65 items (Vombatus ursinus) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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co-expression

protein homology

Your Input:
	CASP8	Uncharacterized protein; Belongs to the peptidase C14A family. (471 aa)
	NMT1	Glycylpeptide N-tetradecanoyltransferase; Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins; Belongs to the NMT family. (500 aa)
	ENSVURP00010012375	Dynein light chain. (56 aa)
	AVEN	Apoptosis and caspase activation inhibitor. (366 aa)
	ENSVURP00010013115	Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (103 aa)
	CASP7	Uncharacterized protein; Belongs to the peptidase C14A family. (305 aa)
	APAF1	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1251 aa)
	BID	BH3-interacting domain death agonist; Counters the protective effect of Bcl-2. (191 aa)
	LOC114037947	DUF4203 domain-containing protein. (349 aa)
	LOC114040557	Uncharacterized protein; Belongs to the peptidase C14A family. (276 aa)
	ENSVURP00010029953	Uncharacterized protein; Belongs to the peptidase C14A family. (274 aa)
	MAPK1	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (349 aa)
	BOK	Uncharacterized protein. (249 aa)
	BCL2L2	BH4_2 domain-containing protein. (193 aa)
	ENSVURP00010025967	annotation not available (503 aa)
	ENSVURP00010025890	Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (91 aa)
	ENSVURP00010025872	annotation not available (181 aa)
	CUNH6orf222	Uncharacterized protein. (476 aa)
	ENSVURP00010024626	Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (96 aa)
	SEPTIN1	Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (365 aa)
	ENSVURP00010022661	Dynein light chain. (79 aa)
	TMEM198	DUF4203 domain-containing protein. (360 aa)
	BAK1	Uncharacterized protein. (204 aa)
	YWHAQ	14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (245 aa)
	BCL2L11	BCL2 like 11. (141 aa)
	SEPT5	Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (370 aa)
	ENSVURP00010019921	14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (96 aa)
	ENSVURP00010018359	annotation not available (227 aa)
	DYNLL2	Dynein light chain. (89 aa)
	ENSVURP00010017559	Uncharacterized protein. (185 aa)
	BAX	Uncharacterized protein. (200 aa)
	BCL2	BCL2 apoptosis regulator. (256 aa)
	SEPT4	Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (470 aa)
	PPP3R1	Uncharacterized protein. (170 aa)
	FILIP1L	Filamin A interacting protein 1 like. (1133 aa)
	ENSVURP00010015670	Uncharacterized protein. (128 aa)
	APIP	Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway, which plays a key role in cancer, apoptosis, microbial proliferation and inflammation. May inhibit the CASP1-related inflammatory response (pyroptosis), the CASP9-dependent apoptotic pathway and the cytochrome c-dependent and APAF1-mediated cell death; Belongs to the aldolase class II family. MtnB subfamily. (243 aa)
	ENSVURP00010015181	Uncharacterized protein. (100 aa)
	DIABLO	Uncharacterized protein. (248 aa)
	XIAP	RING-type domain-containing protein. (498 aa)
	BAD	Uncharacterized protein. (180 aa)
	BCL2L10	Uncharacterized protein. (188 aa)
	GSDMB	Gasdermin domain-containing protein. (258 aa)
	DYNLL1	Dynein light chain. (89 aa)
	ENSVURP00010008908	CASPASE_P20 domain-containing protein; Belongs to the peptidase C14A family. (190 aa)
	SFN	14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (254 aa)
	YWHAZ	14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (245 aa)
	ENSVURP00010009165	14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (212 aa)
	LOC114034312	Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
	LOC114037676	Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
	YWHAE	14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (255 aa)
	BMF	Uncharacterized protein. (184 aa)
	MAPK3	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
	CASP10	Uncharacterized protein; Belongs to the peptidase C14A family. (490 aa)
	ENSVURP00010000102	14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (231 aa)
	ENSVURP00010000112	annotation not available (231 aa)
	ENSVURP00010000617	Uncharacterized protein. (181 aa)
	LOC114050697	Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
	LOC114050617	Uncharacterized protein. (503 aa)
	CASP9	Uncharacterized protein; Belongs to the peptidase C14A family. (424 aa)
	YWHAB	14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (263 aa)
	LOC114026424	Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa)
	LOC114047093	BH4_2 domain-containing protein. (227 aa)
	YWHAG	14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (247 aa)
	ENSVURP00010004866	14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (125 aa)

Your Current Organism:

Vombatus ursinus

NCBI taxonomy Id: 29139
Other names: V. ursinus, coarse-haired wombat, common wombat

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APAF1	APIP	ENSVURP00010031552	ENSVURP00010015500	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway, which plays a key role in cancer, apoptosis, microbial proliferation and inflammation. May inhibit the CASP1-related inflammatory response (pyroptosis), the CASP9-dependent apoptotic pathway and the cytochrome c-dependent and APAF1-mediated cell death; Belongs to the aldolase class II family. MtnB subfamily.	0.953
APAF1	AVEN	ENSVURP00010031552	ENSVURP00010013063	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	Apoptosis and caspase activation inhibitor.	0.988
APAF1	BAK1	ENSVURP00010031552	ENSVURP00010020955	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	Uncharacterized protein.	0.878
APAF1	BAX	ENSVURP00010031552	ENSVURP00010017144	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	Uncharacterized protein.	0.912
APAF1	BCL2	ENSVURP00010031552	ENSVURP00010017005	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	BCL2 apoptosis regulator.	0.915
APAF1	BCL2L10	ENSVURP00010031552	ENSVURP00010006264	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	Uncharacterized protein.	0.867
APAF1	BCL2L11	ENSVURP00010031552	ENSVURP00010020643	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	BCL2 like 11.	0.575
APAF1	BCL2L2	ENSVURP00010031552	ENSVURP00010027079	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	BH4_2 domain-containing protein.	0.878
APAF1	BOK	ENSVURP00010031552	ENSVURP00010027678	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	Uncharacterized protein.	0.867
APAF1	CASP10	ENSVURP00010031552	ENSVURP00010011302	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.977
APAF1	CASP7	ENSVURP00010031552	ENSVURP00010032818	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.979
APAF1	CASP8	ENSVURP00010031552	ENSVURP00010011270	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.977
APAF1	CASP9	ENSVURP00010031552	ENSVURP00010001690	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.998
APAF1	CUNH6orf222	ENSVURP00010031552	ENSVURP00010025243	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	Uncharacterized protein.	0.867
APAF1	DIABLO	ENSVURP00010031552	ENSVURP00010005161	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	Uncharacterized protein.	0.854
APAF1	ENSVURP00010000617	ENSVURP00010031552	ENSVURP00010000617	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	Uncharacterized protein.	0.977
APAF1	ENSVURP00010008908	ENSVURP00010031552	ENSVURP00010008908	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	CASPASE_P20 domain-containing protein; Belongs to the peptidase C14A family.	0.984
APAF1	ENSVURP00010013115	ENSVURP00010031552	ENSVURP00010013115	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	0.984
APAF1	ENSVURP00010015670	ENSVURP00010031552	ENSVURP00010015670	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	Uncharacterized protein.	0.854
APAF1	ENSVURP00010017559	ENSVURP00010031552	ENSVURP00010017559	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	Uncharacterized protein.	0.889