STRINGSTRING
CDKN1A CDKN1A ENSVURP00010000035 ENSVURP00010000035 ENSVURP00010000036 ENSVURP00010000036 ENSVURP00010000102 ENSVURP00010000102 ENSVURP00010000112 ENSVURP00010000112 MCM7 MCM7 ENSVURP00010000135 ENSVURP00010000135 SMAD2 SMAD2 HDAC1 HDAC1 ENSVURP00010000461 ENSVURP00010000461 ENSVURP00010000594 ENSVURP00010000594 CDK1 CDK1 LOC114046348 LOC114046348 ENSVURP00010001148 ENSVURP00010001148 ZBTB17 ZBTB17 SMAD4 SMAD4 TMEM82 TMEM82 CDC7 CDC7 LOC114046231 LOC114046231 CDC14A CDC14A E2F3 E2F3 YWHAB YWHAB EP300 EP300 RBX1 RBX1 LOC114031927 LOC114031927 LOC114031680 LOC114031680 ENSVURP00010003699 ENSVURP00010003699 RAD21L1 RAD21L1 ENSVURP00010003848 ENSVURP00010003848 TGFB1 TGFB1 YWHAG YWHAG TP53 TP53 ENSVURP00010004866 ENSVURP00010004866 ENSVURP00010004877 ENSVURP00010004877 PTTG1 PTTG1 ANAPC5 ANAPC5 STAG2 STAG2 WEE1 WEE1 MCM5 MCM5 ANAPC4 ANAPC4 ANAPC7 ANAPC7 TTK TTK ENSVURP00010006218 ENSVURP00010006218 ENSVURP00010006488 ENSVURP00010006488 ORC4 ORC4 ENSVURP00010007025 ENSVURP00010007025 GADD45G GADD45G ENSVURP00010007983 ENSVURP00010007983 ORC3 ORC3 LOC114034259 LOC114034259 LOC114034259-2 LOC114034259-2 ENSVURP00010008321 ENSVURP00010008321 ANAPC2 ANAPC2 CDKN2B CDKN2B LOC114025930 LOC114025930 SFN SFN MCM6 MCM6 YWHAZ YWHAZ ENSVURP00010009165 ENSVURP00010009165 CDKN1B CDKN1B SKP1 SKP1 CCND2 CCND2 ZNF652 ZNF652 ANAPC13 ANAPC13 BUB1B BUB1B YWHAE YWHAE CCND3 CCND3 STAG1 STAG1 CDC14B CDC14B ANAPC11 ANAPC11 FAM126B FAM126B ORC2 ORC2 CDC23 CDC23 CDC25C CDC25C CDC27 CDC27 TFDP2 TFDP2 CHEK2 CHEK2 ATR ATR TGFB2 TGFB2 ANAPC10 ANAPC10 CDK20 CDK20 ORC5 ORC5 CDK3 CDK3 ESPL1 ESPL1 ENSVURP00010015181 ENSVURP00010015181 LOC114030664 LOC114030664 PCNA PCNA MAD2L1 MAD2L1 AP5S1 AP5S1 CDC25B CDC25B ENSVURP00010016188 ENSVURP00010016188 ENSVURP00010016197 ENSVURP00010016197 CCNE1 CCNE1 ENSVURP00010016370 ENSVURP00010016370 LOC114040384 LOC114040384 ENSVURP00010016528 ENSVURP00010016528 ORC6 ORC6 CDC25A CDC25A MCM3 MCM3 MYNN MYNN GADD45A GADD45A FBXW12 FBXW12 RBL1 RBL1 ENSVURP00010017722 ENSVURP00010017722 ENSVURP00010017759 ENSVURP00010017759 PLK1 PLK1 ZBTB46 ZBTB46 ATM ATM ENSVURP00010019291 ENSVURP00010019291 ENSVURP00010019444 ENSVURP00010019444 GSK3B GSK3B ENSVURP00010019921 ENSVURP00010019921 CDC45 CDC45 SMC1A SMC1A BUB1 BUB1 LOC114041161 LOC114041161 ANAPC1 ANAPC1 YWHAQ YWHAQ MCM2 MCM2 CDC26 CDC26 GADD45B GADD45B ENSVURP00010021423 ENSVURP00010021423 CUL1 CUL1 CCNA1 CCNA1 LOC114049914 LOC114049914 ENSVURP00010022363 ENSVURP00010022363 RAD21 RAD21 ENSVURP00010022536 ENSVURP00010022536 SMAD3 SMAD3 CREBBP CREBBP CCNH CCNH CCNE2 CCNE2 ENSVURP00010023486 ENSVURP00010023486 CDKN2C CDKN2C ORC1 ORC1 CCNB2 CCNB2 MAD1L1 MAD1L1 ENSVURP00010025164 ENSVURP00010025164 E2F1 E2F1 CDC20 CDC20 CDK7 CDK7 CCNB1 CCNB1 RBL2 RBL2 ENSVURP00010026388 ENSVURP00010026388 ENSVURP00010027337 ENSVURP00010027337 ENSVURP00010028164 ENSVURP00010028164 E2F4 E2F4 ENSVURP00010028318 ENSVURP00010028318 CHEK1 CHEK1 CDK6 CDK6 ENSVURP00010029571 ENSVURP00010029571 ENSVURP00010029723 ENSVURP00010029723 ENSVURP00010029726 ENSVURP00010029726 ENSVURP00010029926 ENSVURP00010029926 ENSVURP00010029929 ENSVURP00010029929 HDAC2 HDAC2 CDK4 CDK4 ENSVURP00010030012 ENSVURP00010030012 E2F2 E2F2 RB1 RB1 CDK2 CDK2 ENSVURP00010031277 ENSVURP00010031277 MAD2L2 MAD2L2 MDM2 MDM2 SMC1B SMC1B CCND1 CCND1 FZR1 FZR1 CDKN2D CDKN2D SMC3 SMC3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CDKN1AUncharacterized protein. (164 aa)
