STRINGSTRING
NRAS NRAS HRAS HRAS AP2A2 AP2A2 FRS2 FRS2 ENSVURP00010007321 ENSVURP00010007321 MAPK7 MAPK7 SRF SRF SHC4 SHC4 ENSVURP00010008520 ENSVURP00010008520 RPS6KA1 RPS6KA1 ATF1 ATF1 PPP2CA PPP2CA NGF NGF MAPK3 MAPK3 PIK3CB PIK3CB PPP2R1A PPP2R1A EGR1 EGR1 ENSVURP00010012020 ENSVURP00010012020 CSDE1 CSDE1 FNBP4 FNBP4 LOC114027938 LOC114027938 ENSVURP00010013014 ENSVURP00010013014 ID2 ID2 KIDINS220 KIDINS220 ENSVURP00010013724 ENSVURP00010013724 RPS6KA2 RPS6KA2 LOC114030907 LOC114030907 CLTA CLTA RALB RALB ENSVURP00010015187 ENSVURP00010015187 ENSVURP00010015196 ENSVURP00010015196 ENSVURP00010015212 ENSVURP00010015212 RPS6KA3 RPS6KA3 GRB2 GRB2 PPP2CB PPP2CB ENSVURP00010015742 ENSVURP00010015742 RALGDS RALGDS MAPKAPK2 MAPKAPK2 LOC114043375 LOC114043375 JUNB JUNB RAPGEF1 RAPGEF1 CLTC CLTC PIK3CA PIK3CA LYL1 LYL1 RALA RALA ENSVURP00010017057 ENSVURP00010017057 LOC114031856 LOC114031856 RPS6KA5 RPS6KA5 ENSVURP00010017741 ENSVURP00010017741 NTRK1 NTRK1 AP2A1 AP2A1 BRAF BRAF RIT1 RIT1 PIK3R2 PIK3R2 EGR3 EGR3 JUND JUND KRAS KRAS CLTCL1 CLTCL1 DUSP6 DUSP6 ENSVURP00010020577 ENSVURP00010020577 ENSVURP00010020687 ENSVURP00010020687 DUSP7 DUSP7 MAP2K1 MAP2K1 NAB1 NAB1 MAP2K5 MAP2K5 MAPKAPK3 MAPKAPK3 LOC114034866 LOC114034866 ARC ARC MAPK14 MAPK14 PIK3R1 PIK3R1 PPP2R1B PPP2R1B RELCH RELCH PPP4R4 PPP4R4 DUSP3 DUSP3 CRKL CRKL MAPK1 MAPK1 ENSVURP00010028896 ENSVURP00010028896 ENSVURP00010029009 ENSVURP00010029009 ENSVURP00010029292 ENSVURP00010029292 ENSVURP00010029610 ENSVURP00010029610 AP2M1 AP2M1 ID3 ID3 NAB2 NAB2 TRIB2 TRIB2 CREM CREM ASCL1 ASCL1 ENSVURP00010032211 ENSVURP00010032211 MAP2K2 MAP2K2 MAPK15 MAPK15 EGR2 EGR2 NKPD1 NKPD1 EGR4 EGR4 ENSVURP00010000873 ENSVURP00010000873 ENSVURP00010001268 ENSVURP00010001268 FOSL1 FOSL1 CHD4 CHD4 YWHAB YWHAB SOS1 SOS1 ID4 ID4 MAPK11 MAPK11 DNAL4 DNAL4 ENSVURP00010004670 ENSVURP00010004670 SGK1 SGK1 RPS6KA4 RPS6KA4 CREB1 CREB1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NRASUncharacterized protein. (189 aa)
HRASUncharacterized protein. (189 aa)
AP2A2AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (862 aa)
FRS2IRS-type PTB domain-containing protein. (508 aa)
ENSVURP00010007321Uncharacterized protein. (59 aa)
MAPK7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (807 aa)
SRFMADS-box domain-containing protein. (508 aa)
SHC4Uncharacterized protein. (345 aa)
ENSVURP00010008520PID domain-containing protein. (342 aa)
RPS6KA1Ribosomal protein S6 kinase. (753 aa)
ATF1Uncharacterized protein. (313 aa)
PPP2CASerine/threonine-protein phosphatase. (309 aa)
NGFNerve growth factor; Belongs to the NGF-beta family. (296 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1052 aa)
PPP2R1AUncharacterized protein. (589 aa)
EGR1Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (559 aa)
ENSVURP00010012020BZIP domain-containing protein. (114 aa)
CSDE1Uncharacterized protein. (847 aa)
FNBP4Uncharacterized protein. (1047 aa)
LOC114027938GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (305 aa)
ENSVURP00010013014Uncharacterized protein. (77 aa)
ID2BHLH domain-containing protein. (134 aa)
KIDINS220ANK_REP_REGION domain-containing protein. (1752 aa)
ENSVURP00010013724annotation not available (305 aa)
RPS6KA2Ribosomal protein S6 kinase. (733 aa)
LOC114030907AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (142 aa)
CLTAClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (223 aa)
RALBUncharacterized protein. (206 aa)
ENSVURP00010015187SH2 domain-containing protein. (98 aa)
ENSVURP00010015196PID domain-containing protein. (300 aa)
ENSVURP00010015212Protein kinase domain-containing protein. (364 aa)
RPS6KA3Ribosomal protein S6 kinase. (740 aa)
GRB2Uncharacterized protein. (217 aa)
PPP2CBSerine/threonine-protein phosphatase. (309 aa)
ENSVURP00010015742BHLH domain-containing protein. (241 aa)
