(136 nodes) CDC42 GTPase cycle network (Vombatus ursinus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SPATA13	Uncharacterized protein. (1270 aa)
	ARAP2	Uncharacterized protein. (1697 aa)
	ENSVURP00010009260	Calponin-homology (CH) domain-containing protein. (88 aa)
	DOCK8	Uncharacterized protein; Belongs to the DOCK family. (2102 aa)
	WDR81	Uncharacterized protein. (1908 aa)
	ABR	Uncharacterized protein. (1195 aa)
	ARHGDIA	Uncharacterized protein. (204 aa)
	ARHGEF10	DH domain-containing protein. (1355 aa)
	FAM13B	Rho-GAP domain-containing protein. (943 aa)
	FMN1	Formin 1. (1465 aa)
	ARHGAP27	Uncharacterized protein. (744 aa)
	ENSVURP00010011689	SH3 domain-containing protein. (281 aa)
	ARHGAP26	Rho GTPase activating protein 26. (723 aa)
	DOCK7	Uncharacterized protein; Belongs to the DOCK family. (2129 aa)
	LOC114050020	Tudor domain-containing protein. (612 aa)
	ARAP3	Uncharacterized protein. (1574 aa)
	CAV3	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (150 aa)
	MYO9B	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2176 aa)
	WAS	Uncharacterized protein. (494 aa)
	VAV2	Vav guanine nucleotide exchange factor 2. (758 aa)
	ARHGAP1	Uncharacterized protein. (439 aa)
	KCTD3	BTB domain-containing protein. (818 aa)
	SRGAP3	SLIT-ROBO Rho GTPase activating protein 3. (1093 aa)
	LOC114030927	Uncharacterized protein. (1499 aa)
	DOCK6	Dedicator of cytokinesis 6; Belongs to the DOCK family. (1953 aa)
	ARHGAP10	Uncharacterized protein. (785 aa)
	ENSVURP00010015377	Uncharacterized protein. (1020 aa)
	ARHGEF4	Uncharacterized protein. (2150 aa)
	SRGAP2	Uncharacterized protein. (1074 aa)
	LOC114040382	Uncharacterized protein. (140 aa)
	LOC114040382-2	Uncharacterized protein. (162 aa)
	GNA13	Uncharacterized protein. (377 aa)
	ECT2	Uncharacterized protein. (942 aa)
	ARHGAP42	Uncharacterized protein. (874 aa)
	ARHGEF19	Uncharacterized protein. (810 aa)
	LOC114031841	Rho-GAP domain-containing protein. (656 aa)
	KIAA1755	Uncharacterized protein. (1288 aa)
	ARHGAP40	Rho-GAP domain-containing protein. (713 aa)
	WDR91	Uncharacterized protein. (747 aa)
	ARHGEF11	Uncharacterized protein. (1555 aa)
	ARHGAP31	Rho-GAP domain-containing protein. (1462 aa)
	PIK3R2	Uncharacterized protein. (738 aa)
	ENSVURP00010019644	Uncharacterized protein. (1457 aa)
	ENSVURP00010019910	FH2 domain-containing protein. (1531 aa)
	ENSVURP00010019979	Uncharacterized protein. (143 aa)
	ARHGAP44	Uncharacterized protein. (801 aa)
	ENSVURP00010020703	Uncharacterized protein. (248 aa)
	VAV3	Uncharacterized protein. (873 aa)
	ARHGAP22	Uncharacterized protein. (771 aa)
	ENSVURP00010021336	Uncharacterized protein. (831 aa)
	ENSVURP00010021429	annotation not available (612 aa)
	DNMBP	Uncharacterized protein. (1598 aa)
	ARHGAP17	Rho GTPase activating protein 17. (809 aa)
	ENSVURP00010022332	BAR domain-containing protein. (71 aa)
	ARHGEF26	Uncharacterized protein. (877 aa)
	ARHGDIB	Uncharacterized protein. (200 aa)
	KTN1	Uncharacterized protein. (1348 aa)
	LOC114031401	Rho-GAP domain-containing protein. (692 aa)
	FGD3	Uncharacterized protein. (910 aa)
	ENSVURP00010024480	Uncharacterized protein. (198 aa)
