STRINGSTRING
LOC114031332 LOC114031332 PPP2R3A PPP2R3A PPP2R2B PPP2R2B ABCC1 ABCC1 MAPK3 MAPK3 TMIGD3 TMIGD3 PIK3CB PIK3CB PPP2R1A PPP2R1A LOC114049866 LOC114049866 ADAMTS17 ADAMTS17 CERS3 CERS3 CSDE1 CSDE1 NRAS NRAS ACER2 ACER2 ENSVURP00010013359 ENSVURP00010013359 PPP2R2D PPP2R2D SMPD2 SMPD2 SPHK1 SPHK1 SPHK2 SPHK2 PRKCG PRKCG ENSVURP00010014988 ENSVURP00010014988 PPP2R5A PPP2R5A LOC114053094 LOC114053094 S1PR3 S1PR3 LOC114040350 LOC114040350 ENSVURP00010015394 ENSVURP00010015394 ENSVURP00010015397 ENSVURP00010015397 CTSD CTSD PPP2CB PPP2CB SGPL1 SGPL1 ROCK2 ROCK2 PIK3CA PIK3CA GNA13 GNA13 PLD1 PLD1 GNAI1 GNAI1 BCL2 BCL2 BAX BAX RAF1 RAF1 ADORA1 ADORA1 MS4A2 MS4A2 S1PR4 S1PR4 GNAI3 GNAI3 PRKCA PRKCA ENSVURP00010019348 ENSVURP00010019348 ENSVURP00010019376 ENSVURP00010019376 SRMS SRMS PTK6 PTK6 PIK3R2 PIK3R2 ENSVURP00010019760 ENSVURP00010019760 ENSVURP00010019784 ENSVURP00010019784 SPTLC2 SPTLC2 ENSVURP00010019915 ENSVURP00010019915 KRAS KRAS LOC114049642-2 LOC114049642-2 PPP2R3B PPP2R3B SGPP2 SGPP2 MAPK8 MAPK8 PRKCE PRKCE ENSVURP00010021023 ENSVURP00010021023 ENSVURP00010021078 ENSVURP00010021078 ENSVURP00010021576 ENSVURP00010021576 GAB2 GAB2 PRKCB PRKCB LOC114024909 LOC114024909 MAP2K1 MAP2K1 ENSVURP00010022760 ENSVURP00010022760 AADAC AADAC KNG1 KNG1 RAC1 RAC1 GNAI2 GNAI2 RHOA RHOA PPP2R5E PPP2R5E SGPP1 SGPP1 TNFRSF1A TNFRSF1A OPRD1 OPRD1 GNA12 GNA12 MAPK14 MAPK14 MAPK13 MAPK13 PIK3R1 PIK3R1 PPP2R1B PPP2R1B MAPK9 MAPK9 ENSVURP00010025906 ENSVURP00010025906 AKT2 AKT2 PPP2R3C PPP2R3C ENSVURP00010026768 ENSVURP00010026768 CERS6 CERS6 NFKB1 NFKB1 TRADD TRADD MAPK1 MAPK1 PPP2R2C PPP2R2C MAPK10 MAPK10 TRAF2 TRAF2 FYN FYN LOC114031801 LOC114031801 PRKCZ PRKCZ BID BID PIK3CD PIK3CD ACER1 ACER1 ENSVURP00010032211 ENSVURP00010032211 MAP2K2 MAP2K2 ENSVURP00010032360 ENSVURP00010032360 DEGS2 DEGS2 LOC114029565 LOC114029565 LOC114029572 LOC114029572 LOC114029611 LOC114029611 ENSVURP00010032385 ENSVURP00010032385 LOC114029638 LOC114029638 S1PR2 S1PR2 ASAH1 ASAH1 PPP2R5B PPP2R5B FCER1A FCER1A LOC114043698 LOC114043698 BDKRB2 BDKRB2 TP53 TP53 MAP3K5 MAP3K5 SGMS2 SGMS2 ASAH2 ASAH2 SGMS1 SGMS1 ENSVURP00010005096 ENSVURP00010005096 RAC2 RAC2 PPP2R5C PPP2R5C PLCB3 PLCB3 SMPD1 SMPD1 HRAS HRAS AKT1 AKT1 TNF TNF LOC114042749 LOC114042749 RELA RELA PPP2R2A PPP2R2A S1PR1 S1PR1 PLD2 PLD2 MAPK12 MAPK12 MAPK11 MAPK11 PPP2R5D PPP2R5D LOC114054070 LOC114054070 ENSVURP00010008815 ENSVURP00010008815 CERS5 CERS5 SPTLC3 SPTLC3 PPP2CA PPP2CA PLCB4 PLCB4 NOS3 NOS3 PLCB1 PLCB1 LOC114049642 LOC114049642 PLCB2 PLCB2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC114031332Uncharacterized protein. (192 aa)
PPP2R3AEF-hand domain-containing protein. (1155 aa)
PPP2R2BSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (443 aa)
ABCC1Uncharacterized protein. (1585 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
TMIGD3G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (354 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1052 aa)
PPP2R1AUncharacterized protein. (589 aa)
LOC114049866Lipid_DES domain-containing protein. (323 aa)
ADAMTS17ADAM metallopeptidase with thrombospondin type 1 motif 17. (1120 aa)
CERS3Uncharacterized protein. (373 aa)
CSDE1Uncharacterized protein. (847 aa)
NRASUncharacterized protein. (189 aa)
ACER2Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (275 aa)
ENSVURP00010013359Uncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1296 aa)
PPP2R2DSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (443 aa)
SMPD2Sphingomyelin phosphodiesterase 2. (429 aa)
