36 items (Vombatus ursinus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSVURP00010013848	Ubiquitin-like domain-containing protein. (127 aa)
	LOC114038877	Ubiquitin-like domain-containing protein. (128 aa)
	PPP2CA	Serine/threonine-protein phosphatase. (309 aa)
	FGF6	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (209 aa)
	FGF23	Uncharacterized protein; Belongs to the heparin-binding growth factors family. (245 aa)
	FGF17	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (217 aa)
	SPRY2	Uncharacterized protein. (316 aa)
	MAPK3	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
	FGF1	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
	ENSVURP00010013703	Uncharacterized protein. (1090 aa)
	FGF5	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (273 aa)
	GRB2	Uncharacterized protein. (217 aa)
	PPP2CB	Serine/threonine-protein phosphatase. (309 aa)
	FNDC3B	Uncharacterized protein. (1211 aa)
	RPS27A	Ubiquitin-like domain-containing protein. (156 aa)
	BRAF	B-Raf proto-oncogene, serine/threonine kinase. (741 aa)
	FGF2	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (156 aa)
	UBA52	Ubiquitin-like domain-containing protein. (128 aa)
	MKNK2	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (470 aa)
	MKNK1	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (431 aa)
	ENSVURP00010022789	Ubiquitin-like domain-containing protein. (156 aa)
	ENSVURP00010023509	Ubiquitin-like domain-containing protein. (84 aa)
	ENSVURP00010023623	Ubiquitin-like domain-containing protein. (118 aa)
	MAPK1	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (349 aa)
	ANOS1	Uncharacterized protein. (681 aa)
	FNDC3A	Uncharacterized protein. (1204 aa)
	LOC114038227	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (643 aa)
	FGF3	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (274 aa)
	FGF4	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (205 aa)
	ENSVURP00010032211	Serine/threonine-protein phosphatase. (309 aa)
	FRS2	IRS-type PTB domain-containing protein. (508 aa)
	PTPN11	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
	CBL	Uncharacterized protein. (916 aa)
	FGF8	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (214 aa)
	FGF10	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (215 aa)
	FGF22	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (186 aa)

Your Current Organism:

Vombatus ursinus

NCBI taxonomy Id: 29139
Other names: V. ursinus, coarse-haired wombat, common wombat

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANOS1	FGF1	ENSVURP00010029175	ENSVURP00010011754	Uncharacterized protein.	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...]	0.783
ANOS1	FGF10	ENSVURP00010029175	ENSVURP00010000721	Uncharacterized protein.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.747
ANOS1	FGF17	ENSVURP00010029175	ENSVURP00010010192	Uncharacterized protein.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.753
ANOS1	FGF2	ENSVURP00010029175	ENSVURP00010019236	Uncharacterized protein.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.780
ANOS1	FGF22	ENSVURP00010029175	ENSVURP00010000094	Uncharacterized protein.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.747
ANOS1	FGF23	ENSVURP00010029175	ENSVURP00010009893	Uncharacterized protein.	Uncharacterized protein; Belongs to the heparin-binding growth factors family.	0.765
ANOS1	FGF3	ENSVURP00010029175	ENSVURP00010032197	Uncharacterized protein.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.659
ANOS1	FGF4	ENSVURP00010029175	ENSVURP00010032207	Uncharacterized protein.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.765
ANOS1	FGF5	ENSVURP00010029175	ENSVURP00010014413	Uncharacterized protein.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.722
ANOS1	FGF6	ENSVURP00010029175	ENSVURP00010009886	Uncharacterized protein.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.684
ANOS1	FGF8	ENSVURP00010029175	ENSVURP00010003187	Uncharacterized protein.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.868
BRAF	CBL	ENSVURP00010018833	ENSVURP00010004527	B-Raf proto-oncogene, serine/threonine kinase.	Uncharacterized protein.	0.530
BRAF	ENSVURP00010013848	ENSVURP00010018833	ENSVURP00010013848	B-Raf proto-oncogene, serine/threonine kinase.	Ubiquitin-like domain-containing protein.	0.579
BRAF	ENSVURP00010022789	ENSVURP00010018833	ENSVURP00010022789	B-Raf proto-oncogene, serine/threonine kinase.	Ubiquitin-like domain-containing protein.	0.408
BRAF	ENSVURP00010023509	ENSVURP00010018833	ENSVURP00010023509	B-Raf proto-oncogene, serine/threonine kinase.	Ubiquitin-like domain-containing protein.	0.408
BRAF	ENSVURP00010023623	ENSVURP00010018833	ENSVURP00010023623	B-Raf proto-oncogene, serine/threonine kinase.	Ubiquitin-like domain-containing protein.	0.408
BRAF	ENSVURP00010032211	ENSVURP00010018833	ENSVURP00010032211	B-Raf proto-oncogene, serine/threonine kinase.	Serine/threonine-protein phosphatase.	0.760
BRAF	FRS2	ENSVURP00010018833	ENSVURP00010007290	B-Raf proto-oncogene, serine/threonine kinase.	IRS-type PTB domain-containing protein.	0.448
BRAF	GRB2	ENSVURP00010018833	ENSVURP00010015476	B-Raf proto-oncogene, serine/threonine kinase.	Uncharacterized protein.	0.639
BRAF	LOC114038227	ENSVURP00010018833	ENSVURP00010030838	B-Raf proto-oncogene, serine/threonine kinase.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.554