STRINGSTRING
PDK1 PDK1 PIK3R1 PIK3R1 SLC2A1 SLC2A1 CDKN1A CDKN1A ENSVURP00010024966 ENSVURP00010024966 ENSVURP00010024791 ENSVURP00010024791 LTBR LTBR HIF1A HIF1A ENSVURP00010023428 ENSVURP00010023428 ENSVURP00010022990 ENSVURP00010022990 CREBBP CREBBP MKNK1 MKNK1 MAP2K1 MAP2K1 LOC114024909 LOC114024909 PRKCB PRKCB ENSVURP00010022394 ENSVURP00010022394 PFKL PFKL ENSVURP00010022176 ENSVURP00010022176 LOC114053911 LOC114053911 ENSVURP00010021924 ENSVURP00010021924 LDHB LDHB PLCG2 PLCG2 LOC114049654 LOC114049654 LOC114049642-2 LOC114049642-2 MKNK2 MKNK2 LOC114047389-2 LOC114047389-2 ENSVURP00010020165 ENSVURP00010020165 ENSVURP00010019785 ENSVURP00010019785 PIK3R2 PIK3R2 ENSVURP00010019471 ENSVURP00010019471 ENSVURP00010019441 ENSVURP00010019441 PRKCA PRKCA ENSVURP00010019093 ENSVURP00010019093 HKDC1 HKDC1 HK1 HK1 ENSVURP00010018718 ENSVURP00010018718 ENSVURP00010018604 ENSVURP00010018604 GAPDH GAPDH PLCG1 PLCG1 EGFR EGFR ENSVURP00010017868 ENSVURP00010017868 CAMK2G CAMK2G ENSVURP00010017456 ENSVURP00010017456 TIMP1 TIMP1 BCL2 BCL2 PIK3CA PIK3CA RPS6KB1 RPS6KB1 PDHA1 PDHA1 INS INS HK2 HK2 ENSVURP00010015255 ENSVURP00010015255 ENSVURP00010015203 ENSVURP00010015203 VHL VHL PRKCG PRKCG LOC114045424 LOC114045424 ENSVURP00010014402 ENSVURP00010014402 ENSVURP00010014299 ENSVURP00010014299 ENSVURP00010014291 ENSVURP00010014291 ENSVURP00010014276 ENSVURP00010014276 NOS2 NOS2 ENSVURP00010013807 ENSVURP00010013807 ALDOC ALDOC EIF4EBP1 EIF4EBP1 ENSVURP00010013035 ENSVURP00010013035 LOC114052108 LOC114052108 ENSVURP00010011447 ENSVURP00010011447 RPS6KB2 RPS6KB2 MAP2K2 MAP2K2 ENSVURP00010031637 ENSVURP00010031637 LOC114029412 LOC114029412 IFNG IFNG PIK3CD PIK3CD MTOR MTOR NPPA NPPA IGF1 IGF1 CUL2 CUL2 EGLN2 EGLN2 ENSVURP00010031228 ENSVURP00010031228 PFKP PFKP ENSVURP00010030726 ENSVURP00010030726 ENSVURP00010030613 ENSVURP00010030613 ENSVURP00010030608 ENSVURP00010030608 ENSVURP00010030582 ENSVURP00010030582 ENSVURP00010030513 ENSVURP00010030513 ENSVURP00010030368 ENSVURP00010030368 ENSVURP00010029927 ENSVURP00010029927 EIF4E2 EIF4E2 ENSVURP00010029282 ENSVURP00010029282 ENSVURP00010029067 ENSVURP00010029067 ENSVURP00010028940 ENSVURP00010028940 ENSVURP00010028836 ENSVURP00010028836 STAT3 STAT3 MAPK1 MAPK1 ENSVURP00010028054 ENSVURP00010028054 ENSVURP00010028008 ENSVURP00010028008 PIK3CB PIK3CB ENSVURP00010011398 ENSVURP00010011398 ALDOA ALDOA IGF1R IGF1R MAPK3 MAPK3 ANGPT2 ANGPT2 ANGPT1 ANGPT1 CAMK2A CAMK2A LOC114037540 LOC114037540 ENSVURP00010010434 ENSVURP00010010434 ENSVURP00010010429 ENSVURP00010010429 ENSVURP00010010317 ENSVURP00010010317 ENSVURP00010010314 ENSVURP00010010314 TFRC TFRC LOC114049642 LOC114049642 NOS3 NOS3 ENSVURP00010009820 ENSVURP00010009820 CDKN1B CDKN1B LOC114037604 LOC114037604 ELOC ELOC ENSVURP00010008839 ENSVURP00010008839 TEK TEK PFKM PFKM CAMK2D CAMK2D ERBB2 ERBB2 PGK1 PGK1 AKT1 AKT1 EGF EGF VEGFA VEGFA HMOX1 HMOX1 LOC114047389 LOC114047389 PDHB PDHB IFNGR2 IFNGR2 IFNGR1 IFNGR1 EDN1 EDN1 ENSVURP00010003961 ENSVURP00010003961 ALDOB ALDOB ENSVURP00010003469 ENSVURP00010003469 ENSVURP00010003442 ENSVURP00010003442 EGLN3 EGLN3 CAMK2B CAMK2B LOC114050566 LOC114050566 RBX1 RBX1 ENSVURP00010002486 ENSVURP00010002486 EP300 EP300 ENO2 ENO2 EIF4E1B EIF4E1B EIF4E EIF4E RELA RELA HK3 HK3 ENO3 ENO3 CYBB CYBB ENSVURP00010001588 ENSVURP00010001588 ENSVURP00010001366 ENSVURP00010001366 LOC114031174 LOC114031174 INSR INSR ENSVURP00010001019 ENSVURP00010001019 EPO EPO ELOB ELOB ENSVURP00010000485 ENSVURP00010000485 LDHA LDHA ENSVURP00010000389 ENSVURP00010000389 LOC114042902 LOC114042902 LDHC LDHC ENSVURP00010000232 ENSVURP00010000232 ENSVURP00010000175 ENSVURP00010000175 LOC114034122 LOC114034122 NFKB1 NFKB1 FLT1 FLT1 ENSVURP00010026384 ENSVURP00010026384 AKT2 AKT2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PDK1Protein-serine/threonine kinase. (429 aa)