SPHK1DAGKc domain-containing protein. (394 aa)
SPHK2DAGKc domain-containing protein. (732 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (703 aa)
ENSVURP00010014988Abhydrolase_3 domain-containing protein. (201 aa)
PPP2R5ASerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (496 aa)
LOC114053094Uncharacterized protein. (403 aa)
S1PR3G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (377 aa)
LOC114040350G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (393 aa)
ENSVURP00010015394annotation not available (393 aa)
ENSVURP00010015397Uncharacterized protein. (123 aa)
CTSDPeptidase A1 domain-containing protein; Belongs to the peptidase A1 family. (411 aa)
PPP2CBSerine/threonine-protein phosphatase. (309 aa)
SGPL1Uncharacterized protein. (568 aa)
ROCK2Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1388 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
GNA13Uncharacterized protein. (377 aa)
PLD1Phospholipase. (1035 aa)
GNAI1Uncharacterized protein. (359 aa)
BCL2BCL2 apoptosis regulator. (256 aa)
BAXUncharacterized protein. (200 aa)
RAF1Uncharacterized protein. (667 aa)
ADORA1Adenosine receptor A1; Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (325 aa)
MS4A2Uncharacterized protein. (249 aa)
S1PR4Sphingosine-1-phosphate receptor 4; Belongs to the G-protein coupled receptor 1 family. (338 aa)
GNAI3Uncharacterized protein. (354 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (614 aa)
ENSVURP00010019348Uncharacterized protein. (196 aa)
ENSVURP00010019376annotation not available (380 aa)
SRMSTyrosine-protein kinase. (514 aa)
PTK6Tyrosine-protein kinase. (453 aa)
PIK3R2Uncharacterized protein. (738 aa)
ENSVURP00010019760Uncharacterized protein. (152 aa)
ENSVURP00010019784Uncharacterized protein. (218 aa)
SPTLC2Aminotran_1_2 domain-containing protein. (565 aa)
ENSVURP00010019915TLC domain-containing protein. (241 aa)
KRASUncharacterized protein. (189 aa)
LOC114049642-2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
PPP2R3BEF-hand domain-containing protein. (580 aa)
SGPP2Sphingosine-1-phosphate phosphatase 2. (353 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
PRKCEProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (658 aa)
ENSVURP00010021023annotation not available (683 aa)
ENSVURP00010021078annotation not available (192 aa)
ENSVURP00010021576annotation not available (323 aa)
GAB2PH domain-containing protein. (682 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (613 aa)
LOC114024909Uncharacterized protein. (464 aa)
MAP2K1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (393 aa)
ENSVURP00010022760Uncharacterized protein. (125 aa)
AADACUncharacterized protein. (393 aa)
KNG1Uncharacterized protein. (618 aa)
RAC1Uncharacterized protein. (211 aa)
GNAI2Uncharacterized protein. (355 aa)
RHOAUncharacterized protein. (193 aa)
PPP2R5ESerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (467 aa)
SGPP1Sphingosine-1-phosphate phosphatase 1. (422 aa)
TNFRSF1AUncharacterized protein. (459 aa)
OPRD1G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (369 aa)
GNA12Uncharacterized protein. (387 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
MAPK13Mitogen-activated protein kinase. (356 aa)
PIK3R1Uncharacterized protein. (725 aa)
PPP2R1BUncharacterized protein. (662 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
ENSVURP00010025906annotation not available (211 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
PPP2R3CEF-hand_13 domain-containing protein. (449 aa)
ENSVURP00010026768annotation not available (920 aa)
