(17 nodes) TRAF-like network (Vombatus ursinus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	TRIM37	Tripartite motif containing 37. (979 aa)
	SIAH1	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (313 aa)
	SIAH3	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (271 aa)
	USP7	Uncharacterized protein; Belongs to the peptidase C19 family. (1100 aa)
	TRAF3	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (567 aa)
	LOC114025034	Meprin A subunit. (706 aa)
	ENSVURP00010004367	Meprin A subunit. (689 aa)
	TRAF2	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (633 aa)
	SPOPL	Uncharacterized protein. (394 aa)
	LOC114046849	RING-type domain-containing protein. (416 aa)
	SPOP	Uncharacterized protein. (374 aa)
	ENSVURP00010000918	Uncharacterized protein. (188 aa)
	ENSVURP00010004099	Meprin A subunit. (686 aa)
	TRAF4	TNF receptor-associated factor. (470 aa)
	SIAH2	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (341 aa)
	TRAF5	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (560 aa)
	TRAF6	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (540 aa)

Your Current Organism:

Vombatus ursinus

NCBI taxonomy Id: 29139
Other names: V. ursinus, coarse-haired wombat, common wombat

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSVURP00010000918	LOC114046849	ENSVURP00010000918	ENSVURP00010010184	Uncharacterized protein.	RING-type domain-containing protein.	0.626
ENSVURP00010000918	TRAF2	ENSVURP00010000918	ENSVURP00010007645	Uncharacterized protein.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.626
ENSVURP00010000918	TRAF3	ENSVURP00010000918	ENSVURP00010005741	Uncharacterized protein.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.625
ENSVURP00010000918	TRAF5	ENSVURP00010000918	ENSVURP00010015234	Uncharacterized protein.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.626
ENSVURP00010000918	TRAF6	ENSVURP00010000918	ENSVURP00010015322	Uncharacterized protein.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.554
ENSVURP00010000918	USP7	ENSVURP00010000918	ENSVURP00010012704	Uncharacterized protein.	Uncharacterized protein; Belongs to the peptidase C19 family.	0.753
ENSVURP00010004099	LOC114025034	ENSVURP00010004099	ENSVURP00010005437	Meprin A subunit.	Meprin A subunit.	0.829
ENSVURP00010004367	LOC114025034	ENSVURP00010004367	ENSVURP00010005437	Meprin A subunit.	Meprin A subunit.	0.829
LOC114025034	ENSVURP00010004099	ENSVURP00010005437	ENSVURP00010004099	Meprin A subunit.	Meprin A subunit.	0.829
LOC114025034	ENSVURP00010004367	ENSVURP00010005437	ENSVURP00010004367	Meprin A subunit.	Meprin A subunit.	0.829
LOC114046849	ENSVURP00010000918	ENSVURP00010010184	ENSVURP00010000918	RING-type domain-containing protein.	Uncharacterized protein.	0.626
LOC114046849	TRAF3	ENSVURP00010010184	ENSVURP00010005741	RING-type domain-containing protein.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.963
LOC114046849	TRAF4	ENSVURP00010010184	ENSVURP00010013297	RING-type domain-containing protein.	TNF receptor-associated factor.	0.626
LOC114046849	TRAF5	ENSVURP00010010184	ENSVURP00010015234	RING-type domain-containing protein.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.918
LOC114046849	TRAF6	ENSVURP00010010184	ENSVURP00010015322	RING-type domain-containing protein.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.971
LOC114046849	USP7	ENSVURP00010010184	ENSVURP00010012704	RING-type domain-containing protein.	Uncharacterized protein; Belongs to the peptidase C19 family.	0.610
SIAH1	SIAH2	ENSVURP00010017948	ENSVURP00010014674	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.	0.918
SIAH2	SIAH1	ENSVURP00010014674	ENSVURP00010017948	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.	0.918
SPOP	SPOPL	ENSVURP00010010191	ENSVURP00010007925	Uncharacterized protein.	Uncharacterized protein.	0.923
SPOP	USP7	ENSVURP00010010191	ENSVURP00010012704	Uncharacterized protein.	Uncharacterized protein; Belongs to the peptidase C19 family.	0.414