105 items (Vombatus ursinus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CCNQ	Cyclin Q; Belongs to the cyclin family. (247 aa)
	ITGB6	Integrin beta; Belongs to the integrin beta chain family. (788 aa)
	MAPK1	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (349 aa)
	ENSVURP00010029464	SKIP_SNW domain-containing protein. (531 aa)
	TGFBR2	TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (565 aa)
	ENSVURP00010029723	TGF_BETA_2 domain-containing protein. (264 aa)
	ENSVURP00010029726	annotation not available (264 aa)
	NEDD8	Ubiquitin-like domain-containing protein. (81 aa)
	MEIS3	Meis homeobox 3. (464 aa)
	ENSVURP00010030097	annotation not available (247 aa)
	ITGA8	Integrin subunit alpha 8; Belongs to the integrin alpha chain family. (1061 aa)
	ENSVURP00010030572	Uncharacterized protein. (89 aa)
	ENSVURP00010030573	annotation not available (89 aa)
	SKI	SKI proto-oncogene. (741 aa)
	ENSVURP00010031285	Par3_HAL_N_term domain-containing protein. (61 aa)
	LTBP4	Uncharacterized protein. (1585 aa)
	ENSVURP00010031290	PDZ domain-containing protein. (179 aa)
	ITGB1	Integrin beta; Belongs to the integrin beta chain family. (799 aa)
	BAMBI	BMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. (260 aa)
	MKX	Homeobox domain-containing protein. (353 aa)
	ENSVURP00010001782	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (188 aa)
	SMAD4	Mothers against decapentaplegic homolog. (552 aa)
	ARHGEF18	Uncharacterized protein. (1465 aa)
	LOC114046348	Transcription factor. (411 aa)
	NCOR2	Nuclear receptor corepressor 2. (2430 aa)
	SMAD7	Mothers against decapentaplegic homolog. (434 aa)
	SMAD2	Mothers against decapentaplegic homolog. (467 aa)
	ENSVURP00010028318	annotation not available (341 aa)
	E2F4	E2F_TDP domain-containing protein. (398 aa)
	IRX4	Homeobox domain-containing protein. (510 aa)
	IRX2	Homeobox domain-containing protein. (466 aa)
	IRX1	Homeobox domain-containing protein. (468 aa)
	PARD6A	Uncharacterized protein. (354 aa)
	ENSVURP00010027508	annotation not available (693 aa)
	CDK8	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (464 aa)
	IRX3	Homeobox domain-containing protein. (523 aa)
	IRX5	Homeobox domain-containing protein. (470 aa)
	IRX6	Homeobox domain-containing protein. (463 aa)
	F11R	Uncharacterized protein. (297 aa)
	LDLRAD4	Uncharacterized protein. (292 aa)
	LTBP1	Uncharacterized protein. (1705 aa)
	TGIF2	Homeobox domain-containing protein. (270 aa)
	ENSVURP00010024409	annotation not available (1164 aa)
	RNF111	RING-type domain-containing protein. (997 aa)
	PMEPA1	Uncharacterized protein. (286 aa)
	ZFYVE9	Zinc finger FYVE domain-containing protein. (1418 aa)
	LTBP2	Latent transforming growth factor beta binding protein 2. (1715 aa)
	SMURF1	E3 ubiquitin-protein ligase. (730 aa)
	PPM1A	Protein phosphatase, Mg2+/Mn2+ dependent 1A. (303 aa)
	ENSVURP00010023623	Ubiquitin-like domain-containing protein. (118 aa)
	ITGAV	Integrin_alpha2 domain-containing protein; Belongs to the integrin alpha chain family. (1063 aa)
	ENSVURP00010023509	Ubiquitin-like domain-containing protein. (84 aa)
	ENSVURP00010023486	E2F_TDP domain-containing protein. (341 aa)
	SMAD3	Mothers against decapentaplegic homolog. (426 aa)
	ENSVURP00010022789	Ubiquitin-like domain-containing protein. (156 aa)
	STRAP	WD_REPEATS_REGION domain-containing protein. (350 aa)
	ENSVURP00010022363	annotation not available (408 aa)
	PCSK4	P/Homo B domain-containing protein; Belongs to the peptidase S8 family. (773 aa)
	ENSVURP00010021762	annotation not available (509 aa)
	ENSVURP00010021329	TGFb_propeptide domain-containing protein. (131 aa)
	ENSVURP00010021103	annotation not available (1012 aa)
	CDK9	Cyclin dependent kinase 9; Belongs to the protein kinase superfamily. (373 aa)
	STUB1	Uncharacterized protein. (313 aa)
	SMURF2	E3 ubiquitin-protein ligase. (748 aa)
	UBA52	Ubiquitin-like domain-containing protein. (128 aa)
	ENSVURP00010019848	SKIP_SNW domain-containing protein. (501 aa)
	KXD1	KxDL domain-containing protein. (173 aa)
	ATP1B4	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (324 aa)
	ENSVURP00010018698	Myosin_tail_1 domain-containing protein. (1164 aa)
	RPS27A	Ubiquitin-like domain-containing protein. (156 aa)
	RBL1	Uncharacterized protein. (1065 aa)
	SKIL	c-SKI_SMAD_bind domain-containing protein. (690 aa)
	MTMR4	Uncharacterized protein. (1215 aa)
	UBE2M	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (183 aa)
	JUNB	BZIP domain-containing protein. (360 aa)
	CDK19	Protein kinase domain-containing protein. (487 aa)
	LOC114031682	Homeobox domain-containing protein. (247 aa)
	SP1	Sp1 transcription factor. (779 aa)
	ENSVURP00010013848	Ubiquitin-like domain-containing protein. (127 aa)
	ENSVURP00010013826	PP1c_bdg domain-containing protein. (447 aa)
	TGFB2	Transforming growth factor beta; Belongs to the TGF-beta family. (408 aa)
	TFDP2	Transcription factor. (420 aa)
	ENSVURP00010012149	Integrin beta; Belongs to the integrin beta chain family. (761 aa)
	LOC114049733	Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1012 aa)
	MAPK3	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
	CCNT2	Uncharacterized protein; Belongs to the cyclin family. (667 aa)
	TRIM33	Uncharacterized protein. (1139 aa)
	CCNC	Uncharacterized protein; Belongs to the cyclin family. (283 aa)
	ITGB5	Integrin beta; Belongs to the integrin beta chain family. (800 aa)
	NCOR1	Nuclear receptor corepressor 1. (2462 aa)
	FURIN	P/Homo B domain-containing protein; Belongs to the peptidase S8 family. (780 aa)
	ENSVURP00010007983	annotation not available (411 aa)
	CCNT1	CYCLIN domain-containing protein; Belongs to the cyclin family. (719 aa)
	LOC114038877	Ubiquitin-like domain-containing protein. (128 aa)
	FBN1	Uncharacterized protein. (2872 aa)
	PARD3B	Uncharacterized protein. (1204 aa)
	ENSVURP00010005410	Integrin beta; Belongs to the integrin beta chain family. (693 aa)
	NEDD4L	Uncharacterized protein. (975 aa)
	CBL	Uncharacterized protein. (916 aa)
	TGFB1	Transforming growth factor beta; Belongs to the TGF-beta family. (382 aa)
	MEN1	Uncharacterized protein. (633 aa)
	CCNK	Cyclin K; Belongs to the cyclin family. (572 aa)
	USP9X	USP domain-containing protein; Belongs to the peptidase C19 family. (2324 aa)
	LTBP3	Uncharacterized protein. (1287 aa)
	ENSVURP00010002081	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)