ENSVURP00010000035Uncharacterized protein. (210 aa)
ENSVURP00010000036Uncharacterized protein. (96 aa)
ENSVURP0001000010214_3_3 domain-containing protein; Belongs to the 14-3-3 family. (231 aa)
ENSVURP00010000112annotation not available (231 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (722 aa)
ENSVURP00010000135WD_REPEATS_REGION domain-containing protein. (486 aa)
SMAD2Mothers against decapentaplegic homolog. (467 aa)
HDAC1Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (482 aa)
ENSVURP00010000461WD_REPEATS_REGION domain-containing protein. (269 aa)
ENSVURP00010000594Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (492 aa)
CDK1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (297 aa)
LOC114046348Transcription factor. (411 aa)
ENSVURP00010001148Uncharacterized protein. (293 aa)
ZBTB17Zinc finger and BTB domain containing 17. (750 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
TMEM82Uncharacterized protein. (324 aa)
CDC7Protein kinase domain-containing protein. (565 aa)
LOC114046231TPR_REGION domain-containing protein. (545 aa)
CDC14AUncharacterized protein. (592 aa)
E2F3E2F_TDP domain-containing protein. (460 aa)
YWHAB14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (263 aa)
EP300Uncharacterized protein. (2440 aa)
RBX1RING-type domain-containing protein. (108 aa)
LOC114031927DNA helicase; Belongs to the MCM family. (864 aa)
LOC114031680Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (3993 aa)
ENSVURP00010003699Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (356 aa)
RAD21L1Uncharacterized protein. (563 aa)
ENSVURP00010003848Uncharacterized protein. (502 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (382 aa)
YWHAG14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (247 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (370 aa)
ENSVURP0001000486614_3_3 domain-containing protein; Belongs to the 14-3-3 family. (125 aa)
ENSVURP00010004877WD_REPEATS_REGION domain-containing protein. (489 aa)
PTTG1Uncharacterized protein. (200 aa)
ANAPC5Uncharacterized protein. (757 aa)
STAG2SCD domain-containing protein. (1262 aa)
WEE1Protein kinase domain-containing protein. (433 aa)
MCM5DNA helicase; Belongs to the MCM family. (734 aa)
ANAPC4Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. (768 aa)
ANAPC7TPR_REGION domain-containing protein. (565 aa)
TTKProtein kinase domain-containing protein. (906 aa)
ENSVURP00010006218annotation not available (3993 aa)
ENSVURP00010006488annotation not available (864 aa)
ORC4Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (436 aa)
ENSVURP00010007025Protein kinase domain-containing protein. (224 aa)
GADD45GRibosomal_L7Ae domain-containing protein. (159 aa)
ENSVURP00010007983annotation not available (411 aa)
ORC3ORC_WH_C domain-containing protein. (714 aa)
LOC114034259WD_REPEATS_REGION domain-containing protein. (324 aa)
LOC114034259-2WD_REPEATS_REGION domain-containing protein. (328 aa)
ENSVURP00010008321annotation not available (529 aa)
ANAPC2CULLIN_2 domain-containing protein; Belongs to the cullin family. (1295 aa)
CDKN2BANK_REP_REGION domain-containing protein. (139 aa)
LOC114025930Uncharacterized protein. (172 aa)
SFN14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (254 aa)
MCM6DNA helicase; Belongs to the MCM family. (821 aa)