CERS6Uncharacterized protein. (393 aa)
NFKB1Uncharacterized protein. (1007 aa)
TRADDDeath domain-containing protein. (313 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (349 aa)
PPP2R2CSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (447 aa)
MAPK10Mitogen-activated protein kinase. (449 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (633 aa)
FYNTyrosine-protein kinase. (537 aa)
LOC114031801Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1355 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (592 aa)
BIDBH3-interacting domain death agonist; Counters the protective effect of Bcl-2. (191 aa)
PIK3CDUncharacterized protein; Belongs to the PI3/PI4-kinase family. (1075 aa)
ACER1Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (268 aa)
ENSVURP00010032211Serine/threonine-protein phosphatase. (309 aa)
MAP2K2Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (400 aa)
ENSVURP00010032360Uncharacterized protein. (395 aa)
DEGS2Lipid_DES domain-containing protein. (323 aa)
LOC114029565Uncharacterized protein. (385 aa)
LOC114029572Uncharacterized protein. (396 aa)
LOC114029611Uncharacterized protein. (364 aa)
ENSVURP00010032385Uncharacterized protein. (363 aa)
LOC114029638Uncharacterized protein. (397 aa)
S1PR2G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (350 aa)
ASAH1Uncharacterized protein; Belongs to the acid ceramidase family. (398 aa)
PPP2R5BSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (494 aa)
FCER1AIg-like domain-containing protein. (313 aa)
LOC114043698Protein kinase domain-containing protein. (683 aa)
BDKRB2Bradykinin receptor B2; Belongs to the G-protein coupled receptor 1 family. (372 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (370 aa)
MAP3K5Protein kinase domain-containing protein. (1387 aa)
SGMS2PAP2_C domain-containing protein. (365 aa)
ASAH2Neutral ceramidase. (784 aa)
SGMS1SAM domain-containing protein. (411 aa)
ENSVURP00010005096Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (387 aa)
RAC2Uncharacterized protein. (306 aa)
PPP2R5CSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (565 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1208 aa)
SMPD1Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. (617 aa)
HRASUncharacterized protein. (189 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
TNFTNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (232 aa)
LOC114042749Uncharacterized protein. (380 aa)
RELARHD domain-containing protein. (538 aa)
PPP2R2ASerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (446 aa)
S1PR1G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (380 aa)
PLD2Phospholipase. (934 aa)
MAPK12Mitogen-activated protein kinase. (365 aa)
MAPK11Mitogen-activated protein kinase. (362 aa)
PPP2R5DSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (602 aa)
LOC114054070Uncharacterized protein. (920 aa)
ENSVURP00010008815Aminotran_1_2 domain-containing protein. (520 aa)
CERS5Uncharacterized protein. (393 aa)
SPTLC3Aminotran_1_2 domain-containing protein. (552 aa)
PPP2CASerine/threonine-protein phosphatase. (309 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1206 aa)
NOS3Nitric oxide synthase; Produces nitric oxide (NO). (1193 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1117 aa)
LOC114049642Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1187 aa)
Your Current Organism:
Vombatus ursinus
NCBI taxonomy Id: 29139
Other names: V. ursinus, coarse-haired wombat, common wombat
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