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ENSVURP00010028933 ENSVURP00010028933 ENSVURP00010029153 ENSVURP00010029153 IDE IDE ATP6V0B ATP6V0B PTPN1 PTPN1 ATP6AP1 ATP6AP1 NRDC NRDC FGFR2 FGFR2 TLR9 TLR9 GAB2 GAB2 ENSVURP00010006295 ENSVURP00010006295 FGF20 FGF20 ATP6V0D2 ATP6V0D2 FGF16 FGF16 ENSVURP00010007266 ENSVURP00010007266 FRS2 FRS2 ENSVURP00010007416 ENSVURP00010007416 ENSVURP00010007502 ENSVURP00010007502 ENSVURP00010009120 ENSVURP00010009120 ATP6V1C2 ATP6V1C2 ENSVURP00010021023 ENSVURP00010021023 ENSVURP00010020819 ENSVURP00010020819 PIK3R2 PIK3R2 ENSVURP00010019427 ENSVURP00010019427 FGF2 FGF2 ATP6V1A ATP6V1A ENSVURP00010018508 ENSVURP00010018508 ATP6V0A4 ATP6V0A4 ENSVURP00010017524 ENSVURP00010017524 PIK3CA PIK3CA ENSVURP00010016347 ENSVURP00010016347 INS INS GRB2 GRB2 ENSVURP00010014968 ENSVURP00010014968 ENSVURP00010014954 ENSVURP00010014954 FGF5 FGF5 GAB1 GAB1 FGFR1 FGFR1 FGF1 FGF1 PIK3CB PIK3CB LIM2 LIM2 MAPK3 MAPK3 LOC114050011 LOC114050011 ATP6V1B2 ATP6V1B2 FGF17 FGF17 ENSVURP00010009985 ENSVURP00010009985 FGF23 FGF23 FGF6 FGF6 ATP6V1C1 ATP6V1C1 ATP6V0E2 ATP6V0E2 ATP6V1G3 ATP6V1G3 LOC114027834 LOC114027834 ATP6V1F ATP6V1F FGF7 FGF7 PTPN11 PTPN11 LOC114047087 LOC114047087 ENSVURP00010003204 ENSVURP00010003204 FGF8 FGF8 LOC114043698 LOC114043698 ENSVURP00010002802 ENSVURP00010002802 ATP6V1G2 ATP6V1G2 SOS1 SOS1 FGFR4 FGFR4 FGF18 FGF18 ATP6V0A2 ATP6V0A2 ATP6V1D ATP6V1D LOC114038227 LOC114038227 ATP6V1E1 ATP6V1E1 FGF3 FGF3 FGF22 FGF22 FGF4 FGF4 FGF19 FGF19 TCIRG1 TCIRG1 PIK3R1 PIK3R1 LOC114031907 LOC114031907 INSR INSR ATP6V0E1 ATP6V0E1 FGF10 FGF10 FLT3 FLT3 ENSVURP00010026778 ENSVURP00010026778 ATP6V1B1 ATP6V1B1 FGFR3 FGFR3 FGF9 FGF9 ATP6V0D1 ATP6V0D1 ATP6V0A1 ATP6V0A1 MAPK1 MAPK1 PIK3R4 PIK3R4 PIK3C3 PIK3C3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSVURP00010028933Uncharacterized protein. (476 aa)
ENSVURP00010029153Protein kinase domain-containing protein. (542 aa)
IDEUncharacterized protein; Belongs to the peptidase M16 family. (1019 aa)
ATP6V0BUncharacterized protein; Belongs to the V-ATPase proteolipid subunit family. (205 aa)
PTPN1Tyrosine-protein phosphatase non-receptor type. (423 aa)
ATP6AP1Uncharacterized protein. (475 aa)
NRDCUncharacterized protein. (1216 aa)
FGFR2Fibroblast growth factor receptor. (840 aa)
TLR9TIR domain-containing protein. (1041 aa)
GAB2PH domain-containing protein. (682 aa)
ENSVURP00010006295Uncharacterized protein. (87 aa)
FGF20Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa)
ATP6V0D2V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family. (351 aa)
FGF16Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
ENSVURP00010007266Phosphodiesterase. (858 aa)
FRS2IRS-type PTB domain-containing protein. (508 aa)
ENSVURP00010007416V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (112 aa)
ENSVURP00010007502annotation not available (483 aa)
ENSVURP00010009120V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (250 aa)
ATP6V1C2V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (427 aa)
ENSVURP00010021023annotation not available (683 aa)
ENSVURP00010020819annotation not available (727 aa)
PIK3R2Uncharacterized protein. (738 aa)
ENSVURP00010019427annotation not available (118 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (156 aa)
ATP6V1AUncharacterized protein. (617 aa)
ENSVURP00010018508annotation not available (362 aa)
ATP6V0A4V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (838 aa)
ENSVURP00010017524Uncharacterized protein. (247 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
ENSVURP00010016347Uncharacterized protein. (74 aa)
INSInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (102 aa)
GRB2Uncharacterized protein. (217 aa)
ENSVURP00010014968Uncharacterized protein. (71 aa)