YWHAZ14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (245 aa)
ENSVURP0001000916514_3_3 domain-containing protein; Belongs to the 14-3-3 family. (212 aa)
CDKN1BUncharacterized protein. (199 aa)
SKP1Uncharacterized protein; Belongs to the SKP1 family. (163 aa)
CCND2Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (290 aa)
ZNF652Uncharacterized protein. (604 aa)
ANAPC13Uncharacterized protein. (74 aa)
BUB1BBUB1 N-terminal domain-containing protein. (1044 aa)
YWHAE14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (255 aa)
CCND3Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (292 aa)
STAG1SCD domain-containing protein. (1258 aa)
CDC14BUncharacterized protein. (500 aa)
ANAPC11Uncharacterized protein. (122 aa)
FAM126BUncharacterized protein. (529 aa)
ORC2Uncharacterized protein. (614 aa)
CDC23TPR_REGION domain-containing protein. (595 aa)
CDC25CRhodanese domain-containing protein. (444 aa)
CDC27Uncharacterized protein. (833 aa)
TFDP2Transcription factor. (420 aa)
CHEK2Uncharacterized protein. (531 aa)
ATRUncharacterized protein; Belongs to the PI3/PI4-kinase family. (2656 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (408 aa)
ANAPC10DOC domain-containing protein. (203 aa)
CDK20Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (358 aa)
ORC5AAA_16 domain-containing protein. (435 aa)
CDK3Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (319 aa)
ESPL1Peptidase C50 domain-containing protein. (2124 aa)
ENSVURP00010015181Uncharacterized protein. (100 aa)
LOC114030664Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (448 aa)
PCNAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
MAD2L1HORMA domain-containing protein. (205 aa)
AP5S1Uncharacterized protein. (200 aa)
CDC25BRhodanese domain-containing protein. (581 aa)
ENSVURP00010016188Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (272 aa)
ENSVURP00010016197Cyclin_N2 domain-containing protein. (148 aa)
CCNE1Cyclin E1; Belongs to the cyclin family. (370 aa)
ENSVURP00010016370Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (539 aa)
LOC114040384Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (558 aa)
ENSVURP00010016528Uncharacterized protein. (129 aa)
ORC6Uncharacterized protein. (249 aa)
CDC25ARhodanese domain-containing protein. (514 aa)
MCM3DNA helicase; Belongs to the MCM family. (809 aa)
MYNNUncharacterized protein. (612 aa)
GADD45ARibosomal_L7Ae domain-containing protein. (166 aa)
FBXW12Uncharacterized protein. (468 aa)
RBL1Uncharacterized protein. (1065 aa)
ENSVURP00010017722SWIB domain-containing protein. (173 aa)
ENSVURP00010017759annotation not available (448 aa)
PLK1Serine/threonine-protein kinase PLK. (615 aa)
ZBTB46Uncharacterized protein. (666 aa)
ATMSerine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3064 aa)
ENSVURP00010019291annotation not available (502 aa)
ENSVURP00010019444F-box domain-containing protein. (361 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (389 aa)
ENSVURP0001001992114_3_3 domain-containing protein; Belongs to the 14-3-3 family. (96 aa)
CDC45Uncharacterized protein. (573 aa)
SMC1AStructural maintenance of chromosomes protein. (1196 aa)
BUB1Uncharacterized protein. (1119 aa)
LOC114041161SCD domain-containing protein. (1200 aa)
ANAPC1APC1_C domain-containing protein. (1971 aa)
YWHAQ14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (245 aa)
