STRINGSTRING
MAPK1 MAPK1 PTBP1 PTBP1 FGF22 FGF22 FGF10 FGF10 PTBP2 PTBP2 FGF18 FGF18 FGFR4 FGFR4 POLR2G POLR2G FGFBP1 FGFBP1 SOS1 SOS1 FGF8 FGF8 POLR2A POLR2A POLR2J POLR2J LOC114034826 LOC114034826 CBL CBL POLR2F POLR2F PTPN11 PTPN11 FGF7 FGF7 RBFOX2 RBFOX2 HRAS HRAS FGF20 FGF20 POLR2L POLR2L FLRT1 FLRT1 FGF16 FGF16 FRS2 FRS2 PTBP3 PTBP3 LOC114038877 LOC114038877 ENSVURP00010008705 ENSVURP00010008705 POLR2K POLR2K ENSVURP00010009261 ENSVURP00010009261 FLRT3 FLRT3 PPP2CA PPP2CA FGF6 FGF6 FGF23 FGF23 FGF17 FGF17 SPRY2 SPRY2 ENSVURP00010010877 ENSVURP00010010877 ENSVURP00010010882 ENSVURP00010010882 FRS3 FRS3 SPRED1 SPRED1 MAPK3 MAPK3 FGF1 FGF1 GTF2F2 GTF2F2 CSDE1 CSDE1 NRAS NRAS FGFR1 FGFR1 GAB1 GAB1 ENSVURP00010013703 ENSVURP00010013703 LOC114026793 LOC114026793 ENSVURP00010013848 ENSVURP00010013848 FGF5 FGF5 POLR2B POLR2B ENSVURP00010014975 ENSVURP00010014975 GRB2 GRB2 TIA1 TIA1 NCBP1 NCBP1 PPP2CB PPP2CB POLR2D POLR2D PIK3CA PIK3CA FNDC3B FNDC3B SPRED2 SPRED2 PLCG1 PLCG1 RPS27A RPS27A ENSVURP00010018775 ENSVURP00010018775 FLRT2 FLRT2 BRAF BRAF FGF2 FGF2 UBA52 UBA52 KRAS KRAS MKNK2 MKNK2 POLR2E POLR2E POLR2C POLR2C MKNK1 MKNK1 ENSVURP00010022789 ENSVURP00010022789 NCBP2 NCBP2 STIL STIL FGFR2 FGFR2 LOC114031469 LOC114031469 ESRP1 ESRP1 ENSVURP00010023509 ENSVURP00010023509 ENSVURP00010023623 ENSVURP00010023623 ENSVURP00010024728 ENSVURP00010024728 PIK3R1 PIK3R1 FGFRL1 FGFRL1 FGFR3 FGFR3 ESRP2 ESRP2 GALNT3 GALNT3 FGF9 FGF9 ANOS1 ANOS1 POLR2H POLR2H FNDC3A FNDC3A POLR2I POLR2I LOC114038227 LOC114038227 ENSVURP00010031918 ENSVURP00010031918 ENSVURP00010031927 ENSVURP00010031927 FGF3 FGF3 FGF4 FGF4 FGF19 FGF19 ENSVURP00010032211 ENSVURP00010032211 HNRNPM HNRNPM TIAL1 TIAL1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (349 aa)
PTBP1Uncharacterized protein. (557 aa)
FGF22Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (186 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (215 aa)
PTBP2Uncharacterized protein. (511 aa)
FGF18Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
FGFR4Fibroblast growth factor receptor. (849 aa)
POLR2GS1 domain-containing protein. (172 aa)
FGFBP1Uncharacterized protein. (231 aa)
SOS1Uncharacterized protein. (1332 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (214 aa)
POLR2ADNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1907 aa)
POLR2JRNA_pol_L_2 domain-containing protein. (117 aa)
LOC114034826Uncharacterized protein. (67 aa)
CBLUncharacterized protein. (916 aa)
POLR2FUncharacterized protein. (127 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
FGF7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
RBFOX2RNA binding protein fox-1 homolog; RNA-binding protein that regulates alternative splicing events. (378 aa)
HRASUncharacterized protein. (189 aa)
FGF20Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa)
POLR2LUncharacterized protein. (67 aa)
FLRT1Fibronectin type-III domain-containing protein. (676 aa)
FGF16Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
FRS2IRS-type PTB domain-containing protein. (508 aa)
PTBP3Polypyrimidine tract binding protein 3. (579 aa)
LOC114038877Ubiquitin-like domain-containing protein. (128 aa)
ENSVURP00010008705RRM domain-containing protein. (113 aa)
POLR2KUncharacterized protein. (64 aa)
ENSVURP00010009261Uncharacterized protein. (113 aa)
FLRT3Fibronectin type-III domain-containing protein. (649 aa)
PPP2CASerine/threonine-protein phosphatase. (309 aa)
FGF6Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (209 aa)
FGF23Uncharacterized protein; Belongs to the heparin-binding growth factors family. (245 aa)
FGF17Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (217 aa)
SPRY2Uncharacterized protein. (316 aa)
ENSVURP00010010877Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (513 aa)
