STRINGSTRING
BMP6 BMP6 TGFB1 TGFB1 BMPR1B BMPR1B BMP8A BMP8A ID1 ID1 RBX1 RBX1 MATN4 MATN4 EP300 EP300 TNF TNF LTBP3 LTBP3 PITX3 PITX3 ENSVURP00010002081 ENSVURP00010002081 LOC114043187 LOC114043187 SMAD4 SMAD4 LOC114046348 LOC114046348 LOC114043227 LOC114043227 SMAD7 SMAD7 SMAD2 SMAD2 FSTL3 FSTL3 ID4 ID4 RPS6KB2 RPS6KB2 FBN3 FBN3 ENSVURP00010032211 ENSVURP00010032211 BAMBI BAMBI IFNG IFNG LTBP4 LTBP4 ENSVURP00010030642 ENSVURP00010030642 USF2 USF2 PKNOX1 PKNOX1 CHRD CHRD LOC114031801 LOC114031801 ID3 ID3 INHBC INHBC INHBE INHBE ENSVURP00010030097 ENSVURP00010030097 ENSVURP00010029726 ENSVURP00010029726 ENSVURP00010029723 ENSVURP00010029723 ENSVURP00010029571 ENSVURP00010029571 TGFBR2 TGFBR2 PKNOX2 PKNOX2 ENSVURP00010028940 ENSVURP00010028940 LOC114045863-2 LOC114045863-2 ENSVURP00010028522 ENSVURP00010028522 MAPK1 MAPK1 ENSVURP00010028318 ENSVURP00010028318 E2F4 E2F4 FST FST ENSVURP00010027337 ENSVURP00010027337 LOC114054202 LOC114054202 ENSVURP00010026500 ENSVURP00010026500 NEO1 NEO1 PPP2R1B PPP2R1B LOC114053902 LOC114053902 ENSVURP00010025222 ENSVURP00010025222 LTBP1 LTBP1 GDF5 GDF5 TGIF2 TGIF2 THSD4 THSD4 BMP7 BMP7 ZFYVE9 ZFYVE9 FAM151B FAM151B LTBP2 LTBP2 SMURF1 SMURF1 RHOA RHOA ENSVURP00010023486 ENSVURP00010023486 INTS8 INTS8 CREBBP CREBBP SMAD3 SMAD3 SMAD6 SMAD6 ENSVURP00010022363 ENSVURP00010022363 LOC114049914 LOC114049914 ENSVURP00010021762 ENSVURP00010021762 SMAD9 SMAD9 CUL1 CUL1 ENSVURP00010021329 ENSVURP00010021329 ENSVURP00010021189 ENSVURP00010021189 BMPR1A BMPR1A ENSVURP00010020877 ENSVURP00010020877 LOC114045863 LOC114045863 AMH AMH LOC114045927 LOC114045927 SMURF2 SMURF2 DCN DCN ENSVURP00010019930 ENSVURP00010019930 ENSVURP00010019792 ENSVURP00010019792 LOC114043227-2 LOC114043227-2 NODAL NODAL ENSVURP00010018398 ENSVURP00010018398 ANKFN1 ANKFN1 ACVR2B ACVR2B NOG NOG ENSVURP00010017759 ENSVURP00010017759 RBL1 RBL1 FMOD FMOD INHBA INHBA ENSVURP00010017255 ENSVURP00010017255 RPS6KB1 RPS6KB1 PPP2CB PPP2CB LOC114030664 LOC114030664 INHBB INHBB LOC114031682 LOC114031682 SP1 SP1 AMHR2 AMHR2 BMP5 BMP5 SMAD1 SMAD1 ID2 ID2 ENSVURP00010013359 ENSVURP00010013359 TGFB2 TGFB2 LOC114049601 LOC114049601 GREM1 GREM1 PPP2R1A PPP2R1A MAPK3 MAPK3 THBS1 THBS1 RGMA RGMA SMAD5 SMAD5 ACVR1B ACVR1B PITX1 PITX1 BMP4 BMP4 PPP2CA PPP2CA SKP1 SKP1 LOC114049823 LOC114049823 MATN2 MATN2 ENSVURP00010008132 ENSVURP00010008132 ENSVURP00010007983 ENSVURP00010007983 LOC114034230 LOC114034230 BMPR2 BMPR2 FBN1 FBN1 ACVR2A ACVR2A PITX2 PITX2 ENSVURP00010005678 ENSVURP00010005678
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BMP6TGF_BETA_2 domain-containing protein. (536 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (382 aa)
BMPR1BReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (534 aa)
BMP8ATGF_BETA_2 domain-containing protein. (436 aa)
ID1BHLH domain-containing protein. (151 aa)
RBX1RING-type domain-containing protein. (108 aa)
MATN4Uncharacterized protein. (596 aa)
EP300Uncharacterized protein. (2440 aa)
TNFTNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (232 aa)
LTBP3Uncharacterized protein. (1287 aa)
PITX3Homeobox protein. (305 aa)
ENSVURP00010002081Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
LOC114043187Uncharacterized protein. (425 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