MCM2DNA helicase; Belongs to the MCM family. (908 aa)
CDC26Uncharacterized protein. (85 aa)
GADD45BRibosomal_L7Ae domain-containing protein. (160 aa)
ENSVURP00010021423Uncharacterized protein; Belongs to the cyclin family. (276 aa)
CUL1CULLIN_2 domain-containing protein; Belongs to the cullin family. (775 aa)
CCNA1Cyclin A1; Belongs to the cyclin family. (414 aa)
LOC114049914SNARE-associated protein Snapin; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking and synaptic vesicle recycling; Belongs to t [...] (136 aa)
ENSVURP00010022363annotation not available (408 aa)
RAD21Uncharacterized protein. (634 aa)
ENSVURP00010022536Uncharacterized protein. (882 aa)
SMAD3Mothers against decapentaplegic homolog. (426 aa)
CREBBPUncharacterized protein. (2453 aa)
CCNHCYCLIN domain-containing protein; Belongs to the cyclin family. (323 aa)
CCNE2Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (462 aa)
ENSVURP00010023486E2F_TDP domain-containing protein. (341 aa)
CDKN2CCyclin dependent kinase inhibitor 2C. (167 aa)
ORC1Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (857 aa)
CCNB2Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (398 aa)
MAD1L1FtsJ domain-containing protein. (841 aa)
ENSVURP00010025164WD_REPEATS_REGION domain-containing protein. (380 aa)
E2F1E2F transcription factor 1. (431 aa)
CDC20WD_REPEATS_REGION domain-containing protein. (538 aa)
CDK7Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (346 aa)
CCNB1Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (416 aa)
RBL2RB transcriptional corepressor like 2. (1131 aa)
ENSVURP00010026388CYCLIN domain-containing protein; Belongs to the cyclin family. (229 aa)
ENSVURP00010027337Skp1_POZ domain-containing protein. (59 aa)
ENSVURP00010028164Uncharacterized protein. (702 aa)
E2F4E2F_TDP domain-containing protein. (398 aa)
ENSVURP00010028318annotation not available (341 aa)
CHEK1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (485 aa)
CDK6Cyclin dependent kinase 6; Belongs to the protein kinase superfamily. (294 aa)
ENSVURP00010029571annotation not available (136 aa)
ENSVURP00010029723TGF_BETA_2 domain-containing protein. (264 aa)
ENSVURP00010029726annotation not available (264 aa)
ENSVURP00010029926DBF4-type domain-containing protein. (489 aa)
ENSVURP00010029929Uncharacterized protein. (153 aa)
HDAC2Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (488 aa)
CDK4Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (338 aa)
ENSVURP00010030012Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (379 aa)
E2F2E2F transcription factor 2. (431 aa)
RB1Uncharacterized protein. (927 aa)
CDK2Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (346 aa)
ENSVURP00010031277Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (262 aa)
MAD2L2HORMA domain-containing protein. (211 aa)
MDM2Uncharacterized protein. (534 aa)
SMC1BStructural maintenance of chromosomes protein. (1233 aa)
CCND1Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (292 aa)
FZR1WD_REPEATS_REGION domain-containing protein. (493 aa)
CDKN2DANK_REP_REGION domain-containing protein. (167 aa)
SMC3Structural maintenance of chromosomes protein. (1217 aa)
Your Current Organism:
Vombatus ursinus
NCBI taxonomy Id: 29139
Other names: V. ursinus, coarse-haired wombat, common wombat
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