PIK3R1Uncharacterized protein. (725 aa)
SLC2A1MFS domain-containing protein; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (491 aa)
CDKN1AUncharacterized protein. (164 aa)
ENSVURP00010024966Tubulin-specific chaperone A; Belongs to the TBCA family. (77 aa)
ENSVURP00010024791Uncharacterized protein. (93 aa)
LTBRUncharacterized protein. (413 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (814 aa)
ENSVURP00010023428Uncharacterized protein. (125 aa)
ENSVURP00010022990Ldh_1_C domain-containing protein. (103 aa)
CREBBPUncharacterized protein. (2453 aa)
MKNK1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (431 aa)
MAP2K1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (393 aa)
LOC114024909Uncharacterized protein. (464 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (613 aa)
ENSVURP00010022394Uncharacterized protein. (72 aa)
PFKLUncharacterized protein. (726 aa)
ENSVURP00010022176L-lactate dehydrogenase. (218 aa)
LOC114053911Skp1_POZ domain-containing protein; Belongs to the SKP1 family. (112 aa)
ENSVURP00010021924Ldh_1_N domain-containing protein. (161 aa)
LDHBL-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (334 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1264 aa)
LOC114049654Uncharacterized protein. (466 aa)
LOC114049642-2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
MKNK2Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (470 aa)
LOC114047389-2TIR domain-containing protein; Belongs to the Toll-like receptor family. (881 aa)
ENSVURP00010020165Uncharacterized protein. (146 aa)
ENSVURP00010019785Gp_dh_C domain-containing protein. (162 aa)
PIK3R2Uncharacterized protein. (738 aa)
ENSVURP00010019471annotation not available (789 aa)
ENSVURP0001001944140S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family. (249 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (614 aa)
ENSVURP00010019093annotation not available (498 aa)
HKDC1Uncharacterized protein. (917 aa)
HK1Uncharacterized protein. (919 aa)
ENSVURP00010018718annotation not available (400 aa)
ENSVURP00010018604Ubiquitin-like domain-containing protein. (89 aa)
GAPDHGlyceraldehyde-3-phosphate dehydrogenase. (333 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1279 aa)
EGFRReceptor protein-tyrosine kinase. (1214 aa)
ENSVURP00010017868Ldh_1_N domain-containing protein. (89 aa)
CAMK2GProtein kinase domain-containing protein. (603 aa)
ENSVURP00010017456Uncharacterized protein. (400 aa)
TIMP1NTR domain-containing protein. (212 aa)
BCL2BCL2 apoptosis regulator. (256 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
RPS6KB1Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (539 aa)
PDHA1Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (395 aa)
INSInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (102 aa)
HK2Uncharacterized protein. (917 aa)
ENSVURP00010015255Glyceraldehyde-3-phosphate dehydrogenase. (333 aa)
ENSVURP00010015203Enolase_N domain-containing protein. (154 aa)
VHLUncharacterized protein. (158 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (703 aa)
