STRINGSTRING
CHD4 CHD4 MAPK15 MAPK15 MAP2K2 MAP2K2 ENSVURP00010032211 ENSVURP00010032211 ASCL1 ASCL1 CREM CREM TRIB2 TRIB2 NAB2 NAB2 FNDC3A FNDC3A ID3 ID3 AP2M1 AP2M1 ENSVURP00010029610 ENSVURP00010029610 ENSVURP00010029292 ENSVURP00010029292 ENSVURP00010029009 ENSVURP00010029009 ENSVURP00010028896 ENSVURP00010028896 MAPK1 MAPK1 CRKL CRKL DUSP3 DUSP3 PPP4R4 PPP4R4 RELCH RELCH LOC114025658-2 LOC114025658-2 PPP2R1B PPP2R1B PIK3R1 PIK3R1 MAPK14 MAPK14 ARC ARC LOC114034866 LOC114034866 NTF3 NTF3 MAPKAPK3 MAPKAPK3 DOCK3 DOCK3 MAP2K5 MAP2K5 NAB1 NAB1 PTPRO PTPRO ENSVURP00010022784 ENSVURP00010022784 MAP2K1 MAP2K1 DUSP7 DUSP7 PCSK4 PCSK4 ENSVURP00010020687 ENSVURP00010020687 ENSVURP00010020577 ENSVURP00010020577 DUSP6 DUSP6 LOC114025658 LOC114025658 CLTCL1 CLTCL1 KRAS KRAS JUND JUND EGR3 EGR3 PIK3R2 PIK3R2 RIT1 RIT1 BRAF BRAF PLCG1 PLCG1 AP2A1 AP2A1 NTRK1 NTRK1 ENSVURP00010017741 ENSVURP00010017741 RPS6KA5 RPS6KA5 LOC114031856 LOC114031856 BAX BAX ENSVURP00010017057 ENSVURP00010017057 NTF4 NTF4 FNDC3B FNDC3B RALA RALA LYL1 LYL1 PIK3CA PIK3CA CLTC CLTC RAPGEF1 RAPGEF1 JUNB JUNB LOC114043375 LOC114043375 MAPKAPK2 MAPKAPK2 RALGDS RALGDS ENSVURP00010015742 ENSVURP00010015742 PPP2CB PPP2CB GRB2 GRB2 RPS6KA3 RPS6KA3 ENSVURP00010015212 ENSVURP00010015212 ENSVURP00010015196 ENSVURP00010015196 ENSVURP00010015187 ENSVURP00010015187 RALB RALB CLTA CLTA LOC114030907 LOC114030907 RPS6KA2 RPS6KA2 ENSVURP00010013724 ENSVURP00010013724 ENSVURP00010013703 ENSVURP00010013703 KIDINS220 KIDINS220 ID2 ID2 ENSVURP00010013014 ENSVURP00010013014 LOC114027938 LOC114027938 FNBP4 FNBP4 NRAS NRAS CSDE1 CSDE1 PCSK6 PCSK6 ENSVURP00010012020 ENSVURP00010012020 EGR1 EGR1 PPP2R1A PPP2R1A PIK3CB PIK3CB MAPK3 MAPK3 NGF NGF NTRK3 NTRK3 PPP2CA PPP2CA ATF1 ATF1 RPS6KA1 RPS6KA1 ENSVURP00010008520 ENSVURP00010008520 FURIN FURIN SHC4 SHC4 SRF SRF MAPK7 MAPK7 ENSVURP00010007321 ENSVURP00010007321 FRS2 FRS2 AP2A2 AP2A2 HRAS HRAS CREB1 CREB1 RPS6KA4 RPS6KA4 SGK1 SGK1 ENSVURP00010004670 ENSVURP00010004670 DNAL4 DNAL4 MAPK11 MAPK11 ID4 ID4 SOS1 SOS1 YWHAB YWHAB FOSL1 FOSL1 ENSVURP00010001268 ENSVURP00010001268 BDNF BDNF ENSVURP00010000873 ENSVURP00010000873 EGR4 EGR4 NKPD1 NKPD1 EGR2 EGR2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CHD4Uncharacterized protein. (1938 aa)
MAPK15Mitogen-activated protein kinase 15. (545 aa)
MAP2K2Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (400 aa)
ENSVURP00010032211Serine/threonine-protein phosphatase. (309 aa)
ASCL1BHLH domain-containing protein. (249 aa)
CREMUncharacterized protein. (332 aa)
TRIB2Protein kinase domain-containing protein. (343 aa)
NAB2Uncharacterized protein. (519 aa)
FNDC3AUncharacterized protein. (1204 aa)
ID3BHLH domain-containing protein. (118 aa)
AP2M1MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family. (437 aa)
ENSVURP00010029610annotation not available (142 aa)
ENSVURP00010029292annotation not available (956 aa)
ENSVURP00010029009Uncharacterized protein. (566 aa)
ENSVURP00010028896Uncharacterized protein. (109 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (349 aa)
CRKLUncharacterized protein. (303 aa)
DUSP3Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (182 aa)
PPP4R4Uncharacterized protein. (871 aa)
RELCHRAB11 binding and LisH domain, coiled-coil and HEAT repeat containing. (1212 aa)
LOC114025658-2Tyrosine-protein kinase receptor. (824 aa)
PPP2R1BUncharacterized protein. (662 aa)
PIK3R1Uncharacterized protein. (725 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
ARCArc_C domain-containing protein. (400 aa)
LOC114034866WRNPLPNID domain-containing protein. (943 aa)
NTF3Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (268 aa)
MAPKAPK3Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (395 aa)
DOCK3Uncharacterized protein; Belongs to the DOCK family. (2015 aa)
MAP2K5Uncharacterized protein; Belongs to the protein kinase superfamily. (448 aa)
NAB1Uncharacterized protein. (498 aa)
PTPROProtein tyrosine phosphatase receptor type O. (1100 aa)
ENSVURP00010022784P/Homo B domain-containing protein; Belongs to the peptidase S8 family. (836 aa)
MAP2K1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (393 aa)
DUSP7Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (378 aa)
PCSK4P/Homo B domain-containing protein; Belongs to the peptidase S8 family. (773 aa)
ENSVURP00010020687Uncharacterized protein. (578 aa)
ENSVURP00010020577annotation not available (951 aa)
DUSP6Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (382 aa)
LOC114025658Tyrosine-protein kinase receptor. (821 aa)
