STRINGSTRING
PIK3R2 PIK3R2 CDKN2D CDKN2D TSSK6 TSSK6 ENSVURP00010032508 ENSVURP00010032508 MAP2K2 MAP2K2 CCND1 CCND1 SETD7 SETD7 PIK3CD PIK3CD SLC35E3 SLC35E3 MDM2 MDM2 IGF1 IGF1 CDK2 CDK2 BCL6 BCL6 GABARAPL2 GABARAPL2 AGAP2 AGAP2 TSSK4 TSSK4 ENSVURP00010029762 ENSVURP00010029762 ENSVURP00010029726 ENSVURP00010029726 ENSVURP00010029723 ENSVURP00010029723 PCK2 PCK2 ENSVURP00010029636 ENSVURP00010029636 LOC114040462 LOC114040462 ENSVURP00010029571 ENSVURP00010029571 PRKAG1-2 PRKAG1-2 TGFBR2 TGFBR2 ENSVURP00010029463 ENSVURP00010029463 ENSVURP00010029406 ENSVURP00010029406 MAPK10 MAPK10 ENSVURP00010029153 ENSVURP00010029153 STAT3 STAT3 MAPK1 MAPK1 G6PC G6PC PLK2 PLK2 ENSVURP00010027140 ENSVURP00010027140 RNF6 RNF6 REM2 REM2 G6PC2 G6PC2 ENSVURP00010026388 ENSVURP00010026388 ENSVURP00010026384 ENSVURP00010026384 AKT2 AKT2 RBL2 RBL2 TSSK3 TSSK3 MAPK9 MAPK9 FOXO6 FOXO6 ENSVURP00010025661 ENSVURP00010025661 FOXJ3 FOXJ3 PIK3R1 PIK3R1 LDLRAD4 LDLRAD4 CCNB1 CCNB1 CDKN1A CDKN1A MAPK13 MAPK13 HOMER1 HOMER1 MAPK14 MAPK14 ENSVURP00010024795 ENSVURP00010024795 PLK3 PLK3 RNF111 RNF111 CCNB2 CCNB2 SGK2 SGK2 PCK1 PCK1 PMEPA1 PMEPA1 LOC114031532 LOC114031532 CREBBP CREBBP FOXJ2 FOXJ2 SMAD3 SMAD3 FOXO1 FOXO1 MAP2K1 MAP2K1 LOC114024909 LOC114024909 ENSVURP00010022363 ENSVURP00010022363 LOC114049914 LOC114049914 STK11 STK11 ENSVURP00010021762 ENSVURP00010021762 FBXO32 FBXO32 ENSVURP00010021499 ENSVURP00010021499 GADD45B GADD45B ENSVURP00010021329 ENSVURP00010021329 ENSVURP00010021023 ENSVURP00010021023 MAPK8 MAPK8 BCL2L11 BCL2L11 LOC114049642-2 LOC114049642-2 MYO9A MYO9A SIRT1 SIRT1 TSSK1B TSSK1B TSSK2 TSSK2 CHUK CHUK KRAS KRAS HOMER3 HOMER3 ENSVURP00010019784 ENSVURP00010019784 ENSVURP00010019760 ENSVURP00010019760 IL7R IL7R ENSVURP00010019444 ENSVURP00010019444 ENSVURP00010019409 ENSVURP00010019409 RASGEF1A RASGEF1A BRAF BRAF S1PR4 S1PR4 ATM ATM ENSVURP00010018459 ENSVURP00010018459 PLK1 PLK1 PRMT1 PRMT1 EGFR EGFR ENSVURP00010017722 ENSVURP00010017722 GADD45A GADD45A RAF1 RAF1 LOC114023950 LOC114023950 TNFSF10 TNFSF10 ENSVURP00010016554 ENSVURP00010016554 PIK3CA PIK3CA IL10 IL10 CAT CAT INS INS GRB2 GRB2 RAG1 RAG1 RAG2 RAG2 CDK3 CDK3 NLK NLK KLF2 KLF2 CCNG2 CCNG2 BNIP3 BNIP3 RASGEF1B RASGEF1B ENSVURP00010013724 ENSVURP00010013724 ENSVURP00010013568 ENSVURP00010013568 ATG12 ATG12 TGFB2 TGFB2 RASL11B RASL11B MYO9B MYO9B USP7 USP7 LOC114027938 LOC114027938 NRAS NRAS CSDE1 CSDE1 FBXO25 FBXO25 SOS2 SOS2 IKBKB IKBKB PIK3CB PIK3CB IGF1R IGF1R MAPK3 MAPK3 PLK4 PLK4 PRMT8 PRMT8 G6PC3 G6PC3 PRKAG2 PRKAG2 PRKAB2 PRKAB2 LOC114049642 LOC114049642 PRKAA2 PRKAA2 CCND2 CCND2 GABARAPL1 GABARAPL1 CDKN1B CDKN1B IRS1 IRS1 PRKAG1 PRKAG1 PRKAB1 PRKAB1 GADD45G GADD45G GRAP GRAP FASLG FASLG SUCO SUCO AKT1 AKT1 EGF EGF ENSVURP00010006608 ENSVURP00010006608 ENSVURP00010006464 ENSVURP00010006464 HRAS HRAS SGK1 SGK1 HOMER2 HOMER2 ENSVURP00010005096 ENSVURP00010005096 PRMT3 PRMT3 TGFB1 TGFB1 CSNK1E CSNK1E ENSVURP00010003699 ENSVURP00010003699 SLC2A4 SLC2A4 GABARAP GABARAP BCL6B BCL6B LOC114043698 LOC114043698 LOC114046825 LOC114046825 LOC114050566 LOC114050566 EP300 EP300 PRKAG3 PRKAG3 STK4 STK4 MAPK11 MAPK11 MAPK12 MAPK12 SOS1 SOS1 ENSVURP00010002081 ENSVURP00010002081 S1PR1 S1PR1 PRKAA1 PRKAA1 SMAD4 SMAD4 INSR INSR GEM GEM LOC114033910 LOC114033910 ENSVURP00010000036 ENSVURP00010000036 ENSVURP00010000035 ENSVURP00010000035
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PIK3R2Uncharacterized protein. (738 aa)
CDKN2DANK_REP_REGION domain-containing protein. (167 aa)
