47 items (Vombatus ursinus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	FGF6	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (209 aa)
	FGF22	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (186 aa)
	FGF10	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (215 aa)
	INSR	Tyrosine-protein kinase receptor. (1374 aa)
	FGF18	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
	FGFR4	Fibroblast growth factor receptor. (849 aa)
	SOS1	Uncharacterized protein. (1332 aa)
	ENSVURP00010002802	Protein kinase domain-containing protein. (362 aa)
	LOC114043698	Protein kinase domain-containing protein. (683 aa)
	FGF8	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (214 aa)
	PTPN11	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
	FGF7	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
	FGF20	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa)
	FGF16	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
	ENSVURP00010007266	Phosphodiesterase. (858 aa)
	FRS2	IRS-type PTB domain-containing protein. (508 aa)
	FGF23	Uncharacterized protein; Belongs to the heparin-binding growth factors family. (245 aa)
	FGF17	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (217 aa)
	MAPK3	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
	PIK3CB	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1052 aa)
	FGF1	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
	FGFR1	Fibroblast growth factor receptor. (822 aa)
	GAB1	PH domain-containing protein. (724 aa)
	FGF5	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (273 aa)
	GRB2	Uncharacterized protein. (217 aa)
	INS	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (102 aa)
	PIK3CA	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	ENSVURP00010017524	Uncharacterized protein. (247 aa)
	ENSVURP00010018508	annotation not available (362 aa)
	FGF2	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (156 aa)
	PIK3R2	Uncharacterized protein. (738 aa)
	ENSVURP00010021023	annotation not available (683 aa)
	GAB2	PH domain-containing protein. (682 aa)
	TLR9	TIR domain-containing protein. (1041 aa)
	FGFR2	Fibroblast growth factor receptor. (840 aa)
	PIK3R1	Uncharacterized protein. (725 aa)
	FLT3	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (999 aa)
	FGFR3	Fibroblast growth factor receptor. (851 aa)
	FGF9	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (209 aa)
	MAPK1	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (349 aa)
	PIK3R4	Uncharacterized protein. (1363 aa)
	PIK3C3	Phosphatidylinositol 3-kinase catalytic subunit type 3. (887 aa)
	ENSVURP00010029153	Protein kinase domain-containing protein. (542 aa)
	LOC114038227	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (643 aa)
	FGF3	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (274 aa)
	FGF4	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (205 aa)
	FGF19	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (220 aa)

Your Current Organism:

Vombatus ursinus

NCBI taxonomy Id: 29139
Other names: V. ursinus, coarse-haired wombat, common wombat

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSVURP00010002802	ENSVURP00010021023	ENSVURP00010002802	ENSVURP00010021023	Protein kinase domain-containing protein.	annotation not available	0.648
ENSVURP00010002802	ENSVURP00010029153	ENSVURP00010002802	ENSVURP00010029153	Protein kinase domain-containing protein.	Protein kinase domain-containing protein.	0.648
ENSVURP00010002802	LOC114043698	ENSVURP00010002802	ENSVURP00010002963	Protein kinase domain-containing protein.	Protein kinase domain-containing protein.	0.648
ENSVURP00010002802	PIK3C3	ENSVURP00010002802	ENSVURP00010028867	Protein kinase domain-containing protein.	Phosphatidylinositol 3-kinase catalytic subunit type 3.	0.674
ENSVURP00010002802	PIK3R4	ENSVURP00010002802	ENSVURP00010028799	Protein kinase domain-containing protein.	Uncharacterized protein.	0.680
ENSVURP00010017524	FGF1	ENSVURP00010017524	ENSVURP00010011754	Uncharacterized protein.	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...]	0.491
ENSVURP00010017524	FGF17	ENSVURP00010017524	ENSVURP00010010192	Uncharacterized protein.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.475
ENSVURP00010017524	FGF18	ENSVURP00010017524	ENSVURP00010001715	Uncharacterized protein.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.475
ENSVURP00010017524	FGF19	ENSVURP00010017524	ENSVURP00010032209	Uncharacterized protein.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.458
ENSVURP00010017524	FGF2	ENSVURP00010017524	ENSVURP00010019236	Uncharacterized protein.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.703
ENSVURP00010017524	FGF23	ENSVURP00010017524	ENSVURP00010009893	Uncharacterized protein.	Uncharacterized protein; Belongs to the heparin-binding growth factors family.	0.458
ENSVURP00010017524	FGF3	ENSVURP00010017524	ENSVURP00010032197	Uncharacterized protein.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.475
ENSVURP00010017524	FGF4	ENSVURP00010017524	ENSVURP00010032207	Uncharacterized protein.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.491
ENSVURP00010017524	FGF5	ENSVURP00010017524	ENSVURP00010014413	Uncharacterized protein.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.476
ENSVURP00010017524	FGF6	ENSVURP00010017524	ENSVURP00010009886	Uncharacterized protein.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.488
ENSVURP00010017524	FGF7	ENSVURP00010017524	ENSVURP00010005385	Uncharacterized protein.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.491
ENSVURP00010017524	FGF8	ENSVURP00010017524	ENSVURP00010003187	Uncharacterized protein.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.416
ENSVURP00010017524	FGFR1	ENSVURP00010017524	ENSVURP00010013038	Uncharacterized protein.	Fibroblast growth factor receptor.	0.837
ENSVURP00010017524	FGFR2	ENSVURP00010017524	ENSVURP00010023022	Uncharacterized protein.	Fibroblast growth factor receptor.	0.837
ENSVURP00010017524	FGFR3	ENSVURP00010017524	ENSVURP00010027799	Uncharacterized protein.	Fibroblast growth factor receptor.	0.861