CLTCL1Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1672 aa)
KRASUncharacterized protein. (189 aa)
JUNDJunD proto-oncogene, AP-1 transcription factor subunit. (307 aa)
EGR3Uncharacterized protein. (386 aa)
PIK3R2Uncharacterized protein. (738 aa)
RIT1Ras like without CAAX 1. (228 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (741 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1279 aa)
AP2A1AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (973 aa)
NTRK1Tyrosine-protein kinase receptor. (743 aa)
ENSVURP00010017741Protein kinase domain-containing protein. (369 aa)
RPS6KA5Ribosomal protein S6 kinase. (799 aa)
LOC114031856WRNPLPNID domain-containing protein. (956 aa)
BAXUncharacterized protein. (200 aa)
ENSVURP00010017057ETS domain-containing protein. (95 aa)
NTF4Neurotrophin 4; Belongs to the NGF-beta family. (204 aa)
FNDC3BUncharacterized protein. (1211 aa)
RALAUncharacterized protein. (206 aa)
LYL1LYL1 basic helix-loop-helix family member. (308 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
CLTCClathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1679 aa)
RAPGEF1Uncharacterized protein. (1124 aa)
JUNBBZIP domain-containing protein. (360 aa)
LOC114043375AP complex subunit beta. (951 aa)
MAPKAPK2Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (422 aa)
RALGDSUncharacterized protein. (827 aa)
ENSVURP00010015742BHLH domain-containing protein. (241 aa)
PPP2CBSerine/threonine-protein phosphatase. (309 aa)
GRB2Uncharacterized protein. (217 aa)
RPS6KA3Ribosomal protein S6 kinase. (740 aa)
ENSVURP00010015212Protein kinase domain-containing protein. (364 aa)
ENSVURP00010015196PID domain-containing protein. (300 aa)
ENSVURP00010015187SH2 domain-containing protein. (98 aa)
RALBUncharacterized protein. (206 aa)
CLTAClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (223 aa)
LOC114030907AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (142 aa)
RPS6KA2Ribosomal protein S6 kinase. (733 aa)
ENSVURP00010013724annotation not available (305 aa)
ENSVURP00010013703Uncharacterized protein. (1090 aa)
KIDINS220ANK_REP_REGION domain-containing protein. (1752 aa)
ID2BHLH domain-containing protein. (134 aa)
ENSVURP00010013014Uncharacterized protein. (77 aa)
LOC114027938GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (305 aa)
FNBP4Uncharacterized protein. (1047 aa)
NRASUncharacterized protein. (189 aa)
CSDE1Uncharacterized protein. (847 aa)
PCSK6Uncharacterized protein; Belongs to the peptidase S8 family. (911 aa)
ENSVURP00010012020BZIP domain-containing protein. (114 aa)
EGR1Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (559 aa)
PPP2R1AUncharacterized protein. (589 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1052 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
NGFNerve growth factor; Belongs to the NGF-beta family. (296 aa)
NTRK3Tyrosine-protein kinase receptor. (850 aa)
PPP2CASerine/threonine-protein phosphatase. (309 aa)
ATF1Uncharacterized protein. (313 aa)
RPS6KA1Ribosomal protein S6 kinase. (753 aa)
ENSVURP00010008520PID domain-containing protein. (342 aa)
FURINP/Homo B domain-containing protein; Belongs to the peptidase S8 family. (780 aa)
SHC4Uncharacterized protein. (345 aa)
SRFMADS-box domain-containing protein. (508 aa)
MAPK7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (807 aa)
ENSVURP00010007321Uncharacterized protein. (59 aa)
FRS2IRS-type PTB domain-containing protein. (508 aa)
AP2A2AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (862 aa)
HRASUncharacterized protein. (189 aa)
CREB1Uncharacterized protein. (327 aa)
RPS6KA4Ribosomal protein S6 kinase. (778 aa)
SGK1Non-specific serine/threonine protein kinase. (525 aa)
ENSVURP00010004670BAR domain-containing protein. (221 aa)
DNAL4Dynein light chain. (104 aa)
MAPK11Mitogen-activated protein kinase. (362 aa)
ID4BHLH domain-containing protein. (163 aa)
SOS1Uncharacterized protein. (1332 aa)
YWHAB14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (263 aa)
FOSL1BZIP domain-containing protein. (311 aa)
ENSVURP00010001268SH2 domain-containing protein. (100 aa)
BDNFBrain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. (254 aa)
ENSVURP00010000873Uncharacterized protein. (593 aa)
EGR4Uncharacterized protein. (486 aa)
NKPD1KAP NTPase domain-containing protein. (800 aa)
EGR2Uncharacterized protein. (475 aa)
Your Current Organism:
Vombatus ursinus
NCBI taxonomy Id: 29139
Other names: V. ursinus, coarse-haired wombat, common wombat
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