TSSK6Testis specific serine kinase 6; Belongs to the protein kinase superfamily. (270 aa)
ENSVURP00010032508Protein kinase domain-containing protein. (339 aa)
MAP2K2Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (400 aa)
CCND1Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (292 aa)
SETD7SET domain containing 7, histone lysine methyltransferase. (362 aa)
PIK3CDUncharacterized protein; Belongs to the PI3/PI4-kinase family. (1075 aa)
SLC35E3TPT domain-containing protein. (313 aa)
MDM2Uncharacterized protein. (534 aa)
IGF1Insulin like growth factor 1. (229 aa)
CDK2Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (346 aa)
BCL6Uncharacterized protein. (737 aa)
GABARAPL2Uncharacterized protein. (117 aa)
AGAP2Uncharacterized protein. (823 aa)
TSSK4Protein kinase domain-containing protein. (247 aa)
ENSVURP00010029762Uncharacterized protein. (112 aa)
ENSVURP00010029726annotation not available (264 aa)
ENSVURP00010029723TGF_BETA_2 domain-containing protein. (264 aa)
PCK2Uncharacterized protein. (640 aa)
ENSVURP00010029636annotation not available (151 aa)
LOC114040462Fork-head domain-containing protein. (500 aa)
ENSVURP00010029571annotation not available (136 aa)
PRKAG1-2Uncharacterized protein. (354 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (565 aa)
ENSVURP00010029463Uncharacterized protein. (330 aa)
ENSVURP00010029406IRS-type PTB domain-containing protein. (1133 aa)
MAPK10Mitogen-activated protein kinase. (449 aa)
ENSVURP00010029153Protein kinase domain-containing protein. (542 aa)
STAT3Signal transducer and activator of transcription. (771 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (349 aa)
G6PCGlucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (357 aa)
PLK2Serine/threonine-protein kinase PLK. (696 aa)
ENSVURP00010027140Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (467 aa)
RNF6RING-type domain-containing protein. (688 aa)
REM2GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (324 aa)
G6PC2Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (355 aa)
ENSVURP00010026388CYCLIN domain-containing protein; Belongs to the cyclin family. (229 aa)
ENSVURP00010026384annotation not available (215 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
RBL2RB transcriptional corepressor like 2. (1131 aa)
TSSK3Protein kinase domain-containing protein. (268 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
FOXO6Forkhead box O6. (509 aa)
ENSVURP00010025661Uncharacterized protein. (117 aa)
FOXJ3Fork-head domain-containing protein. (622 aa)
PIK3R1Uncharacterized protein. (725 aa)
LDLRAD4Uncharacterized protein. (292 aa)
CCNB1Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (416 aa)
CDKN1AUncharacterized protein. (164 aa)
MAPK13Mitogen-activated protein kinase. (356 aa)
HOMER1WH1 domain-containing protein. (354 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
ENSVURP00010024795annotation not available (225 aa)
PLK3Serine/threonine-protein kinase PLK. (649 aa)
RNF111RING-type domain-containing protein. (997 aa)
CCNB2Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (398 aa)
SGK2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (362 aa)
PCK1Uncharacterized protein. (622 aa)
PMEPA1Uncharacterized protein. (286 aa)
LOC114031532Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (225 aa)
CREBBPUncharacterized protein. (2453 aa)
FOXJ2Fork-head domain-containing protein. (566 aa)
SMAD3Mothers against decapentaplegic homolog. (426 aa)
FOXO1Forkhead box O1. (655 aa)