LOC114046348Transcription factor. (411 aa)
LOC114043227PLAC domain-containing protein. (1112 aa)
SMAD7Mothers against decapentaplegic homolog. (434 aa)
SMAD2Mothers against decapentaplegic homolog. (467 aa)
FSTL3Uncharacterized protein. (249 aa)
ID4BHLH domain-containing protein. (163 aa)
RPS6KB2Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (474 aa)
FBN3Uncharacterized protein. (2784 aa)
ENSVURP00010032211Serine/threonine-protein phosphatase. (309 aa)
BAMBIBMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. (260 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (164 aa)
LTBP4Uncharacterized protein. (1585 aa)
ENSVURP00010030642Uncharacterized protein. (80 aa)
USF2Upstream transcription factor 2, c-fos interacting. (322 aa)
PKNOX1Homeobox domain-containing protein. (436 aa)
CHRDUncharacterized protein. (1044 aa)
LOC114031801Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1355 aa)
ID3BHLH domain-containing protein. (118 aa)
INHBCTGF_BETA_2 domain-containing protein. (360 aa)
INHBETGF_BETA_2 domain-containing protein. (348 aa)
ENSVURP00010030097annotation not available (247 aa)
ENSVURP00010029726annotation not available (264 aa)
ENSVURP00010029723TGF_BETA_2 domain-containing protein. (264 aa)
ENSVURP00010029571annotation not available (136 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (565 aa)
PKNOX2Homeobox domain-containing protein. (474 aa)
ENSVURP00010028940Protein kinase domain-containing protein. (69 aa)
LOC114045863-2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (493 aa)
ENSVURP00010028522annotation not available (511 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (349 aa)
ENSVURP00010028318annotation not available (341 aa)
E2F4E2F_TDP domain-containing protein. (398 aa)
FSTUncharacterized protein. (343 aa)
ENSVURP00010027337Skp1_POZ domain-containing protein. (59 aa)
LOC114054202Uncharacterized protein. (327 aa)
ENSVURP00010026500annotation not available (439 aa)
NEO1Neogenin 1. (1408 aa)
PPP2R1BUncharacterized protein. (662 aa)
LOC114053902Uncharacterized protein. (327 aa)
ENSVURP00010025222TGF_BETA_2 domain-containing protein. (439 aa)
LTBP1Uncharacterized protein. (1705 aa)
GDF5TGF_BETA_2 domain-containing protein. (495 aa)
TGIF2Homeobox domain-containing protein. (270 aa)
THSD4Thrombospondin type 1 domain containing 4. (687 aa)
BMP7Uncharacterized protein. (395 aa)
ZFYVE9Zinc finger FYVE domain-containing protein. (1418 aa)
FAM151BFYVE-type domain-containing protein. (1792 aa)
LTBP2Latent transforming growth factor beta binding protein 2. (1715 aa)
SMURF1E3 ubiquitin-protein ligase. (730 aa)
RHOAUncharacterized protein. (193 aa)
ENSVURP00010023486E2F_TDP domain-containing protein. (341 aa)
INTS8Uncharacterized protein. (994 aa)
CREBBPUncharacterized protein. (2453 aa)
SMAD3Mothers against decapentaplegic homolog. (426 aa)
SMAD6Mothers against decapentaplegic homolog. (500 aa)
ENSVURP00010022363annotation not available (408 aa)
LOC114049914SNARE-associated protein Snapin; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking and synaptic vesicle recycling; Belongs to t [...] (136 aa)
ENSVURP00010021762annotation not available (509 aa)
SMAD9Mothers against decapentaplegic homolog. (467 aa)