LOC114045424Uncharacterized protein; Belongs to the LDH/MDH superfamily. (319 aa)
ENSVURP00010014402annotation not available (113 aa)
ENSVURP00010014299Ldh_1_N domain-containing protein. (113 aa)
ENSVURP00010014291annotation not available (318 aa)
ENSVURP00010014276Uncharacterized protein. (318 aa)
NOS2Nitric oxide synthase; Produces nitric oxide (NO). (1153 aa)
ENSVURP00010013807Ubiquitin-like domain-containing protein. (82 aa)
ALDOCFructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (364 aa)
EIF4EBP1Eukaryotic translation initiation factor 4E binding protein 1. (110 aa)
ENSVURP00010013035Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (387 aa)
LOC114052108Uncharacterized protein. (382 aa)
ENSVURP00010011447Ldh_1_N domain-containing protein. (108 aa)
RPS6KB2Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (474 aa)
MAP2K2Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (400 aa)
ENSVURP00010031637Uncharacterized protein. (512 aa)
LOC114029412Uncharacterized protein. (457 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (164 aa)
PIK3CDUncharacterized protein; Belongs to the PI3/PI4-kinase family. (1075 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2521 aa)
NPPAUncharacterized protein. (144 aa)
IGF1Insulin like growth factor 1. (229 aa)
CUL2CULLIN_2 domain-containing protein; Belongs to the cullin family. (745 aa)
EGLN2Fe2OG dioxygenase domain-containing protein. (388 aa)
ENSVURP00010031228Ldh_1_C domain-containing protein. (93 aa)
PFKPATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (811 aa)
ENSVURP00010030726Gp_dh_N domain-containing protein; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (266 aa)
ENSVURP00010030613VWFD domain-containing protein. (168 aa)
ENSVURP00010030608VWFD domain-containing protein. (158 aa)
ENSVURP00010030582Uncharacterized protein. (1696 aa)
ENSVURP00010030513Uncharacterized protein. (175 aa)
ENSVURP00010030368L-lactate dehydrogenase. (207 aa)
ENSVURP00010029927Uncharacterized protein. (64 aa)
EIF4E2Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family. (245 aa)
ENSVURP00010029282Uncharacterized protein. (409 aa)
ENSVURP00010029067annotation not available (466 aa)
ENSVURP00010028940Protein kinase domain-containing protein. (69 aa)
ENSVURP00010028836Gp_dh_N domain-containing protein. (281 aa)
STAT3Signal transducer and activator of transcription. (771 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (349 aa)
ENSVURP00010028054Uncharacterized protein. (54 aa)
ENSVURP00010028008Uncharacterized protein. (181 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1052 aa)
ENSVURP00010011398Uncharacterized protein. (135 aa)
ALDOAFructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (424 aa)
IGF1RTyrosine-protein kinase receptor. (1362 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
ANGPT2Fibrinogen C-terminal domain-containing protein. (495 aa)
ANGPT1Fibrinogen C-terminal domain-containing protein. (498 aa)
CAMK2ACalcium/calmodulin dependent protein kinase II alpha; Belongs to the protein kinase superfamily. (489 aa)
LOC114037540Tubulin-specific chaperone A; Belongs to the TBCA family. (76 aa)
ENSVURP00010010434Sulfatase domain-containing protein. (430 aa)
ENSVURP00010010429Sulfatase domain-containing protein. (132 aa)
ENSVURP00010010317Gp_dh_N domain-containing protein. (247 aa)
ENSVURP00010010314Uncharacterized protein; Belongs to the transferrin family. (712 aa)
TFRCUncharacterized protein. (770 aa)