MAP2K1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (393 aa)
LOC114024909Uncharacterized protein. (464 aa)
ENSVURP00010022363annotation not available (408 aa)
LOC114049914SNARE-associated protein Snapin; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking and synaptic vesicle recycling; Belongs to t [...] (136 aa)
STK11Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (441 aa)
ENSVURP00010021762annotation not available (509 aa)
FBXO32Uncharacterized protein. (355 aa)
ENSVURP00010021499Uncharacterized protein. (546 aa)
GADD45BRibosomal_L7Ae domain-containing protein. (160 aa)
ENSVURP00010021329TGFb_propeptide domain-containing protein. (131 aa)
ENSVURP00010021023annotation not available (683 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
BCL2L11BCL2 like 11. (141 aa)
LOC114049642-2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
MYO9AUncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2597 aa)
SIRT1Sirtuin 1. (550 aa)
TSSK1BProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (366 aa)
TSSK2Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (356 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (730 aa)
KRASUncharacterized protein. (189 aa)
HOMER3WH1 domain-containing protein. (358 aa)
ENSVURP00010019784Uncharacterized protein. (218 aa)
ENSVURP00010019760Uncharacterized protein. (152 aa)
IL7RFibronectin type-III domain-containing protein. (455 aa)
ENSVURP00010019444F-box domain-containing protein. (361 aa)
ENSVURP00010019409Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (492 aa)
RASGEF1AUncharacterized protein. (485 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (741 aa)
S1PR4Sphingosine-1-phosphate receptor 4; Belongs to the G-protein coupled receptor 1 family. (338 aa)
ATMSerine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3064 aa)
ENSVURP00010018459GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (322 aa)
PLK1Serine/threonine-protein kinase PLK. (615 aa)
PRMT1Methyltransf_25 domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (372 aa)
EGFRReceptor protein-tyrosine kinase. (1214 aa)
ENSVURP00010017722SWIB domain-containing protein. (173 aa)
GADD45ARibosomal_L7Ae domain-containing protein. (166 aa)
RAF1Uncharacterized protein. (667 aa)
LOC114023950Uncharacterized protein. (203 aa)
TNFSF10Tumor necrosis factor ligand superfamily member. (299 aa)
ENSVURP00010016554Fork-head domain-containing protein. (487 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
IL10Uncharacterized protein. (206 aa)
CATCatalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (527 aa)
INSInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (102 aa)
GRB2Uncharacterized protein. (217 aa)
RAG1V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...] (1047 aa)
RAG2RAG2_PHD domain-containing protein. (528 aa)
CDK3Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (319 aa)
NLKMitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (528 aa)
KLF2Uncharacterized protein. (392 aa)
CCNG2CYCLIN domain-containing protein; Belongs to the cyclin family. (344 aa)
BNIP3Uncharacterized protein. (200 aa)
RASGEF1BUncharacterized protein. (496 aa)
ENSVURP00010013724annotation not available (305 aa)
ENSVURP00010013568FOXO-TAD domain-containing protein. (453 aa)
ATG12Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. (139 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (408 aa)
RASL11BUncharacterized protein. (254 aa)
MYO9BUncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2176 aa)