CUL1CULLIN_2 domain-containing protein; Belongs to the cullin family. (775 aa)
ENSVURP00010021329TGFb_propeptide domain-containing protein. (131 aa)
ENSVURP00010021189Left-right determination factor. (370 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (533 aa)
ENSVURP00010020877annotation not available (425 aa)
LOC114045863Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (479 aa)
AMHTGF_BETA_2 domain-containing protein. (640 aa)
LOC114045927Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (511 aa)
SMURF2E3 ubiquitin-protein ligase. (748 aa)
DCNDecorin; May affect the rate of fibrils formation. (356 aa)
ENSVURP00010019930CTCK domain-containing protein. (164 aa)
ENSVURP00010019792Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (299 aa)
LOC114043227-2PLAC domain-containing protein. (1125 aa)
NODALNodal growth differentiation factor. (310 aa)
ENSVURP00010018398annotation not available (151 aa)
ANKFN1Uncharacterized protein. (1146 aa)
ACVR2BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (511 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
ENSVURP00010017759annotation not available (448 aa)
RBL1Uncharacterized protein. (1065 aa)
FMODLRRNT domain-containing protein. (374 aa)
INHBATGF_BETA_2 domain-containing protein. (428 aa)
ENSVURP00010017255annotation not available (170 aa)
RPS6KB1Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (539 aa)
PPP2CBSerine/threonine-protein phosphatase. (309 aa)
LOC114030664Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (448 aa)
INHBBTGF_BETA_2 domain-containing protein. (401 aa)
LOC114031682Homeobox domain-containing protein. (247 aa)
SP1Sp1 transcription factor. (779 aa)
AMHR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (563 aa)
BMP5TGF_BETA_2 domain-containing protein. (455 aa)
SMAD1Mothers against decapentaplegic homolog. (465 aa)
ID2BHLH domain-containing protein. (134 aa)
ENSVURP00010013359Uncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1296 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (408 aa)
LOC114049601Left-right determination factor. (368 aa)
GREM1Gremlin. (184 aa)
PPP2R1AUncharacterized protein. (589 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
THBS1Uncharacterized protein. (1172 aa)
RGMAUncharacterized protein. (450 aa)
SMAD5Mothers against decapentaplegic homolog. (465 aa)
ACVR1BReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa)
PITX1Homeobox protein. (306 aa)
BMP4TGF_BETA_2 domain-containing protein. (410 aa)
PPP2CASerine/threonine-protein phosphatase. (309 aa)
SKP1Uncharacterized protein; Belongs to the SKP1 family. (163 aa)
LOC114049823Gremlin. (168 aa)
MATN2Matrilin 2. (943 aa)
ENSVURP00010008132annotation not available (472 aa)
ENSVURP00010007983annotation not available (411 aa)
LOC114034230Uncharacterized protein. (472 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1040 aa)
FBN1Uncharacterized protein. (2872 aa)
ACVR2ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (513 aa)
PITX2Homeobox protein. (330 aa)
ENSVURP00010005678CTCK domain-containing protein. (272 aa)
Your Current Organism:
Vombatus ursinus
NCBI taxonomy Id: 29139
Other names: V. ursinus, coarse-haired wombat, common wombat
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