LOC114049642Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
NOS3Nitric oxide synthase; Produces nitric oxide (NO). (1193 aa)
ENSVURP00010009820Uncharacterized protein. (73 aa)
CDKN1BUncharacterized protein. (199 aa)
LOC114037604Phosphoglycerate kinase. (417 aa)
ELOCElongin C. (112 aa)
ENSVURP00010008839Protein-serine/threonine kinase. (77 aa)
TEKUncharacterized protein. (1124 aa)
PFKMATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (782 aa)
CAMK2DProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (493 aa)
ERBB2Receptor protein-tyrosine kinase. (1255 aa)
PGK1Phosphoglycerate kinase. (417 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
EGFUncharacterized protein. (1191 aa)
VEGFAVascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (400 aa)
HMOX1Uncharacterized protein. (290 aa)
LOC114047389TIR domain-containing protein; Belongs to the Toll-like receptor family. (832 aa)
PDHBPyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (361 aa)
IFNGR2Fibronectin type-III domain-containing protein. (357 aa)
IFNGR1Uncharacterized protein. (492 aa)
EDN1Uncharacterized protein. (214 aa)
ENSVURP00010003961Uncharacterized protein. (109 aa)
ALDOBFructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (364 aa)
ENSVURP00010003469Fibrinogen C-terminal domain-containing protein. (498 aa)
ENSVURP00010003442Uncharacterized protein; Belongs to the LDH/MDH superfamily. (343 aa)
EGLN3Fe2OG dioxygenase domain-containing protein. (270 aa)
CAMK2BProtein kinase domain-containing protein. (546 aa)
LOC114050566Uncharacterized protein. (215 aa)
RBX1RING-type domain-containing protein. (108 aa)
ENSVURP00010002486Uncharacterized protein. (202 aa)
EP300Uncharacterized protein. (2440 aa)
ENO2Uncharacterized protein. (434 aa)
EIF4E1BEukaryotic translation initiation factor 4E family member 1B; Belongs to the eukaryotic initiation factor 4E family. (272 aa)
EIF4EUncharacterized protein; Belongs to the eukaryotic initiation factor 4E family. (217 aa)
RELARHD domain-containing protein. (538 aa)
HK3Uncharacterized protein. (913 aa)
ENO3Uncharacterized protein. (434 aa)
CYBBCytochrome b-245 beta chain. (572 aa)
ENSVURP00010001588annotation not available (128 aa)
ENSVURP00010001366Fe2OG dioxygenase domain-containing protein. (128 aa)
LOC114031174SERPIN domain-containing protein; Belongs to the serpin family. (400 aa)
INSRTyrosine-protein kinase receptor. (1374 aa)
ENSVURP00010001019annotation not available (409 aa)
EPOErythropoietin. (192 aa)
ELOBUbiquitin-like domain-containing protein. (118 aa)
ENSVURP000100004856PF2K domain-containing protein. (409 aa)
LDHAL-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (333 aa)
ENSVURP00010000389Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1256 aa)
LOC114042902Uncharacterized protein. (789 aa)
LDHCL-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (300 aa)
ENSVURP00010000232Uncharacterized protein. (48 aa)
ENSVURP00010000175annotation not available (595 aa)
LOC114034122Uncharacterized protein; Belongs to the transferrin family. (595 aa)
NFKB1Uncharacterized protein. (1007 aa)
FLT1Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1341 aa)
ENSVURP00010026384annotation not available (215 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
Your Current Organism:
Vombatus ursinus
NCBI taxonomy Id: 29139
Other names: V. ursinus, coarse-haired wombat, common wombat
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