STRINGSTRING
FGFR4 FGFR4 FGF18 FGF18 SOS1 SOS1 FGF8 FGF8 CBL CBL PTPN11 PTPN11 HRAS HRAS FGF20 FGF20 FGF16 FGF16 FRS2 FRS2 LOC114038877 LOC114038877 PPP2CA PPP2CA FGF6 FGF6 FGF23 FGF23 FGF17 FGF17 SPRY2 SPRY2 FRS3 FRS3 MAPK3 MAPK3 FGF1 FGF1 CSDE1 CSDE1 NRAS NRAS GAB1 GAB1 ENSVURP00010013703 ENSVURP00010013703 ENSVURP00010013848 ENSVURP00010013848 GRB2 GRB2 PPP2CB PPP2CB PIK3CA PIK3CA FNDC3B FNDC3B PLCG1 PLCG1 RPS27A RPS27A BRAF BRAF FGF2 FGF2 UBA52 UBA52 KRAS KRAS MKNK2 MKNK2 MKNK1 MKNK1 ENSVURP00010022789 ENSVURP00010022789 ENSVURP00010023509 ENSVURP00010023509 ENSVURP00010023623 ENSVURP00010023623 PIK3R1 PIK3R1 FGF9 FGF9 MAPK1 MAPK1 FNDC3A FNDC3A LOC114038227 LOC114038227 FGF4 FGF4 FGF19 FGF19 ENSVURP00010032211 ENSVURP00010032211
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FGFR4Fibroblast growth factor receptor. (849 aa)
FGF18Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
SOS1Uncharacterized protein. (1332 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (214 aa)
CBLUncharacterized protein. (916 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
HRASUncharacterized protein. (189 aa)
FGF20Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa)
FGF16Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
FRS2IRS-type PTB domain-containing protein. (508 aa)
LOC114038877Ubiquitin-like domain-containing protein. (128 aa)
PPP2CASerine/threonine-protein phosphatase. (309 aa)
FGF6Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (209 aa)
FGF23Uncharacterized protein; Belongs to the heparin-binding growth factors family. (245 aa)
FGF17Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (217 aa)
SPRY2Uncharacterized protein. (316 aa)
FRS3IRS-type PTB domain-containing protein. (508 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
CSDE1Uncharacterized protein. (847 aa)
NRASUncharacterized protein. (189 aa)
GAB1PH domain-containing protein. (724 aa)
ENSVURP00010013703Uncharacterized protein. (1090 aa)
ENSVURP00010013848Ubiquitin-like domain-containing protein. (127 aa)
GRB2Uncharacterized protein. (217 aa)
PPP2CBSerine/threonine-protein phosphatase. (309 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
FNDC3BUncharacterized protein. (1211 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1279 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (741 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (156 aa)
UBA52Ubiquitin-like domain-containing protein. (128 aa)
KRASUncharacterized protein. (189 aa)
MKNK2Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (470 aa)
MKNK1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (431 aa)
ENSVURP00010022789Ubiquitin-like domain-containing protein. (156 aa)
ENSVURP00010023509Ubiquitin-like domain-containing protein. (84 aa)
ENSVURP00010023623Ubiquitin-like domain-containing protein. (118 aa)
PIK3R1Uncharacterized protein. (725 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (209 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (349 aa)
FNDC3AUncharacterized protein. (1204 aa)
LOC114038227Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (643 aa)
FGF4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (205 aa)
FGF19Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (220 aa)
ENSVURP00010032211Serine/threonine-protein phosphatase. (309 aa)
Your Current Organism:
Vombatus ursinus
NCBI taxonomy Id: 29139
Other names: V. ursinus, coarse-haired wombat, common wombat
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