	DEF6	PH domain-containing protein. (620 aa)
	ENSVURP00010024725	annotation not available (692 aa)
	ARHGAP30	Rho-GAP domain-containing protein. (1138 aa)
	PIK3R1	Uncharacterized protein. (725 aa)
	FGD2	Uncharacterized protein. (665 aa)
	LOC114028530	Uncharacterized protein. (143 aa)
	STARD13	Uncharacterized protein. (1126 aa)
	ARHGAP20	Uncharacterized protein. (1193 aa)
	FGD1	FYVE, RhoGEF and PH domain containing 1. (904 aa)
	CAV1	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
	BCR	BCR activator of RhoGEF and GTPase. (1236 aa)
	LOC114054096	Uncharacterized protein. (1606 aa)
	DEPDC1B	Uncharacterized protein. (725 aa)
	TRIO	Trio Rho guanine nucleotide exchange factor. (3036 aa)
	ENSVURP00010027642	Uncharacterized protein. (876 aa)
	ARHGAP4	Uncharacterized protein. (1010 aa)
	ENSVURP00010027947	Uncharacterized protein. (195 aa)
	ENSVURP00010028202	Uncharacterized protein. (1104 aa)
	PLEKHG4B	Uncharacterized protein. (1788 aa)
	ARHGAP32	Uncharacterized protein. (2020 aa)
	ENSVURP00010028575	Rib_recp_KP_reg domain-containing protein. (161 aa)
	ENSVURP00010028578	annotation not available (161 aa)
	ARHGAP24	Uncharacterized protein. (739 aa)
	ENSVURP00010029307	annotation not available (656 aa)
	NGEF	Uncharacterized protein. (699 aa)
	ENSVURP00010029622	annotation not available (1499 aa)
	ENSVURP00010029667	Uncharacterized protein. (394 aa)
	ARHGEF25	Uncharacterized protein. (609 aa)
	ENSVURP00010030135	Uncharacterized protein. (1578 aa)
	ENSVURP00010030137	Uncharacterized protein. (245 aa)
	ARHGAP9	Uncharacterized protein. (738 aa)
	ENSVURP00010030548	Uncharacterized protein. (536 aa)
	ARHGAP33	Rho GTPase activating protein 33. (1300 aa)
	PLEKHG3	Uncharacterized protein. (1373 aa)
	CDC42	Uncharacterized protein. (191 aa)
	ENSVURP00010031241	Uncharacterized protein. (719 aa)
	DOCK9	Dedicator of cytokinesis 9; Belongs to the DOCK family. (2205 aa)
	FARP1	Uncharacterized protein. (1042 aa)
	SRGAP1	Uncharacterized protein. (1087 aa)
	ENSVURP00010032019	annotation not available (696 aa)
	ARHGAP21	Rho GTPase activating protein 21. (1886 aa)
	SYDE1	Rho-GAP domain-containing protein. (751 aa)
	GMIP	GEM interacting protein. (929 aa)
	KALRN	Kalirin RhoGEF kinase. (2312 aa)
	DOCK10	Uncharacterized protein; Belongs to the DOCK family. (2200 aa)
	RACGAP1	Uncharacterized protein. (632 aa)
	ENSVURP00010009150	FH2 domain-containing protein. (1161 aa)
	ENSVURP00010009194	FH2 domain-containing protein. (198 aa)
	ENSVURP00010007505	annotation not available (1204 aa)
	CDC42SE2	CRIB domain-containing protein. (84 aa)
	WASHC1	WH2 domain-containing protein. (470 aa)
	WIPF2	WH2 domain-containing protein. (350 aa)
	STARD8	StAR related lipid transfer domain containing 8. (1027 aa)
	DLC1	Uncharacterized protein. (1514 aa)
	OPHN1	Uncharacterized protein. (801 aa)
	TIAM1	Uncharacterized protein. (1567 aa)
	FGD4	Uncharacterized protein. (888 aa)
	ITSN1	Uncharacterized protein. (1217 aa)
	ENSVURP00010005274	DH domain-containing protein. (257 aa)
	ARHGEF12	Uncharacterized protein. (1539 aa)
	ARHGAP39	Rho GTPase activating protein 39. (1046 aa)
	YKT6	Uncharacterized protein; Belongs to the synaptobrevin family. (198 aa)