Your Current Organism:

Vombatus ursinus

NCBI taxonomy Id: 29139
Other names: V. ursinus, coarse-haired wombat, common wombat

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARHGEF18	ENSVURP00010002081	ENSVURP00010001314	ENSVURP00010002081	Uncharacterized protein.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.598
ARHGEF18	ENSVURP00010018698	ENSVURP00010001314	ENSVURP00010018698	Uncharacterized protein.	Myosin_tail_1 domain-containing protein.	0.862
ARHGEF18	ENSVURP00010021762	ENSVURP00010001314	ENSVURP00010021762	Uncharacterized protein.	annotation not available	0.598
ARHGEF18	ENSVURP00010022789	ENSVURP00010001314	ENSVURP00010022789	Uncharacterized protein.	Ubiquitin-like domain-containing protein.	0.574
ARHGEF18	ENSVURP00010023509	ENSVURP00010001314	ENSVURP00010023509	Uncharacterized protein.	Ubiquitin-like domain-containing protein.	0.574
ARHGEF18	ENSVURP00010023623	ENSVURP00010001314	ENSVURP00010023623	Uncharacterized protein.	Ubiquitin-like domain-containing protein.	0.574
ARHGEF18	ENSVURP00010024409	ENSVURP00010001314	ENSVURP00010024409	Uncharacterized protein.	annotation not available	0.862
ARHGEF18	ENSVURP00010031285	ENSVURP00010001314	ENSVURP00010031285	Uncharacterized protein.	Par3_HAL_N_term domain-containing protein.	0.698
ARHGEF18	ENSVURP00010031290	ENSVURP00010001314	ENSVURP00010031290	Uncharacterized protein.	PDZ domain-containing protein.	0.698
ARHGEF18	F11R	ENSVURP00010001314	ENSVURP00010025483	Uncharacterized protein.	Uncharacterized protein.	0.704
ARHGEF18	PARD3B	ENSVURP00010001314	ENSVURP00010006988	Uncharacterized protein.	Uncharacterized protein.	0.670
ARHGEF18	PARD6A	ENSVURP00010001314	ENSVURP00010028002	Uncharacterized protein.	Uncharacterized protein.	0.624
ARHGEF18	RPS27A	ENSVURP00010001314	ENSVURP00010018583	Uncharacterized protein.	Ubiquitin-like domain-containing protein.	0.574
ARHGEF18	SMURF1	ENSVURP00010001314	ENSVURP00010023785	Uncharacterized protein.	E3 ubiquitin-protein ligase.	0.642
ARHGEF18	SMURF2	ENSVURP00010001314	ENSVURP00010020184	Uncharacterized protein.	E3 ubiquitin-protein ligase.	0.615
ARHGEF18	TGFBR2	ENSVURP00010001314	ENSVURP00010029486	Uncharacterized protein.	TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...]	0.667
ATP1B4	ENSVURP00010019848	ENSVURP00010019619	ENSVURP00010019848	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	SKIP_SNW domain-containing protein.	0.775
ATP1B4	ENSVURP00010029464	ENSVURP00010019619	ENSVURP00010029464	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	SKIP_SNW domain-containing protein.	0.775
ATP1B4	SMAD7	ENSVURP00010019619	ENSVURP00010000374	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	Mothers against decapentaplegic homolog.	0.646
BAMBI	ENSVURP00010002081	ENSVURP00010031880	ENSVURP00010002081	BMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.932