ENSVURP00010021832	PID domain-containing protein.	annotation not available	0.632
DAB2	ERBB2	ENSVURP00010002125	ENSVURP00010007604	PID domain-containing protein.	Receptor protein-tyrosine kinase.	0.667
EGFR	BAIAP2	ENSVURP00010017895	ENSVURP00010012220	Receptor protein-tyrosine kinase.	Uncharacterized protein.	0.810
EGFR	DAB2	ENSVURP00010017895	ENSVURP00010002125	Receptor protein-tyrosine kinase.	PID domain-containing protein.	0.707
EGFR	ENSVURP00010010914	ENSVURP00010017895	ENSVURP00010010914	Receptor protein-tyrosine kinase.	Ras-GAP domain-containing protein.	0.561
EGFR	ENSVURP00010021832	ENSVURP00010017895	ENSVURP00010021832	Receptor protein-tyrosine kinase.	annotation not available	0.561
EGFR	ERBB2	ENSVURP00010017895	ENSVURP00010007604	Receptor protein-tyrosine kinase.	Receptor protein-tyrosine kinase.	0.998
EGFR	LOC114038227	ENSVURP00010017895	ENSVURP00010030838	Receptor protein-tyrosine kinase.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.996
EGFR	NCL	ENSVURP00010017895	ENSVURP00010029517	Receptor protein-tyrosine kinase.	Uncharacterized protein.	0.646
EGFR	PLCG1	ENSVURP00010017895	ENSVURP00010018456	Receptor protein-tyrosine kinase.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.994
EGFR	PTPN11	ENSVURP00010017895	ENSVURP00010004876	Receptor protein-tyrosine kinase.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.996
EGFR	ZPR1	ENSVURP00010017895	ENSVURP00010032024	Receptor protein-tyrosine kinase.	Uncharacterized protein.	0.559
ENSVURP00010004457	GAREM2	ENSVURP00010004457	ENSVURP00010000649	annotation not available	CABIT domain-containing protein.	0.430
ENSVURP00010006081	MAPK1	ENSVURP00010006081	ENSVURP00010028502	Uncharacterized protein.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.637