	DOCK11	Uncharacterized protein; Belongs to the DOCK family. (1889 aa)
	ENSVURP00010002710	Uncharacterized protein. (1445 aa)
	ENSVURP00010002604	Uncharacterized protein. (1365 aa)
	ARHGAP5	Uncharacterized protein. (1505 aa)
	LOC114043905	Uncharacterized protein. (225 aa)
	PLEKHG1	Uncharacterized protein. (1496 aa)
	ENSVURP00010001865	Uncharacterized protein. (1211 aa)
	ENSVURP00010000837	Uncharacterized protein. (1508 aa)
	ENSVURP00010000811	Uncharacterized protein. (139 aa)
	LOC114031664	Uncharacterized protein. (1069 aa)
	SHKBP1	BTB domain-containing protein. (714 aa)
	ARHGEF9	Uncharacterized protein. (1173 aa)
	LOC114046234	Uncharacterized protein. (1204 aa)
	ENSVURP00010000016	Uncharacterized protein. (594 aa)

Your Current Organism:

Vombatus ursinus

NCBI taxonomy Id: 29139
Other names: V. ursinus, coarse-haired wombat, common wombat

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABR	ARHGAP1	ENSVURP00010011141	ENSVURP00010013569	Uncharacterized protein.	Uncharacterized protein.	0.734
ABR	ARHGAP27	ENSVURP00010011141	ENSVURP00010011672	Uncharacterized protein.	Uncharacterized protein.	0.682
ABR	ARHGAP9	ENSVURP00010011141	ENSVURP00010030276	Uncharacterized protein.	Uncharacterized protein.	0.682
ABR	ARHGEF11	ENSVURP00010011141	ENSVURP00010018101	Uncharacterized protein.	Uncharacterized protein.	0.492
ABR	ARHGEF12	ENSVURP00010011141	ENSVURP00010003941	Uncharacterized protein.	Uncharacterized protein.	0.492
ABR	ARHGEF4	ENSVURP00010011141	ENSVURP00010016216	Uncharacterized protein.	Uncharacterized protein.	0.432
ABR	ARHGEF9	ENSVURP00010011141	ENSVURP00010000346	Uncharacterized protein.	Uncharacterized protein.	0.432
ABR	CDC42	ENSVURP00010011141	ENSVURP00010030824	Uncharacterized protein.	Uncharacterized protein.	0.753
ABR	DEPDC1B	ENSVURP00010011141	ENSVURP00010027403	Uncharacterized protein.	Uncharacterized protein.	0.552
ABR	ENSVURP00010001865	ENSVURP00010011141	ENSVURP00010001865	Uncharacterized protein.	Uncharacterized protein.	0.721
ABR	ENSVURP00010009150	ENSVURP00010011141	ENSVURP00010009150	Uncharacterized protein.	FH2 domain-containing protein.	0.611
ABR	ENSVURP00010009194	ENSVURP00010011141	ENSVURP00010009194	Uncharacterized protein.	FH2 domain-containing protein.	0.611
ABR	ENSVURP00010011689	ENSVURP00010011141	ENSVURP00010011689	Uncharacterized protein.	SH3 domain-containing protein.	0.682
ABR	ENSVURP00010019910	ENSVURP00010011141	ENSVURP00010019910	Uncharacterized protein.	FH2 domain-containing protein.	0.611
ABR	ENSVURP00010027947	ENSVURP00010011141	ENSVURP00010027947	Uncharacterized protein.	Uncharacterized protein.	0.753
ABR	FMN1	ENSVURP00010011141	ENSVURP00010011657	Uncharacterized protein.	Formin 1.	0.611
ABR	GMIP	ENSVURP00010011141	ENSVURP00010032656	Uncharacterized protein.	GEM interacting protein.	0.721
ABR	LOC114031664	ENSVURP00010011141	ENSVURP00010000661	Uncharacterized protein.	Uncharacterized protein.	0.721
ABR	MYO9B	ENSVURP00010011141	ENSVURP00010013309	Uncharacterized protein.	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.814
ABR	PIK3R1	ENSVURP00010011141	ENSVURP00010025486	Uncharacterized protein.	Uncharacterized protein.	0.422