RALGDSUncharacterized protein. (827 aa)
MAPKAPK2Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (422 aa)
LOC114043375AP complex subunit beta. (951 aa)
JUNBBZIP domain-containing protein. (360 aa)
RAPGEF1Uncharacterized protein. (1124 aa)
CLTCClathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1679 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
LYL1LYL1 basic helix-loop-helix family member. (308 aa)
RALAUncharacterized protein. (206 aa)
ENSVURP00010017057ETS domain-containing protein. (95 aa)
LOC114031856WRNPLPNID domain-containing protein. (956 aa)
RPS6KA5Ribosomal protein S6 kinase. (799 aa)
ENSVURP00010017741Protein kinase domain-containing protein. (369 aa)
NTRK1Tyrosine-protein kinase receptor. (743 aa)
AP2A1AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (973 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (741 aa)
RIT1Ras like without CAAX 1. (228 aa)
PIK3R2Uncharacterized protein. (738 aa)
EGR3Uncharacterized protein. (386 aa)
JUNDJunD proto-oncogene, AP-1 transcription factor subunit. (307 aa)
KRASUncharacterized protein. (189 aa)
CLTCL1Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1672 aa)
DUSP6Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (382 aa)
ENSVURP00010020577annotation not available (951 aa)
ENSVURP00010020687Uncharacterized protein. (578 aa)
DUSP7Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (378 aa)
MAP2K1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (393 aa)
NAB1Uncharacterized protein. (498 aa)
MAP2K5Uncharacterized protein; Belongs to the protein kinase superfamily. (448 aa)
MAPKAPK3Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (395 aa)
LOC114034866WRNPLPNID domain-containing protein. (943 aa)
ARCArc_C domain-containing protein. (400 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
PIK3R1Uncharacterized protein. (725 aa)
PPP2R1BUncharacterized protein. (662 aa)
RELCHRAB11 binding and LisH domain, coiled-coil and HEAT repeat containing. (1212 aa)
PPP4R4Uncharacterized protein. (871 aa)
DUSP3Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (182 aa)
CRKLUncharacterized protein. (303 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (349 aa)
ENSVURP00010028896Uncharacterized protein. (109 aa)
ENSVURP00010029009Uncharacterized protein. (566 aa)
ENSVURP00010029292annotation not available (956 aa)
ENSVURP00010029610annotation not available (142 aa)
AP2M1MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family. (437 aa)
ID3BHLH domain-containing protein. (118 aa)
NAB2Uncharacterized protein. (519 aa)
TRIB2Protein kinase domain-containing protein. (343 aa)
CREMUncharacterized protein. (332 aa)
ASCL1BHLH domain-containing protein. (249 aa)
ENSVURP00010032211Serine/threonine-protein phosphatase. (309 aa)
MAP2K2Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (400 aa)
MAPK15Mitogen-activated protein kinase 15. (545 aa)
EGR2Uncharacterized protein. (475 aa)
NKPD1KAP NTPase domain-containing protein. (800 aa)
EGR4Uncharacterized protein. (486 aa)
ENSVURP00010000873Uncharacterized protein. (593 aa)
ENSVURP00010001268SH2 domain-containing protein. (100 aa)
FOSL1BZIP domain-containing protein. (311 aa)
CHD4Uncharacterized protein. (1938 aa)
YWHAB14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (263 aa)
SOS1Uncharacterized protein. (1332 aa)
ID4BHLH domain-containing protein. (163 aa)
MAPK11Mitogen-activated protein kinase. (362 aa)
DNAL4Dynein light chain. (104 aa)
ENSVURP00010004670BAR domain-containing protein. (221 aa)
SGK1Non-specific serine/threonine protein kinase. (525 aa)
RPS6KA4Ribosomal protein S6 kinase. (778 aa)
CREB1Uncharacterized protein. (327 aa)
Your Current Organism:
Vombatus ursinus
NCBI taxonomy Id: 29139
Other names: V. ursinus, coarse-haired wombat, common wombat
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