USP7Uncharacterized protein; Belongs to the peptidase C19 family. (1100 aa)
LOC114027938GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (305 aa)
NRASUncharacterized protein. (189 aa)
CSDE1Uncharacterized protein. (847 aa)
FBXO25Uncharacterized protein. (358 aa)
SOS2Uncharacterized protein. (1329 aa)
IKBKBProtein kinase domain-containing protein. (757 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1052 aa)
IGF1RTyrosine-protein kinase receptor. (1362 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
PLK4Uncharacterized protein. (964 aa)
PRMT8Uncharacterized protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (394 aa)
G6PC3acidPPc domain-containing protein. (378 aa)
PRKAG2Uncharacterized protein. (580 aa)
PRKAB2AMPKBI domain-containing protein. (274 aa)
LOC114049642Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
PRKAA2Non-specific serine/threonine protein kinase. (551 aa)
CCND2Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (290 aa)
GABARAPL1Uncharacterized protein. (140 aa)
CDKN1BUncharacterized protein. (199 aa)
IRS1Uncharacterized protein. (1242 aa)
PRKAG1Uncharacterized protein. (330 aa)
PRKAB1AMPKBI domain-containing protein. (274 aa)
GADD45GRibosomal_L7Ae domain-containing protein. (159 aa)
GRAPUncharacterized protein. (217 aa)
FASLGTNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (280 aa)
SUCOSUN domain-containing protein. (1267 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
EGFUncharacterized protein. (1191 aa)
ENSVURP00010006608Uncharacterized protein. (799 aa)
ENSVURP00010006464Uncharacterized protein. (1377 aa)
HRASUncharacterized protein. (189 aa)
SGK1Non-specific serine/threonine protein kinase. (525 aa)
HOMER2WH1 domain-containing protein. (342 aa)
ENSVURP00010005096Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (387 aa)
PRMT3C2H2-type domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (541 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (382 aa)
CSNK1EProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (431 aa)
ENSVURP00010003699Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (356 aa)
SLC2A4MFS domain-containing protein; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (509 aa)
GABARAPUncharacterized protein. (117 aa)
BCL6BUncharacterized protein. (502 aa)
LOC114043698Protein kinase domain-containing protein. (683 aa)
LOC114046825GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (303 aa)
LOC114050566Uncharacterized protein. (215 aa)
EP300Uncharacterized protein. (2440 aa)
PRKAG3Protein kinase AMP-activated non-catalytic subunit gamma 3. (358 aa)
STK4Uncharacterized protein. (487 aa)
MAPK11Mitogen-activated protein kinase. (362 aa)
MAPK12Mitogen-activated protein kinase. (365 aa)
SOS1Uncharacterized protein. (1332 aa)
ENSVURP00010002081Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
S1PR1G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (380 aa)
PRKAA1Non-specific serine/threonine protein kinase. (559 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
INSRTyrosine-protein kinase receptor. (1374 aa)
GEMGTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (296 aa)
LOC114033910Fibronectin type-III domain-containing protein. (455 aa)
ENSVURP00010000036Uncharacterized protein. (96 aa)
ENSVURP00010000035Uncharacterized protein. (210 aa)
Your Current Organism:
Vombatus ursinus
NCBI taxonomy Id: 29139
Other names: V. ursinus, coarse-haired wombat, common wombat
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