ENSVURP00010010882Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (513 aa)
FRS3IRS-type PTB domain-containing protein. (508 aa)
SPRED1Uncharacterized protein. (448 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
GTF2F2General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (249 aa)
CSDE1Uncharacterized protein. (847 aa)
NRASUncharacterized protein. (189 aa)
FGFR1Fibroblast growth factor receptor. (822 aa)
GAB1PH domain-containing protein. (724 aa)
ENSVURP00010013703Uncharacterized protein. (1090 aa)
LOC114026793RNA_pol_L_2 domain-containing protein. (104 aa)
ENSVURP00010013848Ubiquitin-like domain-containing protein. (127 aa)
FGF5Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (273 aa)
POLR2BDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1174 aa)
ENSVURP00010014975TFIIF_beta domain-containing protein. (125 aa)
GRB2Uncharacterized protein. (217 aa)
TIA1Uncharacterized protein. (395 aa)
NCBP1MIF4G domain-containing protein. (794 aa)
PPP2CBSerine/threonine-protein phosphatase. (309 aa)
POLR2DRPOL4c domain-containing protein. (142 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
FNDC3BUncharacterized protein. (1211 aa)
SPRED2Uncharacterized protein. (419 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1279 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
ENSVURP00010018775RPOL4c domain-containing protein. (167 aa)
FLRT2Fibronectin type-III domain-containing protein. (661 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (741 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (156 aa)
UBA52Ubiquitin-like domain-containing protein. (128 aa)
KRASUncharacterized protein. (189 aa)
MKNK2Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (470 aa)
POLR2EUncharacterized protein. (210 aa)
POLR2CRPOLD domain-containing protein. (275 aa)
MKNK1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (431 aa)
ENSVURP00010022789Ubiquitin-like domain-containing protein. (156 aa)
NCBP2Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (157 aa)
STILUncharacterized protein. (1312 aa)
FGFR2Fibroblast growth factor receptor. (840 aa)
LOC114031469Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (156 aa)
ESRP1Uncharacterized protein. (675 aa)
ENSVURP00010023509Ubiquitin-like domain-containing protein. (84 aa)
ENSVURP00010023623Ubiquitin-like domain-containing protein. (118 aa)
ENSVURP00010024728annotation not available (156 aa)
PIK3R1Uncharacterized protein. (725 aa)
FGFRL1Uncharacterized protein. (495 aa)
FGFR3Fibroblast growth factor receptor. (851 aa)
ESRP2RRM domain-containing protein. (748 aa)
GALNT3Ricin B-type lectin domain-containing protein. (353 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (209 aa)
ANOS1Uncharacterized protein. (681 aa)
POLR2HDNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (150 aa)
FNDC3AUncharacterized protein. (1204 aa)
POLR2IDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (125 aa)
LOC114038227Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (643 aa)
ENSVURP00010031918Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (279 aa)
ENSVURP00010031927Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (477 aa)
FGF3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (274 aa)
FGF4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (205 aa)
FGF19Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (220 aa)
ENSVURP00010032211Serine/threonine-protein phosphatase. (309 aa)
HNRNPMHeterogeneous nuclear ribonucleoprotein M. (693 aa)
TIAL1Uncharacterized protein. (392 aa)
Your Current Organism:
Vombatus ursinus
NCBI taxonomy Id: 29139
Other names: V. ursinus, coarse-haired wombat, common wombat
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