ENSVURP00010014954V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (112 aa)
FGF5Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (273 aa)
GAB1PH domain-containing protein. (724 aa)
FGFR1Fibroblast growth factor receptor. (822 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1052 aa)
LIM2Lens fiber membrane intrinsic protein; Present in the thicker 16-17 nm junctions of mammalian lens fiber cells, where it may contribute to cell junctional organization. Acts as a receptor for calmodulin. May play an important role in both lens development and cataractogenesis; Belongs to the PMP-22/EMP/MP20 family. (173 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
LOC114050011Consortin_C domain-containing protein. (727 aa)
ATP6V1B2Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (512 aa)
FGF17Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (217 aa)
ENSVURP00010009985V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (90 aa)
FGF23Uncharacterized protein; Belongs to the heparin-binding growth factors family. (245 aa)
FGF6Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (209 aa)
ATP6V1C1V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (382 aa)
ATP6V0E2V-type proton ATPase subunit; Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (81 aa)
ATP6V1G3V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (119 aa)
LOC114027834V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (165 aa)
ATP6V1FV-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (119 aa)
FGF7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
LOC114047087V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (118 aa)
ENSVURP00010003204Uncharacterized protein. (109 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (214 aa)
LOC114043698Protein kinase domain-containing protein. (683 aa)
ENSVURP00010002802Protein kinase domain-containing protein. (362 aa)
ATP6V1G2V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (118 aa)
SOS1Uncharacterized protein. (1332 aa)
FGFR4Fibroblast growth factor receptor. (849 aa)
FGF18Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
ATP6V0A2V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (854 aa)
ATP6V1DUncharacterized protein. (247 aa)
LOC114038227Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (643 aa)
ATP6V1E1Uncharacterized protein. (226 aa)
FGF3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (274 aa)
FGF22Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (186 aa)
FGF4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (205 aa)
FGF19Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (220 aa)
TCIRG1V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (838 aa)
PIK3R1Uncharacterized protein. (725 aa)
LOC114031907V-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. (483 aa)
INSRTyrosine-protein kinase receptor. (1374 aa)
ATP6V0E1V-type proton ATPase subunit; Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (81 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (215 aa)
FLT3Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (999 aa)
ENSVURP00010026778V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (409 aa)
ATP6V1B1Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (524 aa)
FGFR3Fibroblast growth factor receptor. (851 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (209 aa)
ATP6V0D1V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family. (351 aa)
ATP6V0A1V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (838 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (349 aa)
PIK3R4Uncharacterized protein. (1363 aa)
PIK3C3Phosphatidylinositol 3-kinase catalytic subunit type 3. (887 aa)
Your Current Organism:
Vombatus ursinus
NCBI taxonomy Id: 29139
Other names: V. ursinus, coarse-haired wombat, common wombat
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